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Korolchuk Lab

@korolchuklab.bsky.social
2.6K followers 6.1K following 122 posts

Cell biology lab at Newcastle University, UK, molecular mechanisms of nutrient sensing and autophagy, ageing and age-related disease 🇺🇦

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Korolchuk Lab @korolchuklab.bsky.social · 27/09/2026
#Autophagy and #mTOR papers from last week, enjoy! biomed.news/bims-auttor/...
static.klipy.com
Batman Thinking: Interesting...
ALT: Batman Thinking: Interesting...
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Gavin McStay @gavinmcstay.bsky.social · 20/09/2026
you can sign up to receive weekly updates of this report by going to biomed.news/bims-auttor
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Eric Chevet @ericchevet.bsky.social · 20/09/2026
Good morning! This week's selection of articles on #proteostasis thanks to @biomednews.bsky.social -- biomed.news/bims-proteo/... Highlight: Encoded and non-genetic protein variants expand human functional proteome www.nature.com/articles/s41...
biomed.news
bims-proteo 2026-09-20 papers
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Korolchuk Lab @korolchuklab.bsky.social · 20/09/2026
#Autophagy and #mTOR papers from the past two weeks, have a look, there’s some really cool stuff! biomed.news/bims-auttor/... biomed.news/bims-auttor/...
static.klipy.com
Kid Cool
ALT: Kid Cool
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Eric Chevet @ericchevet.bsky.social · 06/09/2026
Good morning! This week's selection of articles on #proteostasis thanks to @biomednews.bsky.social -- biomed.news/bims-proteo/... Highlight: ArticleOnline nowSeptember 01, 2026 Ratiometric transcriptional activation by protein degradation www.cell.com/cell/abstrac...
biomed.news
bims-proteo 2026-09-06 papers
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Korolchuk Lab @korolchuklab.bsky.social · 06/09/2026
#Autophagy and #mTOR papers from last week, enjoy! biomed.news/bims-auttor/...
static.klipy.com
cosy reading
ALT: cosy reading
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Catalina Vasilescu, PhD @cvasilescu.bsky.social · 30/08/2026
Here is our fresh selection of papers on #Mitochondria in #Health & #Disease from last week! biomed.news/bims-mitdis/... ➡️ LRRK2 impairs the release sites of Parkinsons disease vulnerable dopa axons @biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social @mitoworld.bsky.social
Leucine-rich repeat kinase 2 impairs the release sites of Parkinson's disease vulnerable dopamine axons
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Gavin McStay @gavinmcstay.bsky.social · 30/08/2026
you can sign up to receive weekly updates on this topic by going to biomed.news/bims-auttor
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Eric Chevet @ericchevet.bsky.social · 30/08/2026
Good morning! This week selection of articles and #preprints on #proteostasis thanks to @biomednews.bsky.social -- biomed.news/bims-proteo/... Highlight: IRE1 activity is prognostic in localised and metastatic prostate cancer and affects epithelial lineage state link.springer.com/article/10.1...
biomed.news
bims-proteo 2026-08-30 papers
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Korolchuk Lab @korolchuklab.bsky.social · 30/08/2026
#Autophagy and #mTOR papers from last week, selected with the help of @biomednews.bsky.social search engine, enjoy! biomed.news/bims-auttor/...
biomed.news
bims-auttor 2026-08-30 papers
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Eric Chevet @ericchevet.bsky.social · 23/08/2026
Good morning! This week's selection of articles and #preprints on #proteostasis thanks to @biomednews.bsky.social -- biomed.news/bims-proteo/... Highlight: ER-liquid condensate contacts sequester FAM134B/C and RhoA to govern cell morphology www.sciencedirect.com/science/arti...
biomed.news
bims-proteo 2026-08-23 papers
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Korolchuk Lab @korolchuklab.bsky.social · 23/08/2026
#Autophagy and #mTOR papers from last week, enjoy! biomed.news/bims-auttor/...
static.klipy.com
Cute Green Creature Reading a Book
ALT: Cute Green Creature Reading a Book
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Eric Chevet @ericchevet.bsky.social · 16/08/2026
Good morning! This week's selection of articles on #proteostasis thanks to @biomednews.bsky.social -- biomed.news/bims-proteo/... Highlight: Chrysosplenetin-induced TMED3 aggregation triggers unfolded protein response in pancreatic cancer link.springer.com/article/10.1...
biomed.news
bims-proteo 2026-08-16 papers
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Korolchuk Lab @korolchuklab.bsky.social · 16/08/2026
#Autophagy and #mTOR papers from last week, thanks to @biomednews.bsky.social search engine. Sign up if you want hassle-free literature updates in your area. biomed.news/bims-auttor/...
static.klipy.com
Corridor Crew: Man Says 'Very Easily'
ALT: Corridor Crew: Man Says 'Very Easily'
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Korolchuk Lab @korolchuklab.bsky.social · 11/08/2026
Latest paper from our lab: Activation of pro-survival autophagy by a small molecule promoting p62 oligomerisation - Journal of Biological Chemistry www.jbc.org/article/S002...
jbc.org
Activation of pro-survival autophagy by a small molecule promoting p62 oligomerisation
Autophagy is a critical mechanism of cellular quality control, orchestrated by selective autophagy receptor (SAR) proteins. Pharmacologically enhancing the cargo-targeting capacity of SARs presents an...
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Eric Chevet @ericchevet.bsky.social · 09/08/2026
Good evening! This week's selection of articles on #proteostasis thanks to @biomednews.bsky.social -- biomed.news/bims-proteo/... Highlight: @genesdev.bsky.social RBM39 modulates UPR signaling through alternative splicing of IRE1α/ ERN1 genesdev.cshlp.org/content/earl...
biomed.news
bims-proteo 2026-08-09 papers
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Korolchuk Lab @korolchuklab.bsky.social · 09/08/2026
#Autophagy and #mTOR papers from last week, a bit quiet atm but still worth a look: biomed.news/bims-auttor/...
static.klipy.com
Good Morning: Singing in the Rain Chick
ALT: Good Morning: Singing in the Rain Chick
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Eric Chevet @ericchevet.bsky.social · 02/08/2026
Good morning! This week's selection of articles and #preprints on #proteostasis thanks to @biomednews.bsky.social -- biomed.news/bims-proteo/... Highlight: Spatiotemporal regulation of DNA repair proteins between Golgi and nucleus maintains genome stabilit rupress.org/jcb/article/...
biomed.news
bims-proteo 2026-08-02 papers
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Catalina Vasilescu, PhD @cvasilescu.bsky.social · 02/08/2026
Subscribe here biomed.news/bims-mitdis
biomed.news
Mitochondrial disorders
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Korolchuk Lab @korolchuklab.bsky.social · 02/08/2026
#Autophagy and #mTOR papers from last week, have a look! biomed.news/bims-auttor/...
static.klipy.com
Man Looks Closely with Magnifying Glass
ALT: Man Looks Closely with Magnifying Glass
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Eric Chevet @ericchevet.bsky.social · 26/07/2026
Good morning! This week's selection of articles on #proteostasis thanks to @biomednews.bsky.social -- biomed.news/bims-proteo/... Highlight: A bivalent molecular glue linking lysine acetyltransferases to oncogene-induced cell death www.cell.com/cell/abstrac...
biomed.news
bims-proteo 2026-07-26 papers
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Korolchuk Lab @korolchuklab.bsky.social · 26/07/2026
#Autophagy and #mTOR papers from last week, enjoy! biomed.news/bims-auttor/...
static.klipy.com
Science Over Fiction: Biden vs. Trump Books
ALT: Science Over Fiction: Biden vs. Trump Books
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Eric Chevet @ericchevet.bsky.social · 19/07/2026
Good morning! This week's selection of articles and #preprints on #proteostasis thanks to @biomednews.bsky.social -- biomed.news/bims-proteo/... Hihlight: Lysosomes and lysosomal dysfunction in ageing biology www.nature.com/articles/s41...
biomed.news
bims-proteo 2026-07-19 papers
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Korolchuk Lab @korolchuklab.bsky.social · 19/07/2026
#Autophagy and #mTOR papers from last week, pre-selected by @biomednews.bsky.social engine. Enjoy! biomed.news/bims-auttor/...
static.klipy.com
Jerry Chilling and Reading by the Pool
ALT: Jerry Chilling and Reading by the Pool
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Korolchuk Lab @korolchuklab.bsky.social · 12/07/2026
#Autophagy and #mTOR papers from last two weeks, have a look. Thanks @biomednews.bsky.social biomed.news/bims-auttor/... biomed.news/bims-auttor/...
static.klipy.com
Colorful Abstract Plant Cell Painting
ALT: Colorful Abstract Plant Cell Painting
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Biomed News @biomednews.bsky.social · 29/06/2026
You can subscribe to receive weekly issues of this report by going to biomed.news/bims-auttot
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Korolchuk Lab @korolchuklab.bsky.social · 28/06/2026
A month-worth of #autophagy and #mTOR publications, screened by @biomednews.bsky.social (great job as always!) and manually curated. All you need to keep in the loop is below: biomed.news/bims-auttor/... biomed.news/bims-auttor/... biomed.news/bims-auttor/... biomed.news/bims-auttor/...
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Welcome Back Students - Zhivago1955
ALT: Welcome Back Students - Zhivago1955
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Eric Chevet @ericchevet.bsky.social · 31/05/2026
Good morning! This week's selection of articles and #preprints on #proteostasis thanks to @biomednews.bsky.social -- biomed.news/bims-proteo/... Highlight: Mechanism of RACK1-dependent ZAKα activation at stalled and collided ribosomes www.sciencedirect.com/science/arti...
biomed.news
bims-proteo 2026-05-31 papers
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Catalina Vasilescu, PhD @cvasilescu.bsky.social · 31/05/2026
Absolutely great collection of papers from last week on #Mitochondria in #Health & #Disease! 📚 biomed.news/bims-mitdis/... A few highlighted topics in the comments 👇 @biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social @mito-news.bsky.social @mitoscientists.bsky.social
Image generated with AI depicting 'mitochondria in blood cells' in watercolor style.
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Korolchuk Lab @korolchuklab.bsky.social · 31/05/2026
Another great collection of #autophagy and #mTOR papers from the past two weeks, can’t be missed if you’re into these topics! biomed.news/bims-auttor/... biomed.news/bims-auttor/...
static.klipy.com
Family Guy: Stewie Griffin's 'Good Stuff'
ALT: Family Guy: Stewie Griffin's 'Good Stuff'
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Yasin Dagdas @plantophagy.bsky.social · 29/05/2026
Heidelberg University Biochemistry Center @bzh-hd.bsky.social is looking for a #professor of #biochemistry. Please spread the word‼️ www.bzh.uni-heidelberg.de
bzh.uni-heidelberg.de
Universit�t Heidelberg - BZH
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Korolchuk Lab @korolchuklab.bsky.social · 22/05/2026
A new preprint from the lab led by a talented PhD student Niall Wilson and supported by amazing collaborators Sovan Sarkar, Tetsushi Kataura, Elton Zeqiraj, G. Vignir Helgason, Ian Ganley, and Agnieszka Bronowska #AMPK is the key cellular sensor of #NAD 👇🏼👇🏼👇🏼 www.biorxiv.org/content/10.6...
biorxiv.org
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Korolchuk Lab @korolchuklab.bsky.social · 17/05/2026
There’s been lots of great science published in the past two weeks on #autophagy and #mTOR topics. Anyone with an interest in this area should look at these 👇🏼👇🏼👇🏼 biomed.news/bims-auttor/... biomed.news/bims-auttor/...
static.klipy.com
Blue Power Ranger Billy: Okay, Now That's Cool!
ALT: Blue Power Ranger Billy: Okay, Now That's Cool!
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Catalina Vasilescu, PhD @cvasilescu.bsky.social · 26/04/2026
Last week's selection of papers on #Mitochondria in #Health and #Disease biomed.news/bims-mitdis/... Accelerating Leigh syndrome drug discovery [...] in brain organoids www.nature.com/articles/s41... @gavinmcstay.bsky.social @biomednews.bsky.social @mitoscientist.bsky.social @mito-news.bsky.social
Accelerating Leigh syndrome drug discovery through deep learning screening in brain organoids
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Gabriele Zaffagnini @gzaffagnini.bsky.social · 03/05/2026
Happy Sunday! Here comes another egg-cellent issue of #cebooc: The Kitajima group is on fire, look how they discover how parental genomes compete for cytoplasm after fertilization: www.nature.com/articles/s41... Full issue: biomed.news/bims-cebooc/... Powered by @biomednews.bsky.social
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Catalina Vasilescu, PhD @cvasilescu.bsky.social · 03/05/2026
Latest research collection on #Mitochondria in #Health and #Disease! biomed.news/bims-mitdis/... Nitrogen metabolism profiling reveals cell state-specific pyrimidine synthesis pathway choice www.nature.com/articles/s42... @biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social
Nitrogen metabolism profiling reveals cell state-specific pyrimidine synthesis pathway choice
https://www.nature.com/articles/s42255-026-01520-0
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Eric Chevet @ericchevet.bsky.social · 03/05/2026
Good morning!! This week's selection of articles and #preprints on #proteostasis thanks to @biomednews.bsky.social -- biomed.news/bims-proteo/... Highlight: A network-based map of the chemical exposome connects molecular interactions to public health www.nature.com/articles/s41...
biomed.news
bims-proteo 2026-05-03 papers
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Korolchuk Lab @korolchuklab.bsky.social · 03/05/2026
#Autophagy and #mTOR papers from last week, enjoy! biomed.news/bims-auttor/...
media.tenor.com
a bird is sitting on a tree branch with an umbrella .
ALT: a bird is sitting on a tree branch with an umbrella .
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Korolchuk Lab @korolchuklab.bsky.social · 30/04/2026
Gordon Research Conference on Thiol-Based Redox Regulation and Signaling is still open to registration, link below 👇 👇 👇 www.grc.org/thiol-based-... This highly anticipated meeting bridges Redox Chemistry to Biology, Aging and Disease will take place in July 12-17 2026. Travel grants coming!
grc.org
2026 Thiol-Based Redox Regulation and Signaling Conference GRC
The 2026 Gordon Research Conference on Thiol-Based Redox Regulation and Signaling will be held in Castelldefels, Barcelona Spain. Apply today to reserve your spot.
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Korolchuk Lab @korolchuklab.bsky.social · 29/04/2026
We have a fully-funded PhD studentship (UK candidates only) to work on #autophagy of protein aggregates in the context of #Parkinson's and #Lewy Body Disease. Application through the link below. RTs appreciated! www.findaphd.com/phds/project...
findaphd.com
Molecular mechanisms of α-synuclein aggrephagy and their dysregulation during human ageing at Newcastle University on FindAPhD.com
PhD Project - Molecular mechanisms of α-synuclein aggrephagy and their dysregulation during human ageing at Newcastle University, listed on FindAPhD.com
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Korolchuk Lab @korolchuklab.bsky.social · 26/04/2026
My son is raising money for @msf.ca. Please help by donating and spreading the word 🙏🏻 www.justgiving.com/page/ivan-ko...
justgiving.com
100km Ultramarathon for Medical Care in Crisis Zones
Help Ivan Korolchuk raise money to support Medecins Sans Frontieres / Doctors Without Borders (MSF)
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Gabriele Zaffagnini @gzaffagnini.bsky.social · 26/04/2026
Happy Sunday! Here comes another spectacular issue of #cebooc! Highlight: unlike drosophila, mouse germ cells do not squeeze their cytoplasm in the oocyte-to-be pubmed.ncbi.nlm.nih.gov/42014922/ Read the full issue here: biomed.news/bims-cebooc/... Powered by @biomednews.bsky.social
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Eric Chevet @ericchevet.bsky.social · 26/04/2026
Good Morning!! This week's selection of articles on #proteostasis thanks to @biomednews.bsky.social -- biomed.news/bims-proteo/... Highlight: An inhibitor of GCN2 and the integrated stress response directly targets ZAK protein kinase to limit cytotoxicity www.jbc.org/article/S002...
biomed.news
bims-proteo 2026-04-26 papers
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asofiahcosta.bsky.social @asofiahcosta.bsky.social · 25/04/2026
It's been a minute... Two new issues of the most recent analytical and computational advances in #metabolomics, #smallmolecule, and #lipidomics analyses. biomed.news/bims-metlip/... biomed.news/bims-metlip/... A collaboration with @biomednews.bsky.social
media.tenor.com
a book called 6 language visual dictionary sits on a shelf with other books
ALT: a book called 6 language visual dictionary sits on a shelf with other books
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Korolchuk Lab @korolchuklab.bsky.social · 26/04/2026
#Autophagy and #mTOR papers from last week, have a look! biomed.news/bims-auttor/...
media.tenor.com
a black and white image of a cartoon character with big eyes and the words let 's take a look
ALT: a black and white image of a cartoon character with big eyes and the words let 's take a look
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asofiahcosta.bsky.social @asofiahcosta.bsky.social · 05/04/2026
Happy Easter! Don't miss the latest publications on computational and analytical methods for #metabolomics and #lipidomics biomed.news/bims-metlip/... Pre-sorted by @biomednews.bsky.social
media.tenor.com
a cartoon of snoopy holding an easter egg with the words happy easter below him .
ALT: a cartoon of snoopy holding an easter egg with the words happy easter below him .
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Catalina Vasilescu, PhD @cvasilescu.bsky.social · 19/04/2026
Last 2 weeks of research on #Mitochondria in #Health and #Disease! 📚 biomed.news/bims-mitdis/... biomed.news/bims-mitdis/... Among highlights 👇 www.nature.com/articles/s41... @biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social
nature.com
Cell-type-targeted mitochondrial transplantation rescues cell degeneration - Nature
MitoCatch is a cell-type-specific mitochondrion-targeting system that links mitochondria and the cell surface by protein binders and delivers mitochondria into the target cell.
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Gabriele Zaffagnini @gzaffagnini.bsky.social · 19/04/2026
Happy Sunday! It has been another fantastic week for our beloved #oocytes! The streak on CPLs continues with this awesome work from Miguel Leung: pubmed.ncbi.nlm.nih.gov/41986725/! Full issue here: biomed.news/bims-cebooc/... Thanks @biomednews.bsky.social for preselecting.
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Korolchuk Lab @korolchuklab.bsky.social · 19/04/2026
Plenty to chose from in the lists of #Autophagy and #mTOR papers published last two weeks, enjoy! biomed.news/bims-auttor/... biomed.news/bims-auttor/...
media.tenor.com
a man in a polo shirt says " a lot "
ALT: a man in a polo shirt says " a lot "
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Catalina Vasilescu, PhD @cvasilescu.bsky.social · 05/04/2026
Easter edition of #Mitochondria in #Health and #Disease! 🐰🐣 biomed.news/bims-mitdis/... @gavinmcstay.bsky.social @mitoscientist.bsky.social @biomednews.bsky.social @mitoscientists.bsky.social Perling drives mtDNA nucleoid distribution www.science.org/doi/10.1126/...
science.org
Pearling drives mitochondrial DNA nucleoid distribution
The distribution of mitochondrial DNA–containing nucleoids is essential for mitochondrial function and genome inheritance; however, no known mechanisms can explain nucleoid segregation or their regula...
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