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Jamie Hanson

@jamielarsh.bsky.social
3.7K followers 2.6K following 340 posts

Psychology & Neuroscience Researcher at Pitt & LRDC | Studying the Impact of Early Life #Adversity on 🧠 Development | #Stress | Reposts ≠Endorsements

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Jamie Hanson @jamielarsh.bsky.social · 10/09/2026
More U.S. kids live in net worth poverty than income poverty, and almost no one studies it. Our new paper argues wealth deprivation shapes children's development in its own right, and that standard wealth measures miss the debts poorer families carry. academic.oup.com/cdpers/advan...
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Jamie Hanson @jamielarsh.bsky.social · 23/08/2026
Social isolation recruits amygdala-medial prefrontal cortex projections to escalate alcohol drinking in male mice www.biorxiv.org/content/10.1...
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Jamie Hanson @jamielarsh.bsky.social · 13/08/2026
I want to dig into this one more... "Historical slavery predicts contemporary disparities in mortality between Black and White Americans" www.pnas.org/doi/10.1073/...
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Jamie Hanson @jamielarsh.bsky.social · 16/07/2026
Children’s limited cognitive capacity creates a learning bottleneck that accelerates the emergence of systematic language structures, producing sequences both children and adults find easier to learn. doi.org/10.1016/j.cognition.2026.10…
Fig. 8. The relative probability of each model (power law, exponential, uniform) across generations, for each age group. Error-bars represent the 95% confidence intervals across chains. For both age groups, the relative probability of the power law model increases and surpasses the alternatives by the end of transmission.
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Reposted by Jamie Hanson
Jamie Hanson @jamielarsh.bsky.social · 26/06/2026
Socioeconomic Status and Subdivisions of the Amygdala and Hippocampus in Children and Adolescents www.sciencedirect.com/science/arti...
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Jamie Hanson @jamielarsh.bsky.social · 30/06/2026
Adverse childhood experiences are already embedded in biological systems by age nine; a threat-related aging profile emerged as a predictor of later psychiatric issues in this longitudinal study. www.sciencedirect.com/science/arti...
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Jamie Hanson @jamielarsh.bsky.social · 29/06/2026
Researchers used scans from more than 5,000 individuals to map how brain structure varies across many different cases of depression. www.nature.com/articles/s41...
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Jamie Hanson @jamielarsh.bsky.social · 26/06/2026
Socioeconomic Status and Subdivisions of the Amygdala and Hippocampus in Children and Adolescents www.sciencedirect.com/science/arti...
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Jamie Hanson @jamielarsh.bsky.social · 26/06/2026
I, honestly, feel very honored to receive this award... I read a number of papers from Dr. Reeb-Sutherland when I was starting my dissertation. She was a real trailblazer! Thanks to @isdp.org and their award selection committee!
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ACAMH - Association for Child and Adolescent Mental Health @acamh.bsky.social · 16/06/2026
What do #psychologists really mean by positive affect & why does it matter for children’s mental health? Find out in this #MindtheKids episode with @jamielarsh.bsky.social & hosts @drjanegilmour.bsky.social and @umartoseeb.bsky.social.🎧 bit.ly/4dndemi
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Jamie Hanson @jamielarsh.bsky.social · 09/06/2026
Executive function deficits are associated with various self-injurious thoughts and behaviors, according to a systematic meta-analysis of research. www.biologicalpsychiatryjournal.com/article/S000...
biologicalpsychiatryjournal.com
Executive Function and Self-Injurious Thoughts and Behaviors: A Systematic Review and Meta-Analysis
Although executive functioning deficits have been implicated in self-injurious thoughts and behaviors, the strength of their associations remain unclear. Few mechanisms reliably differentiating betwee...
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Jamie Hanson @jamielarsh.bsky.social · 04/06/2026
Primate cortex organization is governed by two opposing molecular gradient axes originating from sensory and allocortical areas www.science.org/doi/10.1126/...
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Jamie Hanson @jamielarsh.bsky.social · 03/06/2026
Monitoring heart rate while using smartphones provides insights into physiological responses during daily activities. www.nature.com/articles/s41...
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Jamie Hanson @jamielarsh.bsky.social · 03/06/2026
Disadvantaged neighborhoods correlated with lower cortical thickness and accelerated maturation rates in adolescents. doi.org/10.1093/cercor/bhaghttps://…
Figure 1 Schematic path diagram depicting latent growth models of cortical thickness and surface area development, with neighborhood characteristics as predictors of the intercept and slope of cortical devel-opment. Average age is presented at each timepoint. Double-headed arrows represent the slope and intercept variances and covariances. Numbers represent the factor loadings. ∗Factor loading was freely esti-mated. CT, cortical thickness; SA, cortical surface ar ea.Figure 2 Changes in average cortical thickness (mm) and total cortical surface area (mm2) with age for a random subsample of 3,000 participants. Average developmental trajectories fit using loess with 95% confidence intervals are presented, overlaid on spaghetti plots of individual trajectories.Figure 3 Relationship between neighborhood characteristics and individual intercept and slope values for cortical thickness (purple) and surface area (green). To support model convergence, thickness values were rescaled by multiplying by 10, and surface area values were scaled between 0 and 1. ND, neighborhood disadvantage; E O, neighborhood educational opportunity; HO, neighborhood health/environmental opportunity .
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Jamie Hanson @jamielarsh.bsky.social · 03/06/2026
I'm trying to get back into BlueSky... so here I go
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Jamie Hanson @jamielarsh.bsky.social · 02/06/2026
Working memory differences partially explain how socioeconomic status impacts academic gaps in adolescence. onlinelibrary.wiley.com/doi/full/10…
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Elvisha Dhamala @elvisha.bsky.social · 25/03/2026
Our latest work looking at the neuroanatomical basis of impulsivity in youth is out now in Molecular Psychiatry!
nature.com
Neuroanatomy reflects individual variability in impulsivity in youth - Molecular Psychiatry
Molecular Psychiatry - Neuroanatomy reflects individual variability in impulsivity in youth
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Martin Gell @martingell.bsky.social · 11/03/2026
🚨 New preprint alert! 🚨 Transdiagnostic latent factor models of psychopathology are widely assumed to improve brain-behaviour associations. So we decided to test this directly and found that they don't. A short 🧵 Link: www.biorxiv.org/content/10.6... 1/10
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Justin Wolfers @justinwolfers.bsky.social · 06/03/2026
This is not good.
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Jamie Hanson @jamielarsh.bsky.social · 02/03/2026
Sleep disorders and structural alterations in brain regions linked with motivation: a neuroimaging meta-analysis www.nature.com/articles/s41...
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Jamie Hanson @jamielarsh.bsky.social · 13/02/2026
Chatted with colleagues at @acamh.bsky.social about a recent paper... and wondered about how silly I looked... I guess I will know soon.
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Cleanthis Michael @clmich.bsky.social · 05/02/2026
Check out our new paper evaluating the performance of five brain age algorithms in two population-based cohorts of youth 🧠 @ohbmofficial.bsky.social
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Jamie Hanson @jamielarsh.bsky.social · 04/02/2026
Linking obesity with white matter microstructure highlights the importance of brainstem tracts and sex differences academic.oup.com/braincomms/a...
academic.oup.com
Linking obesity with white matter microstructure highlights the importance of brainstem tracts and sex differences
Gurholt et al. report associations between obesity and regional white matter phenotypes across commonly used diffusion magnetic resonance imaging metrics,
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Marc L Seal @parkvillegeek.bsky.social · 02/02/2026
A Systematic Evaluation of the Performance of Multiple Brain Age Algorithms in Two Cohorts of Youth onlinelibrary.wiley.com/doi/full/10....
onlinelibrary.wiley.com
A Systematic Evaluation of the Performance of Multiple Brain Age Algorithms in Two Cohorts of Youth
Performance of five influential brain age estimation algorithms in two population-based cohorts of youth. Brain age was quantified using estimates of brain structure, and performance was evaluated ba....
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Reposted by Jamie Hanson
PLOS Biology @plosbiology.org · 02/02/2026
How are energy #metabolism pathways distributed across the #cortex? @alaindagher.bsky.social &co map five pathways in the human #brain, linking metabolic organization with brain structural & functional properties, as well as developmental dynamics @plosbiology.org 🧪 plos.io/4c1JVp8
Left:  Pathways involved in brain energy metabolism. Energy metabolism refers to processes involved in energy production from nutrient molecules. Glucose is the main energy source in the brain under normal physiological conditions. Glucose entering brain cells can be utilized in three parallel pathways. It can be processed through glycolysis to produce 2 ATP and 2 pyruvate molecules (blue). Lactate dehydrogenases catalyze the interconversion of lactate and pyruvate (purple). Pyruvate is transported into mitochondria, where it enters the TCA cycle to generate high-energy electron carriers NADH and FADH2 (green), driving the complete oxidation of glucose through the mitochondrial electron transport chain (red). Glucose entering the brain can also enter the PPP. PPP is an anabolic pathway that uses glucose to produce 5-carbon sugars and NADPH, an essential co-factor used in nucleotide and lipid biosynthesis (yellow). Glucose can also be stored in the form of glycogen via glycogen synthase, a process mainly active in astrocytes. Right: Energy pathway maps. Colors show z-scored mean expression values across all genes in each pathway. ppp, pentose phosphate pathway; tca, tricarboxylic acid cycle; oxphos, oxidative phosphorylation; lactate, lactate metabolism and transport.
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Jamie Hanson @jamielarsh.bsky.social · 01/02/2026
🧠 Not all brain age algorithms are equal! In our new study, one algorithm (Pyment) outperformed other models in youth. Algorithms fail when your sample's age range is narrow or mismatched with training data. So, choose wisely... onlinelibrary.wiley.com/doi/10.1002/... #BrainAge #Neuroimaging
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Jamie Hanson @jamielarsh.bsky.social · 01/02/2026
🧠 Not all brain age algorithms are equal! In our new study, one algorithm (Pyment) outperformed other models in youth. Algorithms fail when your sample's age range is narrow or mismatched with training data. So, choose wisely... onlinelibrary.wiley.com/doi/10.1002/... #BrainAge #Neuroimaging
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Jamie Hanson @jamielarsh.bsky.social · 15/01/2026
New paper in @acamh.bsky.social's JCPP! We found that early adversity doesn't affect positive emotions uniformly-- youth follow 4 distinct developmental trajectories. & This heterogeneity matters for understanding depression/anxiety risk. 🧵 1/5 📊 Paper: acamh.onlinelibrary.wiley.com/doi/10.1111/...
acamh.onlinelibrary.wiley.com
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Jamie Hanson @jamielarsh.bsky.social · 15/01/2026
New paper in @acamh.bsky.social's JCPP! We found that early adversity doesn't affect positive emotions uniformly-- youth follow 4 distinct developmental trajectories. & This heterogeneity matters for understanding depression/anxiety risk. 🧵 1/5 📊 Paper: acamh.onlinelibrary.wiley.com/doi/10.1111/...
acamh.onlinelibrary.wiley.com
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Divyangana Rakesh @divyangana.bsky.social · 24/01/2025
In our 🚨 NEW PAPER 🚨 "Beyond the income-achievement gap: The role of individual, family, and environmental factors in cognitive resilience among low-income youth", we used machine learning to characterise predictors of cognitive resilience. acamh.onlinelibrary.wiley.com/doi/full/10....
acamh.onlinelibrary.wiley.com
JCPP Advances | ACAMH Child Development Journal | Wiley Online Library
Machine learning based prediction of cognitive resilience among low income youth.
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Jamie Hanson @jamielarsh.bsky.social · 14/01/2026
The role of the ‘word gap’ for the intergenerational transmission of education: A genetically sensitive study osf.io/preprints/ps...
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Jamie Hanson @jamielarsh.bsky.social · 14/01/2026
Synchrony between brain age and internalising and externalising symptoms across adolescence www.medrxiv.org/content/10.6...
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Jamie Hanson @jamielarsh.bsky.social · 19/12/2025
An unbiased comparison of 14 epigenetic clocks in relation to 174 incident disease outcomes www.nature.com/articles/s41...
nature.com
An unbiased comparison of 14 epigenetic clocks in relation to 174 incident disease outcomes - Nature Communications
Epigenetic clocks estimate biological age and health risks. Here, the authors compare 14 clocks in 18,859 individuals, showing second-generation clocks better predict disease incidence and mortality, ...
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Jamie Hanson @jamielarsh.bsky.social · 19/12/2025
When the science alone is not enough: embracing our responsibility as science communicators www.nature.com/articles/s41...
nature.com
When the science alone is not enough: embracing our responsibility as science communicators - Neuropsychopharmacology
Neuropsychopharmacology - When the science alone is not enough: embracing our responsibility as science communicators
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Jamie Hanson @jamielarsh.bsky.social · 04/12/2025
White matter microstructure alterations in social anxiety disorder – a mega-analysis across 12 cohorts in the ENIGMA-Anxiety Working Group www.sciencedirect.com/science/arti...
sciencedirect.com
White matter microstructure alterations in social anxiety disorder – a mega-analysis across 12 cohorts in the ENIGMA-Anxiety Working Group
Studies investigating social anxiety disorder (SAD) have reported inconsistent alterations in white matter (WM) microstructure. The ENIGMA-Anxiety Wor…
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Jamie Hanson @jamielarsh.bsky.social · 01/12/2025
Inferring intrinsic neural timescales using optimal control theory www.nature.com/articles/s41...
nature.com
Inferring intrinsic neural timescales using optimal control theory - Nature Communications
Here, the authors develop novel dynamical methods to model brain regions’ intrinsic neural timescales (INTs) from data, and find that they couple whole-brain structural connectivity to dynamic switchi...
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Jamie Hanson @jamielarsh.bsky.social · 01/12/2025
Distinct Roles of Positive and Negative Maternal Mental Health in Parenting Styles and Child Development www.sciencedirect.com/science/arti...
sciencedirect.com
Distinct Roles of Positive and Negative Maternal Mental Health in Parenting Styles and Child Development
Maternal mental health significantly impacts child development, yet the role of positive maternal mental health in shaping parenting and child outcome…
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Jamie Hanson @jamielarsh.bsky.social · 26/11/2025
Vulnerability to memory decline in aging revealed by a mega-analysis of structural brain change www.nature.com/articles/s41...
nature.com
Vulnerability to memory decline in aging revealed by a mega-analysis of structural brain change - Nature Communications
Across 13 longitudinal studies (3,737 adults), the authors show that brain atrophy parallels memory loss, with a stronger coupling in later life. APOE ε4 increases decline, yet genetic risk does not m...
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Jamie Hanson @jamielarsh.bsky.social · 24/11/2025
Google's notebookLM (notebooklm.google) generated this infographic (in ~1 min) about a recent paper: jamanetwork.com/journals/jam... It isn't perfect, but it is a solid start. It feels like lots of journals' promotions/media departments won't last long with this...
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Jamie Hanson @jamielarsh.bsky.social · 18/11/2025
Brain activity explains message effectiveness: A mega-analysis of 16 neuroimaging studies academic.oup.com/pnasnexus/ar...
academic.oup.com
Brain activity explains message effectiveness: A mega-analysis of 16 neuroimaging studies
Abstract. Persuasive communication in marketing, political, and health domains influences sales, elections, and public health. We present a mega-analysis (
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Jamie Hanson @jamielarsh.bsky.social · 17/11/2025
Childhood adversity, low positive affect and psychopathology: a meta-analytic structural equation modeling study www.nature.com/articles/s44...
nature.com
Childhood adversity, low positive affect and psychopathology: a meta-analytic structural equation modeling study - Nature Mental Health
In this meta-analytic structural equation modeling study, Stoia et al. examined whether positive affect mediates the relationship between childhood adversity and psychopathology.
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Jamie Hanson @jamielarsh.bsky.social · 17/11/2025
COVID-19-Induced School Closures and Disadvantaged Children’s Post-COVID Academic Growth: A Longitudinal Cohort Study edworkingpapers.com/sites/defaul...
edworkingpapers.com
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Jamie Hanson @jamielarsh.bsky.social · 17/11/2025
Understanding the impact of misinformation on adolescents www.nature.com/articles/s41...
nature.com
Understanding the impact of misinformation on adolescents - Nature Human Behaviour
Adolescents are especially vulnerable to misinformation but also possess unique strengths. This Perspective outlines a forward-looking research agenda to understand these vulnerabilities and foster re...
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Jamie Hanson @jamielarsh.bsky.social · 17/11/2025
Human brain R2* transitions across birth from the womb to early infancy www.nature.com/articles/s42...
nature.com
Human brain R2* transitions across birth from the womb to early infancy - Communications Biology
Using 147 MRIs (25–60 weeks), this first longitudinal study of R2* across fetal to neonatal periods shows distinct regional trajectories, with linear and non-linear patterns reflecting iron-related ma...
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Jamie Hanson @jamielarsh.bsky.social · 15/11/2025
Age-Related Changes in the Amygdala From In Utero to Early Childhood: Association With Social and Cognitive Outcomes onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com
Age‐Related Changes in the Amygdala From In Utero to Early Childhood: Association With Social and Cognitive Outcomes
This study investigates amygdala maturation from the fetal period through early childhood using MRI across six cohorts. Findings revealed sex and hemispheric differences in growth trajectories, with ....
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Reposted by Jamie Hanson
Jamie Hanson @jamielarsh.bsky.social · 12/11/2025
How Family Assets and Debts Relate to Children's Achievement and Behavior Problems Across Development onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com
How Family Assets and Debts Relate to Children's Achievement and Behavior Problems Across Development
Wealth matters for children's academic achievement and behavioral functioning; however, little is known about how the components of wealth, particularly assets and debts, uniquely relate to children'...
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Jamie Hanson @jamielarsh.bsky.social · 12/11/2025
How Family Assets and Debts Relate to Children's Achievement and Behavior Problems Across Development onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com
How Family Assets and Debts Relate to Children's Achievement and Behavior Problems Across Development
Wealth matters for children's academic achievement and behavioral functioning; however, little is known about how the components of wealth, particularly assets and debts, uniquely relate to children'...
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Jamie Hanson @jamielarsh.bsky.social · 03/11/2025
Metabolism and the mind: Investigating the link between glucose control and reinforcement learning in humans www.sciencedirect.com/science/arti...
sciencedirect.com
Metabolism and the mind: Investigating the link between glucose control and reinforcement learning in humans
Signals from the body profoundly influence cognition. This process is known as interoception, and has been extensively studied in the cardiac, respira…
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Jamie Hanson @jamielarsh.bsky.social · 03/11/2025
From big to small: Emerging methods for enhancing precision psychiatry through transfer learning www.sciencedirect.com/science/arti...
sciencedirect.com
From big to small: Emerging methods for enhancing precision psychiatry through transfer learning
Identifying reliable links between individual differences in neurobiological features and differences in symptom profiles or treatment outcomes is a p…
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