The anti-ageing response to Dietary Restriction (DR) is thought to be mechanistically ancient, reasoning from its phenotypic conservation. However, DR is implemented differently across species and evi...

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

Abstract. When altricial birds hatch, they are unable to regulate their own temperature, but by the time they fledge they are thermally independent. Early-

Analysis of the longest-lived mammal, the bowhead whale, reveals an improved ability to repair DNA breaks, mediated by high levels of cold-inducible RNA-binding protein.  &nbs...

Analysis of the longest-lived mammal, the bowhead whale, reveals an improved ability to repair DNA breaks, mediated by high levels of cold-inducible RNA-binding protein.  &nbs...

YouTube video by The University of Sheffield

In our new Understanding Ageing: Meet the Scientists series, we’ve invited experts in their field to talk about their research and what it means for each of us as we get older. You don’t need any scie...

Biological regulation is a highly intricate process and involves many layers of complexity even at the RNA level. Alternative splicing is crucial in the regulation of which components of a protein-cod...

The evolutionary biology of aging is fundamental to understanding the mechanisms of aging and how to develop anti-aging treatments. Thus far most evolutionary theory concerns the genetics of aging wit...

Dietary protein is a key regulator of metabolic health in humans and rodents. Many of the benefits of protein restriction are mediated by reduced consumption of dietary branched-chain amino acids (BCA...

imageimageDuring starvation, individual amino acid levels are thought to be relayed via distinct metabolic sensors, but how mTORC1 senses glutamine remains unclear. This study finds that GCN2 kinase acts as a unifying module in suppression of ...

Researchers assessed more than 1,000 results from fruit-fly immunity research published between 1959 and 2011. The majority of findings look verifiable.

Andersson et al. show that intestinal stem cells enriched for old mitochondria are metabolically distinct and have enhanced ability to regenerate the epithelial niche.

Aging | doi:10.18632/aging.206258. Mirre J.P. Simons

How to understand the risks of head injuries in sport – beyond the alarming headlines.

With English captions.

Macrophages are responsible for diverse and fundamental functions in vertebrates. Drosophila blood cells (haemocytes) are dominated by cells bearing a striking homology to vertebrate macrophages (plas...

The rewilding project off the West Sussex coast is celebrating its fourth anniversary.

An exciting new study from PHS, in collaboration with the Universities of Strathclyde and Edinburgh, shows that no cervical cancer cases have been detected in women vaccinated at age 12-13 since the H...

If you wish to show your support for the letter below regarding apparent inaction by the Royal Society in the face of breaches of its code of conduct by Elon Musk FRS, please sign below. I invite anyo...

The study seeks to determine whether rapamycin increases the lifespan of dogs, with the hope that it may also help extend human lives.

Join us at the Keystone Symposia on Aging: New Frontiers in Rejuvenation and Gerotherapeutics, February 2025, in Breckenridge, with field leaders!

Their urgent mission is to find out what is killing swathes of people in one of the most remote parts of the world

PhD Project - Mechanisms of alternative splicing in neurodegeneration and ageing at University of Sheffield, listed on FindAPhD.com