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meisellab.bsky.social

@meisellab.bsky.social
89 followers 70 following 21 posts

Associate Professor, Dept. Immunology, University of Pittsburgh; scientist, athlete, mom 👦🐈

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Pitt Program in Microbiology & Immunology @pitt-pmi.bsky.social · 31/07/2026
Congratulations to PMI student @catmphelps.bsky.social from the @meisellab.bsky.social on her upcoming PhD thesis defense! 🙌 🎉
Catherine Phelps will present her thesis defense entitled "Mechanisms of microbiome-mediated improvements to anticancer immunity" on August 6, 2026 at 10 am at The Assembly.
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Reinhard Hinterleitner @rh-lab.bsky.social · 16/07/2026
I’m truly honored and deeply grateful to receive the Young Investigator Award from the SMI. Thanks to my mentors, collaborators, trainees, and everyone who has supported our work. I’m excited to continue exploring how the intestinal microbiome shapes mucosal immunity.
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Pitt Department of Immunology @pitt-immunology.bsky.social · 15/07/2026
Congratulations to Victor S. Cortez & @catmphelps.bsky.social, grad student in the @meisellab.bsky.social, on receiving awards from @cytokinesociety.bsky.social. They will both give talks at #Cytokines2026. Read more: www.immunology.pitt.edu/news/pitt-im...
Victor S. Cortez, assistant professor of immunology, has been awarded the  2026 Cytokine Society-Regeneron New Investigator Award for Excellence in Cytokine & Interferon ResearchCatherine Phelps, a graduate student in Marlies Meisel's lab, has been awarded The Cytokine Society's 2026 Sidney & Joan Pestka Graduate Award
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Elizabeth McKenna @elizsmckenna.bsky.social · 29/06/2026
Now in Cancer Discovery @aacrjournals.bsky.social: Tumor Microbial Burden Drives Immune Responses via Regulation of Interferon Signaling - by Haoyue Liu, Jeong-Hoon Jang, Fuduan Peng, Hajar Rajaei, @linghua-wang.bsky.social , Luis Diaz, Florencia McAllister, and colleagues doi.org/10.1158/2159...
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Pitt Department of Immunology @pitt-immunology.bsky.social · 21/05/2026
New review in @cp-immunity.bsky.social by @meisellab.bsky.social & @pitt-pmi.bsky.social ‬grad student @catmphelps.bsky.social synthesizes how exercise reshapes the immune system & the potential of exercise-based therapies for cancer, autoimmunity, and other diseases. www.cell.com/immunity/ful...
Circular diagram depicting current evidence for the mechanisms by which exercise affects the immune system in the contexts of cancer, diabetes, and experimental autoimmune encephalomyelitis.
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Pitt Department of Immunology @pitt-immunology.bsky.social · 19/03/2026
👀Ex-eye-ting research from Anthony St. Leger, associate professor of @pittophthalmology.bsky.social and @pitt-immunology.bsky.social! He and his team have developed a "living eye drop" that uses a genetically modified eye bacterium to boost healing. Read more: www.upmc.com/media/news/0...
upmc.com
Pitt Scientists Engineer “Living Eye Drop” to Support Corneal Healing
Pitt Scientists Engineer “Living Eye Drop” to Support Corneal Healing
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meisellab.bsky.social @meisellab.bsky.social · 12/03/2026
Toward a consensus on the tumor microbiota: Evidence, standards, and interpretation: Cancer Cell www.cell.com/cancer-cell/...
cell.com
Toward a consensus on the tumor microbiota: Evidence, standards, and interpretation
Tumors across diverse organs harbor microbial communities that can shape cancer biology and therapeutic responses, yet the field remains polarized by technical and interpretive challenges. In this com...
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Pitt Department of Immunology @pitt-immunology.bsky.social · 02/03/2026
Learn more about Dr. Gottschalk bit.ly/4bj0TOU, Dr. Hinterleitner bit.ly/3OCSr4o, and Dr. Meisel bit.ly/4aWO9MA (2/2)
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Pitt Department of Immunology @pitt-immunology.bsky.social · 02/03/2026
Good things come in threes! Please join us in congratulating @gottschalklab.bsky.social, @rh-lab.bsky.social, and @meisellab.bsky.social on promotion to associate professor! (1/2)
Graphic announcing Dr. Rachel Gottschalk's promotion to associate professorGraphic announcing Dr. Reinhard Hinterleitner's promotion to associate professorGraphic announcing Dr. Marlies Meisel's promotion to associate professor
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Pitt Department of Immunology @pitt-immunology.bsky.social · 25/02/2026
What is gut health? A new consensus statement in @natrevgastrohep.nature.com , co-authored by @meisellab.bsky.social, finally defines it—and outlines a framework for research and clinical practice. Read it here: www.nature.com/articles/s41...
Image of Nature Reviews Gastroenterology & Hepatology paper, "The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of gut health," by Maria L. Marco, Marla Cunningham, Stephan C. Bischoff, Gerard Clarke, Nathalie Delzenne, James D. Lewis, Marlies Meisel, Daniel Merenstein, Paul W. O'Toole, Heidi M. Staudacher, Hania Szajewska, Jerry M. Wells, and Eamonn M. M. Quigley.
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Med - a Cell Press journal @cp-med.bsky.social · 02/12/2025
We're excited to host a distinguished lineup of speakers at @CellSymposia #CSHallmarks2026, including keynote speakers @johannajoyce.bsky.social & Faisal Mahmood @harvardmed.bsky.social. View the full speaker lineup: dlvr.it/TPbBpQ
Cell Symposia: Hallmarks of cancer
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Eric Topol @erictopol.bsky.social · 21/01/2026
Physical activity and the reduction of all-cause mortality, from 2 very large prospective cohorts 1. The relationship is non-linear, suggesting a threshold effect for many types of exercise as seen below
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Cell - a Cell Press journal @cp-cell.bsky.social · 02/12/2025
We're excited to host a distinguished lineup of speakers at @CellSymposia #CSHallmarks2026, including keynote speakers @johannajoyce.bsky.social & Faisal Mahmood @harvardmed.bsky.social. View the full speaker lineup: dlvr.it/TPbBpk
Cell Symposia: Hallmarks of cancer
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Waggoner Lab @labwaggoner.bsky.social · 14/10/2025
Preview @cp-immunity.bsky.social Cutting the Gordian knot: Untangling gasdermin C from pyroptosis www.cell.com/immunity/ful... on www.cell.com/immunity/ful...
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meisellab.bsky.social @meisellab.bsky.social · 03/10/2025
Thanks for highlighting our work!
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Pitt Department of Immunology @pitt-immunology.bsky.social · 24/09/2025
Congrats, @catmphelps.bsky.social !
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Pitt Program in Microbiology & Immunology @pitt-pmi.bsky.social · 24/09/2025
Congratulations to PMI student @catmphelps.bsky.social who is the recipient of the 23rd Stephen L. Phillips Scientific Achievement award for a Pitt School of Medicine graduate student who authored the best peer-review scientific journal author this year!
Catherine Phelps!
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Open Box Science @openboxscience.bsky.social · 28/08/2025
🔬 OBS Seminar Shaping CD8+ T Cell Response Through Microbiota Metabolites 🗣️ Joseph Stevens @cincyresearch.bsky.social @cincykidsallergyim.bsky.social 🗣️@catmphelps.bsky.social @meisellab.bsky.social 🗓️ Thu, September 4th, 11 AM EDT, 3 pm GMT, 5 pm CET 👇 us02web.zoom.us/meeting/regi...
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Nature Reviews Cancer @natrevcancer.nature.com · 05/08/2025
#ResearchHighlight In a study published in #Cell, Phelps et al. find a mechanism connecting exercise, gut microbiota & anti-tumour immunity; exercise induces microbiota to produce formate, which in turn enhances CD8+ T cell functionality. 👇
nature.com
No strain, no formate gains - Nature Reviews Cancer
In a study published in Cell, Phelps et al. find a mechanism connecting exercise, gut microbiota and anti-tumour immunity; exercise induces microbiota to produce formate, which in turn enhances CD8+ T cell functionality.
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meisellab.bsky.social @meisellab.bsky.social · 22/07/2025
Congratulations to the team! Excited to see the study in print!!
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Reinhard Hinterleitner @rh-lab.bsky.social · 22/07/2025
Excited to share our new publication in collaboration with Yi-Nan Gong: Gasdermin C cleavage by Cathepsin S modulates Rab7 vesicles in intestinal epithelial cells to amplify anti-helminth immunity: Immunity www.cell.com/immunity/ful...
cell.com
Gasdermin C cleavage by Cathepsin S modulates Rab7 vesicles in intestinal epithelial cells to amplify anti-helminth immunity
Pandey et al. identify Cathepsin S (CTSS) as the direct protease that cleaves Gasdermin C (GsdmC) in the intestine. Type 2 immune-promoting microbes trigger CTSS-dependent GsdmC activation in intestin...
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The American Association of Immunologists @aai.org · 15/07/2025
AAI Members in the News! For her grad thesis with Dr. Marlies Meisel at ‪@pittdeptofmed.bsky.social‬, ‪@catmphelps.bsky.social‬ showed how #exercise improves #cancer outcomes and enhances the response to #immunotherapy in mice by reshaping the gut #microbiome 🔗 www.medschool.pitt.edu/news/gut-mic...
Headshots of Dr. Marlies Meisel and Catherine Phelps side by side.
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meisellab.bsky.social @meisellab.bsky.social · 11/07/2025
Thanks @nature.com for highlighting our recent study #exercise #microbiota #cancer
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New Scientist @newscientist.com · 09/07/2025
Exercise seems to help prevent cancer and reduce the growth of tumours, but until now, we didn’t know why. The key seems to lie in the gut’s microbiome.
newscientist.com
Exercise helps fight cancer – and we may finally know why
Exercise seems to help prevent cancer and reduce the growth of tumours, and that protective effect may be due to the way working out changes the gut microbiome
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Waggoner Lab @labwaggoner.bsky.social · 10/07/2025
Exercise enhances antitumor immunity and immunotherapy effectiveness by increasing microbiota-derived formate, which boosts CD8 T cell function and may serve as a biomarker of melanoma suppression @cellcellpress.bsky.social @catmphelps.bsky.social @meisellab.bsky.social www.cell.com/cell/fulltex...
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Adriana Forero @adforu.bsky.social · 10/07/2025
📄🧫🔬🐭What are you reading this weekend? Check out @catmphelps.bsky.social, @meisellab.bsky.social, et al’s brand new work! #H2P
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meisellab.bsky.social @meisellab.bsky.social · 10/07/2025
www.upmc.com/media/news/0...
upmc.com
Gut Microbes Key to Understanding How Exercise Boosts Cancer Immunity
Gut Microbes Key to Understanding How Exercise Boosts Cancer Immunity
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Cell - a Cell Press journal @cp-cell.bsky.social · 09/07/2025
Now online! Exercise-induced microbiota metabolite enhances CD8 T cell antitumor immunity promoting immunotherapy efficacy
dlvr.it
Exercise-induced microbiota metabolite enhances CD8 T cell antitumor immunity promoting immunotherapy efficacy
Exercise enhances antitumor immunity and immunotherapy effectiveness by increasing microbiota-derived formate, which boosts CD8 T cell function and may serve as a biomarker of melanoma suppression.
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Catherine Phelps @catmphelps.bsky.social · 09/07/2025
I am BEYOND excited to share that my PhD thesis research is officially published in @cellpress.bsky.social today. Read on for an exciting story about how #exercise promotes antitumor #immunity by modulating behavior of the #microbiome 🏃‍♀️🦠 authors.elsevier.com/c/1lPCrL7PXu...
authors.elsevier.com
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Eric Topol @erictopol.bsky.social · 09/07/2025
How exercise works through the gut microbiome to enhance response to cancer immunotherapy www.cell.com/cell/fulltex... @cellpress.bsky.social
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meisellab.bsky.social @meisellab.bsky.social · 09/07/2025
Our lab just completed a +6 year #marathon, describing for the first time that the #microbiome is critical for #exercise - induced increases in antitumor CD8 T cell immunity and improved of #cancer #immunotherapy. www.cell.com/cell/fulltex...
cell.com
Exercise-induced microbiota metabolite enhances CD8 T cell antitumor immunity promoting immunotherapy efficacy
Exercise enhances antitumor immunity and immunotherapy effectiveness by increasing microbiota-derived formate, which boosts CD8 T cell function and may serve as a biomarker of melanoma suppression.
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The New York Times @nytimes.com · 02/06/2025
A first-of-its kind study adds powerful new evidence to research showing that exercise improves cancer survival. Here's what the trial, in people treated for colon cancer, showed.
trib.al
Exercise Extends Life for People With Cancer, Study Shows
The trial, in people treated for colon cancer, showed clear evidence that an exercise program lowered the risk of disease recurrence and death.
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Eric Topol @erictopol.bsky.social · 01/06/2025
The remarkable benefit of exercise was just extended to improved survival after cancer in a randomized trial @nejm.org nejm.org/doi/full/10....
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meisellab.bsky.social @meisellab.bsky.social · 05/05/2025
not posting much these days…but this is just too positive not to share- 2 of my trainees (current) Catherine (@Catmphelps.bsky.social) and (former) Mackenzie received the AAI Trainee Achievement Award! Could not be prouder…#WomeninSTEM
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Barbara Marte @barbmarte.bsky.social · 01/05/2025
also a new N&V www.nature.com/articles/d41...
nature.com
Microbial molecule of ageing gut nudges blood stem cells towards cancer
The risk of developing blood cancer increases with age. The finding that a molecule from gut bacteria plays a part points to new ways to intervene.
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Catherine Phelps @catmphelps.bsky.social · 27/04/2025
Having a great time at #AACR25 in Chicago! Join me Sunday afternoon at the Overcoming Tumor Immune Suppression Minisymposium where I'll be discussing new @meisellab.bsky.social research on #exercise, #microbiome, and cancer immunity🏃 #WICR #WomenInSTEM
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Jacob T. Levy @jacobtlevy.bsky.social · 19/03/2025
Excellent excellent excellent from Princeton president and constitutional/ political theorist Chris Eisgruber. There's been far too little of this kind of thing; here's hoping others follow his good example. www.theatlantic.com/ideas/archiv...
theatlantic.com
The Cost of the Government’s Attack on Columbia
American universities have given the country prosperity and security. The Trump administration’s attack on academic freedom endangers all of that.
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Nature @nature.com · 13/03/2025
Some scientists in the United States have told Nature that they are considering leaving the country in the wake of widespread disruption to research brought in by the Trump administration Are you thinking about leaving? go.nature.com/424ejK8
go.nature.com
These frustrated scientists want to leave the United States – do you? Take Nature’s poll
In the wake of the Trump administration’s funding freezes and job cuts, some researchers are planning their next move.
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Julian A Nowogrodzki @plantnerd.bsky.social · 07/03/2025
🚨🧪 We’ve been talking to scientists at rallies today across the country in DC, Boston, Seattle, and NJ. Here’s why scientists are “Dismayed, depressed, disgusted” and what they’re doing about it 🧵 ⤵️ for more #StandUpforScience #StandUpforScience2025 @nature.com
nature.com
‘Scientists will not be silenced’: thousands protest Trump research cuts
Researchers at Stand Up for Science rallies voice defiance against the policies of US President Donald Trump’s administration.
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Stand Up for Science! @standupforscience.net · 07/03/2025
LIVE STREAM UP! m.twitch.tv/standupforsc...
image of the livestream
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Kevin Keegan @mothpotato.bsky.social · 07/03/2025
Stand Up for Science Rally in Pittsburgh
Cathedral of Learning with crowd gathered on Schenley Plaza grass in foreground
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Nature @nature.com · 05/03/2025
Six award-winning female scientists highlight women who have inspired them by pushing innovative research and creating opportunities for others go.nature.com/43n0J5R
go.nature.com
Behind every great woman in science, there’s another great woman in science
To mark International Women’s Day on 8 March, six award-winning female scientists highlight women who have inspired them by pushing innovative research and creating opportunities for others.
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Bella Rauch @rauchlab.bsky.social · 04/03/2025
@laurenrodda.bsky.social, @nicelab.bsky.social , @jnpruneda.bsky.social and I wrote an OpEd on the impacts of NIH cuts on Oregon: www.bizjournals.com/portland/new... It was signed by over 450 OHSU researchers! It’s unfortunately paywalled, DM me if you’d like a gift link or a pdf of it.
bizjournals.com
Opinion: Scientists on how NIH cuts will hurt all Oregonians. - Portland Business Journal
"These cuts will cripple biomedical research and drug development in the U.S. We should be investing more in science, not less."
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Vaughn Cooper @vscooper.micropopbio.org · 03/03/2025
Pittsburgh universities receive $840M from the NIH annually, making us one of the nation’s leading biomedical research centers. It’s part of our bedrock and it’s being undermined. www.wtae.com/article/pitt...
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Jeremy Berg @jeremymberg.bsky.social · 02/03/2025
New post with the WTAE Pittsburgh news story www.wtae.com/article/pitt...
wtae.com
Pittsburgh biomedical research funding hit hard by Trump policies, warns former NIH director
Berg explained that President Donald Trump's first tactic to halt biomedical research came with a general federal funding freeze, which a judge later reversed. His second tactic: Not updating the Fede...
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Angie Rasmussen @angierasmussen.bsky.social · 01/03/2025
Tom Maniatis coming in hot in @CellCellPress to spell out in no uncertain terms what cutting indirect cost rates to 15% will cost science. And a call to action: "A united front...is essential to preventing this devastating policy from taking effect." 💯 www.cell.com/cell/fulltex...
cell.com
Safeguarding the future of biomedical science in the United States
NIH’s abrupt decision to cap indirect cost reimbursement at 15% threatens the critical infrastructure supporting groundbreaking biomedical research in the United States. This policy jeopardizes Americ...
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Vaughn Cooper @vscooper.micropopbio.org · 26/02/2025
As of today, at least 73 study sections have not met. If they review 50 applications, plus 30 triaged, 10% funding rate = 8 grants per SS. That's 584 fundable grants on hold. Probably 5000 researchers affected in those teams composed of our best and brightest. SABOTAGE.
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Dan Kaplan @danhkaplan.bsky.social · 26/02/2025
I was scheduled for study section starting tomorrow. Everything's all done and ready to go. Just heard it's being "rescheduled." No reason given.
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International Union of Immunological Societies @iuis-online.bsky.social · 26/02/2025
We are excited to have @immunologypodcast.com as a partner for #IUIS2025! Listen to their latest podcast to hear Drs. Wilfried Ellmeier, Laurence Zitvogel, and Dan Littman discuss what to expect at the upcoming #IUIS2025 congress taking place in Vienna! Listen now: bit.ly/4jUqeB4
bit.ly
Ep. 98: "IUIS 2025: Waltzing into the Future of Immunology" Featuring Drs. Wilfried Ellmeier, Laurence Zitvogel, and Dan Littman - The Immunology Podcast
Dr. Wilfried Ellmeier is a Co-Chair of the Scientific Planning Committee at the International Union of Immunological Societies (IUIS) and Professor of Immunobiology and Head of the Institute of Immuno...
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Magdalena Skipper @magdalenaskipper.bsky.social · 25/02/2025
Inexplicably, US administration has launched an unprecedented assault on science, on research institutions & on vital international organizations & initiatives. An assault on science anywhere is an assault on science everywhere; the global community must unite 🧪 www.nature.com/articles/d41...
nature.com
Trump 2.0: an assault on science anywhere is an assault on science everywhere
US President Donald Trump is taking a wrecking ball to science and to international institutions. The global research community must take a stand against these attacks.
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