À l’occasion du 8 mars 2026,  la parole est aux deux lauréates du prix Forcheurs – Jean-Marie Lehn 2025 : Eva Kowalinski et Stefanie Kaiser. Ce prix, proposé en partenariat avec l'Université franco-al...

Global warming leads to rising temperatures, necessitating organismal adaptation at the cellular level. One potential mechanism for maintaining proteo…

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Phosphodiester groups occur ubiquitously in nature, e.g. in nucleic acids or in cyclic (di-)nucleotides important for signal transduction. Proteins often use polar or positively charged amino acids t...

Abstract. Modifications of RNA, known as the epitranscriptome, affect gene expression, translation, and splicing in eukaryotes, with implications for devel

Besides the abundant ribosomal and transfer RNA transcripts (rRNA and tRNA, respectively), there are tens of thousands of long coding (mRNA) and non-coding transcripts (lncRNA) within each cell whose ...

RNA modifications are essential for the regulation of cellular processes and have a key role in diseases, however, the differentiation between isomers of nucleosides remains a major challenge in the a...

Abstract. Recent studies have investigated RNA modifications in response to stressors like chemical agents, including the anticancer drug 5-fluorouracil (5

Activation of CD8+ T cells necessitates rapid metabolic reprogramming to fulfill the substantial biosynthetic demands. This article highlights the tRNA m1A

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YTHDF2 modulates oncogenic transformation and immune evasion across multiple B cell cancers by stabilizing m5C-modified mRNAs and destabilizing m6A-modified mRNAs, thereby serving as a dual reader for...