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pglekas.eurosky.social

@pglekas.eurosky.social
21 followers 35 following 22 posts
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Victor de Lorenzo (CNB, Madrid) @vdlorenzo.bsky.social · 26/09/2026
Experimental evolution—often called with IMHO bland name 'adaptive laboratory evolution' or ALE—reaches out & creates outcomes to multi-objective optimization issues not amenable to rational engineering. Here a new genet tool to explore solution spaces without SOS response dx.doi.org/10.1111/1751...
dx.doi.org
Accelerated Adaptive Evolution of Gram‐Negative Bacteria With a Broad‐Host‐Range Dual Base Editor
We developed a broad-host-range dual base editor that transiently induces genome-wide hypermutation, accelerating adaptive laboratory evolution by up to four orders of magnitude. The platform rapidly...
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pglekas.eurosky.social @pglekas.eurosky.social · 24/09/2026
21,627 applications for the latest #MSCA Postdoctoral Fellowships call. If each proposal takes ~100 hours to prepare, ~ 2.1 million hours of researchers’ time spent writing applications for a success rate reportedly around 7–8%. Is the best use of early-career researchers’ time? (1/2)
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pglekas.eurosky.social @pglekas.eurosky.social · 11/09/2026
Can confirm! Stay tuned! 😎
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Reposted by @pglekas.eurosky.social
Victor de Lorenzo (CNB, Madrid) @vdlorenzo.bsky.social · 07/09/2026
If we keep on advocating the benefits of Eng Microbes for Env Release with the same arguments that we had for 50 yr, no wonder we will also get the same social backlash. A new narrative is badly needed focused on partnership & stewardship—not just containment & control dx.doi.org/10.1111/1751...
dx.doi.org
Environmental Release of Genetically Intervened Microorganisms: Towards a New Narrative
From control to partnership: Rethinking the environmental release of laboratory-trained microorganisms for bioremediation.
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pglekas.eurosky.social @pglekas.eurosky.social · 10/07/2026
An unbelievable experience! Highly recommend!
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Angel Goñi-Moreno @angelgm.eurosky.social · 16/06/2026
The 2026 Systems Biology Department's retreat. What a brilliant crowd! The t-shirt (artist: Marina de la Fuente) has a logo of every lab in the Dept. Our Lab is The logic Doors :-) Kudos to organizers: @angeles-hg.bsky.social, @pglekas.eurosky.social, @lewisgrozinger.bsky.social & Guillermo Gomez.
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Victor de Lorenzo (CNB, Madrid) @vdlorenzo.bsky.social · 02/06/2026
The 1st tangible outcome of my minisabbatical at @core-rwth.bsky.social surrounded by philosophers & social scientists. Can SynBio be an instrument not of domination but of partnership wth the natural world? I believe so, but a new narrative needs to be developed and its consequences taken seriously
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Victor de Lorenzo (CNB, Madrid) @vdlorenzo.bsky.social · 26/05/2026
I am growingly convinced that GM bacteria for release as bioremediation agents must have a separate regulatory frame compared to other GM items, as their only purpose and moral value is doing good things for the society, the environment and helping restoring ecological balance 🤔
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Angel Goñi-Moreno @angelgm.eurosky.social · 22/05/2026
📣 Latest paper out! I'll write a thread about it next week: growth control, cellular context, genetic circuits... A fascinating story by @angeles-hg.bsky.social & @mirobueno.bsky.social #synbio #biocomputation link.springer.com/article/10.1...
link.springer.com
Growth control as a central regulator for tuning the cellular context - Journal of Biological Engineering
The cellular context decisively shapes genetic circuit performance, but the interplay between host and circuit remains difficult to control rationally. To address this challenge, we replaced the nativ...
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Reposted by @pglekas.eurosky.social
Victor de Lorenzo (CNB, Madrid) @vdlorenzo.bsky.social · 12/05/2026
Join us this Oct with @pabnik.bsky.social & Guo-Qiang Chen www.chemeng.tsinghua.edu.cn/en/info/1026... at @cshlaboratory.bsky.social Asia in Suzhou to explore ongoing cutting-edge research at the frontier of biotechnology beyond containment with global researchers & help shaping the future of SynBio
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Reposted by @pglekas.eurosky.social
Victor de Lorenzo (CNB, Madrid) @vdlorenzo.bsky.social · 09/04/2026
Please note the seminars on SynBio and Metabol Eng Tools this April 24 Organized by ESAB. You can register in esabweb.org/webinars/68)
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Reposted by @pglekas.eurosky.social
Victor de Lorenzo (CNB, Madrid) @vdlorenzo.bsky.social · 18/03/2026
Two PhD positions offered at the amazing @pabnik.bsky.social Lab in DTU Denmark to work in frontine metabolic engineering of Pseudomonas putida—one is the sexiest, if not the sexiest 😉 SynBio platform! Check efzu.fa.em2.oraclecloud.com/hcmUI/Candid... and efzu.fa.em2.oraclecloud.com/hcmUI/Candid...
efzu.fa.em2.oraclecloud.com
PhD scholarship in Synthetic Metabolism for Extending the Metabolic Landscape of Bacterial Cell Factories - BRIGHT
Are you ready to make a difference for a sustainable future through bacterial metabolic engineering? The Systems Environmental Microbiology (SEM) group at DTU (BRIGHT) seeks a candidate for a 3-year, ...
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pglekas.eurosky.social @pglekas.eurosky.social · 04/03/2026
www.intracomdefense.com/ide-at-senti... Proud to be part of the AEOLIKI team in the SENTINEL consortium. The 1st All Partners Event brought 130+ participants from 16 countries together to advance resilient, sustainable energy solutions for defence. #AEOLIKI #SENTINEL
intracomdefense.com
IDE at SENTINEL 1st All Partners Event – INTRACOM DEFENSE
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pglekas.eurosky.social @pglekas.eurosky.social · 12/02/2026
Deep desulfurization is key for cleaner fuels. Our latest review highlights how synthetic biology is bringing biodesulfurization closer to real-world application as a greener complement to conventional refining. doi.org/10.1016/j.co...
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Reposted by @pglekas.eurosky.social
Victor de Lorenzo (CNB, Madrid) @vdlorenzo.bsky.social · 10/02/2026
The times they are a-changin'… The result of the first debate at this side of the pond on the need to revisit old ideas and regulations re engineering & release of microorganisms as agents of environmental bioremediation 👉🏻 www.nympheproject.eu/post/beyond-...
nympheproject.eu
Beyond GMOs: How Laboratory-Trained Bacteria Could Transform Environmental Remediation - workshop summary
On 3 February 2026, researchers, regulators and policy specialists gathered in Brussels to examine a rapidly evolving question at the intersection of biotechnology and environmental governance: how sh...
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Reposted by @pglekas.eurosky.social
Victor de Lorenzo (CNB, Madrid) @vdlorenzo.bsky.social · 27/01/2026
How do you react when your favorite microbe is renamed by taxonomists who are completely outside your field—and who ignore the community that actually works with it? Here is our clear answer re the case of Pseudomonas putida KT2440 👉🏻 journals.asm.org/doi/10.1128/...
journals.asm.org
The disputed identity of Pseudomonas putida KT2440: when taxonomists rename your favorite microbe | mBio
Names matter; they are not mere labels. They operate as anchors of memory, social coordinates, and references of collective identity. When a name becomes established through long-term use and broad ad...
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Victor de Lorenzo (CNB, Madrid) @vdlorenzo.bsky.social · 03/01/2026
Time to leverage SynBio for tacking environmental pollution. But releasing bioengineered microorganisms still raises alarms. A new narrative is badly needed: bacteria for bioremediation are not alien intrusions but laboratory-trained extensions of life’s creativity link.springer.com/10.1038/s443...
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Victor de Lorenzo (CNB, Madrid) @vdlorenzo.bsky.social · 16/12/2025
Pre-Xmas lunch for celebratimg with the Lab folk all we have achieved in 2025. The best of this job is being surrounded by such talented people 😍
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Reposted by @pglekas.eurosky.social
Victor de Lorenzo (CNB, Madrid) @vdlorenzo.bsky.social · 15/12/2025
We all start by cloning something into a plasmid. But the vector you choose matters more than you think. A Commentary from the battleground with my colleague & curator of the @sevaplasmids.bsky.social collection, Esteban Martínez enviromicro-journals.onlinelibrary.wiley.com/doi/10.1111/...
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Victor de Lorenzo (CNB, Madrid) @vdlorenzo.bsky.social · 21/11/2025
Time to rethink prevailing views re regulations on GE & SynBio microbes for env bioremediation in an era of climate change. We must move from a mindset of control & domination to one of stewardship & negotiation. Indigenous perspectives can help in bridging the artificial–natural divide. Stay tuned!
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SEVA Plasmids @sevaplasmids.bsky.social · 14/11/2025
🚨 News on bioremediation! A study published in Nature reveals how by genetically modifying the bacterium Vibrio natriegens, it simultaneously degrades five toxic contaminants in industrial wastewater and saline soils. Read the full article: www.nature.com/articles/d41...
nature.com
Engineered bacteria can degrade five wastewater pollutants at the same time
Five gene clusters have been introduced into a single rapidly growing bacterial strain.
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Reposted by @pglekas.eurosky.social
Victor de Lorenzo (CNB, Madrid) @vdlorenzo.bsky.social · 28/10/2025
The scientific & ethical legacy of the late Ioannis Economidis—a champion of Env Biotech & SynBio at the @ec.europa.eu —is captured in this article, based on his last lecture. A testament to an exceptional mind & a remarkable human being enviromicro-journals.onlinelibrary.wiley.com/doi/full/10....
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Victor de Lorenzo (CNB, Madrid) @vdlorenzo.bsky.social · 15/10/2025
The recently published report on Biosecurity by Drew Endy et al in the context of contemporary & future Biotech & SynBio is worth every word. Check it out 👉🏻 www.hoover.org/research/bio...
hoover.org
Biosecurity Really: A Strategy for Victory
Current trends make clear that biosecurity will become much more challenging over the next several years. We must act strategically to secure biology—before it becomes a general-purpose technology. Dr...
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Reposted by @pglekas.eurosky.social
Microbial Biotechnology (MBT) @microbiotech.bsky.social · 24/09/2025
#MicroSky: CLEAN ENVIRONMENT! Glekas et al built a Pseudomonas putida strain with an optimized dsz operon to strip sulfur from fuels. The new strain, DS006, shows high efficiency in removing DBT—paving the way for cleaner & greener energy. doi.org/10.1111/1751...
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pglekas.eurosky.social @pglekas.eurosky.social · 21/09/2025
Grateful to the organizers @vdlorenzo.bsky.social @pabnik.bsky.social, instructors, and host @cshlaboratory.bsky.social of the CSH-Asia workshop. It was an incredible experience for young scientists diving into synthetic biology and the metabolic engineering of Pseudomonas. (1/n)
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Victor de Lorenzo (CNB, Madrid) @vdlorenzo.bsky.social · 12/09/2025
Bio-desulfurization of fossil fuels has been a classic env biotech challenge for decades, but the field became stagnant for a while … until @pglekas.bsky.social et al leveraged SynBio tools to develop superior whole-cell catalysts enviromicro-journals.onlinelibrary.wiley.com/doi/10.1111/... 😱
enviromicro-journals.onlinelibrary.wiley.com
Boosting Dibenzothiophene Biodesulfurization Through Implantation of a Refactored DBT Pathway in a Tailored Pseudomonas putida Chassis
This study engineered a Pseudomonas putida strain to efficiently remove sulfur from dibenzothiophene (DBT) by reordering and optimising the dsz operon from Rhodococcus qingshengii IGTS8, enhancing ca...
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Angel Goñi-Moreno @angelgm.eurosky.social · 09/07/2025
Next in Lab's conference agenda: FEMS @femsmicro.org! @vdlorenzo.bsky.social and myself are running a session on bacterial computation. Talks by @yschaerli.bsky.social, @manishmicrobe.bsky.social, Sangram Bagh & organisers. Very looking forward to it! #biocomputation #synbio
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Victor de Lorenzo (CNB, Madrid) @vdlorenzo.bsky.social · 09/07/2025
Deadline for applications extended to July 22 🔔! An unique opportunity to engage with cutting-edge science in a highly interactive format 👇
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Saganism @sagan.bsky.social · 05/06/2025
Carl Sagan in 1986 on the problems with media and science literacy.
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Angel Goñi-Moreno @angelgm.eurosky.social · 30/05/2025
We are offering a #PhD candidate position (Spanish FPI) to work with us at the @cnb-csic.bsky.social in Madrid. The project you would be part of: establish a #biofoundry at our institution, to optimize #synbio experiments from #design to #test. If interested, get in touch!
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Victor de Lorenzo (CNB, Madrid) @vdlorenzo.bsky.social · 26/05/2025
Today by 12 h @cnb-csic.bsky.social our Tomás Aparicio will share his latest insights & genetic tools on how to accelerate evolution without stress in individual bacteria and communities—what we call *hit-and-run mutagenesis* 🤩 thereby revisiting the discussion of what is a GMO 😱
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Victor de Lorenzo (CNB, Madrid) @vdlorenzo.bsky.social · 22/05/2025
Is there life in the bioscience research landscape other than being a PI? Find out with @aemonten.bsky.social, who will give a talk in the @cnb-csic.bsky.social this Fri on his experiences as Executive Editor CSH Protocols & Head of the Integrity in Publishing Group of the CSHL Press
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pglekas.eurosky.social @pglekas.eurosky.social · 06/05/2025
The Secretary of Education just went full OP-ed in a letter to Harvard. Foreign chaos, remedial math, and Bill Ackman as fiscal Yoda. Somewhere in there was a point about grants? When academia meets political fanfic....
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Victor de Lorenzo (CNB, Madrid) @vdlorenzo.bsky.social · 30/04/2025
Dear Pseudomonas aficionados: Please check this hands-on Cold Spring Harbor Asia Course on the sexiest science and technology of our favourite bug. All info in the QR code 👇
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Carlos Briones @brionesci.bsky.social · 26/03/2025
“No existe el cambio climático. Siempre ha llovido en Europa durante febrero y marzo.” Ya, pero:
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Pablo Ivan Nikel @pabnik.bsky.social · 19/03/2025
A call for action by Ken Timmis — Academic institutions worldwide must welcome de-funded US researchers · Read the statement here 👇 iums.org/kenneth-timm...
iums.org
Academic institutions worldwide must welcome de-funded US researchers
Academic institutions worldwide must welcome de-funded US researchers
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Victor de Lorenzo (CNB, Madrid) @vdlorenzo.bsky.social · 19/03/2025
Keep an eye out for the Special Sessions of the European Academy of Microbiology this July at FEMS2025 fems-microbiology.org/eam-sessions... ! Do not miss the one on bacterial computation, featuring top experts @angelgm.bsky.social, Manish Kushwaha, Yolanda Schaerli, and Sangram Bagh!
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Trish Greenhalgh @trishgreenhalgh.bsky.social · 04/03/2025
The most extraordinary thing about James Harrison, who donated his rare plasma every 2 weeks for over 60 years and saved the lives of an estimated 2.4 million babies, is that he had to overcome a FEAR OF NEEDLES. www.independent.co.uk/news/world/a...
independent.co.uk
James Harrison, whose rare blood helped save millions of babies, dies at 88
By donating blood over 1,100 times, James Harrison helped develop Anti-D, a life-saving treatment for newborns at risk of Rhesus disease
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Santiago Elena @sfelena.bsky.social · 20/02/2025
Experimental evolution of evolvability | Science www.science.org/doi/10.1126/...
science.org
Experimental evolution of evolvability
Evolvability—the capacity to generate adaptive variation—is a trait that can itself evolve through natural selection. However, the idea that mutation can become biased toward adaptive outcomes remains...
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ASM @asm.org · 15/02/2025
ASM stands firm in its commitment to diversity, equity and inclusion, as such efforts are critical to advancing the microbial sciences for everyone. Read our statement: asm.org/Press-Releas...
asm.org
ASM’s Commitment to Diversity, Equity and Inclusion
The American Society for Microbiology stands firm in its commitment to diversity, equity and inclusion, as such efforts are critical to advancing the microbial sciences for everyone.
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Victor de Lorenzo (CNB, Madrid) @vdlorenzo.bsky.social · 04/02/2025
Tomorrow Wes Feb 5 we will enjoy in the @cnb-csic.bsky.social the impromptu Seminar of the one and only Tae Seok Moon, of the JC Venter Institute www.jcvi.org/media-center... in the context of his ongoing International Tour x.com/moon_synth_b...
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Victor de Lorenzo (CNB, Madrid) @vdlorenzo.bsky.social · 29/01/2025
Leveraging AI for Systems & Synthetic Biology 🤔? Learn about the latest developments in the upcoming annual Colloquium of our Sys Bio Department this Feb 14. Starring @hsalis.bsky.social as opening speaker and featuring @alfonsovalencia.bsky.social along with other luminaries in the field 😱!
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Victor de Lorenzo (CNB, Madrid) @vdlorenzo.bsky.social · 12/12/2024
Pre-Xmas Lab lunch incl farewell of Karin Schann, @sebwenk.bsky.social, @glekasp.bsky.social & Fra Demaria. We will miss you in 2025 😢. So privileged to work with this super-special bunch of people 👇
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