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Matthias B. Moor, MD PhD

@nephmoor.bsky.social
1.2K followers 523 following 32 posts

Dad of 4, husband, kidney doctor and researcher, at home in Switzerland and Sweden. Physiology, renal osteodystrophy, cell signaling, R, mouse population genetics. Opinions mine (he/him)

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Reposted by Matthias B. Moor, MD PhD
CosmicRami 🏳️‍🌈🏳️‍⚧️ @rami.spaceaustralia.com · 11/04/2026
LOL, trying to stay offline and do my work, and friends are sending me "LOOK AT THIS NEW PIC!" texts .... This one is worth it. First PoC and first woman to go around another world. Don't stop talking about this point. It's important. #ArtemisII
Astronauts Victor Glover and Christina Koch in their orange astronaut suits as they sit inside the side of a helicopter after it has landed
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Ms. Lonnie🦋🩵🫂 @lonsj.bsky.social · 11/03/2026
DC Keeps seeing new statues appearing The two were BFFs about a decade Gotta love creative artists 💙🩵💙
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Thibaut Brunet @thibautbrunet.bsky.social · 28/02/2026
Final version @nature.com of our paper describing unconventional multicellular development in a choanoflagellate inhabiting an extreme environment. A ton of new data since the first @biorxivpreprint.bsky.social preprint (which we've kept updating). A brief 🧵 (carried over from the old place)
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Eric Topol @erictopol.bsky.social · 29/01/2026
Discovery of an entirely new potential approach to atherosclerotic heart disease: targeted immunotherapy! Studies in human coronary arteries to reduce plaque and the mouse experimental model. Another win for spatial multiomics @science.org www.science.org/doi/10.1126/...
science.org
Targeting modulated vascular smooth muscle cells in atherosclerosis via FAP-directed immunotherapy
Vascular smooth muscle cell (VSMC) diversification drives atherosclerotic coronary artery disease (CAD). Mechanisms governing these cell state transitions remain unclear. We applied multiomic single-c...
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Paul Eric @pauleric70.bsky.social · 27/01/2026
Brian Allen 😎 London just joined Minnesota. Trafalgar Square filled with protesters demanding justice for Alex Pretti while opposing Farage. When state violence goes unchecked, the world notices. Solidarity doesn’t stop at borders. 🇬🇧 👏👏👏👏👏👏💙
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Will @willgarcia820.bsky.social · 24/01/2026
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Dimitri Drekonja, MD, MS @dimitridrekonja.bsky.social · 24/01/2026
Alex Pretti was a colleague at the VA. We hired him to recruit for our trial. He became an ICU nurse- I lover working with him. He was a good kind person who lived to help and these fuckers executed him. White. Hot. Rage.
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Armin Wolf @arminwolf.at · 26/11/2025
Diese Geschichte ist unfassbar. Weil der Trump-Regierung die Arbeit des Internationalen Strafgerichtshofs nicht passt, wird ein französischer Richter digital de facto ausgelöscht und bekommt keine Kreditkarte und kein Bankkonto mehr:
derstandard.at
"Digitale Auslöschung": Wie US-Sanktionen einen europäischen Richter lahmlegen
Nicolas Guillou ist von beinahe allen digitalen Diensten dieser Welt gesperrt – von Amazon bis Paypal. Europa wirkt dagegen völlig machtlos
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Matthias B. Moor, MD PhD @nephmoor.bsky.social · 25/12/2025
Unrealistic: they’re holding hands.
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Reposted by Matthias B. Moor, MD PhD
Adam Serwer @adamserwer.bsky.social · 14/03/2025
American politics makes a lot more sense when you realize that the GOP is afraid of pissing off the GOP base, and the Dems are afraid of pissing off the GOP base, but neither party is afraid of pissing off the Dem base.
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Python Software Foundation @python.org · 27/10/2025
TLDR; The PSF has made the decision to put our community and our shared diversity, equity, and inclusion values ahead of seeking $1.5M in new revenue. Please read and share. pyfound.blogspot.com/2025/10/NSF-... 🧵
python.org
The official home of the Python Programming Language
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Anton Gerashchenko @antongerashchenko.bsky.social · 21/10/2025
Tonight, a Russian drone hit a busy crossroads in Sumy. Nine people injured, over 10 vehicles damaged, windows shattered, civilian infrastructure damaged - Radio Liberty Casual Russian terrorism that will never make headlines but continues bringing tragedies to Ukrainians.
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Charles Gaba ✡️ @charlesgaba.com · 20/10/2025
DEAR DEMOCRATS: IF YOU DON'T INCLUDE THIS IMAGE IN EVERY CAMPAIGN AD YOU'LL BE COMMITTING POLITICAL MALPRACTICE.
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bioRxiv Genetics @biorxiv-genetic.bsky.social · 14/10/2025
Genetic dissection of tissue composition in genetically diverse mouse populations www.biorxiv.org/content/10.1101/202…
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Dr. med. Hank Schiffers @leanhealth.bsky.social · 01/10/2025
Die 2te Covid Infektion VERDOPPELT das Risiko für Longcovid bei KINDERN www.thelancet.com/journals/lan...
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Alexey Amunts @amunts.bsky.social · 03/09/2025
The scent of silence! Cool research in Cell @cellpress.bsky.social to brighten up your day🌹. The mystery of why some roses are fragrant and others aren't has an answer. It's called SCREP: a rose-specific gene that evolved from non-coding DNA 16.8 million years ago 👇
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Holger Hestermeyer @hhesterm.bsky.social · 08/08/2025
I am horrified. If you use US material, download all old reports you use. The record will be erased. Even that might not save you: every report sourced from the US will now have to be suspected of politicised manipulation and will in the future the same credibility as Iran’s human rights reports
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Matthias B. Moor, MD PhD @nephmoor.bsky.social · 30/08/2025
Looking for a PhD/Md-PhD candidate for a fully funded project at University Hospital Bern Switzerland to work at the intersection of kidney and bone biology. Please share, DM or comment. #NephSky #AskRenal
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SAINT JAVELIN @saintjavelin.bsky.social · 30/08/2025
I’m broken into pieces…
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Reposted by Matthias B. Moor, MD PhD
John @johngoodman.bsky.social · 26/08/2025
realistic Star Trek
A comic on the bridge from Star Trek the Next Generation.
Picard: COMMANDER DATA, PLEASE IDENTIFY THAT ROMULAN VESSEL.
Data: THAT'S A GREAT IDEA CAPTAIN!
IDENTIFYING A VESSEL IS A GREAT PLACE TO START - IN ANY TACTICAL OR STRATEGIC OUTER SPACE SITUATION.
THIS VESSEL APPEARS TO BE A 23rd CENTURY KLINGON BIRD OF
PREY! 🚀🦅✨
Picard: ARE YOU SURE?
LIKE I SAID WE'RE... PRETTY SURE IT'S ROMULAN.
Data: ...
Data: OF COURSE! SO SORRY ABOUT THAT, YOU'RE RIGHT!
ON CLOSER EXAMINATION IT'S A ROMULAN VESSEL! CAN I RECOMMEND SOME SOONG™ BRAND PRODUCTS THAT CAN HELP YOU WITH THAT?
Picard cradles his face in his hand in a gesture of frustration.
Data: DID I MENTION THE PLIGHT OF OPRESSED WHITES IN SOUTH AFRICA?
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Danielle Beckman @daniellebeckman.bsky.social · 01/08/2025
"Analyses of cancer survivors databases reveal that SARS-CoV-2 infection substantially increases the risk of cancer-related mortality and lung metastasis compared with uninfected cancer survivors." Mice data show #COVID drives the proliferation of previously dormant cancer cells.
Viral infection reactivates dormant cancer cells
Sometimes, cancer cells that have spread become ‘dormant’
but can start proliferating again later. A cue that can reactivate
them has been discovered.
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Melissa Hirst 💙🔥BLUE ADVOCATE OF LOVE AND ACCEPTANCE @melmayhem.bsky.social · 15/06/2025
I doubt anyone will see me post, but this needs to be known... if you have a visible following please repost 💙🔥💙 Admitting he wants "his people... aka US " to behave like north Korea for Kim Jong Un.🤬
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Dr Di Cook @visnut.bsky.social · 09/06/2025
If your department or University uses R in its teaching please consider requesting that they donate to the www.r-project.org/foundation/ annually. This funding is essential for supporting R distributions and package management.
r-project.org
R: The R Foundation
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GroovyShelly @groovyshelly.bsky.social · 24/05/2025
Here is the official Harvard University website! www.harvard.edu Here is their # if you'd like to speak to someone there!! +1 617-495-1000 The link to the Free Government courses is ... pll.harvard.edu/subject/gove...
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Jessica Berlin @berlinbridge.bsky.social · 24/05/2025
Last night Russia attacked a European capital with ballistic missiles and hundreds of drones. Today the story barely registers in international news headlines. Western normalization and acceptance of Russian atrocities in Ukraine is what makes them possible.
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Matthias B. Moor, MD PhD @nephmoor.bsky.social · 23/04/2025
The Kremlin’s Payoff? Russia Prepares 'Hooks' to Buy Off Trump open.substack.com/pub/olgalaut...
open.substack.com
The Kremlin’s Payoff? Russia Prepares 'Hooks' to Buy Off Trump
And a Trump Tower in Moscow: Here We Go Again...
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Reposted by Matthias B. Moor, MD PhD
Joel Topf @kidneyboy.bsky.social · 20/04/2025
If anyone gets nostalgic about how doctors have lost their diagnostic skills and things used to be better, please direct them to this case series from 1986 where following a seizure with an average Na of 108(!) 66% got an EEG 60% had an LP and 2 had brain biopsies #KnuckleHeadsItsTheSodium
https://www.nejm.org/doi/pdf/10.1056/NEJM198606123142401
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Evgen Istrebin @evgen-istrebin.bsky.social · 13/04/2025
The Ru economy has begun to collapse. Thread. Federal budget revenue growth has been slowing for 5 quarters in a row and in Q1 25 it was only +3.7%. Look at the chart, the last 5 quarters the revenue growth rate was +54%_+25%_+25%_+11%_+4% 1/
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NOELREPORTS @noelreports.com · 20/04/2025
🇨🇿 Czech FM Lipavský nailed it: “Putin’s Easter truce is like fasting between breakfast and lunch—while secretly snacking on candy.” 🎯 A PR stunt, not a real ceasefire.
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Louise @lousalome00.bsky.social · 20/04/2025
Wenn du dich von einem Hirntumor erholst und wieder an die Weltspitze kämpfst, aber deine Sponsoren wegen deiner Schwangerschaft Sorge vor einem falschen Invest haben. Frauenfeindlichkeit in seiner schlimmsten Form. Ich wünsche ihr, dass es Sponsoren regnet!
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Anna Gifty @itsafronomics.blacksky.app · 19/04/2025
Northwestern just announced that the university will meet the funding needs of any research that is being impacted by stop orders. LET'S GOOOOOOOOOOOOO! #edusky #academicsky wgntv.com/evanston/nor...
wgntv.com
Northwestern University to self-fund research despite Trump administration freeze
While university officials said they’ve still not received official word of such action, they acknowledged receiving about 100 stop-work orders from the federal government on roughly 100 fede…
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Matthias B. Moor, MD PhD @nephmoor.bsky.social · 19/04/2025
Ach so, der Senator scheint ihn getroffen zu haben. Gut immerhin das!
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Matthias B. Moor, MD PhD @nephmoor.bsky.social · 19/04/2025
Die wissen nicht mal, ob García überhaupt noch lebt: youtu.be/anULB25xcJE?...
youtu.be
REPORT: Trump’s El Salvador Prison Is A Death Camp | The Kyle Kulinski Show
YouTube video by Secular Talk
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Aaron Rupar @atrupar.com · 10/03/2025
the stock market is crashing so hard today it resembles a SpaceX rocket
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Matthias B. Moor, MD PhD @nephmoor.bsky.social · 06/03/2025
My main work from Stockholm is online as a preprint: FGF23 promotes renal immune cell infiltration and proinflammatory signaling in kidney disease models. Thanks to Mikhail Burmakin, Hannes Olauson and all other co-authors! #nephrology www.biorxiv.org/content/10.1...
biorxiv.org
The renal response to FGF23 shifts from phosphaturia towards inflammation in murine kidney disease models
Background: FGF23 excess is associated with morbidity and mortality, but the role of excessive circulating FGF23 concentrations as a mere biomarker or causative factor of pathology is controversial. H...
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Astrid Gall @astridgagall.bsky.social · 02/03/2025
Your favourite #sequence database is also available on two other continents, together with tools such as #BLAST: www.insdc.org (International Nucleotide Sequence Database Collaboration) 🧪
insdc.org
International Nucleotide Sequence Database CollaborationInternational Nucleotide Sequence Database Collaboration
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BildungAberSicher @bildungabersicher.net · 02/03/2025
RIP NIH Die National Institutes of Health (Nationale Gesundheitsinstitute). War(!) die wichtigste Behörde für biomedizinische Forschung in den USA. Mit einem jährl. Budget von ca. 30,3 Mrd. US$ (2015) war! die NIH die größte Einrichtung zur Forschungsförderung Die website nih.gov is down.
nih.gov
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Susann Schöniger @suschoe.bsky.social · 02/03/2025
In Odessa 🇺🇦 spricht man vom Mann ohne Anzug der einen Anzug ohne Mann getroffen hat.
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Josephine Kavanagh @ourhaus.bsky.social · 02/03/2025
You can freely access all PubMed records at Europepmc.org - I just checked and it's up and running.
europepmc.org
Europe PMCHome - Europe PMC
Europe PMC is an archive of life sciences journal literature.
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Madhu Pai, MD, PhD @madhupai.bsky.social · 02/03/2025
PubMed has gone dark A database I've used for over 30 years I hope and pray it comes back soon!
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KSlatteryResist @kslatteryresist.bsky.social · 01/03/2025
Danish Prime Minister Mette Frederiksen in Kyiv with world leaders calls Zelensky a hero, fighting a war for 3 years which was started by Russia. She urges Europe to increase support to UKR now, says Zelensky must be at the center of any negotiations with Putin #Voices4Victory youtu.be/JNs6wRvSpSU
youtu.be
Astonishing speech by Danish Prime Minister.
YouTube video by Dylan Burrill
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Matthias B. Moor, MD PhD @nephmoor.bsky.social · 01/03/2025
But let’s wait for more data and see, agree!
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Matthias B. Moor, MD PhD @nephmoor.bsky.social · 01/03/2025
2024/25? 😉 www.sciencedirect.com/science/arti... pubmed.ncbi.nlm.nih.gov/39878548/ Different populations though…
pubmed.ncbi.nlm.nih.gov
Fibroblast growth factor 23 and outcomes of atrial fibrillation: from clinical association to genetic evidence - PubMed
Our findings suggest that FGF23 is a potential biomarker for accessing AF-related outcomes. The paradoxical association between genetic FGF23 and serum FGF23 level highlights the need for further inve...
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Matthias B. Moor, MD PhD @nephmoor.bsky.social · 01/03/2025
Agree, now is not the time for practice change. It remains somewhere on the horizon, though, eg for early CKD or CHF. Further thoughts here: pubmed.ncbi.nlm.nih.gov/30853324/
pubmed.ncbi.nlm.nih.gov
FGF23: Clinical usefulness and analytical evolution - PubMed
Fibroblast Growth Factor 23 (FGF23) is a key hormone for the regulation of phosphate homeostasis. Over the past decades, FGF23 was the subject of intense research in the fields of nephrology and the c...
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Matthias B. Moor, MD PhD @nephmoor.bsky.social · 01/03/2025
Agree that it’s a bit provocative, as the human data are really difficult for now. I don’t think the Mendelian Random studies’ absence of evidence (genetics) speaks against an enviroimental exposure effect: I think it’s a cascade from Pi intake - increased FGF23 - inflammation/adverse outcomes. 2/2
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Matthias B. Moor, MD PhD @nephmoor.bsky.social · 01/03/2025
Why: Risk stratification. The human studies say so far that the association may be non-causal. If that is true and it’s non-causal (which most rodent data including our study argue against), then fasting Fgf23 might give a clue by how much cv risk should be tackled. 1/2
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Matthias B. Moor, MD PhD @nephmoor.bsky.social · 01/03/2025
Maybe some incentive to measure FGF23? #askrenal
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Matthias B. Moor, MD PhD @nephmoor.bsky.social · 01/03/2025
New manuscript! Excess of 🦴 hormone FGF23 worsens atherosclerosis in male but not female mice. Thanks to co-authors Karolina Lindberg, Olga Ovchinnikova, Daniel Ketelhuth, John Pirault, Hannes Olauson, Göran Hansson and Tobias Larsson. 👏 www.sciencedirect.com/science/arti...
sciencedirect.com
Fgf23 expression increases atherosclerotic plaque burden in male ApoE deficient mice
Components of both the innate and adaptive immune system impact on arterial walls in atherosclerosis. Fibroblast growth factor-23 (FGF23) is a phospha…
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