iiinova — where your digital self keeps evolving

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Matthew Dowd @matthewjdowd.bsky.social · 3h

Latest WSJ poll: "63% want to pause AI development 61% want a billionaire wealth tax 59% want Medicare for All 57% want a $20 minimum wage 58% want to end U.S. military aid to Israel" This is the center of the country politically. it is time all adjust to this political spectrum, esp. media.

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Mike Johansen @mikejohansenmd.medsky.social · 2h

I wonder if the non-sense political attacks over the last 20 years will become less effective in the age of disinformation.

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David W (aka Flex NP) @rnflex.bsky.social · 15h

Add liver cirrhosis and by extension liver transplant to this in the next few years as well with the rise of multi agonist GLP1/GIP and/or glucagon drugs. Obesity related cancers as well over the longer term(20 years)

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Swapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 15h

100% David We talk about 4 pillars for treatment of diabetic kidney disease If we get G-force on time (+/- a flozin) that’s the only pillar you need!

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Mike Johansen @mikejohansenmd.medsky.social · 15h

It is hard to overstate the significance of these. It's essentially modern life antibiotics. Just mind bending.

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Swapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 16h

And others which were booming - like - sleep apnea/CPAP - knee replacements - Dialysis Will also slow down We are already seeing slowdowns in dialysis growth

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Mike Johansen @mikejohansenmd.medsky.social · 20h

Reviews we absolutely don't need x100.

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Mike Johansen @mikejohansenmd.medsky.social · 23h

Bariatric surgery is the modern example of ulcer surgery from decades ago. Its going to go extinct in rapid order.

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David W (aka Flex NP) @rnflex.bsky.social · 30/09/2026

Worried about blood sugar because it contains glucagon? Worry not and laugh again @mikejohansenmd.medsky.social ending fasting glucose was ~100. Fasting insulin dropped 45% !!!! As noted 40% of 9mg/12mg ended up in diabetic remission HOMA IR dropped >50% again.

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Mike Johansen @mikejohansenmd.medsky.social · 30/09/2026

I've had enough heartfelt requests to last a lifetime.

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Mike Johansen @mikejohansenmd.medsky.social · 30/09/2026

🤩 so good the diabetes and prediabetes levels just went away.

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Ed @notdred.bsky.social · 29/09/2026

I think one thing that the MAHA-friendly people of the world do not appreciate is how terrible it is for you to have viruses invade and then live in your body

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Aaron Rupar @atrupar.com · 29/09/2026

🤡 Schmitt beclowns himself 🤡 Schmitt concocted an elaborate conspiracy theory that Smith traveled to Atl for a Hawks game and to collude with Fani Willis, & flashed his "evidence" before accusing Smith of perjury. There's just one problem -- his facts were totally wrong. Here's the whole sequence:

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Mike Johansen @mikejohansenmd.medsky.social · 29/09/2026

If interested; look at how the leaners shake out in this. If this is what actually occurs; 👀.

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Julian Reif @julianreif.bsky.social · 28/09/2026

It's starting www.nber.org/system/files...

nber.org

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Mike Johansen @mikejohansenmd.medsky.social · 27/09/2026

I love that systematic reviews are the top of the evience pyramid b/c someone made a figure. 😂

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Mike Johansen @mikejohansenmd.medsky.social · 25/09/2026

I strongly support increasing the correlation between wackadoodle and RFK Jr.

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Ron Filipkowski @ronfilipkowski.bsky.social · 23/09/2026

This guy constantly makes himself look foolish. bsky.app/profile/fact...

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Mike Johansen @mikejohansenmd.medsky.social · 23/09/2026

At times you read a trial and think; holy mackeral. The older literature likely just underestimated the treatment effect b/c they included lesser meds. Atorva/rosuva are ridiculously beneficial for human health. www.nejm.org/doi/full/10....

nejm.org

Atorvastatin, Cardiovascular Events, and Disability-free Survival in Older Adults | NEJM

The effectiveness and safety of statins for the primary prevention of cardiovascular events and the extension of disability-free survival among older adults remain uncertain. We conducted a double-...

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Mike Johansen @mikejohansenmd.medsky.social · 23/09/2026

Reading an rct and want an estimand. Only 2/3rds of patients actually taking the medication.

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jamelle @jamellebouie.net · 22/09/2026

this is a genuinely crazy story

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Mike Johansen @mikejohansenmd.medsky.social · 22/09/2026

Says to things to me: 1. Sociology wins (i.e. group behavior) 2. Need to create structures to allow the sociology to win

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Adam Kucharski @adamjkucharski.bsky.social · 21/09/2026

I suspect we’ll increasing see a return to “you can only submit if you know an insider” systems, like the old-school PNAS ‘contributed’ track. It’s a bit like we’re already seeing with the new ArXiv ‘endorsement’ system...

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Micah @rincewind.run · 21/09/2026

congratulations to everyone on reinventing Worse Cable

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Steve M. @stevemnomoremister.bsky.social · 19/09/2026

He's really good at this.

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Mike Johansen @mikejohansenmd.medsky.social · 18/09/2026

Fwiw: likelihood of ai blowing the world up <<<< likelihood of human relying on ai blowing the world up.

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Mike Johansen @mikejohansenmd.medsky.social · 18/09/2026

D's would do better if all their consultants became barristas.

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Mike Johansen @mikejohansenmd.medsky.social · 17/09/2026

There is clearly a dearth of specialist led guidelines. 😂

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Mike Johansen @mikejohansenmd.medsky.social · 17/09/2026

The idea that you can reconstruct a governmental panel and assume it remains relevant is comical.

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Katie Martin @katie0martin.ft.com · 16/09/2026

superb trolling, no notes

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Christopher Mims @mims.bsky.social · 16/09/2026

Good news everyone: AI is *not* going to kill us all! But don't take my word for it -- I talked to (real) experts, and dug deep into the logic of an "AI apocalypse" and found it wanting. That doesn't mean AI companies are off the hook, though. (gift link) www.wsj.com/tech/ai/ai-a...

wsj.com

Forget the AI Apocalypse—the Real Threats Are Already Here

Airplanes, elevators and restaurants all have regulations to ensure their safe operation. Many experts argue for similar conventional measures for AI.

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Christopher Mims @mims.bsky.social · 16/09/2026

this is, increasingly, my area of expertise, and you’re right to be skeptical

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CIDRAP @cidrap.bsky.social · 15/09/2026

New polls highlight tumbling trust in measles vaccine safety, advice from doctors In total, 76% of Americans said they trusted the measles vaccine for kids, down from 84% six years ago. Read more: bit.ly/4yEXP8W

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David Ho @davidho.bsky.social · 15/09/2026

NSF has reduced the research budget for all atmospheric, ocean, and earth sciences by ~80%. 80%! A lot of us will not be conducting new research or training new students for the foreseeable future.

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LeCaffeinated @thetirednurse.bsky.social · 16/09/2026

Hey if you’re a physician in Ohio and you’re a member of this organization, please leave it.

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Swapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 15/09/2026

It’s official - EASiKidney - one of the largest kidney trials at ~ 15000 is terminated early www.boehringer-ingelheim.com/human-health... A setback for ASI in CKD (they are going strong in hypertension of course)

boehringer-ingelheim.com

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Joe Bak-Coleman @jbakcoleman.bsky.social · 15/09/2026

I was pretty chuffed about science when the doctors at NYU figured out why my face had gone numb and I had lost the ability to speak and swallow. They turned to the scientific literature, which guided them through keeping me from dying from a rare disorder and regaining the ability to speak and eat.

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Mike Johansen @mikejohansenmd.medsky.social · 15/09/2026

IMHO: this has been pretty obv for a long time. People having medical care coverage is good for everyone.

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Kieran Healy @kjhealy.co · 15/09/2026

This is partly an LLM problem and partly an organizational problem. The LLM makes life much, much easier for everyone who wants to just pretend, and much, much harder for everyone who doesn’t.

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Zach Weinersmith @zachweinersmith.bsky.social · 15/09/2026

Can we please stop doing this? I made a comic about it and everything!

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