IntroductionChronic itch is a major burden, impacting the quality of life for one in four adults, and is closely associated with increased levels of anxiety,...

G protein-coupled receptors (GPCRs) and TRPV (transient receptor potential vanilloid) channels are crucial for signal transduction in physiological processes...

N-type calcium channel (CaV2.2) protein contributes to neuronal excitability and overactivation in sympathetic ganglion (SG) following myocardial infarction (MI), thereby easily triggering cardiac rem...

Despite the prevalence of chronic pain, the approval of novel, non-opioid therapeutics has been slow. A major translational challenge in analgesic development is the difference in gene expression and ...

Researchers looked at 56 treatments for acute and chronic pain. Few of them were effective.

March 17, 2025In this episode of "3-Minute Mondays!" we're diving into the cutting-edge research happening at the Jensen Lab at NYU College of Dentistry. Wit...

A study in a mouse model of obesity and prediabetes demonstrates that recruitment of macrophages to nerves has a protective role in diet-induced peripheral neuropathy.

Painful diabetic neuropathy (PDN) is one of the most common complications of diabetes. Recent studies suggested that gut microbiota dysbiosis contributes to the development of PDN, but underlying…

e investigated how different SCS paradigms modulate the activation of NK1R+ neurons, by developing NK1R-Cre;GCaMP6s transgenic mice and using in vivo calcium imaging of superficial NK1R+ neurons under...

Confusion has ensued about the future of programs and research supporting people with disabilities as a result of President Trump’s executive order.

Chronic pain is a leading cause of disability, affecting more women than men. Different immune cells contribute to this sexual divergence, but the mec…