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Nick Ilott

@nickilott.bsky.social
744 followers 571 following 50 posts

Scientist studying microbiome-host interactions in primary sclerosing cholangitis at the University of Oxford. #microbiome #scRNAseq #bioinformatics #metagenomics #metabolomics #transcriptomics I also like drawing: www.instagram.com/ilottnick21

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Reposted by Nick Ilott
Rachel Anscombe @rachelanscombe.bsky.social · 23/09/2026
Thrilled to share that I won an award for best presentation at the annual Kennedy Institute Student Symposium (#KISS2026) last week! It was great to present my PhD story so far and to hear all about everyone’s exciting work! One more year of the PhD and one more KISS to go🥳🧠 @kiroxford.bsky.social
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The Powrie Lab @powrielab.bsky.social · 23/09/2026
The annual Kennedy Institute Student Symposium (#KISS2026) was a huge success last week! Special shoutouts go to the PhD students in our lab - Catherine (1st year) & Rachel (3rd year) for being a runner-up and winner in their respective PhD cohort presentations🥳👩‍🔬💪 @kiroxford.bsky.social
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David Bikard @dbikard.bsky.social · 21/09/2026
New paper from the lab, out in Nature Microbiology. We ran CRISPRi screens to ask what genes E. coli needs in order to live in a gut and what this can tell us about the gut environment itself. doi.org/10.1038/s41564-026-02471-8
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The Powrie Lab @powrielab.bsky.social · 20/07/2026
Last week several lab members were in Montreal for #ICMI2026! We had a fantastic time listening to the amazing talks about the lastest work in the mucosal immunology field & were thrilled to share our work via some great posters and talks!🇨🇦👩‍🔬 @societymucosalimm.bsky.social @kiroxford.bsky.social
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The Powrie Lab @powrielab.bsky.social · 10/07/2026
In case you missed it‼️ The wonderful @nickilott.bsky.social from @oxmicrobiome.bsky.social & our lab made an appearance on BBC Radio 4's Sliced Bread last week!📻 The episode gives a great run down on gut microbiome testing kits🦠🧑‍🔬 Catch up on the episode here! www.bbc.co.uk/sounds/play/...
bbc.co.uk
Sliced Bread - Sliced Bread - Series 17 - Gut Microbiome Tests - BBC Sounds
Can a test tell you what's living inside your gut - and what to do about it?
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Britt Koskella @bkoskella.bsky.social · 09/07/2026
Postdocs and early career folks - this is a truly wonderful opportunity to spend time in Berlin, gain time to think, and expand your network! call.wiko-berlin.de/procedure/65...
call.wiko-berlin.de
Wiko Application Platform
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Michael Hendricks 🇨🇦 @michaelhendricks.bsky.social · 09/07/2026
You also don't have to do an editor's job of deciding if a paper "fits" or is "impactful enough" for their journal, because you're a scientist and not a marketing agent for the publisher.
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Timothy O'Leary @timothyoleary.bsky.social · 09/07/2026
Dear peer reviewers everywhere: sometimes we feel pressure to find issues with a submission as a demonstration of diligence. But we have to recognise this is a mistake: picking random and sometimes incoherent holes in research add confusion, generates unnecessary work and encourages defensive
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Nick Ilott @nickilott.bsky.social · 08/07/2026
So tired! thank you for making life less shit
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Nick Ilott @nickilott.bsky.social · 08/07/2026
It’s wild how we have gone from ‘Hmm I wonder if the authors actually read the paper’ to ‘Hmm does this paper even exist’ when reviewing manuscripts #AI #scientificIntegrity
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Josie Bryant @josiebryant.bsky.social · 08/07/2026
Very proud of this preprint out of my lab, our first (of hopefully many) host-microbe spatial transcriptomics paper. www.biorxiv.org/content/10.6... Amazing insights into P. aeruginosa biology and chronic airway disease @cysticfibrosis.org.uk @sangerinstitute.bsky.social @asthmaandlung.org.uk
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Science Magazine @science.org · 08/07/2026
A new analysis demonstrates how kidney-infiltrating T cells might contribute to kidney injury in patients with lupus, phage therapy switches off malicious E. coli to calm colitis in Crohn's disease, and more this week in #ScienceTranslationalMedicine. scim.ag/4aDHuYt
Shown is a transmission electron micrograph of a bacteriophage (orange) on an Escherichia coli bacterium (blue). Credit: Biozentrum, University of Basel/Science Source
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NDORMS, University of Oxford @ndorms.bsky.social · 06/07/2026
Can a gut microbiome testing kit really tell you what's living in your gut – and what you should eat? 🦠 🌽 Dr @nickilott.bsky.social from the Oxford Centre for Microbiome Studies joined BBC Radio 4's Sliced Bread to separate the evidence from the marketing. Listen at: www.bbc.co.uk/sounds/play/...
bbc.co.uk
Sliced Bread - Sliced Bread - Series 17 - Gut Microbiome Tests - BBC Sounds
Can a test tell you what's living inside your gut - and what to do about it?
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Reposted by Nick Ilott
Kennedy Institute of Rheumatology @kiroxford.bsky.social · 03/07/2026
Can microbiome tests tell you what's living in your gut? 🦠 Can they provide diets personalised to your resident microbes? 🥑 Dr Nick Ilott joined presenter Greg Foot and Dr Fred Warren on the Sliced Bread Podcast to discuss! Listen now 🎧 www.bbc.co.uk/sounds/play/... @nickilott.bsky.social
bbc.co.uk
Sliced Bread - Sliced Bread - Series 17 - Gut Microbiome Tests - BBC Sounds
Can a test tell you what's living inside your gut - and what to do about it?
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Nick Ilott @nickilott.bsky.social · 30/06/2026
Tune in this Thursday 2nd July to #BBCRadio4 #SlicedBread to hear our discussion on at-home microbiome tests for personalised diet plans - interested to hear what made the final edit 😬
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The Dunn School, Oxford @dunnschool.bsky.social · 30/06/2026
We are always excited by the success of members of @dunnschool.bsky.social! Huge congratulations to Profs Emma Slack @mucosalimmunology.bsky.social and Kevin Foster on their election as members of @embo.org Both are microbiome leaders – and both are stars www.path.ox.ac.uk/news-article...
path.ox.ac.uk
Emma Slack and Kevin Foster elected members of EMBO - Dunn School
Both researchers are leaders in the rapidly growing field of the human gut microbiome.
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Matthew Freeman @mjafreeman.bsky.social · 30/06/2026
Great news! Congratulations to Emma Slack (@mucosalimmunology.bsky.social) and Kevin Foster for this very well deserved honour www.path.ox.ac.uk/news-article...
path.ox.ac.uk
Emma Slack and Kevin Foster elected members of EMBO - Dunn School
Both researchers are leaders in the rapidly growing field of the human gut microbiome.
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Cameron Thrash @jcamthrash.bsky.social · 29/06/2026
CarveMe-GutMicrobes: Automated Metabolic Model Reconstruction for Gut Microbial Species and Communities www.biorxiv.org/content/10.6... #jcampubs
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Mayor of London, Sadiq Khan @london.gov.uk · 29/06/2026
10 years ago, the air outside Aldgate School didn’t meet legal limits. Children were breathing polluted air every day. I made it my mission to change that. Here’s the difference our bold policies have made ⬇️
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PSC Support @pscsupport.bsky.social · 28/06/2026
Small seed grants lead to massive discoveries! Dr Sun used preliminary data from a study funded by #PSCSupport to secure a prestigious MRC Clinical Research Training Fellowship. He’s now diving deep into genetic drivers of primary sclerosing cholangitis. pscsupport.org.uk/research-wev...
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Nick Ilott @nickilott.bsky.social · 27/06/2026
Worth waiting for! Happy World Microbiome Day everyone!
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PSC Support @pscsupport.bsky.social · 27/06/2026
Kieron Dyer joined Sky Sports to talk about why he's backing @PSCSupportUK for @BigGive's #SmallCharityWeek! Thanks to our incredible donors we've reached our goal and accessed all our match funding 🎉 but you can still donate (and boost your donation by 25% with Gift Aid!)🔗 youtu.be/ksvI6Ud3pfw
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Kieron Dyer Speaks to Sky Sports About Rare Autoimmune Liver Disease (PSC) for Small Charity Week
England footballing legend and liver transplant recipient Kieron Dyer joined Sky Sport to speak passionately about his personal journey with Primary Sclerosing Cholangitis (PSC) and to champion our…
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Nature Biotechnology @natbiotech.nature.com · 26/06/2026
Spatially resolved profiling of extracellular vesicles in tissues with Spatial-EV-seq www.nature.com/articles/s41...
nature.com
Spatially resolved profiling of extracellular vesicles in tissues with Spatial-EV-seq - Nature Biotechnology
Spatial-EV-seq reveals spatial patterns of extracellular vesicles in tissues.
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Nature Microbiology @natmicrobiol.nature.com · 26/06/2026
Out Now! Bacteroides fragilis toxin promotes gall bladder cancer in mice #MicroSky
go.nature.com
Bacteroides fragilis toxin promotes gall bladder cancer in mice
Nature Microbiology, Published online: 25 June 2026; doi:10.1038/s41564-026-02404-5Binding between bacterial membrane-bound lytic murein transglycosylase D (MltD) and host transmembrane serine protease 13 (TMPRSS13) potentiates the tumorigenic effects of Bacteroides fragilis toxin through JAK2–STAT3 signalling and myeloid-derived suppressor cell recruitment in gall bladder cancer.
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PSC Support @pscsupport.bsky.social · 26/06/2026
Football legend & PSC transplant patient Kieron Dyer went on @tSHandJ to back our @biggive #SmallCharityWeek campaign! 😭❤️ Having his voice championing our rare disease community means everything. Shortly after this interview WE HIT OUR TARGET! (1/2) #LetsBeatPSC
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Oxford Centre for Microbiome Studies @oxmicrobiome.bsky.social · 26/06/2026
#WorldMicrobiomeDay 11 countdown 💩 Today, Rahul from OCMS answers questions about the #gutmicrobiome and #mentalwellbeing. 🧠 This is our final FAQ video before World Microbiome Day — thanks for following along and stay tuned for the finale 📽️ .
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The gut microbiome and mental wellbeing 🧠
YouTube video by NDORMS
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The Powrie Lab @powrielab.bsky.social · 25/06/2026
Super exciting work from our close collaborators in the Uhlig group highlighting a link between the recently discovered IL-10 autoantibodies in IBD patients and HLA-DRB1*01:03! Congratulations to everyone involved - go check out the paper here!🎉 www.nejm.org/doi/full/10.... @kiroxford.bsky.social
nejm.org
Interleukin-10 Autoantibodies and HLA-DRB1*01:03 in Inflammatory Bowel Disease | NEJM
Neutralizing autoantibodies against interleukin-10 can result in a phenocopy of monogenic defects of interleukin-10 signaling in children and may be associated with inflammatory bowel disease (IBD)...
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Oxford Centre for Microbiome Studies @oxmicrobiome.bsky.social · 25/06/2026
#WorldMicrobiomeDay 11 countdown 💩 Today, Ffion from Powrie lab discusses: 🧼 "Are cleaning products harmful to our gut microbiome?" 👨🏼‍🔬 Follow along as Oxford scientists answer your questions about the human microbiome — one short video each day until World Microbiome Day. ⚠️ see comments 🪥 & 🐾
youtu.be
Are cleaning products harmful to our gut microbiome? 🧼
YouTube video by NDORMS
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anna brogan @apbrogan.bsky.social · 23/06/2026
Another chapter of my thesis is out! We asked whether we could pair proteome-wide AlphaFold screening with Tn-seq to identify biologically relevant protein-protein interactions. We identify ClcR (formerly YerH) as a component of the Rod complex in Gram-positive bacteria. www.pnas.org/doi/10.1073/...
pnas.org
A broadly conserved gram-positive lipoprotein regulates cell elongation | PNAS
The cell wall peptidoglycan (PG) protects virtually all bacteria from osmotic lysis and specifies cell shape. Synthesis of this exoskeleton is carr...
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Oxford Centre for Microbiome Studies @oxmicrobiome.bsky.social · 24/06/2026
#WorldMicrobiomeDay 9️⃣ countdown 💩 Today, Uzma from OCMS answers: 🪥 "Is the #oralmicrobiome linked to #Alzheimer's disease" 👨🏼‍🔬 Follow along as Oxford scientists answer your questions about the human microbiome — one short video each day until World Microbiome Day. @uzmakhan.bsky.social
youtu.be
Is oral health linked to Alzheimer's disease? 🦷
YouTube video by NDORMS
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Oxford Centre for Microbiome Studies @oxmicrobiome.bsky.social · 23/06/2026
#WorldMicrobiomeDay 8️⃣ countdown 💩 Today, Isaac from OCMS answers your questions about about how we study the #gutmicrobiome 🦠 👨🏼‍🔬 Follow along as Oxford scientists answer your questions about the human microbiome — one short video each day until World Microbiome Day. @isaac-dennis.bsky.social
youtu.be
How do you research the gut microbiome? 🔬
YouTube video by NDORMS
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NDORMS, University of Oxford @ndorms.bsky.social · 24/06/2026
As we approach World Microbiome Day, the team at the Oxford Centre for Microbiome Studies are answering your questions about all things gut bacteria, poo, diet, probiotics, viruses, the immune system, health, disease, research methods and more! 🦠🍏🔬💩
bsky.app
Oxford Centre for Microbiome Studies (@oxmicrobiome.bsky.social)
Driving microbiome insights. Original research and supporting collaborations. https://www.kennedy.ox.ac.uk/ocms https://www.linkedin.com/company/oxmicrobiome University of Oxford
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Sean Gibbons 🦠💩 @gibbological.bsky.social · 22/06/2026
Interesting new preprint on using MICOM to predict responders/non-responders to FMTs 👇 "Metagenome-scale Modeling to Assess Microbiome Metabolic Complementarity for Precision Microbiota Transplantation Therapies" www.biorxiv.org/content/10.6...
biorxiv.org
Metagenome-scale Modeling to Assess Microbiome Metabolic Complementarity for Precision Microbiota Transplantation Therapies
Fecal microbiota transplantation (FMT) holds therapeutic promise beyond recurrent Clostridioides difficile infection, but clinical outcomes remain unpredictable, in part because existing computational...
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Oxford Centre for Microbiome Studies @oxmicrobiome.bsky.social · 22/06/2026
#WorldMicrobiomeDay 7️⃣ countdown 💩 Today, Chik On from OCMS answers: 🦠 “Can #fermentedfoods change your microbiome?” 👩🏼‍🔬Follow along as Oxford scientists answer your questions about the human microbiome — one short video each day until World Microbiome Day. Chik On Choy is the OCMS Project Manager
youtu.be
Can fermented food change your microbiome? 🧀
YouTube video by NDORMS
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Oxford Centre for Microbiome Studies @oxmicrobiome.bsky.social · 21/06/2026
#WorldMicrobiomeDay 6️⃣ countdown 💩 Today, OCMS scientist Holly answers: 🦠 “Why do we #fart?” Follow along as Oxford scientists answer your questions about the human microbiome — one short video each day until World Microbiome Day. youtu.be/JLZlqarEjlQ?... @hollyroach.bsky.social
youtu.be
Why do some people fart more than others? 💩
YouTube video by NDORMS
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Kimberly Kline 🏔 @kimingeneva.bsky.social · 19/06/2026
We've been learning a lot about how Enterococcus faecalis interacts with neutrophils lately. In our latest preprint, @harisantypas.bsky.social describes how lactic acid from E. faecalis dampens neutrophil metabolism leading to NETosis and phagoytosis suppression. #microsky
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Oxford Centre for Microbiome Studies @oxmicrobiome.bsky.social · 20/06/2026
#WorldMicrobiomeDay 5️⃣ countdown 💩 Today, OCMS scientist Holly answers: 🦠 “What is a healthy #gutmicrobiome?” Follow along as Oxford scientists answer your questions about the human microbiome — one short video each day until World Microbiome Day. youtu.be/lsPkZf-nS0M?... @hollyroach.bsky.social
youtu.be
What is a healthy microbiome? 🥦
YouTube video by NDORMS
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Oxford Centre for Microbiome Studies @oxmicrobiome.bsky.social · 19/06/2026
#WorldMicrobiomeDay 4️⃣ countdown 💩 Today, @nickilott.bsky.social answers: 🦠 “How do our environment, microplastics and pollution affect our #gutmicrobiome?” Follow along as Oxford scientists answer your questions about the human microbiome — one short video each day until World Microbiome Day.
youtu.be
The microbiome and the environment 🌳
YouTube video by NDORMS
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Nick Ilott @nickilott.bsky.social · 19/06/2026
Bacteria are awesome bioindicators!
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Noah Fierer @noahfierer.bsky.social · 18/06/2026
Ever wanted to use metagenomic data to infer oxygen levels (or the oxygen preferences of whole bacterial communities)? We have the tool for you: journals.asm.org/eprint/9GUIR...
journals.asm.org
Predicting oxygen levels in microbial habitats using a metagenome-based approach | mSystems
Oxygen is one of the most important environmental variables affecting microbial activity and composition, but is often difficult to measure in situ. We developed a tool, OxyMetaG, that leverages diffe...
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Oxford Centre for Microbiome Studies @oxmicrobiome.bsky.social · 18/06/2026
#WorldMicrobiomeDay 3️⃣ countdown 💩 Today, Kate and Holly from OCMS answer: 🦠 “How do diet and fibre affect the #microbiome?” 👩🏻‍🔬👩🏼‍🔬Follow along as Oxford scientists answer your questions about the human microbiome — one short video each day until World Microbiome Day.
youtu.be
The microbiome and diet 🌽
YouTube video by NDORMS
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Mucosal Immunology @mucosalimmunol.bsky.social · 17/06/2026
Indoor rewilding of laboratory mice recalibrates pulmonary mucosal immunity and mechanics www.mucosalimmunology.org/article/S193...
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PSC Support @pscsupport.bsky.social · 17/06/2026
Artificial Bile Ducts Update! We caught up with Dr Sampaziotis and Dr Brevini who are working on developing artificial bile ducts for PSC and presented impressive progress on their work at the #EASL Congress last month. youtu.be/tOtAF-QEKyk More EASL updates ➡️ pscsupport.org.uk/may-2026-res...
youtu.be
Artificial Bile Ducts Update with Dr Fotios Sampaziotis and Dr Teresa Brevini at EASL 2026
Remember Dr Fotios Sampaziotis and Dr Teresa Brevini  from Cambridge who are working on developing artificial bile ducts for PSC? We caught up with them just after they had presented impressive…
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The Powrie Lab @powrielab.bsky.social · 17/06/2026
Throwing it back to Day 2 of KIPS, with more excellent postdoc talks and a great keynote from Kevin Foster! It was also announced that Ffion won the award for the best long talk!🥳 Thanks to the fantastic postdoc committee for organising two great days of science!👩‍🔬👨‍🔬 @kiroxford.bsky.social
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Oxford Centre for Microbiome Studies @oxmicrobiome.bsky.social · 17/06/2026
#WorldMicrobiomeDay 2️⃣ countdown 💩 Today, Holly from OCMS answers: 🦠 “Where does our #microbiome come from?” Follow along as Oxford scientists answer your questions about the human microbiome — one short video each day until World Microbiome Day. @hollyroach.bsky.social
youtu.be
Where do our gut microbes come from? 🦠
YouTube video by NDORMS
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Oxford Centre for Microbiome Studies @oxmicrobiome.bsky.social · 16/06/2026
#WorldMicrobiomeDay1️⃣ countdown 💩 Today, Kate from OCMS answers: 🦠 “What is a #microbiome?” 👩🏻‍🔬Follow along as Oxford scientists answer your questions about the human microbiome — one short video each day until World Microbiome Day. @katecoldwell.bsky.social youtu.be/Fqfq-u6Yxic
youtu.be
An introduction to the microbiome
YouTube video by NDORMS
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Nick Ilott @nickilott.bsky.social · 15/06/2026
Was great to chat to Mark at @pscsupport.bsky.social at #EASL2026 about some of our work in the small intestine in PSC youtu.be/VrLaan3P9-g?...
youtu.be
Dr Ilott sums up his latest results about bile flows influence on the small intestine
YouTube video by PSC Support
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Oxford Centre for Microbiome Studies @oxmicrobiome.bsky.social · 15/06/2026
📽️ Excited to be filming with @ndorms.bsky.social for our #WorldMicrobiomeDay event. Starring 🦠 💩 👩🏼‍🔬 🧑🏻‍🔬
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Plague Poems @plaguepoems.bsky.social · 12/06/2026
When you see the story about how the world now has its first trillionaire, and when you see the story about how laboratories in Congo have run out of supplies to test for Ebola, it is important to understand that in many ways these are the same story.
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PSC Support @pscsupport.bsky.social · 12/06/2026
Busy week for Mark! Yesterday he spoke at King's College Hospital, today he's speaking to the EASL PSC School in Hamburg to inspire new research & highlight the burden of PSC symptoms. As a small charity, we're making every penny count by joining online! buff.ly/DowUVeh #LetsBeatPSC
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