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Sawitzki Lab

@sawitzkilab.bsky.social
513 followers 284 following 29 posts

Translational Immunology Group at Charité - Universitätsmedizin Berlin and Berlin Institute of Health | sawitzki-lab.com

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Sawitzki Lab @sawitzkilab.bsky.social · 30/09/2026
This week we are at #ESSB2026 in Sitges, Barcelona! Adrian is sharing his work on spatial glycoimmunology in gastric cancer. 🔬 #SpatialBiology
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ME/CFS Research Foundation @mecfsresearch.bsky.social · 15/09/2026
Project 7 of our €2.4M funding round: MARK-ME develops minimal biomarker panels for more objective ME/CFS diagnostics, using machine learning on existing immune data. More: t.ly/-0gm2 #mecfsresearch #mecfs
Cover by the ME/CFS Research Foundation: €2.4M for 7 new research projects, Project 7: MARK-ME. Funding period September 2026 to August 2028. Logo of the Berlin Institute of Health at Charité, address projects.mecfs-research.org.Text graphic by the ME/CFS Research Foundation: Diagnosing ME/CFS relies on clinical criteria, and objective biomarkers are not yet available. They could complement diagnosis, reduce uncertainty and delays, and serve as measures in clinical trials.Text graphic by the ME/CFS Research Foundation: Biomarkers are gaining importance because research points to biological heterogeneity in ME/CFS. In a subgroup of patients, immune dysregulation and autoimmune mechanisms play a central role.Text graphic by the ME/CFS Research Foundation: MARK-ME develops minimal biomarker panels for diagnosis and stratification. Machine learning identifies the most informative combinations from existing immune data. Below, a portrait of Prof. Dr. Birgit Sawitzki.
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Nature Reviews Immunology @natrevimmunol.nature.com · 15/07/2026
Journal club article by @tomikostevc.bsky.social & @sawitzkilab.bsky.social discussing a recent #preprint from @sciencekyle.bsky.social that uses a synthetic cytokine receptor to simultaneously induce inflammatory and phagocytic phenotypes in a macrophage rdcu.be/ftTPx
nature.com
Programming macrophage polarization with synthetic cytokine receptors - Nature Reviews Immunology
A preprint by Lunger et al. reports macrophage engineering through constitutively active synthetic cytokine receptors to induce polarization states that are unobtainable with natural cytokine receptor...
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Tomislav Kostevc @tomikostevc.bsky.social · 14/07/2026
Excited to share a highlight that Birgit Sawitzki and I wrote about a recent preprint on fine-tuning macrophage polarization using synthetic cytokine receptors from the @sciencekyle.bsky.social Lab! @preprintclub.bsky.social
nature.com
Programming macrophage polarization with synthetic cytokine receptors - Nature Reviews Immunology
A preprint by Lunger et al. reports macrophage engineering through constitutively active synthetic cytokine receptors to induce polarization states that are unobtainable with natural cytokine receptor...
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Sawitzki Lab @sawitzkilab.bsky.social · 06/07/2026
Happy to pitch our findings and ideas at the Bioengineering Symposium by @mdc-berlin.bsky.social today
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Deutsche Gesellschaft für Immunologie e.V. (DGfI) @dgfi-org.bsky.social · 02/07/2026
From 25 to 27 June 2026, the 15th Translational Immunology School (TIS) of the #DGfI brought together early-career researchers and leading international experts in Potsdam. 😊 dgfi.org/akademie-fue... Chair: B. Grimbacher, Co-Chair: @sawitzkilab.bsky.social @efis-immunology.bsky.social #immunology
Participants sit at tables and listen to a talk.Posterwalk: A participant presents their poster to a group.Posterwalk: A participant presents their poster to a group.Participants sit at tables and listen to a talk.
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Sawitzki Lab @sawitzkilab.bsky.social · 28/06/2026
Inspiring exchange of ideas and experiences with the next generation of translational immunologists at the Translational Immunology School by @dgfi-org.bsky.social 💡
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Sawitzki Lab @sawitzkilab.bsky.social · 13/05/2026
Great meeting the ME/CFS community last week in Berlin and sharing our latest findings!
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Sawitzki Lab @sawitzkilab.bsky.social · 27/04/2026
Inspiring week at Utrecht University for our team! Our PhD Adrian joined fellow TopGut DCs, and our PI Birgit Sawitzki was there too. A great mix of science, collaboration & new ideas - leaving with fresh perspectives, strong connections & motivation ✈️ Thanks to #HorizonEU & #MSCA DN! #TopGut #PhD
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Sawitzki Lab @sawitzkilab.bsky.social · 23/04/2026
The new research institute Si-M (Der Simulierte Mensch/The Simulated Human), a joint Charité-TU Berlin venture, officially opened!   We are excited to be a part of this new space, combinining biology, data science and engineering to model human physiology and accelerate medical translation! 🧬
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Sawitzki Lab @sawitzkilab.bsky.social · 18/03/2026
Excited to share our new study showing that CD4⁺ and CD8⁺ T cells communicate via the AICL–KLRF1 axis to sustain cytokine production in precursor exhausted T cells. This support is disrupted in tumors, potentially promoting CD8⁺ T cell exhaustion. 🔗 link.springer.com/article/10.1...
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Sawitzki Lab @sawitzkilab.bsky.social · 13/02/2026
Two of our lab members, Christina Iwert and Lev Petrov, have recently successfully defended their PhD theses! Congrats and wishing you both loads success in your careers! 🎓 @woodenrobo.bsky.social
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Sawitzki Lab @sawitzkilab.bsky.social · 31/10/2025
Halloween in Sawitzki Lab 🎃🧙🕸️
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Sawitzki Lab @sawitzkilab.bsky.social · 15/10/2025
We are at the #EMBLSpatialBiology: Melting Pot in beautiful Heidelberg this week! Exciting poster session today where also Matthias and Adrian shared their work. #ESSB2025
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Sawitzki Lab @sawitzkilab.bsky.social · 19/08/2025
Excited to share our new study on how age-related changes in STAT signaling impact antiviral responses and hyperinflammation in COVID-19! 🧵 Explainer thread by the first author Lev Petrov linked below ⬇️
cell.com
Rewired type I IFN signaling is linked to age-dependent differences in COVID-19
Petrov et al. identify an age-dependent shift in interferon signaling during SARS-CoV-2 infection, with older individuals favoring a STAT3-driven inflammatory response. This mechanistic insight helps ...
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Sawitzki Lab @sawitzkilab.bsky.social · 10/07/2025
📣 We are looking for a master student to join us at the @bihatcharite.bsky.social to work on an exciting project in the field of #cancer and #spatialbiology! 🔬 #singlecell #multiomics
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Sawitzki Lab @sawitzkilab.bsky.social · 11/04/2025
Adrian and Birgit are in Porto this week for a meeting of the TOP-GUT #MSCA Doctoral Network. Lots of fun sharing recent discoveries, planning collaborations and getting hands-on training on organoid culture. 🙌
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Sawitzki Lab @sawitzkilab.bsky.social · 03/04/2025
Waking up our sleeping beauty! Super excited to have Xenium and PhenoCycler now running in the same room 🤩 #SpatialOmics #SpatialBiology #SpatialProteomics #SpatialTranscriptomics #Immunology
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Sawitzki Lab @sawitzkilab.bsky.social · 18/03/2025
📣 Job alert! 📣 We are are looking for a talented bioinformatician to join us at the Berlin Institute of Health at Charité to analyze multiomics data in post-COVID-19 and ME/CSF syndrome research. Please share and come join us! ⬇️ #ImmunoSky #Bioinformatics #Immunology #ComputationalBiology #MedSky
bihealth.org
Computational Scientist (d/f/m) in Translational Immunology
Vollzeit | 16.04.2025 | BIH Berlin Mitte
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Sawitzki Lab @sawitzkilab.bsky.social · 15/03/2025
We’re excited to be a part of the Swarm Learning Initiative, working to accelerate immune response analyses in infectious diseases! Anika, Lev, and Birgit joined the 1st Swarm Learning Symposium at @dzne.science, where Anika shared innovative concepts for ex vivo functional analyses. 📈
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Sawitzki Lab @sawitzkilab.bsky.social · 14/03/2025
Exciting to see this story out — showing that children with MIS-C have high levels of TGFβ, which weakens T cells and reactivates EBV. Blocking TGFβ reversed this effect, making this a potential treatment option! Proud to have contributed our part!
nature.com
TGFβ links EBV to multisystem inflammatory syndrome in children - Nature
Multisystem inflammatory syndrome following SARS-CoV-2 infection results from increased serum levels of TGFβ, which impairs the reactivation of virus-specific T cells.
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Lucas Arendholz @lucasarendholz.bsky.social · 18/02/2025
Visited two events with a focus that was new to me - on tech- and methodology. Helpful, technical input and discussions that are often lacking in broader events! ⛰️📊 German Mass Cytometry User Forum - Jena, Germany 1️⃣0️⃣❎️ Single Cell & Spatial Discovery Symposium by 10X Genomics - Munich, Germany
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Sawitzki Lab @sawitzkilab.bsky.social · 14/02/2025
Happy Valentine's Day! 🫶 #FluorescentFriday #SpatialProteomics #Microscopy
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Sawitzki Lab @sawitzkilab.bsky.social · 13/02/2025
As part of BIH Diversity Month, Katherine Deane visited the BIH@Charité and stopped by our lab. Katherine is a renowned expert on accessibility and inclusivity, and we had great time discussing ways to make our lab and the broader scientific community more inclusive!
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Sawitzki Lab @sawitzkilab.bsky.social · 12/02/2025
Lucas @lucasarendholz.bsky.social is presenting his project on post-COVID syndrome (long COVID) at the 8th German Mass Cytometry User Forum in Jena, Germany! 🙌
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Sawitzki Lab @sawitzkilab.bsky.social · 23/01/2025
We're thrilled that the CURE-ME project received funding from the German Federal Ministry of Education and Research! Together with experts from Charité and @tumuenchen.bsky.social, we are investigating the role of Epstein-Barr virus (EBV) in triggering autoreactivity and post-infectious #MECFS.
bihealth.org
EBV may trigger autoreactivity and cause ME/CFS – BIH-led CURE-ME research project awarded federal funding - News - BIH at Charité
The consortium project CURE-ME (Characterizing AUtoimmuneREsponses and Defining Targets in ME/CFS) between the Berlin Institute of Health at Charité (BIH), Charité –Universitätsmedizin Berlin and the ...
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Sawitzki Lab @sawitzkilab.bsky.social · 19/12/2024
Protesting budget cuts for research and education in Berlin! #SaveBrainCity
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Sawitzki Lab @sawitzkilab.bsky.social · 26/11/2024
Congratulations to Julia Stein for earning her Dr.rer.nat. degree from the @freieuniversitaet.bsky.social with a stellar PhD defence last week! Well done, Dr. Stein! 🎓 #Immunosky #PhD #SciSky
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Sawitzki Lab @sawitzkilab.bsky.social · 25/11/2024
Very exciting week for Sawitzki Lab! 🎉 We moved into brand-new lab spaces at the Rahel Hirsch Center for Translational Medicine (BIH & Charité). Plus, we made the leap to Bluesky! 🚀
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