Vaughn Cooper @vscooper.micropopbio.org · 8hI like Once Upon a Time in Hollywood more with each watch 140
Reposted by Vaughn CooperIgnacio Gallup-Diaz @igallupd.bsky.social · 12h"A 20-year-old Amish woman with leukemia got measles and died in Pa.’s largest outbreak in three decades: After measles swept through her household, the young woman wanted to get vaccinated. Her doctor said she couldn't because she had leukemia and the treatments had weakened her immune system."share.inquirer.comA 20-year-old Amish woman with leukemia got measles and died in Pa.’s largest outbreak in three decadesAfter measles swept through her household, the young woman wanted to get vaccinated. Her doctor said she couldn't because she had leukemia and the treatments had weakened her immune system. 34017
Reposted by Vaughn CooperAlisa Bokulich @alisabokulich.bsky.social · 23hHistory Dept @ University of Texas Austin invites applications for a TT assistant professor, specializing in modern history of science, technology, & medicine. Committee will consider applicants who specialize in any scientific practice in any part of the world since 1600. Deadline Nov 30 #HPSnetworks.h-net.orgThe University of Texas at Austin - Assistant Professor (TT) – History of Science, Technology, and Medicine | H-NetPreferred qualifications include research and teaching records that will complement one or more of the department’s strengths including: African History, Asian History, British History, Digital Humanities, Latin American History, U.S. History, and related fields. 33130
Reposted by Vaughn CooperNigel Goldenfeld @nigelgoldenfeld.bsky.social · 10h🧪 "Mr. Trump’s science adviser, Michael Kratsios, has criticized the agency’s system for deciding which grants to fund ... He also argued the N.S.F. should ... bypass external review panels.” Kratsios lost 90% of assets while CFO of Clarium Capital. Do you trust him with the US science portfolio?nytimes.comNational Science Foundation Diverted $1.4 Billion in Science Funds Mandated by CongressThe move, affecting about one-fifth of the National Science Foundation’s primary research budget, is the latest sign of how the White House is asserting more control over grants. 13020
Reposted by Vaughn CooperCosta Samaras @costasamaras.com · 9hIf they can ignore Congress and not spend 20% of the funds Congress told them to invest the country’s science capabilities, than all involved have lost the justification to remain in a position of public trust. 14316
Reposted by Vaughn CooperFrog and Toad Bot @frogandtoadbot.bsky.social · 9hToad did not answer. He had fallen asleep. 213820
Reposted by Vaughn CooperSasha Gusev @sashagusevposts.bsky.social · 01/10/2026A searchable mapping between NIH study sections and program officers that doesn't suck. (Claude one-shot) sashagusev.github.io/po-study-sec... 33716
Vaughn Cooper @vscooper.micropopbio.org · 01/10/2026Enlightening synopsis, like a free minireview. Especially appreciate the graphic of the selection shadow for those of us in evolutionary medicine #EvMed 020
Reposted by Vaughn CooperEric Topol @erictopol.bsky.social · 30/09/2026Why do our cells age? It's not just wear and tear, accumulated damage. Loss of cell identity takes center stage. A new Nature paper and connection with prior work that substantially advances the science of aging. In the new Ground Truths. erictopol.substack.com/p/loss-of-ce...erictopol.substack.comLoss of Cell Identity Drives Human AgingThat’s What Biological (Epigenetic) Aging Clocks Are Measuring 817250
Reposted by Vaughn CooperCraig MacLean @craigmaclean.bsky.social · 30/09/2026Postdoc position available in my group to work on ERC funded project on evolutionary biology of antibiotic resistance. Looking for someone with expertise in bacterial genetics, AMR, and evolutionary biology. www.jobs.ac.uk/job/DSZ416/p...jobs.ac.ukPostdoctoral Research Associate at University of OxfordExplore an exciting academic career as a Postdoctoral Research Associate. Don't miss out on other academic jobs. Click to apply and explore more opportunities. 24477
Reposted by Vaughn CooperVivek Mutalik @vivekmutalik.bsky.social · 29/09/2026In our brand new 🥳 review, @hemaa-selvakumar.bsky.social & team pull a scattered literature in phage biology into a coherent framework for scaling up to engineering complex communities. We poured our hearts into this to share challenges & future opportunities for the nextGen! 22913
Reposted by Vaughn CooperJosh Marshall @joshtpm.bsky.social · 29/09/2026Best Sen Schmitt meme yet 857587
Reposted by Vaughn CooperCarl Zimmer @carlzimmer.com · 28/09/2026The human genome is part virus. And here's a virus that's part human, having picked up a human gene about 100,000 years ago. My story here: nyti.ms/4hRKNPCnyti.msThis Virus Stole a Human Gene and Won’t Let Go of It (Gift Article)Scientists have found a human gene lurking in a virus that causes skin infections. It may be using our own DNA to infect us. 518052
Vaughn Cooper @vscooper.micropopbio.org · 27/09/2026We believe these findings show that bacterial evolution during chronic infections can follow predictable pathways that drive disease progression, which we hope can enable earlier detection, monitoring, and treatment (with Abx or phage!) of CF lung infections. Paper: www.biorxiv.org/content/10.6...biorxiv.orgConvergent genetic evolution within Burkholderia multivorans chronic infections correlates with lung function decline in cystic fibrosis patientsThe patterns and pathways of pathogen adaptation during chronic infections can reveal the gateways microbes must unlock to colonize and persist. In chronic lung infections of cystic fibrosis (CF) pati... 020
Vaughn Cooper @vscooper.micropopbio.org · 27/09/2026As various bacterial phenotypes changed in concert, due to common regulatory mutations, so too did the pattern of diversification AND the decline of lung function. Drivers of chronicity spawned several enduring lineages and the patient's health suffered. 100
Vaughn Cooper @vscooper.micropopbio.org · 27/09/2026We were stunned by the convergent evolution by different strains in each patient. In total, 108 genes acquired parallel mutations indicating common host selection. 55 genes had ≥4 independent mutations! Each infection gained a combination of 5 of the most frequent, like a winning hand of cards. 232
Vaughn Cooper @vscooper.micropopbio.org · 27/09/2026Led by Leonilde Moreira with 🤩 work by Mirela Ferreira, who visited us a few years go, we combine sequencing, lots of phenotyping, and host lung function data over 7-17 years per patient. @jameszlosnik.bsky.social Importantly, phylogenetic reconstructions show which mutations drive later success 100
Vaughn Cooper @vscooper.micropopbio.org · 27/09/2026How do Burkholderia multivorans bacteria adaptively evolve during infections of the cystic fibrosis airway? A longtime collab and intensive study of 8 patients links bacterial adaptations to disease progression. Our findings also unite prior studies. www.biorxiv.org/content/10.6...biorxiv.orgConvergent genetic evolution within Burkholderia multivorans chronic infections correlates with lung function decline in cystic fibrosis patientsThe patterns and pathways of pathogen adaptation during chronic infections can reveal the gateways microbes must unlock to colonize and persist. In chronic lung infections of cystic fibrosis (CF) pati... 14521
Reposted by Vaughn CooperThe Ferrari Lab @theferrarilab.bsky.social · 27/09/2026TT Assistant Professor position in Ecology and Evolution of Infectious Disease at University of Floridaexplore.jobs.ufl.eduUniversity of Florida - Details - Assistant Professor of Biology 11435
Vaughn Cooper @vscooper.micropopbio.org · 27/09/2026Brilliant. And haunting as I’ve already begun replacing some boards 130
Reposted by Vaughn CooperC. Brandon Ogbunu @cbo.bsky.social · 27/09/2026In my latest for @undark.org, I compare AI adoption in science to the Ship of Theseus: "If you swap out every wooden plank on a ship over time, is it still the same vessel?" I argue that science derives authority from something more than data generation + publication. undark.org/2026/09/25/o...undark.orgAI Presents Science with a ‘Ship of Theseus’ ProblemOpinion | AI can replace each part of the scientific process, leaving the enterprise recognizable but devoid of human judgment. 58446
Reposted by Vaughn CooperKathleen Bachynski @bachynski.bsky.social · 27/09/2026“Studying Paulinella, scientists hope, will elucidate one of the most fundamental transitions in the history of life on our planet — and possibly give clues to how it might happen elsewhere in the universe. It could also provide practical insights on how to engineer photosynthetic organisms”nytimes.comIn an $80 Motel Room, a Discovery to Shed Light on the Origins of LifeA scrappy science project led to a significant discovery: two new species of a rare organism that could elucidate a fundamental transition in the history of life on our planet. 35119
Reposted by Vaughn CooperEric Topol @erictopol.bsky.social · 27/09/2026The word of the day: Zombified www.nytimes.com/2026/09/26/h... 711233
Reposted by Vaughn CooperCraig Kaplan @triggerloop.bsky.social · 25/09/2026It is the case. The Biosketch has a certification so that happens when you generate the document. They updated the current certification to expire Sept 26. So you need new one 147
Vaughn Cooper @vscooper.micropopbio.org · 25/09/2026FYI to everyone submitting this October NIH cycle You need to re-certify your ScienCV AFTER Sept 26 (tomorrow) for your application or it may not be accepted. Great timing! 78592
Reposted by Vaughn CooperPLOS Biology @plosbiology.org · 25/09/2026#PhageTherapy can fail when the immune system makes antibodies against therapeutic viruses. This study shows that fiber- and nozzle-specific antibodies block phage infection and promote aggregation-driven, Fc receptor-independent phagocytosis. 🧪 #ImmuneSky #structure #virus buff.ly/J0FOg9g 174
Reposted by Vaughn CooperKate Baker @ksbakes.bsky.social · 25/09/2026We have an open Assistant/Associate Professor position in Pathogen Biology at the Department of Genetics - come and join us! 🦠 🧫 🧬https://www.cam.ac.uk/jobs/assistantassociate-professor-in-pathogen-genetics-pc51175cam.ac.ukAssistant/Associate Professor in Pathogen GeneticsApplications are invited for an Assistant or Associate Professorship in Pathogen Genetics to be held in the Department of Genetics. We are searching for a talented individual with a track record of fu... 03970
Reposted by Vaughn CooperNPR @npr.org · 24/09/2026Stories of science funding being cut, labs shutting down and scientists losing jobs have flooded the media under Trump's administration. These six graphics show how those changes have affected U.S. biomedical research. n.pr/4ycseLJn.prUnder Trump, NIH funding disruptions have evolved. Here's what the numbers showStories of science funding being cut, labs shutting down and scientists losing jobs have flooded the media under Trump's administration. These six graphics show how those changes have affected U.S. biomedical research. 7213153
Reposted by Vaughn CooperJoshua Weitz @joshuasweitz.bsky.social · 25/09/2026FAI provides a window into a conservative re-imagining of science, one that might sound like it is focused on flourishing, but starts with vitriol and animus towards the very people who have driven US science forward and whose goal is the politicization of research (with a preferred winner). 155
Reposted by Vaughn CooperJoshua Weitz @joshuasweitz.bsky.social · 25/09/2026He is not alone. Amidst 1.5+ years of attacks on science, there is well-funded, ascendant support for justifying the dismantling of America's leading scientific institutions from groups who will tell you, unmoored from evidence, that NIH, NSF, etc. were so flawed, that there was only one option. 124
Reposted by Vaughn CooperErin Hotchkiss @fluvialbenthos.bsky.social · 24/09/2026We (Biological Sciences at Virginia Tech) are #hiring TWO tenure-track Molecular Microbiology professors! Review of applications starts 1 Nov. I'm happy to answer questions about the department, VT, life in Blacksburg, etc.! More info / to apply: jobs.apply.vt.edu/jobs/assista... 🧪👩🔬🦠 #academicjobsjobs.apply.vt.eduAssistant/Associate Professor - Blacksburg, Virginia, United StatesJob Description The Department of Biological Sciences in the College of Science at Virginia Tech seeks applicants for two (2) tenure-track research and teaching positions at the Assistant/Associate ... 03348
Vaughn Cooper @vscooper.micropopbio.org · 23/09/2026<shots fired> Why are consensus reviews authored by field leaders published in for-profit journals, instead of those run by the societies that serve those fields (and may have sponsored the workshop)? Disclosure: I’m a middle author of at least one, and it burns me. 2289
Vaughn Cooper @vscooper.micropopbio.org · 23/09/2026Fantastic, comprehensive, useful review if you care about RNA modifications in bacteria: @asm.org @csdetweiler.bsky.social journals.asm.org/doi/10.1128/...journals.asm.orgCompendium of RNA modifications for bacterial stress adaptation | Microbiology and Molecular Biology ReviewsSUMMARYRNA modifications in the tRNA, rRNA, and mRNA constitute a widespread layer of post-transcriptional gene regulation, commonly known as the epitranscriptome. In bacteria, tRNA and rRNA modificat... 12711
Reposted by Vaughn CooperHarmit Singh Malik @harmitmalik.bsky.social · 21/09/2026Thanks to the generosity of the Bezos Family Foundation, @basicsci.fredhutch.org is excited to announce a new search to recruit a Bezos Family Distinguished Scholar : apply.interfolio.com/193655apply.interfolio.com Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio 13731
Reposted by Vaughn Coopertracey depellegrin @traceydepellegrin.bsky.social · 21/09/2026The @c4lifesciences.bsky.social is seeking an Executive Director. CLS is a terrific group of engaged scientific & scholarly society leaders. Check out the position (ideal for a person experienced in policy & advocacy + Capitol Hill) & share w/interested, qualified folks.ascb.applytojob.comExecutive Director, Coalition for the Life Sciences - American Society for Cell Biology (ASCB) - Career PageApply to Executive Director, Coalition for the Life Sciences at American Society for Cell Biology (ASCB) in Bethesda, MD. 027
Reposted by Vaughn CooperMozammel Hoque @mozammel.bsky.social · 20/09/20261/ New paper out in ISME Communications now in full version. Bacteria rarely live alone in nature, so we ran a 6-month evolution experiment asking what happens when species are forced to share the same biofilm. Turns out, company changes everything. 🧵 doi.org/10.1093/isme...doi.orgMixed-species interactions constrain diversification and shape biofilm evolutionAbstract. Experimental evolution provides a powerful framework for dissecting how ecological interactions shape adaptive trajectories. Here, we evolved Kle 23513
Reposted by Vaughn CooperMozammel Hoque @mozammel.bsky.social · 20/09/20265/ Personal note, this is my first paper as last author, from my time at AIMI, UTS. Great collaboration with @vscooper.micropopbio.org, and huge thanks to my supervisors Diane McDougald and Scott Rice for their mentorship. This work was supported by the ARC. @arc-gov-au.bsky.social 131
Vaughn Cooper @vscooper.micropopbio.org · 20/09/2026Now published from a fun collaboration, please see 🧵 academic.oup.com/ismecommun/a...academic.oup.comMixed-species interactions constrain diversification and shape biofilm evolutionAbstract. Experimental evolution provides a powerful framework for dissecting how ecological interactions shape adaptive trajectories. Here, we evolved Kle 03921
Reposted by Vaughn CooperÁkos T Kovács @evolvedbiofilm.bsky.social · 19/09/2026Mixed-species interactions constrain diversification and shape biofilm evolution Klebsiella pneumoniae + Pseudomonas protegens + Pseudomonas aeruginosa in ISME Communications from Mozammel Hoque, with Diane McDougald, Scott Rice, @vscooper.micropopbio.org academic.oup.com/ismecommun/a... 055
Reposted by Vaughn CooperCarl Zimmer @carlzimmer.com · 17/09/2026I wrote about what came before CRISPR 4 billion years ago: a war among viruses. Gift link: nyti.ms/3TBq4q0nyti.msThe Next Gene-Editing Technology May Also Be the Oldest (Gift Article)Scientists have discovered a powerful gene-targeting system in viruses. Billions of years old, VIPR seems to predate CRISPR and may be even more powerful. 114351
Reposted by Vaughn CooperCarl Zimmer @carlzimmer.com · 17/09/2026Pennsylvania measles outbreak now up to 731 cases and 4 deaths www.pa.gov/agencies/hea...pa.govMeaslesMeasles is a disease that spreads easily from person to person and can make you sick. People who are not vaccinated are at the highest risk. The best protection against measles is vaccination. DOH is ... 45223
Reposted by Vaughn CooperDavid Ho @davidho.bsky.social · 15/09/2026NSF has reduced the research budget for all atmospheric, ocean, and earth sciences by ~80%. 80%! A lot of us will not be conducting new research or training new students for the foreseeable future. 201444722
Vaughn Cooper @vscooper.micropopbio.org · 17/09/2026www.ce-strategy.com/the-brief/gr...ce-strategy.comGrowth | Clarke & EspositoPublishers appear to be doing just fine despite AI fears. Two associations run into member backlash for very different reasons. 100
Reposted by Vaughn CooperVaughn Cooper @vscooper.micropopbio.org · 21/12/2023Friends don't let friends publish in MDPI journals. Pass it on. For more info, check out the Wikipedia page: en.wikipedia.org/wiki/MDPI 🔥en.wikipedia.orgMDPI - Wikipedia 36031
Reposted by Vaughn CooperAsher Leeks @asherleeks.bsky.social · 16/09/2026Come work with @viromehunter.bsky.social and myself at UBC! We have a postdoctoral position available for someone with an interest in bioinformatics and genomics, using sociovirology to understand disease dynamics in plant viruses. Advert: ppvlab.sites.olt.ubc.ca/files/2026/0...ppvlab.sites.olt.ubc.caBrowser Verification | UBC Cybersecurity 02635
Reposted by Vaughn CooperNature Microbiology @natmicrobiol.nature.com · 16/09/2026Out Now! Prophage-encoding engineered bacteria enable prophylactic lytic phage therapy for enteric infection in mice #MicroSkygo.nature.comProphage-encoding engineered bacteria enable prophylactic lytic phage therapy for enteric infection in miceNature Microbiology, Published online: 16 September 2026; doi:10.1038/s41564-026-02484-3An engineered non-pathogenic bacterium produces lytic phages and is protective in mouse models of Salmonella infection. 02817
Vaughn Cooper @vscooper.micropopbio.org · 16/09/2026Authors!🚨 While you scramble for scarce $ 🤔 “Springer Nature reports revenue growth of 6.2%..and adjusted operating profit growth of 7.7%. They reported even more stunning submission growth of 30% and published article growth of 13%.” Publishing in society journals helps YOU not them👇🏻. Pass it on.static.klipy.comMan Lying on a Pile of MoneyALT: Man Lying on a Pile of Money 410371
Reposted by Vaughn CooperHiten Madhani @hitenmadhani.bsky.social · 16/09/2026Spot on piece about the relationship between Federally funded science and the development of therapies. Investors want ‘de-risked’ assets. It’s their favorite word. 0102