DURHAM, N.C. – The Burroughs Wellcome Fund is pleased to announce the recipients of the 2026 Investigators in the Pathogenesis of Infectious Disease (PATH) awards, recognizing assistant professor-leve...

Join us at the Keystone Symposia on Beyond Antibiotics: Emerging Strategies for Combating Bacterial Infection, May 2026, in Breckenridge, with field leaders!

Regenerative responses in salivary gland organoids after irradiation are mediated by IFN-I signaling.

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Modification of the nucleotide pool is emerging as key to innate immunity in animals, plants and bacteria. This Review explains how immune pathways conserved from bacteria to humans manipulate the nuc...

Callers to 988 used to be able to press 3 to reach counselors specially trained to help LGBTQ+ young people. The service had been reaching 70,000 people a month.

Every year, malaria evades the immune defenses of nearly 250 million people. But Samarchith “Sam” Kurup is determined to outsmart the parasite before it strikes. Now, with the Burroughs Wellcome…

AAI is deeply alarmed by the President’s proposal to drastically downsize the NIH by slashing its approximately $47 billion budget in fiscal year (FY) 2025 to just $28 billion in FY 2026.

Stat1 gain-of-function mice fail to resolve inflammation in viral infection because of insufficient early STAT4–IFN-γ responses.

Mackey et al report the transcriptional signature and phenotypic features of aneuploid Candida albicans strains which impact infection and susceptibility to environmental stimuli.

Nature Genetics - Combining functional genomic data from mouse and chicken with a synteny-based strategy identifies positionally conserved cis-regulatory elements in the absence of direct sequence...

View Ann Carol Palmenberg, Ph.D's obituary, find service dates, and sign the guestbook.

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Cyclic nucleotide GMP-AMP (cGAMP) plays a critical role in mediating the innate immune response through the cyclic GMP-AMP synthase (cGAS)-stimulator …

Antiviral signaling downstream of RIG-I–like receptors (RLRs) proceeds through a multi-protein complex organized around the adaptor protein mitochondrial antiviral signaling protein (MAVS). Protein co...

Nature Immunology - Inflammasomes induce pyroptosis and, through poorly defined mechanisms, promote adaptive immune responses. High-resolution imaging of the explosive morphology of pyroptosis...

Transposable element exonization can yield functional protein isoforms as seen for primate-specific IFNAR2.

Recent or ongoing respiratory inflammation in the lung regulates antiviral immune responses to SARS-CoV-2.