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American Aging Association

@americanaging.bsky.social
594 followers 180 following 342 posts

The official Bluesky account of AGE. #geroscience #aging #AGE2025 www.americanagingassociation.org

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American Aging Association @americanaging.bsky.social · 29/09/2026
400 people with diabetes, tracked 14 days: more glucose variability (within safe range) was linked to BETTER next-day quality of life, not worse. Researchers say chasing a perfectly flat blood sugar line may itself be a hidden burden 🩸 www.sciencedaily.com/releases/202...
sciencedaily.com
Diabetes study finds keeping blood sugar too steady may come at a price
People with diabetes reported better quality of life after days when their glucose stayed largely within a healthy range, even when levels fluctuated more than usual. The unexpected finding suggests t...
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American Aging Association @americanaging.bsky.social · 27/09/2026
Stanford researchers who build biological age clocks are urging caution on commercial tests: no FDA approval as diagnostics, ~3 years of built-in error per Dr. Rehkopf, and even rapamycin (proven in animals) shows confusing signals on human clocks 🧬🔬 med.stanford.edu/news/insight...
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American Aging Association @americanaging.bsky.social · 25/09/2026
Calling AGE trainees! LRC's Fall 2026 Journal Club on Epigenetics & Aging kicks off week of Oct 12 — 3 biweekly sessions, present just 1 key figure, open to grad students/postdocs/early-career researchers everywhere 🧬📚 Sign up: docs.google.com/forms/d/e/1F... #AGETrainees #GeroScience
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American Aging Association @americanaging.bsky.social · 23/09/2026
A review of 350+ studies — co-authored by 2026 AGE award winner Bailey Knopf — finds eating LESS protein may improve metabolism and extend lifespan in sedentary adults. Active people still need it. eurekalert.org/news-releases/1137190 #AGE2026
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American Aging Association @americanaging.bsky.social · 22/09/2026
One brain protein, many signs of aging. Restoring "Menin" in old mice improved memory, bone density, and skin thickness all at once. Mouse research, but a striking single biological switch. sciencedaily.com/releases/2026/09/260918000437.htm #AgingResearch #AGE2026
sciencedaily.com
Scientists restore a brain protein and reverse signs of aging in mice
Scientists found that declining levels of the brain protein Menin may help drive aging, with lower levels in mice linked to inflammation, cognitive decline, weaker bones, and thinner skin. Restoring M...
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American Aging Association @americanaging.bsky.social · 20/09/2026
A liver hormone called Hepassocin drops with age in mice AND humans. Without it, aged mice barely survive liver injury (40% vs 87%). Restoring it reversed liver aging and rescued survival. nature.com/articles/s41392-026-02773-7 #AgingResearch #AGE2026
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American Aging Association @americanaging.bsky.social · 20/09/2026
An AI-designed lung drug had an unexpected side effect: 6 aging clocks all found lower biological age in treated patients, peaking at week 4. Early, small-scale evidence — not proof of reversal. insilico.com/news/rnt0709261-rentosertib-proteomic-aging-clocks #AGE2026
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American Aging Association @americanaging.bsky.social · 17/09/2026
Laurence Maeyens (UT Health San Antonio) has 3 honors in 2 years: 2025 AGE Poster Pitch Award, 2026 AGE Trainee Travel Award, and a 2026 BSRA Travel Award to represent AGE at Oxford. His work: androgens & the male longevity gap. linkedin.com/in/laurencemaeyens #AGE2026
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American Aging Association @americanaging.bsky.social · 15/09/2026
New study from UC Berkeley (NIH-funded): semaglutide extended lifespan in older mice and outperformed calorie restriction on some measures (memory, blood sugar) even when food intake was matched 🐭🧬 Mouse study only — doesn't show human lifespan extension. www.sciencedaily.com/releases/202...
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Reposted by American Aging Association
Dog Aging Project @dogagingproject.bsky.social · 14/09/2026
Want to help dogs live longer, healthier lives? Join the Dog Aging Project Pack at dogagingproject.org! 🐾Together, we can help dogs live longer, healthier lives. #PackSpotlight #Dogs #CommunityScience
Pack Spotlight: Pack Member Senna, a black-and-white dog wearing a pink party hat on green artificial turf, holding colorful number balloons shaped like 1 and 3 in front of its face. Text below reads: Pack Member #1,860 - join the pack at dogagingproject.org
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American Aging Association @americanaging.bsky.social · 14/09/2026
UCLA study, ~1,500 adults, 3 cohorts: built a "Brain Aging Index" from resting brain scans. Older-looking brains = worse memory/executive function + more depressive symptoms, even in young/midlife adults. Gut bacteria linked to the effect. www.thelancet.com/journals/ebi... #BrainHealth #GeroScience
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Reposted by American Aging Association
British Society for Research on Ageing @bsrageing.bsky.social · 11/09/2026
Always great to host the @americanaging.bsky.social best ECR presentation as part of the BSRA-AGE longstanding relationship. Who will win the Korenchevsky Prize and represent the BSRA as our best ECR speaker at AGE 2027? Find out at prizegiving at the end of day 3!
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American Aging Association @americanaging.bsky.social · 12/09/2026
Maria Branyas lived to 117 — the longest-lived person recorded. A new study found she had BOTH extreme aging markers (short telomeres) AND protective traits (low inflammation, younger epigenetic age). sciencedaily.com/releases/2026/09/260909231800.htm #AGE2026
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American Aging Association @americanaging.bsky.social · 09/09/2026
Sea squirts are unusually rich in plasmalogens — a lipid that declines with age. Fed to aged mice: faster learning, healthier brain synapses, less inflammation, even darker regrown hair 🐙🧠 Animal study only, but a wild new angle on brain aging. doi.org/10.3389/fmol... #GeroScience #BrainHealth
doi.org
Frontiers | Plasmalogens Eliminate Aging-Associated Synaptic Defects and Microglia-Mediated Neuroinflammation in Mice
Neurodegeneration is a pathological condition in which nervous system or neuron losses its structure, function, or both leading to progressive neural degener...
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American Aging Association @americanaging.bsky.social · 07/09/2026
This Labor Day, honoring the researchers and clinicians across geroscience working every day toward more healthy years for the aging community 🔬🧬 Thank you for the work. Happy Labor Day from AGE. #LaborDay #GeroScience #AmericanAgingAssociation
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American Aging Association @americanaging.bsky.social · 06/09/2026
New cell research: SIRT1 protects the genome by blocking "jumping genes" (LINE-1) from copying themselves elsewhere — a mechanistic clue behind a decade of sirtuin longevity research. Cell-based only so far, not yet in animals/people. lifespan.io/a-mechanisti... #GeroScience #HallmarksOfAging
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American Aging Association @americanaging.bsky.social · 06/09/2026
New findings from the The Dog Aging Project examined blood metabolites from dogs across the country and found metabolic patterns tied to lifespan that closely mirror biomarkers already linked to human aging. Source: www.sciencedaily.com/releases/202... #GeroScience
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American Aging Association @americanaging.bsky.social · 04/09/2026
Congrats to Dr. Yang Yeh winner of a 2026 AGE Poster Pitches Award. A postdoctoral fellow in Dr. Dudley Lamming's Metabolism of Aging lab at the University of Wisconsin Madison. Nearly 20 publications, NIH K99/R00-funded, studying metabolism's role in aging & Alzheimer's.
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American Aging Association @americanaging.bsky.social · 02/09/2026
Congrats to Laurence Maeyens a PhD student in Biology of Aging at UT Health San Antonio for wining 2026 Trainee Travel Award AND 2025 AGE Poster Pitch Award winner. His research spans hormone timing and fat tissue's role in the male longevity gap.
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American Aging Association @americanaging.bsky.social · 31/08/2026
Congratulations to Roberto Santin Marquez of the Oklahoma Medical Research Foundation, winner of the 2026 Paul F. Glenn Award. His research explores how a hormone-signaling pathway affects metabolism differently in males and females. #AgingResearch #Geroscience #AGE2026
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American Aging Association @americanaging.bsky.social · 29/08/2026
Congrats to Caitlyn Smith- #UniversityOfKentucky, winner of the 2026 Walter R. Nicolai Award for her research on sex differences in age-related immune inflammation in adipose tissue. Read more: medicine.uky.edu/users/csm277 americanagingassociation.org/awards #AGE2026
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American Aging Association @americanaging.bsky.social · 27/08/2026
Your "biological age" test result depends on which lab you use. Even the scientist who invented epigenetic clocks admits there's no shared standard yet. The biology's real — the hype's ahead of it. ncbi.nlm.nih.gov/pmc/articles/PMC12905613 #AGE2026 #Biolog icalAge
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American Aging Association @americanaging.bsky.social · 25/08/2026
Adele Finch of Brown University and the Buck Institute for Research on Aging took home both a 2026 Poster Pitches Award and an Early Career Scholar Travel Award. Her research explores how brain cells clear out damaged mitochondria to stay healthy. #BrainHealth #AgingResearch #AGE2026
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American Aging Association @americanaging.bsky.social · 23/08/2026
Congratulations to Laura Quijano Sarraga of the Oklahoma Medical Research Foundation, who earned both a 2026 Data Blitz Award and an Early Career Scholar Travel Award. Learn more: americanagingassociation.org/awards #AgingResearch #WomenInSTEM #AGE2026
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American Aging Association @americanaging.bsky.social · 22/08/2026
Your DNA mutates every day. Repair slows with age → mutations pile up → some cell populations start to take over. A 2024 GeroScience review tracked this in blood stem cells. This is hallmark #1: genomic instability. 🔗 link.springer.com/article/10.1007/s11357-024-01374-y #HallmarksOfAging #AGE2026
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American Aging Association @americanaging.bsky.social · 20/08/2026
Double win for Rola Zeidan (Univ. of Florida) at AGE 2026: Data Blitz Award + Early Career Scholar honor for her work on iron biomarkers and muscle decline. americanagingassociation.org/awards #AGE2026
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American Aging Association @americanaging.bsky.social · 19/08/2026
Double win for Helene Martini (Mayo Clinic) at AGE 2026: Poster Pitches Award + Early Career Scholar for her research on mitochondria and senescent "zombie cells." americanagingassociation.org/awards #AGE2026
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American Aging Association @americanaging.bsky.social · 17/08/2026
Your heart, brain & liver may each be aging at different rates. A 2026 Nature Aging paper built organ-specific biological age clocks to measure exactly that. nature.com/articles/s43587-026-01113-2 #BiologicalAge #AGE2026
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American Aging Association @americanaging.bsky.social · 14/08/2026
Your DNA repair systems slow with age — letting damage accumulate. A 2025 Nature Reviews Drug Discovery paper argues we may soon be able to "supercharge" DNA repair to slow aging. Hallmark #1. pubmed.ncbi.nlm.nih.gov/40506534/ #HallmarksOfAging #AGE2026
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American Aging Association @americanaging.bsky.social · 13/08/2026
Spotlight: Hannah Ampofo (UNT Health Science Center), 2026 Early Career Scholar. Blocking blood flow in one neck artery injures BOTH sides of the aging brain in mice — a new angle on cognitive decline. americanagingassociation.org/2026-age-early-career-scholars #AGE2026
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American Aging Association @americanaging.bsky.social · 13/08/2026
New PLOS Digital Health study: "retinal biological age" from routine eye scans predicted future osteoporosis risk over a decade of follow-up. Non-invasive equipment doctors already use, catching bone decline early. medicalxpress.com/news/2026-05... #GeroScience #BiologicalAge #Osteoporosis
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American Aging Association @americanaging.bsky.social · 11/08/2026
PEARL trial (114 adults, 48 wks): rapamycin missed its main goal (visceral fat). But women on the 10mg dose saw real gains in lean muscle & less pain — not seen in men 💊 Honest science: one miss, one real signal. www.aging-us.com/article/2062... #GeroScience #Rapamycin #AgingResearch
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American Aging Association @americanaging.bsky.social · 09/08/2026
The most-cited framework in aging research: 12 "hallmarks of aging," from genomic instability to cellular senescence to chronic inflammation — each a real target for intervention. doi.org/10.1016/j.ce... #HallmarksOfAging #GeroScience #Longevity
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American Aging Association @americanaging.bsky.social · 08/08/2026
CALERIE-2, the first controlled human CR trial: cutting calories by just 14% over 2 years regrew part of the thymus & boosted fresh T cell output 🧬 Researchers found a gene (PLA2G7) that may explain why. www.sciencedaily.com/releases/202... #GeroScience #ImmuneAging #AgingResearch
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American Aging Association @americanaging.bsky.social · 31/07/2026
Research to Impact: Building Science Communications is a free program designed for emerging investigators in aging biology, offered by @nathanshockcenters.org and @afar.org. 📅 Deadline to apply: August 7 nathanshockcenters.org/nsc-research-to-impact-building-science-communications-program
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American Aging Association @americanaging.bsky.social · 29/07/2026
New Nature Aging framework mapped 2,358 aging genes onto the human protein network, screened 6,442 existing drugs, and found 370 that could affect aging hallmarks — 21 pro-longevity, 23 age-accelerating. A systematic map, not a cure. www.nature.com/articles/s43... #GeroScience #Longevity
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American Aging Association @americanaging.bsky.social · 27/07/2026
Buck Institute trial: therapeutic plasma exchange + immunoglobulin reduced biological age by an average of 2.6 years, measured across DNA methylation & immune markers 🧬 People with poorer baseline health saw the biggest gains. www.buckinstitute.org/news/clinica... #GeroScience #BiologicalAge
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American Aging Association @americanaging.bsky.social · 19/07/2026
25,000+ women tracked 25 years: closely following a Mediterranean diet = 23% lower risk of dying from any cause 🫒 (JAMA Network Open) www.health.harvard.edu/heart-health... #MediterraneanDiet #Longevity #Nutrition
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American Aging Association @americanaging.bsky.social · 16/07/2026
New Nature Aging study: it's not just your epigenetic age that predicts survival — it's how fast it's changing. Accelerating biological age = higher mortality risk, regardless of starting point 🧬⏱️ #EpigeneticClock #Longevity #AgingResearch
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American Aging Association @americanaging.bsky.social · 16/07/2026
Good news for the under-slept: UK Biobank study of ~84,000 adults found moderate weekend "catch-up sleep" (1-1.5 hrs) was linked to LOWER dementia risk 😴 Recovery may matter. www.ncbi.nlm.nih.gov/pmc/articles... #SleepHealth #Dementia #BrainHealth
ncbi.nlm.nih.gov
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American Aging Association @americanaging.bsky.social · 16/07/2026
Myth bust: massive BMJ meta-analysis (69 trials, ~154K older adults) found calcium + vitamin D offer NO meaningful fall/fracture protection for most people 💊 Strength training matters more. www.medicaldaily.com/calcium-vita... #BoneHealth #MythBusted
medicaldaily.com
BMJ Meta-Analysis of 154,000 People: Calcium and Vitamin D Supplements Offer Little Meaningful Bone Protection for Most Older Adults
BMJ meta-analysis of 69 trials and 153,902 adults June 15, 2026: calcium, vitamin D, or both offer no meaningful fracture or fall protection for most older adults.
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American Aging Association @americanaging.bsky.social · 14/07/2026
Social connection = a mortality risk factor. New meta-analysis: loneliness raises death risk 14%, social isolation 35%, living alone 21% 🤝 Relationships aren't just nice — they're medicine. www.ncbi.nlm.nih.gov/pmc/articles... #SocialConnection #HealthyAging
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American Aging Association @americanaging.bsky.social · 14/07/2026
Massive meta-analysis (482K dementia cases): hearing loss shows a clear dose-response link to dementia risk — the worse the hearing, the higher the risk 👂 Getting it treated may protect your brain. www.ncbi.nlm.nih.gov/pmc/articles... #BrainHealth #Dementia #HearingLoss
ncbi.nlm.nih.gov
Hearing Loss and Risk of Dementia: A Burden of Proof Study
Hearing loss is a significant public health concern, which we estimate in the Global Burden of Disease (GBD) study impacts over one billion or 65% of adults aged 55 and older. The Lancet Commission id...
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American Aging Association @americanaging.bsky.social · 14/07/2026
25,000+ women tracked 25 years: closely following a Mediterranean diet = 23% lower risk of dying from any cause 🫒 (JAMA Network Open) www.health.harvard.edu/heart-health... #MediterraneanDiet #Longevity #Nutrition
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American Aging Association @americanaging.bsky.social · 10/07/2026
Why does fasting extend lifespan? A 2026 Nature Comm study found it's about how efficiently cells shut off lipid-burning after a fast — get that right, lifespan jumps 60%+ in worms 🔬 doi.org/10.1038/s414... #Longevity #Fasting #AgingResearch
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American Aging Association @americanaging.bsky.social · 10/07/2026
Landmark study of 9,000+ people: as we age, our gut microbiomes become more unique to us — and the people with the MOST distinctive microbiomes lived longer & healthier 🦠 pubmed.ncbi.nlm.nih.gov/33619379/ #GutHealth #Microbiome #Longevity
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American Aging Association @americanaging.bsky.social · 10/07/2026
Early human trials (SToMP-AD, STAMINA) tested senolytic drugs in older adults to clear "zombie cells" linked to brain inflammation & Alzheimer's. Early days, but a hot research front 🧠 www.ncbi.nlm.nih.gov/pmc/articles... #AlzheimersResearch #Senolytics #GeroScience
ncbi.nlm.nih.gov
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American Aging Association @americanaging.bsky.social · 09/07/2026
2026 pilot study: 13 weeks of spermidine improved vaccine antibody responses in adults 65+ by reversing signs of immune cell aging 💉 Especially helped people who initially responded poorly. onlinelibrary.wiley.com/doi/full/10.... #ImmuneHealth #HealthyAging #GeroScience
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American Aging Association @americanaging.bsky.social · 07/07/2026
New Nature Aging study: it's not just your epigenetic age that predicts survival — it's how fast it's changing over time. Accelerating biological age = higher mortality risk, regardless of starting point 🧬⏱️ www.nature.com/articles/s43... #EpigeneticClock #BiologicalAge #Longevity
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American Aging Association @americanaging.bsky.social · 07/07/2026
5,400+ women 63+, tracked for years: stronger grip = 15% lower death risk per 7kg increase. Faster chair stands = 9% lower risk per 6 sec improvement. Independent of activity level 💪 www.health.harvard.edu/bones-and-jo... #Longevity #StrengthTraining #HealthyAging #MuscleMatters
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