iiinova — where your digital self keeps evolving

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Karl Deisseroth @deisseroth.bsky.social · 9h

Thank you to everyone sharing in this moment! I’m so grateful to all my trainees & collaborators… dlab.stanford.edu/group-members (pic: Peter and I together in 2017) Reading for all those asking: for technical details: dlab.stanford.edu for everyone: deisseroth.org/projections

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Physics World @physicsworld.bsky.social · 13h

Karl Deisseroth, Peter Hegemann and Georg Nagel win Nobel Prize for "discoveries concerning light-gated ion channels and optogenetics" - a breakthrough that enables mapping of the brain in a way that we could once only dream of. 🧪⚛️ physicsworld.com/a/inventors-...

physicsworld.com

Inventors of optogenetics win Nobel Prize in Physiology or Medicine – Physics World

Karl Deisseroth, Peter Hegemann and Georg Nagel are joint winners of the 2026 prize

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Rob Campbell @raacampbell.com · 04/10/2026

Preprint is out! Our BakingTray software turns a 2-photon microscope into a serial-section tomography system for automated whole-organ imaging. ~€35k to convert an existing scope. 11 systems worldwide, >7,000 samples at SWC alone #neuroskyence #microscopy www.biorxiv.org/content/10.6...

A BrainSaw at the Max Planck Institute for Brain Research, Frankfurt. A Nikon 16x water-immersion objective on a 400 µm travel PIFOC allows for fast z-stacks. Samples are imaged and cut in the clear water bath. A Leica VT1000 vibratome is seen to the right with a mounted blade.

How BrainSaw works. Samples are embedded in an agarose block, which is glued to a slide and clamped into a water bath. The bath sits on a three-axis stage under a 2-photon microscope; the stage moves the sample for both tile scanning and slicing. The microscope images the exposed face of the block, the vibratome cuts off the imaged layer, and the cycle repeats until the samples have been fully imaged. Data are stitched automatically and are ready for downstream analysis. Logos below: BrainSaw (hardware), BakingTray (acquisition software), StitchIt (stitching).

Coronal section of an Sst-tdTomato mouse brain imaged on BrainSaw. tdTomato-expressing cells are shown in yellow, scattered through cortex and hippocampus; tissue autofluorescence is shown in blue.

Coronal section of a mouse brain with three neighbouring viral injections targeting layer 5 of V1, expressing mCherry (red), eGFP (green) and BFP (blue). The thick apical dendrites of the labelled neurons are clearly visible, as are their axons projecting to distant targets. Image credit: Alex Fritzl.

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Christopher Webb @cwebbonline.com · 01/10/2026

Fellas, we have to talk to our sons while they’re still young. This foundation👇🏽 is the way…

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Maruja Torres @marujatorres.bsky.social · 30/09/2026

Venid, venid‼️

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Hello Bio @hellobio.bsky.social · 29/09/2026

Do you work with ionotropic glutamate receptors? 🤔 We’ve made it easier to find the reagents you need. Our new hub brings together our products that target NMDA, AMPA & kainate receptors, all in one place 🙌 Explore the hub: ow.ly/frxH50ZSxJU #receptors #AMPA #NMDA

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André Nadler @nadlerlab.bsky.social · 23/09/2026

This my friends, this is the big one. A long time coming. Lipid Cell Biology is coming of age and even for a hot field, this is a true game changer. This dataset will keep us all busy for years to come. Congrats to everybody on this amazing crew!!! Go party!!

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Stephane Vassilopoulos @stefvass.bsky.social · 22/09/2026

Great to see this finally out! ✨ A real pleasure to contribute to this special issue celebrating 50 years of #Clathrin and to revisit how this superstar coat keeps surprising us ⚽🔬

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Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦ @dudinlab.bsky.social · 17/09/2026

we do see some signals with WGA, depending the species or cell type actually in some Ichthyos. But we are planning a more concrete screen of multiple lectins across many species in ExM, to better give tools for the community. Obviously the ones who will gain most are people working on non-models

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Rémi Fronzes @fronzeslab.bsky.social · 07/09/2026

Met some locals during my trail run this weekend. They were not impressed by my pace.

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Biohub @biohub.org · 04/06/2026

Better vitrification = better cryo-ET. We've opened an RFA for two-year grants to advance vitrification techniques for biological samples—welcoming applications from researchers in heat transfer, cryogenics, and materials science. Apply here: bit.ly/4uip6eJ

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Mel Andrews @bayesianboy.bsky.social · 17/06/2026

When utilized in literature review, LLMs consistently 1. fail to mention female authors in female-led literatures, 2. insist that men are more influential or more heavily cited when this is contradicted by objective citation counts, and 3. attribute women’s work to hallucinated male scholars.

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Florian Wollweber @florianwollweber.bsky.social · 05/09/2026

Exciting news! Our @erc.europa.eu StG project ARCHAEAOLOGY got funded 🎉 We’ll combine cryoET/EM, ExM & spatial omics to explore the subcellular organization of Asgard archaea. Job ads coming soon! 🦠 ❄️ 🔬 #TeamTomo #ArchaeaSky #MicroSky

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Christopher Webb @cwebbonline.com · 03/09/2026

This iconic 1971 photo of Gloria Steinem and Dorothy Pitman Hughes has always said so much without saying a word. Two women. Two raised fists. One shared fight for equality. Dorothy passed in 2022. Now Gloria is gone too. Two giants who helped change America. Rest in power, Gloria. ✊🏼✊🏾

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Monica_BIC @monica-bic.bsky.social · 28/08/2026

Quiz: what microscopy technique did I use for this image? Enjoy your weekend! #FluorescentFriday #FluorescenceFriday

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Monica_BIC @monica-bic.bsky.social · 21/08/2026

Back to work... just sharing new projets. Hippocampal neurons cryo-fixated and labeled for actin (Red Hot) and membranes (Cyan). The only way to fix actin waves... #FluorescenceFriday or #FluorescentFriday

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jared toettcher @toettch.bsky.social · 24/07/2026

New Toettchlab paper alert! Harrison Oatman just published his beautiful work combining software design for "smart" microscopy+optogenetics and some really beautiful work understanding EGFR-driven collective cell migration. www.cell.com/cell-systems...

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Louise Fougere @louisefougere.bsky.social · 14/08/2026

Super happy to share with Magali Grison, @yohannboutte.bsky.social and Christel Poujol this amazing method of super-resolution in plant-cell microscopy 🤗 always further ! always more extraordinary !🔬 🪴 @lbm-bordeaux.bsky.social @bic-bordeaux.bsky.social @univbordeaux.bsky.social

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Anh Hoang Le, PhD 🏳️‍🌈🏴󠁧󠁢󠁳󠁣󠁴󠁿🇻🇳 @anhhle2702.bsky.social · 07/08/2026

Hot take but any reporter that makes the actin network visible will make any cell look awesome under the microscope! These Xenopus 🐸 ectoderm cells are expressing an actin tension sensor, and you can see the retrograde flow very nicely. Actin is better than microtubules 😁 #FluorescenceFriday

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BIC_Bordeaux @bic-bordeaux.bsky.social · 04/08/2026

#ImageOfTheMonth August 2026 🔬 Stunning 8x expanded human hippocampus! Microglia (pink), lysosomes (yellow), nuclei (grey). Collaboration: Ana Victoria Prádanos Senén (@cbm-csic-uam.bsky.social) & @monica-bic.bsky.social (BIC). #Neuroscience #ExpansionMicroscopy

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EMBL Events @events.embl.org · 21/07/2026

Farewell and thanks to all participants, trainers and organisers of #EMBLSuperResolution An inspiring 6-day course on Time-resolved STED nanoscopy has come to an end, covering the entire range of skills needed to apply STED nanoscopy in life sciences through lectures and hands-on tutorials 🔬

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Alfred Millett-Sikking @amsikking.bsky.social · 20/07/2026

Ultrafast 3D imaging just got faster! Introducing: "Instant dual-view Snouty (iDV-Snouty) light-sheet microscopy" -> Double the data rate of a Snouty microscope by adding a 2nd view! Use the extra view for a variety of imaging modes! Article here: amsikking.github.io/idv-snouty_l...

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STCmicrobeblog @stcmicrobeblog.bsky.social · 20/07/2026

now, compare 𝘗𝘰𝘥𝘰𝘱𝘩𝘳𝘺𝘢 𝘤𝘰𝘭𝘭𝘪𝘯𝘪 with the suckophant, seriously! #ProtistsOnSky

the suckophant from 'yellow submarine' movie

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CSIC @csic.es · 20/07/2026

¡La victoria de la Selección Española hizo a temblar a nuestro país!🏆🇪🇸 ➡️ El #CSIC registró en Cataluña las vibraciones por los saltos y celebraciones durante la final de la #CopaMundialFIFA con los sismómetros del #GEO3BCN_CSIC ¡Enhorabuena! 👏🏻⚽️

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Monica_BIC @monica-bic.bsky.social · 20/07/2026

Perfect day for blooming… you know if you know!!! #worldcup2026

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CNRS Biologie @cnrsbiologie.bsky.social · 20/04/2026

🏅 Nouvelle distinction @emmanuellebayer.bsky.social reçoit la médaille d’argent du @cnrs.fr pour ses travaux en biologie végétale. Comprendre quand une cellule doit s'ouvrir, se fermer, laisser passer ou se protéger : une question au-delà de la biologie 🔬 À découvrir : buff.ly/wtLXvgG

buff.ly

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Emmanuelle Bayer @emmanuellebayer.bsky.social · 23/06/2026

Thrilled and grateful to receive an ERC Adv Grant! 🎉 We will explore how the endoplasmic reticulum contributes to plant ☘️ cell-to-cell communication 📞. 🤝 Thanks to my team, collaborators, and @bic-bordeaux.bsky.social. More details 👇 www.aquitaine.cnrs.fr/fr/cnrsinfo/...

aquitaine.cnrs.fr

Un financement européen pour changer de regard sur le langage des cellules végétales

Le Conseil européen de la recherche a annoncé ce jour la liste des lauréats des bourses ERC Advanced Grant, récompensant des scientifiques confirmés p

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Christophe 🔬 Leterrier @christlet.bsky.social · 29/06/2026

Why not go 3/3 with Anna Brachet and team from @iins-bordeaux.bsky.social. Spectrin rings in dendritic spines, mixed ßII/ßIII-tetramers, MINFLUX images! Also a talk at the Cell Biology of the Neuron GRC: www.biorxiv.org/content/10.6...

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Bordeaux Neurocampus @neurobordeaux.bsky.social · 16/06/2026

Our conference BrainStress will take place on 14-16 October. Mind the deadlines for abstract submission and early-bird registration! July 1st! brainstress.sciencesconf.org

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Saravanan Palani @syncellbiolab.bsky.social · 12/06/2026

Our new paper in @plosbiology.org introduces IntAct-U-ExM enabling isoform-specific imaging of actin at nanoscale across yeast, mammalian cells & primary neurons. Fabulous work spearheaded by @anubhavdhar.bsky.social along with an amazing team! #actin #U-ExM journals.plos.org/plosbiology/...

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Monica_BIC @monica-bic.bsky.social · 27/01/2026

Catching actin waves... do you know more about this phenomena? Contact me, please!

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German BioImaging @gerbi-gmb.de · 11/06/2026

Call for Workshops: TiM2027! Expert in microscopy, image analysis, or AI? Propose a workshop for Trends in Microscopy 2027! ✅ Hands-on learning ✅ Access to labs & industry gear ✅ Network with researchers 📅 Deadline: June 30, 2026 🔗 Apply: t1p.de/zxwxx #TiM2027 #Microscopy #BioImaging

t1p.de

Workshops - German BioImaging

Photo credits: Thomas Blank Information for Workshop Providers GerBI-GMB invites proposals for scientific and educational workshops for TiM2027. The workshop submission deadline is June 30, 2026....

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Ewan Birney @ewanbirney.bsky.social · 06/05/2026

Minflux is one of the technologies pushing the boundaries of what we can see in living cells - tracking single molecules at nanometer resolution in living cells. Sounds like science fiction - is actually doable @embl - come and learn more!

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Alex Johnson @ajcellbio.bsky.social · 26/05/2026

This session will showcase some really state-of-the-art imaging techniques to look at cellular architecture (@sventruckenbrodt.bsky.social) and live, contact free biomechanics (@laurabacete.bsky.social)! Sign up below! #expansionmicroscopy #brillouin #plants 🌱🔬

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Gordon and Betty Moore Foundation @moorefound.bsky.social · 23/02/2026

Funded through our Science Program, this technique expands the scientific toolkit in ways that can reshape what researchers are able to ask and answer. New research – #ExpansionMicroscopy enlarges cells up to 60x by embedding them in a water-absorbing gel www.quantamagazine.org/expansion-mi...

quantamagazine.org

Expansion Microscopy Has Transformed How We See the Cellular World | Quanta Magazine

How physically magnifying objects using a key ingredient in diapers has opened an unprecedented view of the microbial world.

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DChoquet @danielchoquet.bsky.social · 03/06/2026

🚀 Bordeaux is accelerating biological imaging! 🧬🔬 💶 €5M invested in cutting-edge tech: 🔹 MINFLUX – track single proteins at 1–2nm, >1000 loc/sec 🔹 IMPACT – next-gen multiphoton imaging in thick tissues Bordeaux = European hub for life science innovation! 🌍✨ #BioImaging #Neuroscience

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Alan Brown @alanbrownhms.bsky.social · 22/05/2026

One, perhaps two, of our postdocs are moving on to faculty positions this year (more news soon!). While they're truly irreplaceable, it does mean that we have openings for new members to join our team studying #cilia. If interested, please apply: academicpositions.harvard.edu/postings/15526

Advert for postdoctoral positions at Harvard Medical School studying cilia

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Mark Histed @markhisted.org · 23/05/2026

Overall very cool stuff. A reconfigurable instrument that repurposes equipment investment in adaptive optics, SLM, lasers, to do a lot of different things 🧪

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Gaëlle Recher @gaellerecher.bsky.social · 18/05/2026

🔈 PhD offers! 2 PhD positions available at the BiOf-lab 🎓 Fancy 3D biology? Microscopy? Microfabrication? Bordeaux? 🧫 🔬 🛠️ 🍷 the first one is already online, the other will be out soon! (stay tuned) adum.fr/as/ed/voirpr...

adum.fr

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Deepa Rajan, PhD @deeparajan.bsky.social · 23/04/2026

How can a single cell learn without a brain? We explore this in my paper with @wallaceucsf.bsky.social! We discovered that single cells may learn using molecules similar to those that animal brains use to learn, like CaMKII. Cells can also propagate memory states to their progeny!

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