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Lukas A. Basedow, PhD

@labasedow.bsky.social
1.1K followers 1.1K following 362 posts

Postdoc & Clinical Psychologist @unimarburg.bsky.social‬ & @SFB-TRR-289.bsky.social Interested in development of drug use, drug use disorders, and developmental consequences of drug use. All views my own.

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Reposted by Lukas A. Basedow, PhD
Bratislav Misic @misicbata.bsky.social · 25/09/2026
Spatial organization of AQP4 water channel expression in the human brain | doi.org/10.1126/scia... Aquaporins are a key component of the glymphatic system. How are they distributed + how do they relate to brain function and dysfunction? ⤵️
doi.org
Spatial organization of AQP4 water channel expression in the human brain
Aquaporin-4 (AQP4) water channels support the glymphatic system, a brain-wide pathway that clears cerebral waste products. Here, we use AQP4 gene expression to reconstruct a whole-brain glymphatic-rel...
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Reposted by Lukas A. Basedow, PhD
Mike Jay @mikejay.bsky.social · 27/09/2026
aeon.co/essays/a-sci...
aeon.co
A scientist’s search for answers about Amanita muscaria gummies | Aeon Essays
When I found the mushroom Amanita muscaria being sold in candy wrappers, I uncovered legal loopholes, dangerous dosages and more
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Reposted by Lukas A. Basedow, PhD
Rosalind McAlpine @rosmcalpine.bsky.social · 26/09/2026
We're now recruiting UCL MRes/MSc students (eg Cog Neuro / Brain Sciences) for the 2026/27 academic year to join several research projects involving psilocybin and nitrous oxide. If you're a student on one of these programmes and would like to find out more, email ucjurgm@ucl.ac.uk or dm here 😊
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Reposted by Lukas A. Basedow, PhD
Nicole Rust @nicolecrust.bsky.social · 26/09/2026
I'm so impressed with all that's going on at @sinaibrain.bsky.social. Here are 5 highlights. 1. @bshev.bsky.social ++ are measuring dopamine and serotonin *in living human brains* and using them to predict treatment outcomes. Wow. www.biorxiv.org/content/10.6...
Dopamine and serotonin transients predict depressive symptom relief following deep brain stimulation of human subcallosal cingulate cortex
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Reposted by Lukas A. Basedow, PhD
Siri Leknes @sirileknes.bsky.social · 23/09/2026
Ever had opioids & enjoyed them? Our work shows you might be a minority- or the enjoyment stemmed from pain relief? We compared preoperative opioid effects (RCT, N=199, little pain) & found: 🟥 LARGE effects on drug high/sedation/dizziness 🔸SMALL effects on well-being www.cell.com/cell-reports...
cell.com
Intoxication and other subjective effects of preanesthetic opioids in surgical patients: A randomized controlled trial
Karlsen et al. show that patients experience marked undesirable effects but minimal desirable effects after preoperative intravenous opioids.
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Reposted by Lukas A. Basedow, PhD
Shawn Prest @shawnprest.bsky.social · 22/09/2026
How do advanced meditators deconstruct experience? Happy to announce that the peer-reviewed version of Towards an Active Inference Account of Deep Meditative Deconstruction is now out open access in Neuroscience of Consciousness @nconsc.bsky.social - work with @kevinberryman.bsky.social🧵
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Reposted by Lukas A. Basedow, PhD
Doc Impossible @impossiblephd.bsky.social · 21/09/2026
*Frothing at the mouth with excitement* HEY GUESS WHAT, YOU DON'T HAVE ONE BRAIN, YOU HAVE TWO! med.stanford.edu/news/all-new...
med.stanford.edu
Human brain is two separate organs, Stanford Medicine-led research finds
Stanford Health Care delivers the highest levels of care and compassion. SHC treats cancer, heart disease, brain disorders, primary care issues, and many more.
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Reposted by Lukas A. Basedow, PhD
paolo @paolopalma.bsky.social · 20/09/2026
Working on a new taxonomy for research methods
Punt square with rows depicting data collection (fun, not fun) and columns depicting data analysis (fun, not fun)

Qual interviews are listed as fun to collect and not fun to analyze while surveys are listed as fun to analyze but not fun to collect
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Reposted by Lukas A. Basedow, PhD
Tom Rodebaugh @drrodebaugh.bsky.social · 18/09/2026
New from my lab! So, you've heard that habituation during exposure doesn't predict overall treatment change. Emotional processing theory must be wrong and we need a new theory. But... what if the measurement of habituation was unreliable? Free for 50 days link: authors.elsevier.com/c/1noIo39qZA...
The "always has been" theme with the first astronaut saying "Wait it's all measurement" ("Always has been")
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Reposted by Lukas A. Basedow, PhD
paolo @paolopalma.bsky.social · 18/09/2026
What value are you actually bringing as a mentor if you do this. It would’ve been more helpful to not say anything
Screenshot of Reddit post.

Title: PI will not stop using Grok for revising
*MY* papers

Text: My Pl (a respected, tenured STEM faculty at an R1) will not stop using Grok for everything and I feel like I'm losing my mind. I'm defending in a few weeks and am in the last minute rush to get everything edited, formatted, and submitted to the university for content review. One week before my goal date to send everything to my committee to review, Pl emails me a 10 page Grok thread wherein PI shared my last chapter and associated tables/figures and asked it to find errors and suggest revisions. Grok did find 2 valid technical errors I made in my analysis, but also suggested replacing several of the major analyses with different approaches and adding 3 more major analysis steps (one of which I don't have the data to perform). PI emailed me saying that they'll approve my chapter once I make all the changes Grok requested. None of this makes any sense because PI has been aware of the main research questions, methods, and results for this project for at least the last 7 months- and now all of a sudden there are major, fatal flaws that weren't there before.
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Reposted by Lukas A. Basedow, PhD
Melanie Fischer @melaniefischer.bsky.social · 18/09/2026
Bewerbungen sind noch bis zum 27.9. möglich. Bei Fragen gern bei mir melden!
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Reposted by Lukas A. Basedow, PhD
Kevin Kelley @kevinkelley.bsky.social · 16/09/2026
1/ I have long dreamed of systems that could causally model human neurobiology across scales, from molecular to behavioral. In @nature.com, delighted to share our efforts at creating xenocortical mice where human organoids grow to occupy most of mouse cortex.
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Lukas A. Basedow, PhD @labasedow.bsky.social · 16/09/2026
...
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Reposted by Lukas A. Basedow, PhD
Tom Rodebaugh @drrodebaugh.bsky.social · 15/09/2026
I'll be reviewing applications for a new student or two for UNC-CH's clinical psychology PhD program! Social anxiety, pain, intensive longitudinal data, all that fun stuff. What prospective applicants get if they email me (so no need): docs.google.com/document/d/1... Lab: tarheels.live/rodelab/
tarheels.live
Welcome to the Rodebaugh Lab Website - Rodebaugh Laboratory
Welcome to the Rodebaugh lab website! Here you can learn about what Dr. Rodebaugh & colleagues are working on and what research is being conducted.
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Reposted by Lukas A. Basedow, PhD
Kieran Healy @kjhealy.co · 15/09/2026
Art Stinchcombe (1997).
The guts of institutions is that somebody somewhere really cares to hold an organization to the standards and is often paid to do that. Sometimes that somebody is inside the organization, maintaining its competence. Sometimes it is in an accrediting body, sending out volunteers to see if there is really any algebra in the algebra course. And sometimes that somebody, or his or her commitment, is lacking, in which case the center cannot hold, and mere anarchy is loosed upon the world.
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Alaina Jaster, PhD @jasteralaina.bsky.social · 15/09/2026
Xylo Bio has moved up! We’ve begun our first-in-human Phase 1 clinical trial assessing XYL-1001, a selective 5HT2A agonist, in healthy volunteers! www.prnewswire.com/news-release...
prnewswire.com
Xylo Bio Achieves Clinical-Stage Milestone with XYL-1001, a Highly Selective Neuroplastogen Targeting Major Depressive Disorder
/PRNewswire/ -- Xylo Bio, a clinical-stage biotechnology company developing novel neurotherapeutics for psychiatric and neurological disorders, today announced...
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Reposted by Lukas A. Basedow, PhD
Society for the Study of Addiction @addiction-ssa.org · 11/09/2026
With the retirement of Professor Rainer Spanagel at Addiction Biology after more than two decades, there is an exciting opportunity to lead this scientific journal into a new era. Apply to be Editor-in-Chief by 8 October: www.addiction-ssa.org/about/people...
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Reposted by Lukas A. Basedow, PhD
Goldstein (still not a pseudonym) @goldstein.latinsky.app · 11/09/2026
That sentiment is exactly contrary to what universities advertise. Unis themselves have very deliberately marketed themselves as an essential part of capitalist success rather than as a valuable goal independent of capitalism altogether.
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Reposted by Lukas A. Basedow, PhD
Shannon Vallor @shannonvallor.bsky.social · 10/09/2026
the whole point for me of becoming an academic was to get to spend my life reading the thoughts of other weird little minds, and helping those other weird little minds find their own way, and AI has largely stolen that from me, and I will never be okay with it.
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Ioana A. Cristea @ioanaacristea.bsky.social · 08/09/2026
Our atlas of psychotherapy lists, for six major mental disorders, the unique psychological treatments studied in randomized trials, with protocol/manual references. You can also search by therapy macro-family, like CBT. ioanaalina.github.io/Psychotherap... Paper: pubmed.ncbi.nlm.nih.gov/42457338/
ioanaalina.github.io
Atlas of Psychological Interventions for Severe Mental Disorders
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Lukas A. Basedow, PhD @labasedow.bsky.social · 06/09/2026
Another week of great science and interesting papers:
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Reposted by Lukas A. Basedow, PhD
Nicole Rust @nicolecrust.bsky.social · 04/09/2026
The superposition of these two studies — both incredible — reflect a snapshot of "one big thing" systems neuroscience has yet to resolve. In mice: 1. Task-related signals are everywhere. 2. Absent large swaths of "everywhere," suprisingly sophisticated learning & behavior remains.
Post by Enny van Beest, "Brainwide representation of navigation"Post by Jieyu Zheng, "How fast can mice learn complex mazes?"
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Reposted by Lukas A. Basedow, PhD
Julia M. Rohrer @dingdingpeng.the100.ci · 05/09/2026
Fun little game in which a human life is randomly drawn for you. I ended up a girl, born in the Yangtze Basin in 670 CE. Died in infancy at 6 months 🥲 anyhumanever.com
anyhumanever.com
Any Human Ever
One life, drawn at random from all who have ever lived.
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Lukas A. Basedow, PhD @labasedow.bsky.social · 03/09/2026
Absolut lesenswert!
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Reposted by Lukas A. Basedow, PhD
Hannah R Snyder @hannahrsnyder.bsky.social · 02/09/2026
Saying yes to collaborations: A love story 🧵 Inspired by a conversation w/ one of my grad students today about if she should take on a collaboration. We focus a lot on learning to say no (there are even punch cards) but IMO learning to say yes to the right things is equally important. . .
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Lukas A. Basedow, PhD @labasedow.bsky.social · 02/09/2026
Can't wait to dig into this. Definitely a step forward that's direly needed for addiction/drug use research! Now all we need is to repeat this for all other drugs of choice and their combinations 😁
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Reposted by Lukas A. Basedow, PhD
Joe Bak-Coleman @jbakcoleman.bsky.social · 02/09/2026
This is a wonderful philosophy and applies well to peer review requests.
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Reposted by Lukas A. Basedow, PhD
Melanie Fischer @melaniefischer.bsky.social · 01/09/2026
Wir suchen Verstärkung für unser Team zum Aufbau eines Ambulanzbereichs für Psychotherapie mit Paaren/Familien und Paartherapie. Gerne mit Interesse, im Rahmen einer unbefristeten Stelle diesen Bereich im schönen Marburg langfristig mitzugestalten. Ich freue mich sehr darauf! Mehr👇🏻
stellenangebote.uni-marburg.de
Wissenschaftliche*r Mitarbeiter*in und Psychologische*r Psychotherapeut*in
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Reposted by Lukas A. Basedow, PhD
Darren Dahly @statsepi.bsky.social · 01/09/2026
How fast to things change in academia? I wrote this as a new lecturer in 14 years ago, clearly optimistic about how web 2.0 would change scientific publishing, but it's only gotten much, much worse. darrendahly.github.io/post/2012-02...
darrendahly.github.io
How can we fix scientific publishing? |
Principal Statistician | Senior Lecturer
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Reposted by Lukas A. Basedow, PhD
Eric Schares @eschares.bsky.social · 31/08/2026
🚨Update: Our analysis of global APC expenditure has now been expanded to cover more publishers (7 -> 14) and more years (2019-2025). We estimate $15B in APCs paid over seven years, $3.7B in 2025 alone. Elsevier crosses the $1B threshold by itself in 2025. arxiv.org/abs/2608.16322 #ScholComm
Line chart showing 5 biggest publishers from 2019-2025
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Reposted by Lukas A. Basedow, PhD
Nico Schuck @nicoschuck.bsky.social · 24/08/2026
I enjoyed writing this piece for The Transmitter. AI is a seismic change for science. What we make of it is up to us, but it’s a decision we can only make collectively. I hope more labs, and the field at large, will engage in finding a shared view of how we want to use AI.
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Reposted by Lukas A. Basedow, PhD
Fred Barrett @fredbarrettphd.bsky.social · 31/08/2026
Excited to share our new paper in Psychopharmacology: A pilot study comparing high-dose oral Δ9-THC, psilocybin, and placebo under the same set and setting used in psychedelic clinical trials. @jhpsychedelics.bsky.social 🧵 link.springer.com/article/10.1... 1/n
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Lukas A. Basedow, PhD @labasedow.bsky.social · 31/08/2026
A bit late, but I did get to read some nice stuff last week! Here we go:
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Julia M. Rohrer @dingdingpeng.the100.ci · 29/08/2026
“Academia, if you’re a piece of shit, is so easy“ 😭
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samuel mehr @mehr.nz · 28/08/2026
I am currently recruiting for a 2-year postdoc/research fellow role at the University of Auckland here in New Zealand, focusing on auditory perception, hearing, and music in older adults, including people with Alzheimer's disease or other dementias ~NZ$100k/yr, flexible start date, please apply!
forms.gle
Postdoc in The Music Lab // Expression of interest
Note. The below text is a general overview of the sorts of postdocs we often recruit. We are currently recruiting candidates for a 2-year position focusing on auditory perception in aging populations,...
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Reposted by Lukas A. Basedow, PhD
Josh Grubbs @joshuagrubbsphd.com · 28/08/2026
1/43 Ok folks, after much teasing and anticipation, I'm THRILLED to share our new paper in Annual Review of Clinical Psychology. Not gonna lie: I'm proud of this one, and I hope it makes an impact on the field (so please share!). A thread 🧵👇
To Be a Mental Disorder: Revisiting Behavioral Addictions
Joshua B. Grubbs, * Nicholas C. Borgogna,  Beáta Bőthe,  Hyoun S. Kim,  Rory A. Pfund,  Shane W. Kraus 

Manuscript to appear in the 2027 edition of Annual Review of Clinical Psychology, this preprint may not
exactly represent the final printed copy.

Grubbs, J.B., Borgogna, N.C., Bőthe, Beáta, Kim, H.S., Pfund, R.A., & Kraus, S.W. (2027) To Be a Mental Disorder: Revisiting Behavioral Addictions. Annual Review of Clinical Psychology. 10.1146/annurev-clinpsy-061225-045608

Behavioral addictions have been recognized in various forms for centuries, yet only three—Gambling Disorder, Gaming Disorder, and Compulsive Sexual Behavior Disorder—are currently included in formal diagnostic systems. In the past decade, research on these conditions has expanded dramatically in both volume and methodological rigor, drawing on longitudinal, neurobiological, and cross-cultural designs and evolving into a truly global science. Even so, the field remains beset by unresolved controversies. Chief among these is a persistent tendency to import substance use disorder concepts—tolerance, withdrawal, and dependence—that lack conceptual and empirical support when applied to behavior. Related challenges concern the over-pathologizing of normal engagement and a reliance on confirmatory, self-report measurement of uncertain validity. We argue that advancing the field requires sustained funding, theory grounded in the disorders themselves, objective and intensive-longitudinal methods, greater diversity, and public health and regulatory attention to increasingly technological environments.
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Zachary Cohen @depressionlab.bsky.social · 21/08/2026
Excited this measurement manuscript is out. 6+year effort to address what we saw as limitations in how we use the PHQ-9. Work by @dawsonhaddox.bsky.social in collabo w my partner in (measurement) crime @eikofried.bsky.social. If you use PHQ for weekly assessment or symptom-level analyses, read this!
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Colette Delawalla, PhD @cdelawalla.bsky.social · 22/08/2026
This was a fun interview! (Written in German but the translation via safari is pretty accurate!)
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Lukas A. Basedow, PhD @labasedow.bsky.social · 23/08/2026
This week I did not read any science but related to recent events I recommend this article from the Guardian: www.theguardian.com/world/2024/o... and the incredible reporting by @hopenothate.org.uk: investigations.hopenothate.org.uk/race-science...
theguardian.com
Revealed: International ‘race science’ network secretly funded by US tech boss
Group promoting ‘dangerous’ scientific racism ideology teamed up with rightwing extremist, recordings reveal
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The Power of Expectations @sfb-trr-289.bsky.social · 22/08/2026
Today is the last Meet the Scientist event aboard the #MSWissenschaft and one of our emerging PIs, Marcel Wilhelm from @unimarburg.bsky.social, is there to answer all of your questions! ✨ 10:00-15:00 in Mainz! ms-wissenschaft.de/de/veranstal... @w-i-d.de
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Berna Devezer @devezer.bsky.social · 21/08/2026
I truly don't get the point of peer reviewers using AI to review a paper. If the authors need generic comments or simple error checks, they can use AI themselves. If the journal/editor needs it, they can do the same. What is the point of asking a peer reviewer to ask AI? Setting all other objections
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Philipp Kanske @kanske.bsky.social · 19/08/2026
Interessiert an einer Promotions- oder PostDoc-Stelle in clinical social neuroscience? Wir sind ein kooperatives, internationales Team👇 an der @tudresden.bsky.social und suchen Verstärkung für Lehre und Forschung im @trr393.bsky.social Danke für's Teilen! www.verw.tu-dresden.de/StellAus/ste...
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Matteo Carandini @carandinilab.net · 17/08/2026
I am proud of this paper. Since it came out in 2022 it has received 0 citations (yes that's a zero). But multiple young scientists have found it useful! (from other labs, so they were not coerced...). Perhaps you will find it useful too? SOME TIPS FOR WRITING SCIENCE doi.org/10.1523/ENEU...
doi.org
Some Tips for Writing Science
When preparing a scientific paper, we typically write with coauthors who have different backgrounds and styles, and we target readers who have little time and patience. To help both readers and writer...
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Lukas A. Basedow, PhD @labasedow.bsky.social · 16/08/2026
I had already finished half the thread when I accidentally closed bluesky... So only the second half of my resting list today. New phone and all...
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megan peters 🧠 @meganakpeters.bsky.social · 12/08/2026
Spot on and well worth a read. And another reason why we shouldnt let AI do science for us: if we always do the most expected analysis or experiment, we very well may miss the thing that could make all the difference.
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Michel Nivard @michelnivard.bsky.social · 12/08/2026
You can quibble with the details, but this is a great description on how algorithms flatten media, shopping, music, etc… I’d add that this is also why algorithms induce gender differences in consumption/offerings. Given initially gender/age is all they know we get pushed into a bimodal world.
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Thole Hoppen @tholehoppen.bsky.social · 10/08/2026
🧵 1/7 Are psychological treatments for children and adolescents with PTSD safe? We just published a new systematic review and meta-analysis looking specifically at this question. We brought together evidence from 72 randomized controlled trials involving 5,677 young people. Here’s what we found👇
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Daniel Deimel @ddeimel.bsky.social · 03/08/2026
Drug Checking als Strategie der Schadensminimierung für Drogenkonsument*innen – Ein narratives Review zur Versorgungspraxis und Evidenz. Unsere aktuelle Veröffentlichung: www.thieme-connect.com/products/ejo...
thieme-connect.com
Thieme E-Books & E-Journals -
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Daniel Deimel @ddeimel.bsky.social · 07/08/2026
Warum Solidarität mit Drogenkonsument*innen zur Entstigmatisierung beiträgt... www.instagram.com/reel/DbsH8wL...
instagram.com
Instagram
Create an account or log in to Instagram - Share what you're into with the people who get you.
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Lukas A. Basedow, PhD @labasedow.bsky.social · 09/08/2026
Not quite as much resting as some other weeks but still found some interesting bits and have some cool papers lined up for next week as well:
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