iiinova — where your digital self keeps evolving

Reposted by Paresh Malhotra

NIHR PRU in Dementia and Neurodegeneration Exeter @denpruexeter.bsky.social · 29/09/2026

Do you live with #dementia or a #neurological condition? Do you care for someone with such? Please fill out our survey about using NHS digital tools (eConsults, health apps) and services (remote appts) so that we can improve the experience! 📲👨‍💻🧠 forms.cloud.microsoft/e/9FhTWcVRDF

forms.cloud.microsoft

Microsoft Forms

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Dementia Researcher @dementiaresearcher.bsky.social · 23/09/2026

Research Associate role at Imperial testing whether TSPO targeting can improve cerebrovascular function and brain activity in early Alzheimer’s disease. Closing date: 4th October www.dementiaresearcher.nihr.ac.uk/job/research...

dementiaresearcher.nihr.ac.uk

Research Associate: Alzheimer’s and Cerebrovascular Function

Imperial seeks a Research Associate to test whether TSPO targeting improves cerebrovascular function and brain activity in early Alzheimer’s disease.

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Reposted by Paresh Malhotra

UCL Innovative Clinical Trials Unit @innovative-ctu.bsky.social · 17/09/2026

🚨 Exciting interim results from the OCTOPUS trial! Alpha-lipoic acid shows early promise in slowing progression of MS and will move to the next stage of the trial. A milestone for innovative #MAMS trials in MS. 🔗 Read more: www.innovative-ctu.ucl.ac.uk/news/news-st... @mssocietyuk.bsky.social

innovative-ctu.ucl.ac.uk

Alpha-lipoic acid shows ‘early promise’ to treat progressive multiple sclerosis | UCL Innovative Clinical Trials Unit

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London Review of Books @lrb.co.uk · 05/08/2026

Tell me about a complicated magazine. Try the 𝘓𝘰𝘯𝘥𝘰𝘯 𝘙𝘦𝘷𝘪𝘦𝘸 𝘰𝘧 𝘉𝘰𝘰𝘬𝘴 for three months, in print and online, for just £6. subscription.lrb.co.uk/offers/social

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Research at ARUK @alzheimersresearchuk.org · 21/07/2026

AD-SMART is inviting proposals for innovative, validated digital outcome measures to support a UK-wide platform trial evaluating Alzheimer’s disease therapeutics. Find out more and apply by 30 Aug: www.innovative-ctu.ucl.ac.uk/studies/all-...

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London Review of Books @lrb.co.uk · 16/07/2026

so how’s it going with the Parkinson’s? you say and I start to say every moment bleeding to death around me but the therapist cautioned me yesterday don’t say dread call it discomfort you’re not in danger you’re uncomfortable ‘Smile’, a poem by Anne Carson. www.lrb.co.uk/the-paper/v4...

lrb.co.uk

Anne Carson · Poem: ‘Smile’

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Paresh Malhotra @pareshmalhotra.bsky.social · 16/07/2026

Guy on train reading Slaughterhouse 5 just had his coffee knocked out of his hand. #Soitgoes

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Alzheimer's Association @alzassociation.bsky.social · 15/07/2026

Join us tomorrow, July 16 at #AAICForAll in London, UK! Register for this no-cost, single-day event to get updates & insights from the world’s largest meeting on dementia science. Learn more: alz.org/aaic-for-all

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NEJM.org @nejm.org · 08/07/2026

Among patients with newly diagnosed relapsing multiple sclerosis, rituximab was noninferior to ocrelizumab in preventing new or enlarging lesions on MRI. The risk of serious adverse events was similar in the two groups. Full OVERLORD-MS trial results and Research Summary: nej.md/3QJuaep

This image is from a Research Summary published in the New England Journal of Medicine, comparing rituximab and ocrelizumab for relapsing multiple sclerosis. It features participant details: 216 adults, mean age 37, with a gender distribution of 70% men and 30% women; 132 received rituximab while 84 received ocrelizumab. Illustrations depict a conceptual representation of relapsing multiple sclerosis. A note encourages further reading at NEJM.org.

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Eric Topol @erictopol.bsky.social · 04/07/2026

On our 250th birthday, celebrating the contribution of immigrants and international collaboration —46% of people with doctoral-level degrees working in US science and engineering fields are foreign-born

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davidweinshenker.bsky.social @davidweinshenker.bsky.social · 22/06/2026

The UK National Institute for Health and Care Research developed a systematic drug prioritization pipeline to identify repurposed drug candidates for inclusion in a planned platform trial for clinical AD. The norepinephrine reuptake inhibitor atomoxetine came in #1. pubmed.ncbi.nlm.nih.gov/42186115/

pubmed.ncbi.nlm.nih.gov

Checking your browser - reCAPTCHA

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Auschwitz Memorial @auschwitzmemorial.bsky.social · 12/06/2026

12 June 1929 | A German Jewish girl, Anne Frank, was born in Frankfurt. In 1942, on her 13th birthday, she received an empty diary. She perished in Bergen-Belsen concentration camp in 1945. 'Human greatness does not lie in wealth or power, but in character & goodness.' (A.Frank)

Anne Frank seated at a desk with an open book and a pen, looking directly at the camera, with a bottle of ink by her side.

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Janine Gibson @janinegibson.ft.com · 12/06/2026

Here is a gift link to Simon Schama's appreciation of David Hockney's life and art which we ran last year. It's an amazing piece and contains, as you might imagine, some spectacular pictures including an absolute corker of Hackney with Lucian Freud as.ft.com/r/f1473f70-0...

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Paresh Malhotra @pareshmalhotra.bsky.social · 12/06/2026

Work led by Mike David looking at #arousal and #synchrony in clinical #alzheimers disease through #pupillometry #fmri and #neuromelanin imaging of the #locuscoeruleus, the brain’s key #noradrenaline nucleus. el. Hopefully relevant for treatment. alz-journals.onlinelibrary.wiley.com/share/AARWJ2...

alz-journals.onlinelibrary.wiley.com

Cortical synchrony is reduced in Alzheimer's disease and relates to arousal state

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Lewis Goodall @lewisgoodall.com · 02/06/2026

Henry Nowak’s father’s words outside court, who is probably the person we most need to hear from today.

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Paresh Malhotra @pareshmalhotra.bsky.social · 29/05/2026

Really happy to share the paper describing drug repurposing pipeline for an upcoming platform trial in clinical #Alzheimers disease with candidate selection through multidisciplinary international panel chaired by @suzanne-reeves.bsky.social. alz-journals.onlinelibrary.wiley.com/share/SIZN3I...

alz-journals.onlinelibrary.wiley.com

Repurposed drug prioritization pipeline for a multi‐arm platform trial in clinical Alzheimer's disease

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UK Dementia Research Institute @ukdri.ac.uk · 23/05/2026

Our researchers at the UK DRI at Edinburgh are featured on the BBC today, highlighting how AI is transforming the search for treatments for neurodegenerative conditions 👏 Thank you to Steve, who generously shared his story and why research gives him hope 💙 www.bbc.co.uk/news/article...

bbc.co.uk

AI used to speed up search for motor neurone disease drugs

Researchers hope the work will help identify affordable, effective drugs to treat conditions like MND.

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Jess Cardin @jess-cardin.bsky.social · 13/05/2026

Do brain circuits really sit in a 'soup' of neuromodulators? Are neurons like soggy bits of bread soaked in signaling factors? Is the whole brain just squelching around in one big pool of warm modulators?

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brainresilience.bsky.social @brainresilience.bsky.social · 17/04/2026

Stanford neurologists Michael Greicius and Victor Henderson explain what science knows about why women develop Alzheimer’s disease at higher rates than men—and the many things science doesn’t yet know. Learn more: med.stanford.edu/news/insight...

Michael Greicius, Stanford Neurologist, Knight Initiative for Brain Resilience Steering Committee member, and founding director of the Stanford Memory Disorders Center.

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Gail Drakes @gaildrakes.bsky.social · 02/05/2026

I teach this in my IP law class b/c when asked in an interview who owned the patent, Salk replied: "Well, the people, I would say. There is no patent. Could you patent the sun?" He looked for vaccine solutions his entire life…including a quest for a vaccine to prevent HIV from becoming AIDS.

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Mayor of London, Sadiq Khan @london.gov.uk · 26/04/2026

London is the fastest city in the world. Congratulations to Sebastian Sawe and Tigst Assefa for their incredible achievements, breaking both the men's and women's world records.

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Evan Gordon @gordonneuro.bsky.social · 22/04/2026

I always assumed that brain function had to line up with cytoarchitectonics. It turns out I was wrong. Human cortex, especially PFC, is tiled by chains of functional patches that subdivide and interlink architectonic areas into parallel processing streams. www.biorxiv.org/content/10.6...

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James Catterson @scotsfriction.bsky.social · 19/11/2024

🧠Sharing this Starter Pack again as the list has now reached 80 people! A great mix of Profs/PIs/Post-docs/PhDs/Technicians. Please re-post so it can reach a wider audience as I'm sure there are more of us out there ☺️🦋 go.bsky.app/S6FfsTp

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Department of Brain Sciences @imperialbrains.bsky.social · 10/04/2026

🧠 Discover the Landmark Project @imperialcollegeldn.bsky.social, profiling over 400 human brain donations to develop technologies for predicting disease progression and drug response in Parkinson's More 👉 www.imperial.ac.uk/news/256397/... #WorldParkinsonsDay

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UK Dementia Research Institute @ukdri.ac.uk · 07/04/2026

A selection of participants from the REACT study at Imperial College London are attending initial clinics via Inuvi for tests that will make them 'trial-ready'. Funded by the Medical Research Council, the initiative supports the Dame Barbara Windsor Dementia Goals programme.

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David Collard @davidcollard.bsky.social · 06/04/2026

The Bluesky account for the Barbellion Prize has changed to @barbellionprize.bsky.social Do please follow! The submission window for authors and publisher is open from now until 1st September, and there are full details on the new website barbellionprize.org

barbellionprize.org

The Barbellion Prize | A prize recognising literary representation of chronically disabled lives.

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Dementia Researcher @dementiaresearcher.bsky.social · 04/04/2026

The UK DRI at King’s College London is hiring a Research Associate to study ALS using multiomics, stem cell models and bioinformatics to uncover early disease signatures. Closing date: 28th April www.dementiaresearcher.nihr.ac.uk/job/research...

dementiaresearcher.nihr.ac.uk

Research Associate: Molecular signatures of ALS pathology

UK DRI at King’s College London seeks a Research Associate to study ALS using multiomics, stem cell models & bioinformatics to uncover early disease mechanisms

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Paresh Malhotra @pareshmalhotra.bsky.social · 03/04/2026

Am reading the brilliant #SuddenlySomethingClicked by Walter Murch. A great book for anyone who likes films but so insightful about so many aspects of working and thinking to make or do ANYthing. Fantastic.

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Paresh Malhotra @pareshmalhotra.bsky.social · 03/04/2026

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Reposted by Paresh Malhotra

Research at ARUK @alzheimersresearchuk.org · 31/03/2026

Stronger funding applications start with understanding the process. Apply to observe our Research Committee as they review early career fellowship and scholarship applications: www.alzheimersresearchuk.org/research/for...

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Paresh Malhotra @pareshmalhotra.bsky.social · 24/03/2026

I held off reading this by @matthewcobb.bsky.social because it might be #toomuchlikethedayjob for way too long. Fantastic - really enjoyable and often v funny. Strongly recommend!

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Helen Barron @helencbarron.bsky.social · 20/03/2026

*** New paper from the lab in Nature Comms !! *** “Noradrenaline causes a spread of association in the hippocampal cognitive map” by the amazing @reneecabbage.bsky.social in collab. w labs of Jill O’Reilly, Will Clarke, and modeling from Prakriti Parthasarathy and @tpvogels.bsky.social, see below!

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Axel Montagne @axelmontagne.bsky.social · 06/03/2026

🚨 PhD Programme – Vascular Dementia Research New 4-year PhD funded by BHF & UK DRI on vascular mechanisms in dementia. Training across UCL, Oxford, Leicester & Edinburgh with lab rotations. 📅 Deadline: 14 April 🎓 Start: Sept 2026 Apply: CV + statement + 2 refs → neurophd@ucl.ac.uk Please share!

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Paresh Malhotra @pareshmalhotra.bsky.social · 01/03/2026

Preparing a presentation and couldn’t work out why i kept abbreviating ‘Alzheimer’s & Dementia’ to ‘Alz & Dec’…

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Ben Goldacre @bengoldacre.bsky.social · 23/02/2026

OpenSAFELY is open from today! Huge thanks to all who supported this vast collaboration: whole population GP data; in a productive platform; innovative privacy protections; unprecedented support from professions, privacy campaigners; &c Now it's over to users! www.bennett.ox.ac.uk/blog/2026/02...

bennett.ox.ac.uk

OpenSAFELY news: you can apply to do non-COVID research, from today! | Bennett Institute for Applied Data Science

We are delighted to announce that - from today - you can submit applications to the OpenSAFELY service for non-COVID-19 studies.

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Colin Gorrie @colingorrie.bsky.social · 18/02/2026

Written English has barely changed in 300 years. If you can read Harry Potter, you can read Robinson Crusoe (1719).

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Caswell Barry @caswell.bsky.social · 03/02/2026

Also tagging the first author. @shipleysj.bsky.social

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Selina Wray @selinawray.bsky.social · 01/02/2026

The pause of response mode funding will have a huge impact on ECRs who are not yet fellowship ready.When researchers leave academia they rarely return. Clarity on when RM will reopen is urgently needed & transitions to the new model need to avoid investment gaps that disproportionally affect ECRs

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Dementia Researcher @dementiaresearcher.bsky.social · 22/01/2026

Clinical Research Manager role at Cure Parkinsons providing strategic leadership across clinical trial development and treatment selection. www.dementiaresearcher.nihr.ac.uk/job/clinical...

dementiaresearcher.nihr.ac.uk

Clinical Research Manager - DEMENTIA RESEARCHER

Cure Parkinsons seeks a Clinical Research Manager to lead clinical development and support disease modifying trials in Parkinsons research.

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