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Reposted by @eltsovmikhail.bsky.social

Kazuhiro Maeshima @kazu-maeshima.bsky.social · 08/09/2026

Is euchromatin really “open”? 🧬 Using super-resolution imaging🔬 our new study @natgenet.nature.com reveals: Euchromatin forms condensed domains in live cells. Cohesin constrains them and prevents domain mixing for proper transcriptional insulation🚧 🔗 www.nature.com/articles/s41... (1/2)

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eltsovmikhail.bsky.social @eltsovmikhail.bsky.social · 21/07/2026

Excellent work! Particularly intrigued by the observations on nucleolus-associated heterochromatin.

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Reposted by @eltsovmikhail.bsky.social

Kazuhiro Maeshima @kazu-maeshima.bsky.social · 08/04/2026

Using single-H1 imaging and computational modeling, we show that most H1 behaves like a liquid inside chromatin domains rather than binding stably to nucleosomes as in the textbook model: www.science.org/doi/10.1126/... Congrats @masaashimazoe.bsky.social & all contributors! 🎉 2/

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eltsovmikhail.bsky.social @eltsovmikhail.bsky.social · 13/04/2026

I am not afraid to say it: this is the most fundamental advance in our understanding of chromatin structure since the zig-zag fiber model. Congratulations!

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eltsovmikhail.bsky.social @eltsovmikhail.bsky.social · 17/04/2025

A question for the experts: Can you recognize nucleosomes and linker DNA in this data? Find an updated version of our manuscript in www.biorxiv.org/content/10.1...

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