Axons require intracellular transport of cargoes between the soma and the terminus. The authors show a related logistical challenge exists at smaller scale with respect to the interaction of process-b...

Myelin pathology in demyelinating diseases is accompanied by lipid remodeling that remains challenging to characterize at spatial level using traditio…

Nature Communications - Polyneuropathy causes are difficult to pinpoint. Here, authors used single-nucleus and spatial transcriptomics of 37 human peripheral nerves to identify focal perineurial...

YAP/TAZ-mediated gene transcription is necessary for Schwann cell laminin receptor expression and differentiation. Weaver et al. use transgenic mouse models to show that the STRIPAK complex is required to regulate YAP/TAZ and facilitate radial sorting.…

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The three-dimensional visualization of cellular architecture by volume electron microscopy (vEM) has reignited interest in morphological descriptions of complex tissue. At the same time, the increasin...

Robert Fledrich, neuroscientist and professor at the Institute of Anatomy at Leipzig University’s Faculty of Medicine, has been awarded an ERC Consolidator Grant by the European Research Council (ERC)...