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RNA Society Journal

@rnajournal.bsky.social
251 followers 1 following 210 posts

The official journal of the RNA Society. Featuring cutting edge research in RNA biology. rnajournal.cshlp.org

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RNA Society Journal @rnajournal.bsky.social · 25/09/2026
We used CRISPR-Cas9 to generate human VTRNA1 knockout cell lines, and we found that these deletions caused increased expression from the VTRNA2 locus bit.ly/4wXSKHf
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RNA Society Journal @rnajournal.bsky.social · 24/09/2026
Stress-induced antisense RNAs promote sense–antisense duplex formation, increasing RNA stability while repressing translation through reduced ribosome engagement in Plasmodium falciparum bit.ly/4gAcRp4
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RNA Society Journal @rnajournal.bsky.social · 23/09/2026
Understanding the drivers of specificity for modular RBPs is complex. Here, we dissect the RNA-binding specificity of HNRNPR, and reveal contributions from both disordered and well-folded domains bit.ly/4gvEjnO
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RNA Society Journal @rnajournal.bsky.social · 22/09/2026
In Lactobacillus casei, the AUA codon is decoded predominantly by tRNA-Ile(UAU), whereas lysidine-containing tRNA-Ile(LAU) contributes little because of its low aminoacylation level #RNA #tRNA bit.ly/3UmlWua
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RNA Society Journal @rnajournal.bsky.social · 21/09/2026
R2 retrotransposons propagate in genomes across the animal kingdom. The R2 protein reverse transcriptase (RT) uses an RNA template to synthesize complementary DNA directly into the genome bit.ly/4gmmKI1
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RNA Society Journal @rnajournal.bsky.social · 18/09/2026
(A) RprA binds to two sites on its target hdeD mRNA and represses its translation without inducing mRNA degradation. (B) RprAmut3B, carrying two mutations, binds to a single site on hdeD and gains the ability to initiate hdeD mRNA degradation bit.ly/4qKfw47
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RNA Society Journal @rnajournal.bsky.social · 17/09/2026
SERIPH, a two-step RNA preparation method, separates RNAs by extractability to enrich semi-extractable RNAs underrepresented in conventional preparations bit.ly/4y3QOxQ
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RNA Society Journal @rnajournal.bsky.social · 16/09/2026
Cleavage specificity of E. coli YicC endoribonuclease bit.ly/4zX1QXM
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RNA Society Journal @rnajournal.bsky.social · 15/09/2026
We characterise KP32 RNAP for the production of RNA in vitro. We show increased production of saRNA, mRNA and superior utilisation of non-standard initiating dinucleotides, relative to T7 RNAP bit.ly/4A0nXg3
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RNA Society Journal @rnajournal.bsky.social · 14/09/2026
ArfB rescues stalled ribosomes by hydrolyzing peptidyl-tRNA. His62 is required for efficient hydrolysis but not ribosome binding, revealing a post-binding step in ribosome rescue bit.ly/4wQdSz6
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RNA Society Journal @rnajournal.bsky.social · 11/09/2026
A systematic evaluation of the sources of non-uniform coverage in RNA-Seq and limitations of current practices bit.ly/3Se2ZJx
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RNA Society Journal @rnajournal.bsky.social · 09/09/2026
4MRNA is a new program that creates diverse models through parameter editing to overcome the difficulty of nucleic acid molecular replacement caused by the lack of suitable models bit.ly/4c9aY1e
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RNA Society Journal @rnajournal.bsky.social · 08/09/2026
BRCA1-mutant breast cancers overexpress HORMAD1 and show MEK inhibitor resistance. Targeting RBM38-mediated HORMAD1 exon 4 splicing enhances therapeutic sensitivity. bit.ly/4wWGtmK
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RNA Society Journal @rnajournal.bsky.social · 04/09/2026
PCanPIE self-splices at 25°C, 6 mM Mg2+, avoiding the heat step of prior permuted intron exon (PIE) systems, to efficiently generate circRNAs bit.ly/4xof0Lr
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RNA Society Journal @rnajournal.bsky.social · 03/09/2026
Optimized tRNA structure–seq reveals robust tRNA secondary structures in S. cerevisiae under mild stress conditions bit.ly/3SERb2W
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RNA Society Journal @rnajournal.bsky.social · 02/09/2026
A wave-pinning model for chromosomal silencing induced by long noncoding RNAs connects regulatory feedback loops to patterns of silenced and escaped regions. #ncRNA #MathBio bit.ly/4wsvwcl
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RNA Society Journal @rnajournal.bsky.social · 01/09/2026
Inhibitory codon pairs slow translation and reduce expression in yeast. The inhibitory pair CGA-CGA effects inhibition through ribosome collisions mediated by Hel2, Gcn1 and Mbf1. However, the inhibitory pair CUC-CCG and other inhibitory pairs are not controlled by Hel2, Gcn1 or Mbf1 bit.ly/3QTFzbK
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The Tor pathway, ribosome concentration, and wobble decoding mediate inhibitory effects of the Leu-Pro CUC-CCG codon pair in Saccharomyces cerevisiae.
A monthly journal publishing high-quality, peer-reviewed research on all topics related to RNA and its metabolism in all organisms
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RNA Society Journal @rnajournal.bsky.social · 31/08/2026
EF-P inhibits alpha-hydroxy acid incorporation. Employing EF-P-insensitive and EF-P-responsive tRNAs for alpha-hydroxy acids and npAAs, respectively, bypasses this inhibition to enable depsipept bit.ly/4hh84dT
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RNA Society Journal @rnajournal.bsky.social · 28/08/2026
Eukaryotic Pus4 modifies diverse RNA structures more robustly than its bacterial homolog TruB. TruBΔPUA exhibits a further reduction in pseudouridylation on most non-tRNA substrates bit.ly/4wL8eii
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RNA Society Journal @rnajournal.bsky.social · 27/08/2026
An amino acid exchange in SRRM2 disrupts its interaction with other proteins and affects synapse gene expression - uncovering a new genetic cause of multisystem proteinopathy. #RNAbiology #RareDisease bit.ly/3Rk3GjL
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RNA Society Journal @rnajournal.bsky.social · 26/08/2026
Comparative analysis of the m6A epitranscriptome in HeLa-expressed HPV18 early transcripts reveals its potential impact on splicing bit.ly/4poXh3z
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RNA Society Journal @rnajournal.bsky.social · 25/08/2026
Combined in-vitro and in-silico approach of NMR and MD to study the dynamic conformations of two GNRA tetraloops, enables experimental based ensembles @schwalbe-lab.bsky.social @lindorfflarsen.bsky.social bit.ly/3SReUN9
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Integrated NMR/MD investigation reveals differences after reweighting in conformational ensembles of GAAG and GCAA tetraloops
A monthly journal publishing high-quality, peer-reviewed research on all topics related to RNA and its metabolism in all organisms
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RNA Society Journal @rnajournal.bsky.social · 24/08/2026
Similar rRNA 2′-O-methylation patterns in cytosolic and ER-associated ribosomes suggest these modifications are not major determinants of ER-localized translation. #LundLab #BRIC #UCPH bit.ly/4vQcNYp
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RNA Society Journal @rnajournal.bsky.social · 21/08/2026
Tral maintains P-body composition and transcript-specific mRNA storage by coupling nuclear actin-dependent transcription to selective mRNA retention and stability in D. melanogaster nurse cells bit.ly/44Oc6TF
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RNA Society Journal @rnajournal.bsky.social · 20/08/2026
RDE-4 stabilizes and enhances catalytic activity of the antiviral complex through distinct domain functions; dsRBM3 directly interacts with DCR-1, while dsRBM2 engages dsRNA bit.ly/3R7DubY
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RNA Society Journal @rnajournal.bsky.social · 19/08/2026
High-throughput experimental validation of novel hairpin ribozymes bit.ly/4p5W7tu
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RNA Society Journal @rnajournal.bsky.social · 18/08/2026
Ectopic NOVA1 expression in breast tumors elicits a conserved neuronal splicing program, producing CNS-like isoforms in cytoskeletal, adhesion, and migration genes in parallel with poorer prognosis bit.ly/4grUgNn
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RNA Society Journal @rnajournal.bsky.social · 17/08/2026
Erdmann et al. observe abundant ADAR expression and activity in the germline. Loss of ADAR causes misexpression of ribosome components and other RNAs, which are buffered at the translational level bit.ly/4dHwmfe
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RNA Society Journal @rnajournal.bsky.social · 14/08/2026
Nuclear basket subunits Nup211 and Rsm1 influence RNA 3′-processing and transcription termination in fission yeast bit.ly/439pCAz
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RNA Society Journal @rnajournal.bsky.social · 12/08/2026
MIRNAPEX predicts microRNA changes by integrating target gene expression with 3'UTR isoform usage, linking alternative polyadenylation-driven target-site remodeling to microRNA abundance. #microRNA bit.ly/4fA9eAH
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RNA Society Journal @rnajournal.bsky.social · 11/08/2026
Cancer-Associated Synonymous TP53 Mutations (CASM34) disrupt signal-induced mRNA folding and selectively differentiate p53 activity in DNA damage response bit.ly/4nVsvhP
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RNA Society Journal @rnajournal.bsky.social · 10/08/2026
Single-cell RNA-seq reveals robust, neuronal subtype-specific ribosomal protein mRNA expression signatures in mice brain. #Ribosome #scRNAseq #Neuro bit.ly/436flFf
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RNA Society Journal @rnajournal.bsky.social · 07/08/2026
Unique tryptophan residues (3W) of TTP act with CNOT10 to reduce ARE-containing mRNA accumulation by processing nuclear post-transcriptional mRNA maturation rather than through cytoplasmic mRNA decay bit.ly/4vjCFLU
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RNA Society Journal @rnajournal.bsky.social · 06/08/2026
How RNA-seq library characteristics influence alternative splicing analysis: We show how both longer reads and higher read depth improve the detection, quantification, and classification of alternative splicing bit.ly/43BRP35
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RNA Society Journal @rnajournal.bsky.social · 04/08/2026
lncRNAs regulate gene expression by forming RNA•DNA:DNA triplexes. NMR spectroscopic exchange rate analysis reveals thermodynamic parameters of the Watson-Crick base pair opening, uncovering how antiparallel triplex formation by HIF1α-AS1 RNA modulates Adrenomedullin DNA stability bit.ly/4fhoC4O
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RNA Society Journal @rnajournal.bsky.social · 03/08/2026
We propose the sequence of the nascent transcript influences the processivity of RNAP II transcription via Hrp1. Hrp1 bound to the RNAP II elongation complex increases processivity. Hrp1 bound to RNA bit.ly/49zoJoC
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RNA Society Journal @rnajournal.bsky.social · 03/08/2026
A genome-independent LC-MS/MS approach selectively detects modified oligonucleotides, overcoming traditional sequence-dependent limits. #tRNAModifications #RNAModificationMapping #LCMSMS bit.ly/4o1oqJ1
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RNA Society Journal @rnajournal.bsky.social · 30/07/2026
F. tularensis ribosomes contain 1 of 3 bS21 paralogs. We found that stability and translation of the bS21-2 mRNA, rpsU2, are controlled post-transcriptionally and depend on the mRNA leader sequence bit.ly/49yDqrT
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RNA Society Journal @rnajournal.bsky.social · 29/07/2026
4SeUTP (yellow color) was first synthesized, and recognized by T7 RNA polymerase. The transcribed 4SeU-hammerhead ribozyme facilitates the catalysis likely via the enhanced product releasing bit.ly/3Sc4t6k
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RNA Society Journal @rnajournal.bsky.social · 28/07/2026
Mutations (asterisks) in the multicopy genes for U6 and U4 spliceosomal RNAs are associated with the vision disorder retinitis pigmentosa. Prior studies in yeast suggest a possible mechanism bit.ly/435xfbi
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RNA Society Journal @rnajournal.bsky.social · 24/07/2026
The 3′ UTR isn’t just a tail. Shorter regions boost translation termination, longer ones can hinder it — but structured elements rescue the process by bringing key factors together at the ribosome bit.ly/3QfcEyh
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RNA Society Journal @rnajournal.bsky.social · 22/07/2026
(Left) Reduced ADAR1 heightens type I IFN. (Right) ADAR1 deficiency confers resistance to Plasmodium yoelii despite CD8⁺ T cell loss, with CD4⁺, B, Treg, γδ T and NK cells compensating bit.ly/4nWbFzs
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RNA Society Journal @rnajournal.bsky.social · 20/07/2026
A global view of RNA/DNA interactions in complex 3D structures from PDB, including Leontis/Westhof basepair annotation, pseudoknots, base-backbone interactions, and handling 800+ modified nucleotides bit.ly/4dG6EaX
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RNA Society Journal @rnajournal.bsky.social · 17/07/2026
The pseudouridine synthase Pus4 induces tRNA conformational changes through its catalysis and binding. This study reveals the chronology of these changes using biochemical and biophysical methods bit.ly/4x0O8kX
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RNA Society Journal @rnajournal.bsky.social · 16/07/2026
Human telomerase RNA (hTR) can exist in the full-length form or in a 5’-truncated form. Loss of the 5’ domain can occur through either endogenous RNA processing or antisense oligo-induced degradation bit.ly/4wZvwSo
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RNA Society Journal @rnajournal.bsky.social · 15/07/2026
A method of comprehensive sequencing analysis of the small RNA fragmentome (RiboMarker) bit.ly/4uGk7oX
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RNA Society Journal @rnajournal.bsky.social · 14/07/2026
mRNA COVID-19 Vaccines: Science vs. Misinformation bit.ly/48jPtbN
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RNA Society Journal @rnajournal.bsky.social · 13/07/2026
Pathogen-derived pathoPEPs could mimic plant miPEPs, thereby controlling the expression of plant miRNAs and their target genes, and promoting infection bit.ly/3O2CGUf
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RNA Society Journal @rnajournal.bsky.social · 10/07/2026
Search for known loop motif 3D structures in Rfam with JAR3D bit.ly/41ctfEQ
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RNA Society Journal @rnajournal.bsky.social · 09/07/2026
We interpret global and targeted mouse Exosc10 deletion phenotypes in the context of the gene’s clinical potential as a prognostic cancer biomarker and explore its transcriptional regulatory network bit.ly/41IYUOj
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