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faurelab.bsky.social

@faurelab.bsky.social
678 followers 201 following 43 posts

Neuroscience lab. We study decision making, exploration and addiction. We are interested in inter-individual variability.

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Reposted by @faurelab.bsky.social
Nicolas Guyon @nicolasguyon.bsky.social · 24/07/2026
New work from our lab @faurelab.bsky.social expending the tools available to study nicotinic receptors more precisely. @espciparispsl.bsky.social @psl-univ.bsky.social
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fjmeye.bsky.social @fjmeye.bsky.social · 04/04/2026
Our new study on neurobiology of stress-driven food intake. www.nature.com/articles/s41... In mice, PFC controls lateral hypothalamus through a multi-branched network. Stress causes differential plasticity across branches, priming the network to promote bingeing. #stresseating
nature.com
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faurelab.bsky.social @faurelab.bsky.social · 02/04/2026
New paper in Nature, @nature.com (go.nature.com/4c4OjCj) : how do social roles emerge in groups of near-identical individuals ? we find that they are neither predetermined nor fixed.
go.nature.com
Dopaminergic mechanisms of dynamical social specialization - Nature
Longitudinal tracking of mice reveals that stable, specialized social roles emerge spontaneously within groups during a foraging task, with dopaminergic activity in the ventral tegmental area driving ...
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faurelab.bsky.social @faurelab.bsky.social · 27/02/2026
1/4 When rules change, dopamine (DA) changes what it calls an “action”. New bioRxiv version: “Dopamine tracks adaptive learning of action representations”. www.biorxiv.org/content/10.1... This project brought together Maxime Come’s PhD work and Arnaud Lespart’s postdoctoral work in our lab.
biorxiv.org
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faurelab.bsky.social @faurelab.bsky.social · 09/01/2026
Congratulations Lauren
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Antoine Bergel @antbergel.bsky.social · 29/12/2025
⚠️ New paper alert and what a way to end 2025! 🎉 Happy to share our story “Sleep-dependent infraslow rhythms are evolutionarily conserved across reptiles and mammals.” published today in Nature Neuroscience. Sleeping dragons 🦎 and functional ultrasound! Read the full paper here: rdcu.be/eWJHb 1/8
rdcu.be
Sleep-dependent infraslow rhythms are evolutionarily conserved across reptiles and mammals
Nature Neuroscience - Bergel et al. show that an infraslow rhythm connecting the brain and body during sleep is shared by lizards, mammals and birds, revealing an ancestral process and reshaping...
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faurelab.bsky.social @faurelab.bsky.social · 10/12/2025
Congrats, well deserve
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Reposted by @faurelab.bsky.social
Emmanuel Perisse @manuperisse.bsky.social · 15/09/2025
You just finished your PhD and you are looking for a postdoc to study stress-dependent modulation of learning. We are using the powerful fly model to understand the underlying circuits and mechanisms. You can apply here: emploi.cnrs.fr/Offres/CDD/U...
emploi.cnrs.fr
Portail Emploi CNRS - Offre d'emploi - Postdoc position (M/F) in Neuroscience, stress modulation of learning (H/F)
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faurelab.bsky.social @faurelab.bsky.social · 17/09/2025
Big news for @laurenmac.bsky.social ! 2025 is quite a year: CNRS position + ERC Starting Grant Her project DeMARRe will study how adolescent exploration & risk-taking shape neural circuits and resilience in adulthood. @cnrs.fr @espciparispsl.bsky.social www.insb.cnrs.fr/fr/personne/...
insb.cnrs.fr
Lauren Reynolds
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katja heuer @k4tj4.bsky.social · 27/07/2025
1 To predict the behaviour of a primate, would you rather base your guess on a closely related species or one with a similar brain shape? We looked at brains & behaviours of 70 species, you’ll be surprised! 🧵Thread on our new preprint with @r3rt0.bsky.social , doi.org/10.1101/2025...
Brain Surfaces of 70 primate species
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CNRS Biologie @cnrsbiologie.bsky.social · 10/07/2025
Alcool et nicotine : un même circuit cérébral à l’origine de la récompense et de l’anxiété 👋 @cnrs-paris.bsky.social @espciparispsl.bsky.social ✍️ @faurelab.bsky.social & Fabio Marti 👉 Lire l'article dans buff.ly/vE1j6LP buff.ly/fD5DOxu
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faurelab.bsky.social @faurelab.bsky.social · 05/07/2025
Nicotine doesn’t just “turn on” the brain’s reward circuits — it reshapes them. Our new paper in Nature Communications shows that activating reward-linked dopamine neurons also sets off a feedback loop that drives negative emotional states. www.nature.com/articles/s41...
nature.com
Nicotine engages a VTA-NAc feedback loop to inhibit amygdala-projecting dopamine neurons and induce anxiety-like behaviors - Nature Communications
Drugs of abuse exert both motivational and emotional effects. Here, the authors show that nicotine and ethanol activate a VTA–NAc loop that inhibits dopamine neurons projecting to the amygdala, thereb...
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faurelab.bsky.social @faurelab.bsky.social · 19/06/2025
Our work on the role of the interpeduncular nucleus in nicotine reward ( www.cell.com/neuron/abstr... ) is featured in a Neuron Preview ! Brandon J Henderson highlights how a new regulatory circuit controlling nicotine reinforcement has been uncovered. www.cell.com/neuron/abstr...
cell.com
Slowing the drive: A new regulatory break for nicotine reward-related behaviors
In this issue of Neuron, Jehl et al. developed a “suicide” antagonist to demonstrate that the interpeduncular nucleus acts as a regulatory controller of nicotine reward-related behavior through connec...
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faurelab.bsky.social @faurelab.bsky.social · 13/06/2025
Yesss! So happy to see this, totally deserved!
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Luc Estebanez @lucestebanez.bsky.social · 05/06/2025
Our work on rubber hand embodiment in mice is out @plosbiology.org! We show that just like in humans, visuo-tactile pairing can lead mice to an embodiment-like behavior with respect to an artificial limb.
journals.plos.org
Embodiment of an artificial limb in mice
Body ownership disorders can be triggered by disease or body damage in humans. This study shows, using an automated, videography-based procedure, that mice also display quantifiable behavioral markers...
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Reposted by @faurelab.bsky.social
Jérémie Naudé @jeremie-n.cpesr.fr · 28/05/2025
Nouvel article avec mes ami-es belges E. Chaves et A. de Kerchove où on décrit l'effet de l'activation de populations de neurones du striatum sur les stratégies de décision. On a essayé de sortir d'une définition "par l'expérimentateur" de la performance des souris. www.science.org/doi/10.1126/...
science.org
Direct and indirect striatal projecting neurons exert strategy-dependent effects on decision-making
In the dorsomedial striatum, d-SPNs increase risk seeking, while iSPNs amplify the value of large gains in decision making.
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Reposted by @faurelab.bsky.social
Bassem Hassan @bassemh.bsky.social · 07/05/2025
Hot off the press: The excellent Maheva Andriatsilavo and colleagues show how a temporal sequence of stochastic molecular mechanisms allow the emergence of stereotyped individualised neuronal circuits. Just published in Nature Neuroscience: rdcu.be/ek010
rdcu.be
Sequential and independent probabilistic events regulate differential axon targeting during development in Drosophila melanogaster
Nature Neuroscience - The developmental origin of behavioral individuality is unclear. The authors show that a temporal sequence of genetically encoded stochastic mechanisms explains variation in...
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Louis-Eric Trudeau @louistrudeau.bsky.social · 24/04/2025
I have an opening in my lab for a postdoctoral fellow to work on projects that relate to the mechanisms of neurotransmitter release by dopamine neurons and/or on how inflammatory signals infuence the functionning of these neurons. Please share.
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faurelab.bsky.social @faurelab.bsky.social · 21/04/2025
The interpeduncular nucleus (IPN) dampens nicotine reward via β4* nAChRs and IPN→LDTg projections. Blocking this pathway enhances VTA responses and CPP: A nicotine-specific brake embedded in the mesolimbic system. New paper from the lab out in @cp-neuron.bsky.social www.cell.com/neuron/abstr...
cell.com
The interpeduncular nucleus blunts the rewarding effect of nicotine
Nicotine activates the dopamine reward system to promote consumption and addiction, but the brain has a natural brake to counteract it. Jehl, Ciscato, Vicq, Guyon, et al. identified the interpeduncula...
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Reposted by @faurelab.bsky.social
Nils Kolling @nilskolling.bsky.social · 08/04/2025
Registrations for the Symposium for the Biology of decision making (SBDM) in Lyon 2025 are finally open! sbdm2025.github.io Please spread the message!
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faurelab.bsky.social @faurelab.bsky.social · 11/02/2025
New preprint from the lab and @clementsolie.bsky.social on social organization & neuromodulation! Read the full preprint here: www.biorxiv.org/content/10.1... @espciparispsl.bsky.social @cnrsbiologie.bsky.social
biorxiv.org
Dopaminergic mechanisms of dynamical social specialization in mouse microsocieties
Social organization and division of labor are fundamental to animal societies, but how do these structures emerge from individual interactions, and what role does neuromodulation play in shaping them?...
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Anastasia Christakou 💙 @christakou.bsky.social · 22/01/2025
This is one of my favourite papers for a while. Theoretically informed, technically accomplished, well-written and argued, articulates explanation 👏 By @jeremie-n.bsky.social and colleagues. I would love to teach it but it may be a lot... www.nature.com/articles/s41...
nature.com
Dopamine builds and reveals reward-associated latent behavioral attractors - Nature Communications
The reason why manipulating dopamine (DA) activity can affect both action latency, action direction, and movement vigor, but only in certain animal states and behavioral settings is not fully understo...
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faurelab.bsky.social @faurelab.bsky.social · 05/02/2025
Superb study from Thomas Preat's team here @espciparispsl.bsky.social @cnrsbiologie.bsky.social , showing that astrocytes use redox H₂O₂ signaling to support memory in Drosophila. Amyloid-β disrupts this process, linking it to cognitive deficits in Alzheimer’s. www.nature.com/articles/s42...
nature.com
Astrocyte-to-neuron H2O2 signalling supports long-term memory formation in Drosophila and is impaired in an Alzheimer’s disease model - Nature Metabolism
Rabah et al. discover an astrocyte-to-neuron hydrogen peroxide signalling cascade, which is crucial for long-term memory formation in Drosophila. This signalling is found to be inhibited by amyloid-β ...
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CNRS Biologie @cnrsbiologie.bsky.social · 22/01/2025
#RésultatScientifique🔎Comment la dopamine peut-elle orchestrer à la fois l’apprentissage et la motivation ? @jeremie-n.bsky.social propose une réponse à cette question dans @naturecomms.bsky.social ⤵️ 🤝 @cnrsoccitanieest.bsky.social @umontpellier.bsky.social @cnrsinformatics.bsky.social
buff.ly
De l’apprentissage à l’action : la dopamine révèle nos apprentissages cachés
La dopamine, une molécule clé dans le cerveau, est essentielle à l’
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Philippe Domenech @philippedomenech.bsky.social · 14/11/2024
🚨 !!! Postdoc Position Available !!! 🚨 Join our team at the Neuromodulation Institute (Hôpital St-Anne) in Paris, France. Work on cutting-edge research involving voltammetric recordings in human patients and machine learning. 🧠🟦 / 🧠🤖 / 🧠🩺 #AcademicSky #postdoc
A view of Saint-Anne hospital in Paris
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faurelab.bsky.social @faurelab.bsky.social · 14/11/2024
"Dopamine builds and reveals reward-associated latent behavioral attractors". This study combines computational modeling and experimental work to reveal how DA not only teaches, but also motivates, i.e by creating and using pathways toward goals. www.nature.com/articles/s41...
nature.com
Dopamine builds and reveals reward-associated latent behavioral attractors - Nature Communications
The reason why manipulating dopamine (DA) activity can affect both action latency, action direction, and movement vigor, but only in certain animal states and behavioral settings is not fully understo...
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Lauren Reynolds @laurenmac.bsky.social · 11/11/2024
Paper from my PD with @faurelab.bsky.social came out a couple weeks ago #neuroskyence #neuroscience www.nature.com/articles/s41...
nature.com
Transient nicotine exposure in early adolescent male mice freezes their dopamine circuits in an immature state - Nature Communications
How nicotine impacts the adolescent development of neural circuitry is not fully understood. Here authors show that early adolescent nicotine exposure in male mice blocked the maturation of nicotine-e...
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faurelab.bsky.social @faurelab.bsky.social · 08/11/2023
Adolescence is a critical period for nicotine addiction. We found that early nicotine exposure "freezes” dopamine circuits in an immature state, leading to lifelong vulnerability. Details can be checked in new Lab preprint www.biorxiv.org/content/10.1... - Congrats @laurenmac.bsky.social
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