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Yolanda Schaerli

@yschaerli.bsky.social
836 followers 169 following 38 posts

Synthetic biologist, Associate Professor at University of Lausanne, Switzerland www.yschaerli.com

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Reposted by Yolanda Schaerli
fbm-unil.bsky.social @fbm-unil.bsky.social · 17/09/2026
🦠 How can we measure #nutrient #availability at the scale of individual #gut #bacteria? New publication @dmf-unil.bsky.social in @plosbiology.org on #honeybee 🐝 by research groups @pengellab.bsky.social & @yschaerli.bsky.social 👉 journals.plos.org/plosbiology/...
journals.plos.org
An engineered bacterial symbiont maps micron-scale sugar gradients in the honeybee gut
A prior PLOS Biology study engineered bee gut bacteria to sense their microenvironment. This new study engineers a native honey bee symbiont into a living biosensor for arabinose, revealing its spatia...
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Reposted by Yolanda Schaerli
PLOS Biology @plosbiology.org · 17/09/2026
In a prior #PLOSBiology study, @yschaerli.bsky.social @pengellab.bsky.social &co engineered #bee gut bacteria to sense their microenvironment. plos.io/3P8ioWJ In their new study, they engineer a native honey bee symbiont into a living #biosensor for arabinose. plos.io/4gXz0Pt 🧪
Macro photograph of a honeybee. Image credit: Bart Zijlstra, UNIL
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Yolanda Schaerli @yschaerli.bsky.social · 02/09/2026
Excited to share our latest preprint! 🧫 We move beyond observing bacterial Voronoi patterns to actively controlling gaps, anti-gaps, curved boundaries, asymmetric structures, seedless regions, and complex composites. @dmf-unil.bsky.social @fbm-unil.bsky.social www.biorxiv.org/content/10.6...
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Yolanda Schaerli @yschaerli.bsky.social · 25/05/2026
Happy to see our peer-reviewed preprint “An engineered multi-step differentiation program in Escherichia coli for self-organized spatial patterning” published: doi.org/10.7554/eLif... (A revised version will soon follow.) @dmf-unil.bsky.social @fbm-unil.bsky.social
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Marlen Knobloch @knoblochlab.bsky.social · 29/04/2026
📣 Job announcement: we have an open Postdoctoral position in the field of neural stem cell metabolism! Motivated candidates should apply through the official platform under this link, where you can also find more informations: career5.successfactors.eu/career?compa... Please help spread the word!
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Reposted by Yolanda Schaerli
Sara Mitri @saramitri.bsky.social · 22/04/2026
Check out Snorre's latest preprint: www.biorxiv.org/content/10.6... I love this story: our 4-species synthetic bacterial community coexists across many simple environments and conditions. We show why (spoiler in the title)
biorxiv.org
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Reposted by Yolanda Schaerli
Sonja Lehtinen @sonjalehtinen.bsky.social · 14/04/2026
Interested in predicting the dynamics of antibiotic resistance? Come work with us! We're looking for two postdocs to develop predictive models of resistance. We're interested in a range of approaches (mathematical & statistical modelling, causal inference, machine learning). tinyurl.com/6c4y3jke
tinyurl.com
Career Opportunities: Postdoctoral positions in predictive modelling of antibiotic resistance spread (22755)
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Yolanda Schaerli @yschaerli.bsky.social · 12/04/2026
Interested in synthetic biology & microbiomes? 🧬🧫 We are recruiting a PhD student to develop biosensors to study microbe–microbe & microbe–host interactions. In beautiful Lausanne, Switzerland🏔️⛵ @dmf-unil.bsky.social @fbm-unil.bsky.social Apply by 24.05.2026 👇 shorturl.at/6X7M4 Boosts appreciated!
shorturl.at
Career Opportunities: PhD position in microbial synthetic biology (22753)
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Reposted by Yolanda Schaerli
Life Sciences Switzerland (LS2) @lifesciswitzerland.bsky.social · 27/02/2026
Register for Theory across Biology 2026: 12 June, Bern. One-day meeting on mathematical & theoretical approaches in biology with chalk talks and flip-chart sessions. Ideal for theorists, modelers, and interdisciplinary biologists. Abstracts by: 10 May 2026 Register by: 24 May 2026: buff.ly/svAZ8NF
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Reposted by Yolanda Schaerli
Christian Fankhauser @chfankhauser.bsky.social · 23/02/2026
I have a PhD student and a post-doc position available in my lab to work on plant photobiology. Please use the links below to postulate. Please RT, many thanks career5.successfactors.eu/career?caree... career5.successfactors.eu/career?caree...
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Reposted by Yolanda Schaerli
Life Sciences Switzerland (LS2) @lifesciswitzerland.bsky.social · 28/01/2026
Register for Theory across Biology 2026: 12 June, Bern. One-day meeting on mathematical & theoretical approaches in biology with chalk talks and flip-chart sessions. Ideal for theorists, modelers, and interdisciplinary biologists. Abstracts by: 10 May 2026 Register by: 24 May 2026: buff.ly/svAZ8NF
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Reposted by Yolanda Schaerli
Jan-Willem Veening @veeninglab.com · 20/01/2026
The @dmf-unil.bsky.social is supporting the application of a candidate for the SNSF/ERC Starting Grant (deadline 5th of May). Reach out to me if you are interested. We are collecting CV’s until the 8th of Feb. We can offer a stimulating scientific environment and help with the application/interview.
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Reposted by Yolanda Schaerli
Sara Mitri @saramitri.bsky.social · 02/12/2025
New preprint from our lab www.biorxiv.org/content/10.1...! Andrea Dos Santos and Clément Vulin combine experiments and models showing how adding glucose can strengthen negative interactions between microbial species. This can be used in tandem with antibiotic treatment to inhibit pathogens!
Diagram illustrating "feed the enemy's enemy": ampicillin inhibits Pseudomonas aeruginosa. Citrobacter freundii acidifies the environment, further inhibiting P. aeruginosa.
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Yolanda Schaerli @yschaerli.bsky.social · 22/12/2025
🚨 New preprint! 🚨 Closing out the year strong with our last pre-print of 2025: a multi-step differentiation program in E. coli for self-organized spatial patterning. Congratulations to all authors🎉 @dmf-unil.bsky.social @fbm-unil.bsky.social
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Reposted by Yolanda Schaerli
Jan-Willem Veening @veeninglab.com · 19/12/2025
Now online @natmicrobiol.nature.com! www.nature.com/articles/s41...
nature.com
Pneumococcal S protein coordinates cell wall modification and repair to resist host antimicrobials - Nature Microbiology
Streptococcal S protein activates a peptidoglycan cell wall repair and modification complex to promote resistance of Streptococcus pneumoniae to lysozyme and LL-37, and increase virulence during infec...
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Yolanda Schaerli @yschaerli.bsky.social · 17/12/2025
New preprint! 🐝 We engineered a bacterial biosensor to reveal micron-scale arabinose gradients in the honeybee gut. Congratulations to Audam and all co-authors. Great collaboration with @pengellab.bsky.social as part of the NCCR Microbiomes at @fbm-unil.bsky.social www.biorxiv.org/content/10.1...
biorxiv.org
Engineered symbiont biosensor maps micron-scale sugar gradients in the honeybee gut
The honeybee gut microbiota plays a key role in shaping host health and susceptibility to disease. Yet, the nutrient environment it experiences within the gut remains poorly characterized. In particul...
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Yolanda Schaerli @yschaerli.bsky.social · 30/11/2025
Really looking forward to hosting Elisabeth on Monday Dec 1 at @fbm-unil.bsky.social @unil.bsky.social for our BIG seminar: 12.15 in Genopode C (note change of room). Open to everyone.
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Yolanda Schaerli @yschaerli.bsky.social · 03/11/2025
So proud of our UNILausanne iGEM team! 🏆🥇 Best Entrepreneurship, placed in the Top 10 Overgrad teams, won a Gold Medal, and were nominated for Best Education, Best Wiki, and Best Biomanufacturing Project. Incredible achievement! #iGEM @fbm-unil.bsky.social @unil.bsky.social
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Yolanda Schaerli @yschaerli.bsky.social · 27/10/2025
Happy to share our latest preprint! Oscillators as building blocks: we model how intracellularly coupled oscillators interact and predict complex behaviors, from beats to chaos, guiding the next generation of synthetic biological circuits. @dmf-unil.bsky.social www.biorxiv.org/content/10.1...
biorxiv.org
Intracellularly Coupled Oscillators for Synthetic Biology
Synthetic biology aims to engineer or re-engineer living systems. To achieve increasingly complex functionalities, it is beneficial to use higher-level building blocks. In this study, we focus on osci...
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Yolanda Schaerli @yschaerli.bsky.social · 27/10/2025
Want to explore synthetic circuit modeling but lack programming experience? Meet GRN_modeler: a user-friendly tool with a graphical user interface to design and analyze gene network models, from dynamics to spatial patterns! @dmf-unil.bsky.social www.embopress.org/doi/full/10....
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Cauã Westmann @cauawest.bsky.social · 20/10/2025
I’m excited to announce the launch of my lab at EPFL in Jan 2026 🎉. We’ll combine evolution & synthetic biology to study and (re)engineer bacterial communication. I’m recruiting PhD students to start in the first semester of 2026. Apply via EPFL PhD programs by Nov 1 drive.google.com/file/d/1cm-t...
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UPF Medicine and Life Sciences @melisupf.bsky.social · 13/10/2025
Really cool job offers here! 👇 📣A PhD and a postdoc positions offered in @santosmoreno-j.bsky.social's lab to go beyond #SyntheticBiology and program time in cells 🕘🦠 Both positions are funded by @erc.europa.eu Come and join the @upf.edu & @prbb.org communities!
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Javier Santos Moreno @santosmoreno-j.bsky.social · 09/10/2025
1 #PostDoc position to develop synthetic gene circuits to program time in cells, as part of the TICK-TOCK Do and Die project @ERC_Research See details here: www.upf.edu/documents/d/...
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Javier Santos Moreno @santosmoreno-j.bsky.social · 09/10/2025
🚨Job alert! 🔬We have 2 new open positions (1 PhD, 1 postdoc) in our team (santosmorenolab.org) in Barcelona @upf.edu @prbb.org funded by @erc.europa.eu If you are passionate about #SynBio and #GeneCircuits, apply now! (until Oct. 26th) 🦠🔧 Info below 👇Please RT!
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Yolanda Schaerli @yschaerli.bsky.social · 09/10/2025
Highly recommended👇
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Reposted by Yolanda Schaerli
Tung Le @tunglejic.bsky.social · 03/10/2025
Independent research fellowships leading to tenured positions at the John Innes Centre. Repost = nice. Thank you very much!!!
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Alex Fedorec @ajfedorec.bsky.social · 29/09/2025
The advert for the second (wetlab) postdoc is now live www.ucl.ac.uk/work-at-ucl/...
ucl.ac.uk
UCL – University College London
UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).
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Yolanda Schaerli @yschaerli.bsky.social · 10/09/2025
Happy to share Estelle’s review on how we can use synthetic and engineered communities to learn about microbial spatial organization. @fbm-unil.bsky.social @dmf-unil.bsky.social
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Yolanda Schaerli @yschaerli.bsky.social · 10/09/2025
Deciphering microbial spatial organization: insights from synthetic and engineered communities url: academic.oup.com/ismecommun/a...
academic.oup.com
Deciphering microbial spatial organization: insights from synthetic and engineered communities
Abstract. Microbial communities are frequently organized into complex spatial structures, shaped by intrinsic cellular traits, interactions between communi
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Yolanda Schaerli @yschaerli.bsky.social · 10/09/2025
Excited to finally share the typeset version of our very first venture into microbial ecology! 🤩 Big thanks to @simonvanvliet.bsky.social for a rewarding collaboration within the NCCR Microbiomes. @fbm-unil.bsky.social @dmf-unil.bsky.social
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Yolanda Schaerli @yschaerli.bsky.social · 10/09/2025
Uptake and leakage rates differentially shape community arrangement and composition of microbial consortia url: academic.oup.com/ismej/articl...
academic.oup.com
Uptake and leakage rates differentially shape community arrangement and composition of microbial consortia
Abstract. Bacteria often grow as communities in intricate spatial arrangements on surfaces and interact with each other through the local exchange of diffu
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Reposted by Yolanda Schaerli
Christian Kost @kostchristian.bsky.social · 08/08/2025
I am excited to announce that the position of a senior postdoc (3 +3 years) in the field of theoretical biology is available in my group. The position provides the opportunity to closely interact with experimentalists and develop own research projects. Please RT. Details 👇: shorturl.at/iiiOv
shorturl.at
116 FB 5 Research Assistant (m/f/d) field of Theoretical Ecology and Evolution or Computational Biology: Uni Osnabrück
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Jake Cornwall-Scoones @jcornwallscoones.bsky.social · 03/07/2025
Can using synthetic approaches to build biology help teach us the design principles of how embryos build themselves? 👷‍♀️🔧 If this is a question that interests you, come and share your thoughts at this Royal Society Workshop on Generative Biology royalsociety.org/science-even...
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Justine Collier @justinecollier.bsky.social · 28/07/2025
🔬 🧫 The Collier lab is hiring a new Postdoc! 🧬 🧪 We are looking for a motivated candidate to study mechanisms controlling DNA replication in Alphaproteobacteria with complex genomes. --> Apply by 30th August 2025 using this link: tinyurl.com/y5e5pm59
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Victor de Lorenzo (CNB, Madrid) @vdlorenzo.bsky.social · 15/07/2025
Four leading researchers on bacterial computing in the @femsmicro.org Workshop on the the topic during the Congress—quite amazing talks by @angelgm.bsky.social, Yolanda Schaerli, Manish Kushwaha & Samgram Bagh. Do bacteria compute? Can we make them to compute wth our logic or do they have their own?
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Tom Ellis @proftomellis.bsky.social · 30/06/2025
We're hiring for 2 postdocs to work in our lab in London on the newly announced Wellcome Trust SynHG project. If you know people looking to work on big-scale ambitious science like this, please RT and share this with them. Apply by 7/20, interviews in Aug. imperial.ac.uk/jobs/search-...
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DMF UNIL @dmf-unil.bsky.social · 10/06/2025
Come join us in beautiful Lausanne! Deadline for applications: August 10th, 2025 wwwfbm.unil.ch/releve/appli...
wwwfbm.unil.ch
DMF: Tenure Track Assistant Professor towards Associate Professor in Molecular Microbiology - Site des postulations FBM
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Jan-Willem Veening @veeninglab.com · 10/06/2025
New tenure track assistant professor position in molecular microbiology in our department @dmf-unil.bsky.social @unil.bsky.social! We are casting a wide net for an experimental molecular microbiologist. Apply here: wwwfbm.unil.ch/releve/appli...
wwwfbm.unil.ch
DMF: Tenure Track Assistant Professor towards Associate Professor in Molecular Microbiology - Site des postulations FBM
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Life Sciences Switzerland (LS2) @lifesciswitzerland.bsky.social · 27/05/2025
If you wish to attend the only #Systems #Biology meeting in #Switzerland this year, there are still a couple of days left to register to the Swiss Systems Biology Symposium! Register now and bring along a #poster to showcase your work! meetings.ls2.ch/systems-biol...
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Manish Kushwaha @manishmicrobe.bsky.social · 10/05/2025
We are hiring for a funded PhD in design of cross- and multi-species genetic circuits. #PhD #synbio #crossspecies #multispecies #biocomputing #circuits #pathways @inrae-france.bsky.social @parissaclay.bsky.social Details here: www.cellularcomputing.team/joinus/
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ross @rosscloney.bsky.social · 02/05/2025
Engineering intercellular communication using M13 phagemid and CRISPR-based gene regulation for multicellular computing in Escherichia coli www.nature.com/articles/s41...
nature.com
Engineering intercellular communication using M13 phagemid and CRISPR-based gene regulation for multicellular computing in Escherichia coli - Nature Communications
Engineering multicellular consortia, where information processing is distributed across specialized cell types, offers a promising strategy for implementing sophisticated biocomputing systems. Here th...
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Sonja Lehtinen @sonjalehtinen.bsky.social · 28/04/2025
Come work with us! We're looking of postdoc(s) with experience in bacterial genomics and interest in mathematical modelling to work on bacterial ecology and evolution in the context of public health. tinyurl.com/n34vzszu
tinyurl.com
Opportunités de carrière : Postdoctoral researcher in bacterial genomics (22209)
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Life Sciences Switzerland (LS2) @lifesciswitzerland.bsky.social · 16/04/2025
If you work in Systems Biology, join our Swiss Systems Biology Symposium on June 19, 2025! ❗Early Career researchers are especially welcome, we have plenty of talk spots for you! ‼️ Abstract submission deadline has been extended until 27.04.2025. ‼️ ▶️ Register: meetings.ls2.ch/systems-biol...
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Yolanda Schaerli @yschaerli.bsky.social · 15/04/2025
Very happy to share our newly published work! We engineered phages for intercellular communication in multicellular consortia and integrated it with CRISPR-based gene regulation for biocomputing. Congratulations to @astrikusuma.bsky.social @dmf-unil.bsky.social @fbm-unil.bsky.social rdcu.be/ehORO
rdcu.be
Engineering intercellular communication using M13 phagemid and CRISPR-based gene regulation for multicellular computing in Escherichia coli
Nature Communications - Engineering multicellular consortia, where information processing is distributed across specialized cell types, offers a promising strategy for implementing sophisticated...
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Yolanda Schaerli @yschaerli.bsky.social · 09/04/2025
The first version of this post had a broken link and I deleted it. Please spread again this corrected version. Thanks😊.
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Yolanda Schaerli @yschaerli.bsky.social · 09/04/2025
🚨We have a fully funded open PhD position in bacterial synthetic biology available in our lab (www.yschaerli.com) in beautiful Lausanne, Switzerland @dmf-unil.bsky.social @fbm-unil.bsky.social @unil.bsky.social If you are passionate about #SynBio and #GeneCircuits, apply here: tinyurl.com/mry2xwa5
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Yolanda Schaerli @yschaerli.bsky.social · 09/04/2025
Correct link: tinyurl.com/mry2xwa5
tinyurl.com
Career Opportunities: PhD position in bacterial synthetic biology (22236)
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Thomas Gorochowski @chofski.bsky.social · 28/03/2025
Looking for a PhD? I have a fully funded one for UK nationals on engineering gene circuits in probiotic microbes. Will bring together a lot of existing stands of #synbio research in my group and push towards some exciting applications! Start date Sept 2025. Email me if interested! Pls RT
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