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Lisa Buchauer

@libuchauer.bsky.social
792 followers 926 following 45 posts

Computational Biologist. Mathematical models, omics methods and data analysis for immunology and infection research at Charité Berlin. buchauer-lab.eu

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Reposted by Lisa Buchauer
Lisa Buchauer @libuchauer.bsky.social · 07/01/2026
I'm excited to announce we're recruiting a PhD student in Machine Learning for Immunology within the Einstein Center for Early Disease Interception, together with Simon Haas!
lnkd.in
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Lisa Buchauer @libuchauer.bsky.social · 07/01/2026
I'm excited to announce we're recruiting a PhD student in Machine Learning for Immunology within the Einstein Center for Early Disease Interception, together with Simon Haas!
lnkd.in
LinkedIn
This link will take you to a page that’s not on LinkedIn
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Reposted by Lisa Buchauer
MRC Weatherall Institute of Molecular Medicine @imm.ox.ac.uk · 18/11/2025
#ScientistSpotlight: This week we’re introducing Verena Körber, one of the newest Group Leaders at the MRC WIMM. @rdm.ox.ac.uk @medsci.ox.ac.uk @ox.ac.uk
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Adlung Lab @adlunglab.com · 16/11/2025
We care a lot about time. Now one of my best science friends, Melania Barile, et al. introduce TemporalVAE, a deep generative model that maps scRNA-seq data onto developmental time! It works with zero-shot & identifies time-sensitive genes @natcellbio.nature.com 🧪
doi.org
TemporalVAE: atlas-assisted temporal mapping of time-series single-cell transcriptomes during embryogenesis
Nature Cell Biology - Liu et al. present TemporalVAE, a method for integrating single-cell time course data. The model proposes a workflow to determine the biological timing of samples and its...
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Reposted by Lisa Buchauer
Die Junge Akademie @jungeakademie.bsky.social · 07/10/2025
Im November macht das #Utopiemobil erneut Halt im #Futurium in #Berlin. Am 13.11. geht es im Rahmen eines 🌟Open Lab Abends🌟ab 17 Uhr um die Zukunft der #Wissenschaftskommunikation. U.a. mit @leoniewenz.bsky.social und @libuchauer.bsky.social Alle Infos:🔗 www.diejungeakademie.de/de/veranstal...
Foto: Die Junge Akademie/Bernd Brundert
Vier Fotos eines modularen Außenpavillons. Oben links: Innenraum aus beigem Holz mit zwei runden Fenstern, einem rosa Sitzkissen, freiliegenden Drähten und metallischen Luftschlangen. Oben rechts: eine durchsichtige Kuppel auf einem rosafarbenen runden Sockel. Unten links: silberne und rosafarbene geschwungene Außenansicht auf Kies unter Bäumen, ein Ende offen mit einem kurzen Vorhang. Unten rechts: Innenansicht mit einem runden Fenster, einer rosa Tafel mit Text und Luftschlangen.
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Die Junge Akademie @jungeakademie.bsky.social · 09/09/2025
🔍 Wir suchen als Verstärkung eine Leitung für unsere Geschäftsstelle in #Berlin! 📍💼 ✍️ Hier bewerben: karriere.leopoldina.org/jobposting/e... #Job #Stellenausschreibung #Stellenangebot #Organisationsentwicklung #Personalführung #Wissenschaftskommunikation #Wissenschaftsmanagement
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Dominic Grün @dominicgrun.bsky.social · 02/07/2025
Few dates left to apply for this tenure-track professorship on Single-Cell Systems Biology in my department at @uni-wuerzburg.de. Competitive package and highly attractive research environment at the Institute of Systems Immunology.
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Reposted by Lisa Buchauer
Saez-Rodriguez Group @saezlab.bsky.social · 02/07/2025
Postdoc position in our group at @ebi.embl.org about analyzing single cell data sets to better understand and treat neurodegen diseases, in collab with A Bassett, M Lotfollahi, @bayraktarlab.bsky.social, M Strauss and others within Open Targets. Deadline 20/07. Please share tinyurl.com/87wj466m
tinyurl.com
Postdoctoral Fellow in computational modelling of NeuroImmune Mechanisms of Neurodegeneration (Open Targets)
Your role As a Postdoctoral Fellow on the NeuroImmune Open Targets project, you will develop and apply integrative computational pipelines to dissect immune-cell phenotypes and cell–cell interactions ...
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Saez-Rodriguez Group @saezlab.bsky.social · 02/07/2025
We have a curator position at @ebi.embl.org to work with GSK within a project to understand fibrotic processes (no PhD required). Deadline 20th July. Please share 🙏 embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
embl.wd103.myworkdayjobs.com
Scientific Database Curator – Fibrosis Transcriptomics
We are seeking a technically skilled and biologically literate Scientific Database Curator to join a focused initiative on fibrosis research, hosted at EMBL-EBI in collaboration with the Saez-Rodrigue...
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Lisa Buchauer @libuchauer.bsky.social · 02/07/2025
We are currently recruiting a bioinformatics/computational biology postdoc to join the infrastructure project of a newly funded large research consortium (SFB-TRR) on Circadian Medicine between Charité - Universitätsmedizin Berlin and Universität zu Lübeck ⌚ ⏰ ⏱️ 🕰️ !
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Leif Erik Sander 🇪🇺🇺🇦 @sanderlab.bsky.social · 25/06/2025
US terminates its support for @gavi.org the vaccine alliance that supplies life-saving vaccines the world’s poorest. Vaccines are among the safest, most effective prevention measures ever introduced. This is a disastrous and short-sighted decision!
reuters.com
US to stop financial support of global vaccine alliance Gavi, health secretary says
Health Secretary Robert F. Kennedy Jr said on Wednesday that the U.S. government will no longer contribute to Gavi, accusing the group that helps buy vaccines for the world's poorest children of ignoring safety, without providing evidence.
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Lisa Buchauer @libuchauer.bsky.social · 12/06/2025
decoupler has been very useful for us & helps you dive into meaningful sc analysis quickly! small suggestion to increase uptake: consider changing the logo, at least two python users here initially immediately closed the tab as they thought is was an R package🙃
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Max Delbrück Center @mdc-berlin.bsky.social · 12/06/2025
💡 Great science needs great environments. We are proud that our Single Cell Focus Area is among the ten “Best Research Environments 2024” – selected by @jungeakademie.bsky.social‬ together with the @volkswagenstiftung.de. Congratulations! 🥳 More details: 👉 www.diejungeakademie.de/en/press/bes... 👈
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Christian Gaebler @cgaebler.bsky.social · 05/06/2025
Honored that our lab made the shortlist for Best Research Environment. Awesome initiative by Junge Akademie and proud of the incredible Gaebler Lab team and the entire Infectious Disease Department at Charité/BIH that makes this place what it is! 👏 @libuchauer.bsky.social @sanderlab.bsky.social
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Lisa Buchauer @libuchauer.bsky.social · 05/06/2025
@cgaebler.bsky.social well done :))
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Die Junge Akademie @jungeakademie.bsky.social · 04/06/2025
🧬Unter den Top 24 der besten Forschungsumfelder ist auch die Single #Cell Focus Area. Sie vereint die Forschung der Charité Berlin, des @bihatcharite.bsky.social, des @mdc-bimsb.bsky.social und des @mdc-berlin.bsky.social. Der Preis wird im Juni ausgelost. 👉 www.diejungeakademie.de/de/projekte/...
Das Gruppenfoto zeigt 45 Personen auf einer Holzterrasse vor einer Straße, Palmen und dem Meer.
Bildrechte bei Ashley Sanders, MDC
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Lisa Buchauer @libuchauer.bsky.social · 17/05/2025
Welcome Roberta, excited to have you with us & wishing you good luck!
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Adlung Lab @adlunglab.com · 07/04/2025
🚨 Preprint Alert! New work from the group! 🟤 We set out to explore how brown adipose tissue (BAT) adapts to cold. 🧬🖥️ Using single-nucleus mRNA-sequencing, we dissected murine BAT and uncovered distinct adipocyte subtypes. 🫓 One in particular stood out... 🧵 1/7
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Lisa Buchauer @libuchauer.bsky.social · 27/03/2025
Guten Morgen Dresden! #tagungmitbabyundschwiegermutterwhatcouldgowrong
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Sawitzki Lab @sawitzkilab.bsky.social · 18/03/2025
📣 Job alert! 📣 We are are looking for a talented bioinformatician to join us at the Berlin Institute of Health at Charité to analyze multiomics data in post-COVID-19 and ME/CSF syndrome research. Please share and come join us! ⬇️ #ImmunoSky #Bioinformatics #Immunology #ComputationalBiology #MedSky
bihealth.org
Computational Scientist (d/f/m) in Translational Immunology
Vollzeit | 16.04.2025 | BIH Berlin Mitte
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Nils Blüthgen @molsysbio.bsky.social · 11/03/2025
Come and join our seminar series!
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Nils Blüthgen @molsysbio.bsky.social · 02/03/2025
I had similar issues about a week ago, I guess the server now unstable with all the staff fired and chaos caused by ElMu and Trump - try the European one: europepmc.org, often anyway more useful as it includes biorxiv.
europepmc.org
Europe PMCHome - Europe PMC
Europe PMC is an archive of life sciences journal literature.
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Nils Blüthgen @molsysbio.bsky.social · 24/02/2025
See you in Dublin in October for the ICSB2024! Early registration is open at: ICSB2025.com. I will chair an exciting session on "Cell Engineering & Pathway Engineering".
Registration is now open, visit ICSB2025.com
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Christian Gaebler @cgaebler.bsky.social · 24/02/2025
Thank you to Stiftung Charité for featuring me and my group in the FACES interview series! www.stiftung-charite.de/en/news-in-d...
stiftung-charite.de
In conversation with Christian Gaebler, the physician-scientist promoting HIV research in Berlin
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Berlin-Brandenburgische Akademie der Wissenschaften @bbaw.bsky.social · 04/12/2024
Was bringt der Wandel? Wie gehen wir in Wissenschaft und Gesellschaft damit um? Wie verändern sich Wissenschaft und Gesellschaft selbst? Reisen Sie beim #SalonSC durch #Metamorphosen in Geschichte und Gegenwart - am 18.1.25 ab 18 Uhr in der BBAW. salon.bbaw.de/start
Metamorphosen: Salon Sophie Charlotte
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Lisa Buchauer @libuchauer.bsky.social · 18/01/2025
Freue mich drauf, heute Abend als neues Mitglied der Jungen Akademie beim Salon Sophie Charlotte salon.bbaw.de/start der BBAW dabei zu sein! Kommt vorbei und lernt unsere Forschung durch ein besonderes Quartett-Spiel kennen 🃏🃏🃏🃏. Raum 230, 19/20/21 Uhr!
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Kresten Lindorff-Larsen @lindorfflarsen.bsky.social · 15/01/2025
This! Also well put in this editorial in PLOS Comp Biol: Putting benchmarks in their rightful place: The heart of computational biology doi.org/10.1371/jour...
Screenshot from paper that says:
"Developing good and comprehensive benchmarks, in which the performance metrics of each tool reflect its real-world utility, requires a significant effort. For highly competitive and established fields, such as protein structure predictions, community experiments evaluating the methods have been held periodically to provide blinded assessments of prediction performance. These blinded assessments are perhaps the gold standard on how benchmarks should be run. However, in most areas of computational biology, no such regular blinded contests are available. Instead, many tool developers end up generating their own benchmarks, which they publish alongside a newly developed tool to show its improved performance. The downside of this approach is that, if a new approach is developed in parallel to assembly of the benchmark on which it is evaluated, there is a strong selection bias encouraging the authors to report tool development approaches performing well against the benchmark compared to previous tools. This reporting bias makes most benchmarks that accompany newly developed tools questionable. Even if the authors are aware of this problem and take conscious steps to separate benchmark, evaluation method, and method development, subconscious bias may persist and affect the final outcome."
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Altuna Akalin @al2na.bsky.social · 07/01/2025
Learn how to analyze spatial omics data! Join our computational genomics course in 2025. Application deadline 30th January. compgen.mdc-berlin.de 🖥️ 🧬 🧪
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Adlung Lab @adlunglab.com · 07/01/2025
🔗 Dive into this fascinating work here: doi.org/10.1038/s414... . 🏁 Kudos to Anna Huhn et al. for this remarkable contribution to basic immunology! 🧪 5/5
doi.org
The molecular reach of antibodies crucially underpins their viral neutralisation capacity
Nature Communications - Researchers developed an accurate model to analyse bivalent antibody binding. By analysing many SARS-CoV-2-specific antibodies, they found that their molecular reach can...
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Wolfgang Huber @wkhuber.bsky.social · 03/01/2025
How to do differential expression with scRNAseq data? State of the art is "pseudo-bulk" analysis with RNA-seq methods like edgeR or DESeq2, where "cell type" is encoded as discrete categories. Biologically, discrete categories are not always the most appropriate concept.(1/3) doi.org/10.1038/s415...
doi.org
Analysis of multi-condition single-cell data with latent embedding multivariate regression - Nature Genetics
Latent embedding multivariate regression models multi-condition single-cell RNA-seq using a continuous latent space, enabling data integration, per-cell gene expression prediction and clustering-free ...
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Constantin Ahlmann-Eltze @const-ae.bsky.social · 03/01/2025
LEMUR is directly useable for your next single-cell differential expression project! R package: github.com/const-ae/lemur Python package: pylemur.readthedocs.io/en/latest/ Code from the paper: github.com/const-ae/lem...
R and Python code to call LEMUR
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Leif Erik Sander 🇪🇺🇺🇦 @sanderlab.bsky.social · 02/01/2025
Petition der Gewerkschaft der Polizei #GdP für ein bundesweites „Böllerverbot“
innn.it
Bundesweites Böllerverbot, jetzt!
Jetzt Petition auf innn.it unterschreiben und Gewerkschaft der Polizei Berlin unterstützen!
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Francesca Finotello 🖥️🧬 @francescafinotello.bsky.social · 12/11/2024
🧬 🖥️ Need help for investigating tissue complexity from #spatial #transcriptomics data? Try out our #spacedeconv R package! 💻 Code: github.com/omnideconv/s... 📝 Preprint: www.researchsquare.com/article/rs-5...
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Emanuel Wyler @ewyler.bsky.social · 13/12/2024
Nach den neusten RKI-Zahlen sinken die Impfquoten gegen verschiedene ansteckende Krankheiten wie Polio (Kinderlähmung). Gerade in Kreisen mit ohnehin niedrigeren Polio-Impfquoten (Beispiele Main-Tauber und Deggendorf in der Grafik) ging es drastisch nach unten; deutlich weniger Veränderungen wo…
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Leif Erik Sander 🇪🇺🇺🇦 @sanderlab.bsky.social · 14/12/2024
Impfquoten für Grippe & Pneumokokken sind miserabel in Deutschland. Beides sind günstige, gut verträgliche, sichere Impfstoffe & stellen eine der wirksamsten & einfachsten Präventionsmaßnahmen gegen schwerwiegende Erkrankungen wie Lungenentzündung, ARDS & Sepsis dar! www.rki.de/DE/Content/I...
Impfquoten über die Zeit von 2008-2023 bei Erwachsenen mit Indikation zur Impfung  gegen Influenza und Pneumokokken. Impfquoten für Influenza zwischen 30-50% und Pneumokokken 10-20%
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Dominic Grün @dominicgrun.bsky.social · 11/12/2024
A few days left to apply if you would like to work on spatial multi-omics modeling in an interdisciplinary team!
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Leif Erik Sander 🇪🇺🇺🇦 @sanderlab.bsky.social · 04/12/2024
HIV - Heilung in Sicht? Sehr informativer und differenzierter Artikel in der @taz.de über die Fortschritte und Herausforderungen in der HIV-Forschung & Therapie und der Lange Weg zur Heilung. @cgaebler.bsky.social gibt spannende Einblicke in seine Forschung an der Klinik f. Infektiologie #Charité
taz.de
HIV-Forschung: Kurz vor der Heilung?
Einst bedeutete Aids den Tod, heute ist es eine gut behandelbare Erkrankung. Aber heilen lässt sie sich noch nicht. In Berlin will man das ändern.
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Tomàs Montserrat Ayuso @tmontsay.bsky.social · 03/12/2024
Not checking nuclear markers like MALAT1 or intronic reads in your scRNA-seq data?🚨 We show their power to flag low-quality cells—even in top public datasets. It’s time to prioritize better QC for cleaner, more reliable genomics research! Read more: bmcgenomics.biomedcentral.com/articles/10.... 1/8
bmcgenomics.biomedcentral.com
High content of nuclei-free low-quality cells in reference single-cell atlases: a call for more stringent quality control using nuclear fraction - BMC Genomics
The advent of droplet-based single-cell RNA-sequencing (scRNA-seq) has dramatically increased data throughput, enabling the release of a diverse array of tissue cell atlases to the public. However, we...
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Dominic Grün @dominicgrun.bsky.social · 20/11/2024
Hiring! I'm looking for a postdoc in machine learning of spatial single-cell data. Exciting project to develop methods for modelling cellular circuits in disease and regeneration of heart, liver and bone marrow using Xenium data from our lab. tinyurl.com/ymkvk7vn
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Christian Gaebler @cgaebler.bsky.social · 27/11/2024
Join us for a World Aids day Fundraiser special event at Moviemento Berlin featuring short films curated by Xposed, and short introductions into our research work as well as valuable insights from representatives of TransSe*works and Deutsche Aidshilfe moviemento.de/film/world-a...
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Dr. Amy Lee @minisciencegirl.bsky.social · 21/11/2024
Every year, >200K newborns die from sepsis. Our team used machine learning to develop a set of genes that can predict neonatal sepsis risk using at birth blood samples. www.thelancet.com/journals/ebi...
thelancet.com
Predictive gene expression signature diagnoses neonatal sepsis before clinical presentation
Despite appearing healthy at birth, neonates who later developed EOS already had distinct whole blood gene expression changes at birth, which enabled the development of a 4-gene predictive signature f...
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Christian Gaebler @cgaebler.bsky.social · 18/11/2024
🚨 One week left to apply! 🚨 Don’t miss the chance to join the Gaebler & Ibrahim Labs for a cutting-edge postdoc position at the intersection of viral immunology, virology & gene regulation. 👉Apply here charite.hrpuls.de/de/job-offer...
charite.hrpuls.de
Postdoctoral Scientist (d/f/m) in Life Sciences/Genetics
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Lisa Buchauer @libuchauer.bsky.social · 13/11/2024
ConvexGating allows to turn labeled groups/clusters (e.g. those derived with graph based algorithms) of highdim cytometry data into interpretable gating strategies with potential for marker discovery cell sorting -- congrats Maren & team and we will give it a try!
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Danna Staaf @dannastaaf.bsky.social · 13/11/2024
😍 They are so beautiful, how could I not?? I did a whole "mother's milk" series in 2023, when my book Nursery Earth came out, to showcase little-known lactators
A poster titled "Mother's Milk" with a three-by-three grid of color-pencil illustrations of little-known lactators: whale, wombat, echidna, flamingo, caecilian, shark, spider, fly, and cockroach. Each drawing has a fact written below about how that animal produces milk to feed its young.
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Lisa Buchauer @libuchauer.bsky.social · 13/11/2024
well if this isn't what we're here for 🤩
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Alasdair Munro @apsmunro.bsky.social · 12/11/2024
MYCOPLASMA PNEUMONIAE This cheeky little intracellular bacteria seems to be up to mischief with kids in the USA at the moment A quick thread on this bug, what's going on, and what to do (or not do!) about it #IDSky #PedSky #PedsIDSky 🧪 1/🧵
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Francesca Finotello 🖥️🧬 @francescafinotello.bsky.social · 12/11/2024
🧬 🖥️ If you are looking for more tools, resources, and insights about next-generation #deconvolution, have a look at our #omnideconv website: omnideconv.org
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Janine George @molecularxtal.bsky.social · 09/11/2024
35 years after the Berlin wall came down. Signs drawn by people from Berlin were put up along 5 kms of where the former wall was standing. Extremely impressive and it somehow gives a tiny bit of hope how many people wrote about democracy.
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Hope Tanudisastro @htanudisastro.bsky.social · 04/11/2024
📢 New preprint alert: Excited to share our deep dive into the role of tandem repeats (TRs) in single-cell gene expression across the immune system, using WGS and scRNA-seq data from 1,790 individuals and over 5 million blood cells! 🧬 🧵👇 #repeats #SingleCell 1/9
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Reto Fiolka @retof.bsky.social · 08/11/2024
Intricate shape of a dendritic cell, guardians of the immune system.
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