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Philip Ruthig

@philipruthig.bsky.social
169 followers 118 following 64 posts

Staff Scientist @erturklab.bsky.social, passionate neuroscientist, Light sheet microscopist, and Python aficionado.

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Reposted by Philip Ruthig
Prof Bill McGuire @profbillmcguire.bsky.social · 26/08/2026
A direct line can be drawn from the fossil fuel corporation CEOs in their smart suits and swanky offices, to the brutal deaths of the terrified people you can see in these films Himalayan glaciers are collapsing, and meltwater lakes breaching, due to global heating www.bbc.co.uk/news/live/c6...
bbc.co.uk
Hundreds missing, including 291 foreign tourists, after deadly flash flood on Nepal-Tibet border
In Tibet, CCTV captured a wall of mud and water hitting a border crossing. The missing in Nepal include more than 100 from India and 12 from the UK.
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Philip Ruthig @philipruthig.bsky.social · 04/08/2026
Got your own (mouse brain-) 3D data from clearing and light sheet imaging, but no idea how to tackle the analysis? We have just the solution for you in Munich: A two-day course on deep learning and VR-assisted segmentation, atlas registration, and so on! Take the course at @erturklab.bsky.social
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Philip Ruthig @philipruthig.bsky.social · 03/08/2026
I entered a contest for a pretty picture! And if you want to help, you can vote for my entry here 😍 awards.helmholtz-imaging.de/site/index.php ("Public Voting" at the top of the site)
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Danielle Beckman @daniellebeckman.bsky.social · 17/06/2026
Not all brains age the same🧐🧠 Using whole-brain 3D imaging combined with spatial proteomics, @erturklab.bsky.social revealed multiple trajectories of cerebrovascular aging. A fascinating new study: biorxiv.org/content/10.6... I'm always excited to share great work from my colleagues! #Neuroscience
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Nature @nature.com · 22/05/2026
Nature research paper: A deep-learning framework reveals whole-body perturbations at cell level go.nature.com/3Pjox61
go.nature.com
A deep-learning framework reveals whole-body perturbations at cell level - Nature
An analysis of diet-induced obesity using MouseMapper—a suite of foundation-model-based deep-learning algorithms—identifies structural alterations of the infraorbital branch of the trigeminal ganglia.
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Ali Maximilian Erturk @erturklab.bsky.social · 15/05/2026
🧠 Does brain aging always mean vessel loss? We found the opposite in some aged brains: maladaptive hypervascularization, linked to cognitive decline and blood-brain barrier damage. Check it out below! www.biorxiv.org/content/10.6...
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Ali Maximilian Erturk @erturklab.bsky.social · 13/05/2026
happy to share our new protocol paper on wildDISCO for whole-body immunolabeling, tissue clearing & 3D imaging of intact mice at cellular resolution using standard IgG antibodies, for mapping of neuronal, vascular, lymphatic and immune systems across the entire body. www.nature.com/articles/s41...
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Philip Ruthig @philipruthig.bsky.social · 07/05/2026
The Ertürk Lab and me are looking for a motivated and skilled Master's Student (with possible PhD extension)! If you are interested in addiction neurobiology, multimodal brain mapping, proteomics, tissue clearing and 3D imaging, please do not hesitate to apply! tinyurl.com/2esspas6
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Philip Ruthig @philipruthig.bsky.social · 04/05/2026
The Ertürk lab is looking for PhD students. Come work with us in Munich :)
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Philip Ruthig @philipruthig.bsky.social · 09/03/2026
Be my colleague! :)
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Helen Czerski @helenczerski.bsky.social · 09/03/2026
Oil prices wouldn't be all over the news today if more of our economy was powered by local, secure renewable energy. This isn't an "energy crisis". It's a fossil fuel crisis. 44% of UK electricity came from renewables in 2025. More of that plus an electrified economy => no more oil shocks.
Crude oil prices, showing a very sharp increase in the last day, from around 65 to 101 dollars per barrel..
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bryson @brysonm.bsky.social · 09/03/2026
holy shit
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Brandy A Freitas @brandy-syglass.bsky.social · 12/02/2026
❤️ A cleared guinea pig heart for #3DThursday! Clearing a heart is HARD — dense muscle, deep antibody labeling, big volume. But to understand coronary networks, you need the whole organ. 🔬: Miltenyi Ultramiscroscope 🥼: Pam Rios Coronado, @pamrc.bsky.social 🏛️: Red-Horse lab @stanford.edu 🎬: #syGlass
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PLOS Biology @plosbiology.org · 23/01/2026
For the record, an earlier version of this post, using Fig 1 from this paper, but without shorts, fell foul of BlueSky's "Adult Content" filter.
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Philip Ruthig @philipruthig.bsky.social · 23/01/2026
Come work with a great team on one of the big questions at Helmholtz Munich! @helmholtzmunich.bsky.social
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Altmetric @altmetric.com · 08/01/2026
X/Twitter's rough full volume is around 500 total million posts every day, or 182 (and a half) billion posts per year. By contracts, we found 11.2 million research posts in all of 2025 on there. In other words, 0.000006% of Twitter appears to be sharing research. Basically zero.
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Rita Strack @ritastrack.bsky.social · 23/12/2025
Very cool paper in NBT from the Dietz and Erturk labs @erturklab.bsky.social @markuselsner.bsky.social go.nature.com/4gNLjeC
go.nature.com
Nanocarrier imaging at single-cell resolution across entire mouse bodies with deep learning - Nature Biotechnology
An integrated experimental and deep learning pipeline reveals cell-level targeting of nanocarriers in whole bodies.
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Ali Maximilian Erturk @erturklab.bsky.social · 08/12/2025
Congratulations to our scientist, Laurent Simons, for earning his PhD in quantum physics at just 15—an exceptional achievement. In our lab, Laurent’s work focuses on in silico biology to accelerate treatment of devastating diseases. We’re thrilled to have him on the team.
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Ali Maximilian Erturk @erturklab.bsky.social · 04/11/2025
We are introducing LipiGo 🤗 A programmable DNA–lipid nanocarrier 🧬 with built-in targeting logic. It de-targets the liver and redirects mRNA delivery into lymphoid organs, enhancing therapies requiring the immune system. Precision delivery at the cell level isn't far! www.biorxiv.org/content/10.1...
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LMU Open Science Center @lmu-osc.bsky.social · 10/09/2025
💡 Explore how practices from distributed, open-source software can make science more professional, open, and collaborative! Attend the “Science as amateur software development” lecture by Prof. Dr. @rmcelreath.bsky.social on Wed 17 Sept, 9:00. 👉 Register here: www.pretix.osc.lmu.de/lmu-osc/OSSS...
Promotional poster for the LMU Open Science Center Summer School 2025 Public Lecture. The poster features a photo of speaker Prof. Dr. Richard McElreath. The text states the lecture focuses on science as amateur software development, time and date of lecture being 9:00-10:00 CEST on Wednesday September 17 2025, and instructions to register online. Logos of LMU Open Science Center, LMU, and Universitätsbibliothek München are displayed at the bottom.
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Philip Ruthig @philipruthig.bsky.social · 30/08/2025
Wrote the same thing as a tweetorial on X, got a single interaction with the tweet. I guess it is finally time to leave that place for good
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PLOS Biology @plosbiology.org · 22/08/2025
#Myelination enables faster signal propagation in the brain, but takes more energy & space. @philipruthig.bsky.social &co reveal how short- & long-range #WhiteMatter fibers differ, showing how these variations affect neural communication & processing efficiency @plosbiology.org 🧪 plos.io/4mq5tOy
Arrangement of raw data, semantic, and instance segmentation of human corpus callosum fibers, acquired by transmission electron microscopy. The data used for this image were generated by Maria Morozova, David Edler von der Planitz, and Philip Ruthig. All cover Art was created by the MPI for Human Cognitive and Brain Sciences Graphics department (Andrea Sandmann)
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Philip Ruthig @philipruthig.bsky.social · 21/08/2025
How are human brain regions connected? Are the connecting axons thicker and more myelinated the longer these connecting fibers are? In our recent paper we find that indeed, they are! Read the skeetorial below ⬇️⬇️⬇️ plos.io/4mq5tOy #neuroscience #neuroskyence #whitematter #deeplearning
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Philip Ruthig @philipruthig.bsky.social · 21/08/2025
Out now in @plosbiology.org: our recent study on white matter myelination and axon diameters in long and short fibers of humans! Skeetorial coming soon :)
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Christophe 🔬 Leterrier @christlet.bsky.social · 14/07/2025
When a microscope facility user asks about how to make a red/green overlay
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Markus Elsner @markuselsner.bsky.social · 23/06/2025
Our spin-off company is hiring a COO. (Stay tuned for more job offers) www.linkedin.com/jobs/view/42...
linkedin.com
Deep Piction hiring Chief Operating Officer in Greater Munich Metropolitan Area | LinkedIn
Posted 10:54:20 AM. Chief Operating Officer (COO)Location: Munich, Germany (On-site) Employment Type: Full-timeAbout…See this and similar jobs on LinkedIn.
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☁️ retornam ☁️ @retornam.bsky.social · 21/06/2025
bsky.app/profile/matt...
Meme showing Principal Skinner from
The Simpsons in two frames. 

The first frame has him with the words "Am I out of touch?"

The second frame has him with the words “No it is the entire corpus of human knowledge that is wrong."
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Josh Moore @joshmoore.bsky.social · 11/06/2025
🚀 We’re hiring again! Join @gerbi-gmb.de as a Software Developer! 💻 Build scalable #bioimaging solutions 🌍 Collaborate globally 🎯 Contribute to open science through #OME #Zarr 📣 Tell your #NGFF friends. Remote, full-time. Apply by 30 June 2025: All submissions via bit.ly/gerbi-jobs-2...
Screenshot of the PDF available at https://cloud.gerbi-gmb.de/s/6LrYfMByymPnHP5/download/2025_OME-Zarr_sw_developer.pdfScreenshot of the PDF available at https://cloud.gerbi-gmb.de/s/y4rBGFM6dXn8Jkr/download/2025_OME-Zarr_web_developer.pdf
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Karl Deisseroth @deisseroth.bsky.social · 30/05/2025
Congratulations to our Human Neural Circuitry team; bit.ly/4dEyX7Z publishes today in Science! This was the hardest challenge of my career, but one of the most rewarding, after years of rebuilding– & expanding my inpatient neuropsychiatry in the service of basic discovery bsky.app/profile/deis...
bit.ly
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Philip Ruthig @philipruthig.bsky.social · 20/05/2025
Signs I am, indeed, living in Munich, pt 1: I just paid 9€ for a pretzel and croissant.
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Blake Richards @tyrellturing.bsky.social · 12/05/2025
+1000 I think AI will help us do scientific research in numerous ways, but the bulk of the work that real scientists do is not anything that "AI scientists" will be able to do.
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Jo Wolff @jowolff.bsky.social · 03/05/2025
Every now again it’s useful to repeat advice about accessing papers that are behind a paywall that excludes you. Email the author. My estimate is that 90% of academics are so thrilled that a living, breathing, possibly even reading, person shows interest that they will swiftly send you a copy.
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Philip Ruthig @philipruthig.bsky.social · 17/04/2025
One of the undisputed scientific wins of the last few years.
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Philip Ruthig @philipruthig.bsky.social · 10/04/2025
Can wholeheartedly recommend the city, place and people to motivated to-be phd students! Don't hesitate to apply 👏👏
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Robert Fledrich @axoglia.bsky.social · 10/04/2025
🚀 Now hiring: 10 Doctoral Researchers @ Leipzig University! 🧠🔬 Join the DFG funded RTG NeuroTune and explore how neurons fine-tune communication! 📍 Start: Oct 1, 2025 🎯 Cutting-edge neuroscience + top-tier mentoring in vibrant Leipzig. Apply now 👉 www.lw.uni-leipzig.de/en/institut-... #NeuroTune
lw.uni-leipzig.de
Universität Leipzig: GRK Neurotune
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PolyBio Research Foundation @polybiorf.bsky.social · 28/03/2025
BREAKING: Development of a spike protein-specific radiolabeled antibody used with PET imaging shows presence of spike in brain & lungs of macaque monkeys 3 months post-COVID; provides new viral reservoir detection opportunity for long COVID: www.nature.com/articles/s41...
nature.com
Whole-body visualization of SARS-CoV-2 biodistribution in vivo by immunoPET imaging in non-human primates - Nature Communications
There are limited approaches to monitor virus spread in vivo. Here, the authors report PET/CT-based in vivo imaging to track SARS-CoV-2 biodistribution in a COVID-19 non-human primate model using a ra...
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Philip Ruthig @philipruthig.bsky.social · 24/03/2025
When I see a notification about an editors email
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Chris Langsdorf @fluorist.bsky.social · 21/03/2025
🌷Spring flowers? Fireworks? Mouse cerebral cortex FFPE tissue was labeled with eight primary antibodies. Aluora Spatial Amplification Kits and DAPI were used for detection, followed by imaging on the EVOS S1000 Spatial Imaging System. 🧠🔬🧪 #Neuroscience #FluorescenceFriday
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Julius Tröger @juliustroeger.bsky.social · 20/03/2025
Wegen großer Nachfrage haben wir nun die Rohdaten hinter "So hat Ihre Gemeinde gewählt" www.zeit.de/politik/deut... -> github.com/ZeitOnline/b... und "So hat Ihr Wahlkreis seit 1949 gewählt" www.zeit.de/politik/deut... -> github.com/ZeitOnline/b... auf Github frei zugänglich gemacht.
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NFDI4BIOIMAGE @nfdi4bioimage.bsky.social · 19/03/2025
Looking for a suitable research software management tool for your PhD? 👨‍💻 Then take a look at the #openaccess lecture slides by @haesleinhuepf.bsky.social and get to know git[hub] to upgrade your software development. 👉 Check out the lecture slides here: zenodo.org/records/1462...
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Nicole Rust @nicolecrust.bsky.social · 13/03/2025
👏👏👏 to the “woke max planck director” @davidpoeppel.bsky.social! “We’re living in a time and an environment in which there are certain shared values that are non-negotiable. And that includes sexist behavior, mobbing; harassment of any kind.”
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David Poeppel @davidpoeppel.bsky.social · 13/03/2025
www.youtube.com/watch?v=n5nE... Important and painful
youtube.com
How Germany's elite research institution fails young scientists | DW Documentary
YouTube video by DW Documentary
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Aitor Morales-Gregorio @aitormg.bsky.social · 11/01/2025
Maybe a good time to remember that mice have tiny hyperconnected brains. An estimated 97% of all possible connections between brain areas exist in mice, vs ~62% in macaques and marmosets. No wonder everything is everywhere in mice, they have all-to-all connectivity! doi.org/10.1093/cerc...
doi.org
The meso-connectomes of mouse, marmoset, and macaque: network organization and the emergence of higher cognition
Abstract. The recent publications of the inter-areal connectomes for mouse, marmoset, and macaque cortex have allowed deeper comparisons across rodent vs.
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John Burn-Murdoch @jburnmurdoch.ft.com · 07/03/2025
NEW: The actions of Trump and Vance in recent weeks highlight something under-appreciated. The American right is now ideologically closer to countries like Russia, Turkey and in some senses China, than to the rest of the west (even the conservative west). My column: www.ft.com/content/3046...
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Richard McElreath 🐈‍⬛ @rmcelreath.bsky.social · 05/03/2025
Seriously talented group of people, building Bayes at scale
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David Poeppel @davidpoeppel.bsky.social · 03/03/2025
20+ years ago, an idea about cortical lateralization of audition was advanced: asymmetric sampling in time (AST). This extensive review/reevaluation by Chantal Oderbolz, me, and Martin Meyer assesses how the idea has fared. #notallwrong www.sciencedirect.com/science/arti...
sciencedirect.com
Asymmetric Sampling in Time: Evidence and perspectives
Auditory and speech signals are undisputedly processed in both left and right hemispheres, but this bilateral allocation is likely unequal. The Asymme…
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Austin E. Y. T. Lefebvre @austin-lefebvre.bsky.social · 27/02/2025
Do you LOVE organelles?? Well I am THRILLED to announce that Nellie has been published in @naturemethods.bsky.social! Nellie a fully automated pipeline for organelle segmentation, tracking, and hierarchical feature extraction in 2D, 3D, timelapse, multichannel live-cell microscopy 🧵1/N
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Philip Ruthig @philipruthig.bsky.social · 28/02/2025
This looks extremely interesting
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Markus Elsner @markuselsner.bsky.social · 26/02/2025
Want to know what we do at our startup Deep Piction? Check out our paper with Denali Therapeutics. Using our proprietary clearing & imaging technologies, we mapped the full targeting profile of brain-penetrating transport vehicles (ATVs) in whole mouse bodies and monkey brains. go.nature.com/3Xifva2
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