Benchmarking spatially aware clustering is challenging. SACCELERATOR is an open-source, extensible framework that formalizes expert-guided spatial clustering analysis.

Github Pages for SpatialHackathon

Registration and abstract submission now open: 1st Interdisciplinary Symposium on Meta Science for Methods Research (MSMR 2026) How can we improve research on research methods? This symposium will br...

Benchmarking involves designing, running and disseminating rigorous performance assessments of methods, most often for data analysis and software tools, but the process can also be applied to experime...

Due to the costs of single-cell sequencing, sample sizes are often relatively limited, sometimes leading to poorly reproducible results. In many contexts, however, larger bulk RNAseq data is…

This study reveals how the structure and cellular morphology of human dermal afferent lymphatic vessels differ from the current, primarily mouse tissue–bas

Benchmarking, which involves collecting reference datasets and demonstrating method performance, is a requirement for the development of new computational tools, but also becomes a domain of its own t...

Spatially resolved transcriptomics (SRT) enables the investigation of mRNA expression in a spatial context. While several SRT analysis frameworks have been developed, the vast majority of them focus…

Abstract. Spatial omics allow for the molecular characterization of cells in their spatial context. Notably, the two main technological streams, imaging-ba

Spatial omics assays allow for the molecular characterisation of cells in their spatial context. Notably, the two main technological streams, imaging-based and high-throughput sequencing-based, can gi...

Spatial omics technologies have revolutionized the study of tissue architecture and cellular heterogeneity by integrating molecular profiles with spatial localization. In spatially resolved transcript...

YouTube video by Leonardo Collado Torres

Modern Benchmarking: Advancing Computational Methods in Molecular Biology is an event dedicated to bringing together researchers and students from bioinformatics, computational biology, molecular biol...

Tentative Conference Schedule

Macnair and Calini et al. analyze 632,000 snRNA-seq profiles from multiple sclerosis and control brain samples, identifying distinct cellular responses in white and gray matter. They stratify MS patients into groups based on patterns of gene expression in…

Spatial omics assays allow for the molecular characterisation of cells in their spatial context. Notably, the two main technological streams, imaging-based and high-throughput sequencing-based, can gi...

Modern Benchmarking: Advancing Computational Methods in Molecular Biology is an event dedicated to bringing together researchers and students from bioinformatics, computational biology, molecular biol...