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Reposted by Raquel Tonello

PAIN @painthejournal.bsky.social · 16/09/2026

Fialho et al. find that neuropilin-1 drives nerve growth factor-dependent sensitization in trigeminal nociceptors and oral cancer pain. Targeting neuropilin-1 blocks tumor-derived algogens, offering a safer, nonopioid therapeutic strategy #PAIN bit.ly/4wCwhzq

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Reposted by Raquel Tonello

Ishmail Abdus-Saboor @ishmailsaboor.bsky.social · 17/09/2026

Thanks for having me, I had a great time! Wonderful community you have built with awesome science underway.

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Reposted by Raquel Tonello

NYU Pain Research Center @nyupainresearch.bsky.social · 21/07/2026

Great new review article from Ru-Rong Ji, Temugin Berta, and colleagues, on neuron-glia interactions in pain! Microglia, astrocytes, and satellite glial cells actively shape pain by driving neuroinflammation, sensitizing neurons, and remodeling pain circuits. journals.physiology.org/doi/full/10....

journals.physiology.org

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Reposted by Raquel Tonello

NYU Pain Research Center @nyupainresearch.bsky.social · 14/07/2026

NEW PRC PAPER 🚨: The Jensen lab discovered that disrupting synaptic vesicle recycling via AAK1, Dnm1, and Dnm3 targets chronic itch at its source. Amazing work @pazduran.bsky.social @tonelloraquel.bsky.social and the team! www.frontiersin.org/journals/mol...

frontiersin.org

Frontiers | The contribution of endocytic mediators to itch transmission

IntroductionChronic itch is a major burden, impacting the quality of life for one in four adults, and is closely associated with increased levels of anxiety,...

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Reposted by Raquel Tonello

NYU Pain Research Center @nyupainresearch.bsky.social · 06/07/2026

NEW PRC PAPER 🚨: The Bunnett lab identified Neuropilin-1 (NRP1) as a key mediator of NGF signaling driving oral cancer pain. Targeting NRP1 disrupts NGF/TrkA signaling, reduces nociceptor sensitization, and alleviates pain without directly blocking NGF! buff.ly/NmyrTLy

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Raquel Tonello @tonelloraquel.bsky.social · 23/06/2026

📣Excited to share our new preprint! We identify synaptic vesicle endocytosis in nociceptors as a key driver of ongoing pain, and show that LNP‑delivered CRISPR/dCas9 repression of this pathway produces durable analgesia across multiple pain models. www.biorxiv.org/content/10.6...

biorxiv.org

Targeting Synaptic Vesicle Endocytosis in Nociceptors Provides Sustained Pain Relief

Endocytosis replenishes synaptic vesicle (SV) pools that are required for persistent transmission of chronic pain signals within nociceptive spinal circuits. The nociceptor-specific contribution of SV...

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Reposted by Raquel Tonello

NYU Pain Research Center @nyupainresearch.bsky.social · 28/05/2026

Amazing day so far at the PRC symposium! So much exciting science from our research community and awesome keynote speakers. @karapedsgastrodoc.bsky.social @jimr-1.bsky.social @sarahanajjar.bsky.social @tonelloraquel.bsky.social @elisadamo.bsky.social @pazduran.bsky.social @badrsokrat.bsky.social

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Reposted by Raquel Tonello

NYU Pain Research Center @nyupainresearch.bsky.social · 27/05/2026

We are thrilled to bring together the NYU pain research community at our symposium tomorrow! Looking forward to a day of exciting science, connection, and collaboration.

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Raquel Tonello @tonelloraquel.bsky.social · 07/04/2026

Amazing opportunity to work with Dr. Gomez!

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Reposted by Raquel Tonello

NYU Pain Research Center @nyupainresearch.bsky.social · 16/03/2026

NEW PRC PAPER 🚨 This study led by @mariafialho.bsky.social from the Bunnett Lab reveals that tryptase from mast cells activates PAR2 on sensory neurons, sustaining painful symptoms induced by an aromatase inhibitor. buff.ly/lVAgUgO @tonelloraquel.bsky.social @karapedsgastrodoc.bsky.social

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Reposted by Raquel Tonello

NYU Pain Research Center @nyupainresearch.bsky.social · 13/03/2026

NEW PRC PREPRINT 🚨 The Jensen Lab presents a new therapeutic target for itch: Blocking AAK1 and Dynamin in GRP neurons reduces scratching without behavioral side effects. buff.ly/rpfcj90 @tonelloraquel.bsky.social @pazduran.bsky.social

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Reposted by Raquel Tonello

NYU Pain Research Center @nyupainresearch.bsky.social · 05/03/2026

We had the honor of hosting Prof Jose Moron-Concepcion from @washumedicine.bsky.social yesterday! He gave a fantastic seminar on novel therapeutic approaches to prevent pain-induced opioid escalation and fentanyl overdoses. @linyhung.bsky.social @tonelloraquel.bsky.social @elisadamo.bsky.social

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Raquel Tonello @tonelloraquel.bsky.social · 13/11/2025

📢🔬Check out our latest study on the specific role of endocytic mediators in pain-related synaptic transmission, now out in PAIN. @mariafialho.bsky.social #PainResearch #Neuroscience #SynapticTransmission

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Reposted by Raquel Tonello

NYU Pain Research Center @nyupainresearch.bsky.social · 11/11/2025

NYU Pain Research Center is expanding! 💥 Seeking brilliant minds (Assistant or Associate Professor, tenure track) to explore chronic pain mechanisms & therapies. Join our mission to transform pain research. Apply now! 🧠✨ #Research #AcademicJobs apply.interfolio.com/176454

apply.interfolio.com

Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio

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Reposted by Raquel Tonello

NYU Pain Research Center @nyupainresearch.bsky.social · 11/11/2025

🎉 Join us for the 1st NYC Area Pain Research Meet-Up! 🗓 Fri, Dec 5 | 3–6 PM 📍 NYU Pain Research Center, 433 1st Ave Don’t miss Dr. Steve Davidson’s keynote: “Humanizing Pain Neurobiology for Translational Gain” — plus great company & treats! See you there! 💫 #PainResearch #NYCScience #Neurobiology

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Raquel Tonello @tonelloraquel.bsky.social · 11/06/2025

Excited to share my first senior author paper in Pain! 🎉 We identify Synaptojanin 1 & Endophilin A1 as key endocytic mediators of nociception. Silencing them blocks spinal synaptic transmission and relieves pain in cancer & postoperative models, without affecting normal behavior. buff.ly/caKMGY3

buff.ly

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Reposted by Raquel Tonello

NYU Pain Research Center @nyupainresearch.bsky.social · 10/04/2025

PRC PRIMED! Thank you to @rachelepol.bsky.social for presenting Nanomedicine for Pain: Towards translation through advanced materials, manufacturing and in vitro strategies! Huge round of applause 👏to @linyhung.bsky.social & @tonelloraquel.bsky.social for being amazing hosts! #PinkertonLab #RachelP

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Reposted by Raquel Tonello

NYU Pain Research Center @nyupainresearch.bsky.social · 12/03/2025

PRC PRIMED! #First event of the #year featuring a talk by #Dr. Kehinde Mary Taiwo, a Postdoctoral Fellow in #Dr. Candie Paulsen's lab at #Yale #University! @nyupainresearch.bsky.social #NYUDentistry #NewYorkUniversity

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Reposted by Raquel Tonello

Journal of Clinical Investigation @jci.org · 20/02/2025

A non-opioid alternative in the treatment of chronic pain! Chloe J. Peach @tonelloraquel.bsky.social & team discover inhibition of Neuropilin-1 suppresses NGF-evoked pain in preclinical models: www.jci.org/articles/view/183873

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Reposted by Raquel Tonello

NYU Pain Research Center @nyupainresearch.bsky.social · 19/02/2025

@tedpricethepainguy.bsky.social @utdpaincenter.bsky.social Great visit today from Dr. Ted Price! Thank you for wowing us with your team’s exciting data on human DRG tissue, very inspiring and insightful seminar! #painresearch #dorsalrootganglia #humanDRG #nyudental #nyuniversity #nyupainresearch

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Raquel Tonello @tonelloraquel.bsky.social · 18/12/2024

I'm excited to share our groundbreaking findings on Neuripilin-1 and its role in NGF/TrkA pain signaling.

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Reposted by Raquel Tonello

MargolisLab @margolislabnyu.bsky.social · 12/12/2024

Congrats to the whole team for the paper published in Gastroenterology this week! 🎉🧠🌟 #gutserotonin #depression #anxiety #antidepressants @tonelloraquel.bsky.social @danielxjuarez.bsky.social @karapedsgastrodoc.bsky.social @sarahanajjar.bsky.social 👉 www.gastrojournal.org/article/S001...

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