iiinova — where your digital self keeps evolving

Reposted by Shai Bel (The Mucus Man)

Leah Houri-Zeevi @leahhouri.bsky.social · 25/09/2026

🩸🩸🩸TODAY WE SHARE TWO MAJOR DISCOVERIES🩸🩸🩸 1. We peered into genomes and brains of the rare mosquitoes that QUIT feeding on blood and found what biting is built from 2. Humans got rid of isoleucine in their blood, malaria suffers from it, and mosquito proteomes budget for it THREADS>

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Caroline Bartman @cbartman.bsky.social · 10/09/2026

Excited to share the first published paper from my lab! Postdoc Helen Jordan led this study on 1) how metabolites change differently in inflammation in tissues versus in cells in a dish and 2) the role of one of the most-increased metabolites, soluble sialic acid www.jbc.org/article/S002...

jbc.org

Metabolomics of in vivo inflammation identifies soluble sialic acid as a conserved myeloid-cell metabolite

During an immune response, metabolism changes dramatically. Metabolites are oxidized to power immune cell functions, serve as building blocks for proliferation, and act as effectors to regulate pathog...

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Shai Bel (The Mucus Man) @mucusman.bsky.social · 02/09/2026

Thanks Joe! Hope I get to see you more often.

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Shai Bel (The Mucus Man) @mucusman.bsky.social · 02/09/2026

Thanks Mike. Looking forward to being closer to my fellow gut people.

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Shai Bel (The Mucus Man) @mucusman.bsky.social · 01/09/2026

🚨🚨 THE MUCUS IS COMING TO AMERICA!! I'm excited to announce that I will be joining the wonderful @uwmadisonmmi.bsky.social to continue exploring the wonders of mucus!

static.klipy.com

Elmo Wants More Slime

ALT: Elmo Wants More Slime

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Reposted by Shai Bel (The Mucus Man)

Eric Topol @erictopol.bsky.social · 20/11/2025

New discovery in ulcerative colitis: a bacterial toxin that kills macrophages and increases inflammation, which could be the foundation for a new treatment science.org/doi/10.1126/... science.org/doi/10.1126/... @science.org

science.org

A bacterial toxin disarms gut defenses against inflammation

Macrophage-toxic bacteria from patients with ulcerative colitis worsen gut inflammation in mice

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Reposted by Shai Bel (The Mucus Man)

Michael Baym @baym.lol · 20/11/2025

Hot off the press! Our latest paper led by @fernpizza.bsky.social, understanding how plasmids evolve inside cells. These small, self-replicating DNA circles live inside bacteria and carry antibiotic resistance genes, but also compete with one another to replicate. 1/ www.science.org/doi/10.1126/...

science.org

Intracellular competition shapes plasmid population dynamics

From populations of multicellular organisms to selfish genetic elements, conflicts between levels of biological organization are central to evolution. Plasmids are extrachromosomal, self-replicating g...

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Shai Bel (The Mucus Man) @mucusman.bsky.social · 20/11/2025

I'm happy to share a perspective that @soniamodilevsky.bsky.social and I wrote about a new and exciting paper in @science.org with big implications for IBD. Check it out: A bacterial toxin disarms gut defenses against inflammation | Science www.science.org/doi/10.1126/...

science.org

A bacterial toxin disarms gut defenses against inflammation

Macrophage-toxic bacteria from patients with ulcerative colitis worsen gut inflammation in mice

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Reposted by Shai Bel (The Mucus Man)

Mark Mandel @markjmandel.bsky.social · 03/09/2025

Additional talks this fall include @mucusman.bsky.social, Selena Sagan (hosted by @uwmadisonmdtp.bsky.social), @teralevin.bsky.social, @csdetweiler.bsky.social, Jan Rehwinkel, Sung Chul Park, Claire O'Leary, Sean Crosson, @torreslab.bsky.social, and Patricia Champion

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Shai Bel (The Mucus Man) @mucusman.bsky.social · 14/08/2025

🚨While the world is burning down around us, I'm happy to share that I've been promoted to Associate Professor with tenure. Though this is considered a personal achievement, it was only possible due to the wonderful trainees in the lab, who carried me here❤️.

media.tenor.com

a man is writing prof on a blackboard

ALT: a man is writing prof on a blackboard

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Dor Salomon @drdorsalomon.bsky.social · 18/06/2025

This is unacceptable. A total disgrace. Shame on the organizers. Leave science out of it! I am appalled to see this in the microbiology community 🦠

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Reposted by Shai Bel (The Mucus Man)

Ariel Munitz @arielmunitz.bsky.social · 18/06/2025

Total disgrace!

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Leigh Knodler @leighknodler.bsky.social · 03/06/2025

Just a few spots remaining for the GRC Salmonella Biology and Pathogenesis meeting to be held in August. The final program is now online. www.grc.org/salmonella-b... Apply now to hear about the latest scientific discoveries about Salmonella, meet up with old friends, make new friends......

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Shai Bel (The Mucus Man) @mucusman.bsky.social · 31/05/2025

One of the best performances in a final

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Waggoner Lab @labwaggoner.bsky.social · 28/05/2025

A coordinated cellular network regulates tolerance to food @nature.com @annarudnitsky.bsky.social @kedmiranit.bsky.social www.nature.com/articles/s41...

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Reposted by Shai Bel (The Mucus Man)

Ranit Kedmi @kedmiranit.bsky.social · 27/05/2025

Incredible! Over the past 2 months, 5 independent manuscripts — from @TheColonnaLab, Dan Littman, @gardnerlabucsf.bsky.social and @chrysothemisbrown.bsky.social , and our own (now in @nature.com, www.nature.com/articles/s41...), reports that the dietary pTreg program is initiated by RORγt⁺ APCs. /1

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Reposted by Shai Bel (The Mucus Man)

Irene Salinas Remiro @drsalinaslab.bsky.social · 27/05/2025

Our latest paper is now out. A long standing collaboration with the Sunyer lab where our teams show the requirement for secretory IgM in the gut mucosa to control microbiota homeostasis and metabolism. Enjoy! #sIgM #mucosalimmunology www.nature.com/articles/s41...

nature.com

Secretory IgM regulates gut microbiota homeostasis and metabolism - Nature Microbiology

Rainbow trout with depleted secretory IgM reveal interesting insights into the elusive role of this immunoglobulin in maintaining gut microbiota.

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Reposted by Shai Bel (The Mucus Man)

Asaf Levy @asaflevylab.bsky.social · 25/05/2025

Tomorrow I will host Will Ratcliff @wcratcliff.bsky.social in the virtual microbiology journal club. Title: "Exploring the origin of multicellularity in real time: what we've learned from 10,000 generations of laboratory evolution" link below -

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Germán Bonilla-Rosso @germusthermophilus.bsky.social · 22/05/2025

🧪🔬🦠🧫🌍 This is the kind of paper we should all be waiting for! Because sadly we still don't have reliable methods to count bacterial abundance from microbiomes. (I haven't read it yet, but I love the intention already) www.nature.com/articles/s41...

nature.com

Absolute quantification of prokaryotes in the microbiome by 16S rRNA qPCR or ddPCR - Nature Protocols

This protocol enables rigorous and reproducible quantification of prokaryotic concentration in stool samples by 16S rRNA qPCR or ddPCR.

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Cadwell Lab @cadwelllab.bsky.social · 17/05/2025

Congratulations Xiaomin Yao and Eugene Rudensky for publishing this story @cp-immunity.bsky.social! Big thank you to NIH for making this work possible. Here’s a brief summary of this 🤯 finding about a gene variant that YOU 🫵 most likely have 1/n

kwnsfk27.r.eu-west-1.awstrack.me

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Reposted by Shai Bel (The Mucus Man)

Ananya Parthasarathy @ananya-p.bsky.social · 27/04/2025

Had an amazing time at #APS2025, and so happy to have presented my poster and flash talk! First conference ✅

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