Claims that the gut microbiome causally contributes to autism regularly appear in the scientific literature and popular press. Mitchell et al. critically examine influential studies underpinning these...

Nature Communications - Here, the authors find that relative abundances of stress-sensitive gastrointestinal microbes at age 2 years predicts internalizing symptoms in middle childhood through...

Background Human gut microbes metabolize food and host secretions, consuming and producing small molecules that are important to health and homeostasis. Here, we present an atlas of diet- and microbio...

Carr et al. show how microbial community-scale metabolic models (MCMMs) predict personalized Clostridioides difficile colonization risk and probiotic efficacy. MCMMs reveal key metabolic strategies ex...

Artificial intelligence (AI) is a powerful tool that could be applied to microbiome research. This Perspective discusses best practices and current limitations with the application of AI in microbiome...

Microbial-based and microorganism-targeting therapies are emerging to prevent or treat preterm infant complications, but more preclinical research and clinical evidence is needed.

New policy could be a windfall for makers of nonanimal models

PLEASE SHARE Excited to announce that we have several PhD fellowship positions to fill in our laboratory at Teagasc Food Research Centre, Moorepark, Ireland over the coming months. These relate to: (...

The human microbiome (microbes living in and on us, and their genomes) is a critical yet often overlooked factor influencing public health. Public health has […]

Here, the authors profile bacterial engraftment in UC patients receiving FMT from a single donor and placebo samples to estimate noise, showing a significant level of false-positive engraftment, which...

Cai et al. revealed that transplanting gut microbiota from women with fibromyalgia—a chronic widespread pain condition of unknown etiology—into mice induces pain. It also induces phenotypes commonly o...

Unravelling the features of the whole-body response to acute stress exposures is critical to understand this neglected building block of chronic stres…

Our collaborative team of researchers (bioethicists (Kieran and Diego), bioinformaticians (Rob), host microbial ecologists (Sue and Emma), and soil microbial ecologists (Mallory), had our first co-authored paper published in mSystems! Our paper is a commentary on the concept and need for microbiome stewardship, and outlines the research and policy priorities that are the focus of our ongoing research.

Industrialized diets – high in processed foods and low in fibre – disrupt the gut microbiome and predispose us to chronic diseases, such...

Neuroscience; Microbiome

Is it possible to restore the human gut microbiome in industrialized settings and reintroduce microbial species that have been lost? In healthy adults, Li et al. found that consuming a diet mimicking ...

The Human Microbiome Compendium is a unified database of publicly available human gut microbiome 16S samples, built with the integrated data from hundreds of independent projects. The compendium is us...

Using publicly available genome sequence data generated over the past three decades, JGI researchers assess the known fraction of microbial diversity.

Here, the authors profile the gut microbiota and metabolites of Indian agrarians to understand the impact of fermented foods consumption, and identify seasonal variation in the gut microbiota structur...

Location: 22 St. Clair Avenue East, Toronto, Ontario, M4T 2S7 About Us The Weston Family Foundation is a family-led charitable foundation that focuses on creative solutions in the areas of healthy agi...

Yang et al. show an age-related increase in the microbial-derived metabolite phenylacetylglutamine that drives host cellular senescence by inducing DNA damage and mitochondrial dysfunction via ADR–AMP...

A family of host-derived bile acid–methylcysteamine conjugates functions as FXR antagonists, forming part of a microbiota-dependent metabolic network that regulates FXR-dependent physiology.

This Perspective reflects on advances made in the field of human gut microbiome-derived biotherapeutics, from faecal microbiota products to rationally designed second- and third-generation live biothe...

Letters: Prof Mark Pallen, Dr Aimee Parker, Prof Nick Loman and Prof Alan Walker take issue with an article that discussed the existence of a brain microbiome and its impact on diseases

Microbiota-released extracellular vesicles (MEVs) have emerged as a key player in intercellular signaling. In this study, a multi-level analysis revealed presence of a diverse array of biologically ac...

This year, ISB hosted a two-day virtual microbiome course and one-day symposium dedicated to exploring the gut-brain axis.

Postdoctoral Scholar in Microbiome and Child Development in Calgary, AB, ...