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Adult intestinal size plasticity is driven not only by epithelial stem cells but also by remodeling of the surrounding visceral musculature. Sex- and reproduction-dependent muscle remodeling controls ...

Inside cells, DNA is intimately associated with proteins, forming chromatin. The protein constituents of chromatin vary across the tree of life: histones are the principal building blocks of chromatin...

In Drosophila, cell fate switching in adult intestinal stem cells is determined through an epigenetic mechanism in which these cells count divisions, switching from producing enterocytes to producing ...

The Medical Research Council Mitochondrial Biology Unit (MRC MBU), University of Cambridge, wishes to appoint two post-doctoral Research Associates to join the research group of Prof. Mike Murphy at t...

Robust and controlled intestinal regeneration involves reciprocal interactions between the intestinal epithelium and its microenvironment. Here, we id…

Abstract. The ever-increasing amounts of plastic waste and greenhouse gas emissions worldwide threaten our environment. Biomedical laboratories across the

Sign up is close for now, but please add your name here for the next matching cycle. Thanks for volunteering to be a Mentor! The 2025 C. elegans Community Mentor Match is open to postdocs and faculty...

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Stem cells perceive and respond to biochemical and physical signals to maintain homeostasis. Yet, it remains unclear how stem cells sense mechanical signals from their niche in vivo. In this work, we ...

Pioneering women in ageing research. Photo credits: Marjory Warren, Photo: Archives of the British Geriatrics Society; Lillien Martin, courtesy of the Department of Special Collections, Stan...

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Endogenous mitochondrial NAD(P)H fluorescence enables label-free and subcellular resolution quantification of aging, prediction of remaining lifespan and tracking of age-dependent changes to mitochond...

Enhancers play an essential role in developmental processes by orchestrating the spatial and temporal regulation of gene expression. However, mapping the location of these regulatory elements in the g...

Aging Biology Update (ABU) is a monthly compilation of aging research as it appears in the scientific literature and lay press. ABU, a publication of the UAB N

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