iiinova — where your digital self keeps evolving

Evelina Tutucci @anilevetu.bsky.social · 06/10/2026

🧬Registration for The Dutch RNA Club Annual Symposium is now open! Coming up on Friday, 13 November 2026 at the O|2 Building, Vrije Universiteit Amsterdam. Register here: sites.google.com/view/dutchrn...

sites.google.com

Dutch RNA Club

A one-day summit of talks, posters and networking

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Nobel Prize @nobelprize.org · 05/10/2026

BREAKING NEWS The 2026 Nobel Prize in Physiology or Medicine has been awarded to Karl Deisseroth, Peter Hegemann and Georg Nagel “for their discoveries concerning light-gated ion channels and optogenetics.”

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Alan Gerber @alangerber.bsky.social · 28/09/2026

Preprint alert 🚨: We built a CRISPRi screen for a part of the genome that is unusually awkward to perturb: the RNA Pol III transcriptome. Hundreds of tRNA genes, lots of sequence similarity, plenty of redundancy... Turns out the biology had a few surprises for us 👇 www.biorxiv.org/content/10.6...

biorxiv.org

Targeted CRISPRi screening reveals unexpected resilience across the RNA polymerase III transcriptome

Increased RNA polymerase III (Pol III) activity and tRNA abundance are widely linked to cancer cell growth, yet the functional requirement for individual Pol III genes and core components remains uncl...

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Evelina Tutucci @anilevetu.bsky.social · 25/09/2026

Halting translation by the letter with sequence-selective small molecules. Review Nature Chemical Biology share.google/fS99JiZSil8j...

share.google

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Will Ratcliff @wcratcliff.bsky.social · 15/09/2026

1/17 Submissions are now open for the 2027 Microbial Population Biology GRC! We expect this meeting to be extraordinarily oversubscribed. If you want to come, time is of the essence--apply ASAP! June 27–July 2 • Andover, NH www.grc.org/microbial-po...

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Pombo-GarciaLab @pombo-garcialab.bsky.social · 26/08/2026

It was a great pleasure to celebrate the 25th anniversary of @mpi-cbg.de reconnect with colleagues and friends. A wonderful occasion to honour the institute’s spirit of building a community of People pushing the boundaries of science and, of course, having fun along the way! 🔬🥂✨ #25yearsmpicbg

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Christian Kost @kostchristian.bsky.social · 24/08/2026

Very happy that our paper Obligate cross-feeding of metabolites is common in soil microbial communities just came out in Nature Microbiology. See here 👇 Paywalled version: www.nature.com/articles/s41... Free read-only version: rdcu.be/fBHAb

nature.com

Obligate cross-feeding of metabolites is common in soil microbial communities - Nature Microbiology

Cultivation-dependent techniques, computational analyses and genome-scale metabolic models show widespread amino acid auxotrophies, suggesting that soil microorganisms exist within integrated ecologic...

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Matthew Taliaferro @jmtali.bsky.social · 12/08/2026

Excited to share our newest work! We asked whether RNA molecules need to be in a specific place in the cell to do their job. We found that a single RNA must reach the midbody, the structure that pinches two dividing cells apart, for cell division to finish efficiently. 🧵⬇️

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Marko Kaksonen @kaksonen.bsky.social · 11/08/2026

Endocytic clathrin coats are surprisingly dynamic: triskelia turn over in seconds. How is the turnover regulated and what is it for? Read Anne-Laure Boinet's preprint with @rouxlab.bsky.social www.biorxiv.org/content/10.6...

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Heran Darwin, PhD @heran.bsky.social · 10/08/2026

BlueSky doesn't seem to spread the word around as effectively as that other app so I'm reposting this incredible opportunity again (and again!). Please repost and spread the word to strong candidates. Thank you!

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Kin Pan Chung @kinpanchung.bsky.social · 22/06/2026

We're hiring a PhD candidate! 🔬 Are you fascinated by cytoplasmic genetics and eager to uncover the mechanisms underlying maternal inheritance of plastids and mitochondria? If so, join our group and contribute to our ERC-funded research "CytoInP"!🌟 Application link: www.wur.nl/en/vacancy/p...

wur.nl

PhD position: Manipulating plastid and mitochondrial inheritance in plants

Our group investigates the maternal inheritance of plastid and mitochondrial genomes in plants, with the goal of uncovering the mechanisms that govern this process.

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Science Magazine @science.org · 20/06/2026

In a new Science study, researchers provide the first estimate of the global density and biomass of arbuscular mycorrhizal fungal networks. Learn more: scim.ag/4vfgZRv

Mycorrhizal fungi form an interconnected network of hyphae, the tube-like structures pictured here.

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Reese Richardson @reeserichardson.bsky.social · 05/06/2026

The Thermo Fisher situation keeps getting worse. We've now collected 450+ problematic images presented as verification data in TF's antibody catalog. This includes: 🖌️ Dozens more images with duplications or painting 🖨️ Hundreds of blots that all share the same background (behold slideshow below)

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Manlio De Domenico @manlius.bsky.social · 22/05/2026

Can a biological system acquire the capacity to generate two distinct life forms from one genome? Some dimorphic 🍄 live with a built-in capacity to change form, growing either as single yeast-like cells or as filamentous networks depending on their surroundings. 🧪🌐 www.nature.com/articles/s41...

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Meike Wortel @meikewortel.bsky.social · 15/05/2026

How do human gut microbiome species interact? Can we explain their communities and invasion patterns form environmental factors alone? PhD students Pim van Leeuwen and Pietro Gadaleta set out to test this! TLDR: Indeed, for the 10 common species we can! Paper out in mSystems: doi.org/10.1128/msys...

doi.org

Environmentally mediated interactions predict community assembly and invasion success in a gut microbiota synthetic community | mSystems

The stability of the human gut microbiome is crucial for host health, with opportunistic pathogen invasions causing diseases and healthy strain replacements needed for recovery. The microbiota’s compl...

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Marvin Tanenbaum @marvintanenbaum.bsky.social · 13/05/2026

For 40 years the 8-nt ‘Kozak Sequence’ was thought to mark sites of translation initiation. In a new study, we revise this model by identifying an ~80-nt sequence—the extended Translation Initiation Sequence (eTIS)— that guides ribosomes to correct start sites. 🧵 www.biorxiv.org/content/10.6...

biorxiv.org

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Christine Mayr @christinemayr.bsky.social · 08/05/2026

If you want to know what 3′UTRs with long conserved sequence stretches do, check out our BioRxiv preprint doi.org/10.64898/202.... They form functional intermolecular 3′UTR-3′UTR interactions that enable co-folding of proteins to rapidly induce transcriptional programs.

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Edward Wallace @ewjwallace.bsky.social · 29/04/2026

How do fungi grow directionally? We think part of the mechanism involves local translation of mRNA near the tip, especially of cell wall components. Delighted to share our preprint showing that an RNA-binding protein, SsdA/Ssd1, is trafficked to the tip of growing fungal filaments.

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Carlos Ribeiro @ribeirocarlitos.bsky.social · 17/04/2026

Today we mourn the passing of our beloved central dogma. It served Crick well. But it is time to let go. www.science.org/doi/10.1126/...

science.org

Science | AAAS

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Will Ratcliff @wcratcliff.bsky.social · 07/04/2026

1/25 New paper out in PNAS! We show that the fitness costs of reproductive specialization, where somatic cells give up reproduction, scale inversely with organism size. Larger organisms can afford far more soma, removing a key barrier to multicellular complexity.

pnas.org

The fitness costs of reproductive specialization scale inversely with organismal size

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Mandy Muller @mandymuller.bsky.social · 25/03/2026

🚨 Postdoc position open - please repost! Join our lab in Lausanne🇨🇭to study KSHV, virus–host interactions & RNA decay + great quality of life right by Lake Leman and the Alps ⛰️ Apply here 👉 sites.google.com/view/muller-...

sites.google.com

Muller Lab

Welcome to the Muller Lab website - here are our latest news:

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Bram van Dijk 🏳️‍🌈 @bramvandijk.bsky.social · 23/03/2026

Phd Position alert 🚨 Join our project ASTRAfun (Adaptation and Starship Traffic in Root-Associated fungi), in which we will use computational models to unveil the hidden dynamics of fungal evolution. It’s not going to be just regular fun. It’s going to ASTRAfun. 🤓 www.uu.nl/en/organisat...

uu.nl

PhD Position in Computational Modelling of Fungal Evolution

How do giant mobile elements called ‘Starships’ reshape fungal plant pathogens? Help us computationally model their spread and impact in nature and agriculture!

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Ben Auxier @benauxier.bsky.social · 17/03/2026

Now up on bioRxiv! Working with @dianzheng.bsky.social and Jan van Kan, we tested how DNA is distributed between nuclei in multinucleate fungal spores. www.biorxiv.org/content/10.6...

biorxiv.org

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Evelina Tutucci @anilevetu.bsky.social · 19/03/2026

Multiple nuclei means multiple chromosome sets in Botrytis cinerea and Neurospora crassa. www.biorxiv.org/content/10.6...

biorxiv.org

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Alejandro Montenegro @aemonten.bsky.social · 09/03/2026

"we developed Multiplexed Error Robust Fluorescence In Situ Hybridization 2.0 (MERFISH 2.0), an optimized spatial transcriptomic imaging chemistry to enhance profiling of fragmented and highly crosslinked RNA" www.biorxiv.org/content/10.6...

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GdR ImaBio 🔬 @gdrimabio.bsky.social · 09/03/2026

🔬🌿Official launch of the #AGILE_project, an MSCA doctoral network funded by the European Union. #AGILE aims to train a new generation of plant scientists. Team CODED @igred.fr is looking for 15 international doctoral students. For more information and/or to apply : 👉 www.msca-agile.eu

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Sophie G Martin @sophiemartinlab.bsky.social · 03/03/2026

You are finishing your PhD and looking to continue in science? The Martin lab @biology-unige.bsky.social has an open postdoctoral position in cell biology to study cell-cell fusion. For more information, please consult mocel.unige.ch/research-gro.... Thanks for reposting!

mocel.unige.ch

Contact/Job - Department of Molecular and Cellular Biology - UNIGE

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Mara Mueller @muellermara.bsky.social · 19/02/2026

Mammalian cells form hibernating disomes akin to those in bacterial cells - but connected via ribosomal RNA www.science.org/doi/10.1126/... co-first with: @andschwarz.bsky.social with: @lea-dietrich.bsky.social, @sgiando.bsky.social, @erin-schuman.bsky.social and many more 🧵 0/6 #MolBio 🧪

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Evelina Tutucci @anilevetu.bsky.social · 23/02/2026

Ribosomal RNA expansion segments mediate the oligomerization of inactive animal ribosomes www.science.org/doi/full/10.... From Erin Schuman's lab @erin-schuman.bsky.social #RNAbiology

science.org

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Marvin Tanenbaum @marvintanenbaum.bsky.social · 12/02/2026

Out now in Cell Systems: We develop a technique to visualize influenza A virus in live cells with single viral RNA resolution. Combined with precise readouts of viral transcription, we map the whole influenza A viral life cycle and identify key bottlenecks in infection. www.cell.com/cell-systems...

cell.com

Live-cell single-vRNP imaging identifies viral gene expression signatures that shape influenza infection heterogeneity

In this study, an imaging technology, “VISUN,” is developed that allows live-cell visualization of unmodified influenza virus during infection with single-vRNP resolution. Combining VISUN with multipl...

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Robert Arkowitz @robertarkowitz.bsky.social · 10/12/2025

👉Excited to share our latest work @natmicrobiol.nature.com, revealing a decrease in cytoplasmic crowding during filamentous growth in the human fungal pathogen Candida albicans. Furthermore we found that inhibition of ribosome biogenesis can trigger filamentous growth in this pathogen rdcu.be/eT1Su

rdcu.be

Decreased cytoplasmic crowding via inhibition of ribosome biogenesis can trigger Candida albicans filamentous growth

Nature Microbiology - During filamentous growth in the human fungal pathogen Candida albicans, a reduction in ribosome concentration leads to a decrease in macromolecular crowding. Inhibition of...

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Michael Feldbrügge @mfeldbruegge.bsky.social · 02/02/2026

Happy to announce that our review article on vesicle-coupled mRNA trafficking is now availalbe @mibinet.bsky.social #EMBOrnaLocalization link.springer.com/article/10.1...

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allepasse.bsky.social @allepasse.bsky.social · 26/01/2026

I’m happy to share the main result of my PhD, which you can find on bioRxiv www.biorxiv.org/content/10.6.... If you are interested in learning about a new way to perform DNA-PAINT multiplexing, which we call Combi-PAINT, or if you are interested in the study of mRNA conformation, keep reading! 1/10

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Maximilian Madern @maxmadern.bsky.social · 20/01/2026

Excited to share our new paper! We developed a method to visualize proteasomal degradation at the single–molecule level in live cells, enabling us to dissect distinct modes of substrate engagement, probe co-factor dependence, and study proteasome–ribosome collisions. www.biorxiv.org/content/10.6...

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Society for the Protection of Underground Networks (SPUN) @spun.earth · 19/01/2026

The World Champion of Fungus talks punk science in @nytimes.com. Thank you @alanburdick.bsky.social for sitting down with SPUN's @tobykiers.bsky.social, this year's @tylerprize.bsky.social Laureate. 🔗 Read here: buff.ly/4TVueaz

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@tim_stasevich @tim-stasevich.bsky.social · 19/01/2026

Happy New Year all. I know it's been a draining and difficult year for science in general, but wanted to share some good news: our intrabody paper has now been published in Science Advances with lots of additional data. www.science.org/doi/10.1126/...

science.org

AI-assisted protein design to rapidly convert antibody sequences to intrabodies targeting diverse peptides and histone modifications

AI-powered pipeline converts antibodies into functional intrabodies, enabling live-cell imaging of peptides and histone marks.

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Society for the Protection of Underground Networks (SPUN) @spun.earth · 13/01/2026

We need help keeping the world’s largest living library of mycorrhizal fungi alive. The INVAM mycorrhizal culture collection is at risk due to federal funding cuts. Its loss would be catastrophic. Link to donate: 🔗 invam.ku.edu/donate Read @theguardian.com article: 🔗 buff.ly/hkEGXgu

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Evelina Tutucci @anilevetu.bsky.social · 10/01/2026

Happy to share that the our manuscript "Cyclin CLB2 mRNA localization and protein synthesis link cell cycle progression to bud growth" is now finally out in its final form @natcomms.nature.com www.nature.com/articles/s41... Below a short🧵 with the key findings!

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Guillaume Jacquemet @guijacquemet.bsky.social · 09/01/2026

I am looking for two postdocs to join our lab - One (bio)image analyst - One cell biologist interested to work on lymphatics! The positions will open soon, be in touch!

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