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Reposted by Maria Fernanda P Fialho

PAIN @painthejournal.bsky.social · 16/09/2026

Fialho et al. find that neuropilin-1 drives nerve growth factor-dependent sensitization in trigeminal nociceptors and oral cancer pain. Targeting neuropilin-1 blocks tumor-derived algogens, offering a safer, nonopioid therapeutic strategy #PAIN bit.ly/4wCwhzq

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Reposted by Maria Fernanda P Fialho

NYU Pain Research Center @nyupainresearch.bsky.social · 06/07/2026

NEW PRC PAPER 🚨: The Bunnett lab identified Neuropilin-1 (NRP1) as a key mediator of NGF signaling driving oral cancer pain. Targeting NRP1 disrupts NGF/TrkA signaling, reduces nociceptor sensitization, and alleviates pain without directly blocking NGF! buff.ly/NmyrTLy

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Reposted by Maria Fernanda P Fialho

Raquel Tonello @tonelloraquel.bsky.social · 23/06/2026

📣Excited to share our new preprint! We identify synaptic vesicle endocytosis in nociceptors as a key driver of ongoing pain, and show that LNP‑delivered CRISPR/dCas9 repression of this pathway produces durable analgesia across multiple pain models. www.biorxiv.org/content/10.6...

biorxiv.org

Targeting Synaptic Vesicle Endocytosis in Nociceptors Provides Sustained Pain Relief

Endocytosis replenishes synaptic vesicle (SV) pools that are required for persistent transmission of chronic pain signals within nociceptive spinal circuits. The nociceptor-specific contribution of SV...

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Reposted by Maria Fernanda P Fialho

NYU Pain Research Center @nyupainresearch.bsky.social · 28/05/2026

Amazing day so far at the PRC symposium! So much exciting science from our research community and awesome keynote speakers. @karapedsgastrodoc.bsky.social @jimr-1.bsky.social @sarahanajjar.bsky.social @tonelloraquel.bsky.social @elisadamo.bsky.social @pazduran.bsky.social @badrsokrat.bsky.social

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Reposted by Maria Fernanda P Fialho

Raquel Tonello @tonelloraquel.bsky.social · 13/11/2025

📢🔬Check out our latest study on the specific role of endocytic mediators in pain-related synaptic transmission, now out in PAIN. @mariafialho.bsky.social #PainResearch #Neuroscience #SynapticTransmission

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Maria Fernanda P Fialho @mariafialho.bsky.social · 11/06/2025

My first postdoc paper published 🎉🥳, and Raquel’s first as first senior author! Happy to be part of this! @nyupainresearch.bsky.social @tonelloraquel.bsky.social

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Reposted by Maria Fernanda P Fialho

Paz Duran @pazduran.bsky.social · 30/04/2025

Kicked off the USASP meeting last night with a mega pretzel at the NYU Pain Research Center dinner. Great start to a great week! #USASP2025 #PainResearch #NYUPRC #NetworkingAndPretzels

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Reposted by Maria Fernanda P Fialho

NYU Pain Research Center @nyupainresearch.bsky.social · 06/03/2025

@nyupainresearch.bsky.social Shoutout 📢 to The NYU Molecular Pathobiology for #hosting an amazing tea time #Mardi #Gras style! #Brazil #Zamba #Turnupthursdays #Happymardigras 🪅🎉🎊🪩💃🕺🏼 #NYUDental #newyorkuniversity

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Reposted by Maria Fernanda P Fialho

Journal of Clinical Investigation @jci.org · 20/02/2025

A non-opioid alternative in the treatment of chronic pain! Chloe J. Peach @tonelloraquel.bsky.social & team discover inhibition of Neuropilin-1 suppresses NGF-evoked pain in preclinical models: www.jci.org/articles/view/183873

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Reposted by Maria Fernanda P Fialho

NYU Pain Research Center @nyupainresearch.bsky.social · 19/02/2025

@tedpricethepainguy.bsky.social @utdpaincenter.bsky.social Great visit today from Dr. Ted Price! Thank you for wowing us with your team’s exciting data on human DRG tissue, very inspiring and insightful seminar! #painresearch #dorsalrootganglia #humanDRG #nyudental #nyuniversity #nyupainresearch

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