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Juan Carvajal Garcia

@jucarvag.bsky.social
135 followers 186 following 73 posts

Ramón y Cajal investigator at the IPBLN-CSIC. My lab studies how bacteria mutate, evolve antibiotic resistance, and repair their DNA. Oviedo->Chapel Hill->Nashville->Granada. No hay que llegar primero, pero hay que saber llegar.

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Reposted by Juan Carvajal Garcia
Ákos T Kovács @evolvedbiofilm.bsky.social · 30/09/2026
The phenotypic landscape of the model firmicute Bacillus subtilis PNAS from Carol A. Gross www.pnas.org/doi/10.1073/...
pnas.org
The phenotypic landscape of the model firmicute Bacillus subtilis | PNAS
Firmicutes are gram-positive bacteria with important roles in human health, disease, and industry. However, more than a quarter of genes in the mod...
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Mark Peifer (He, him) @peiferlabunc.bsky.social · 29/09/2026
For the last 34 years I have been on the faculty of the UNC-Chapel Hill Department of Biology and have never regretted that decision. This year we are hiring TWO new Assistant Professors in the broad area of Molecular, Cell, Developmental Biology 1/n bio.unc.edu
Front page of the website
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Doug Kojetin @dougkojetin.bsky.social · 23/09/2026
Apply today to be my colleague at Vanderbilt in the Department of Biochemistry! 
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EM-electomania.es @electomania.es · 18/09/2026
‼️El ministro de finanzas griego 🇬🇷 aconseja al vicecanciller alemán 🇩🇪 implementar "las reformas necesarias" ✂️ para contener el aumento de la deuda y el estancamiento de la economía Asegura que "inicialmente dolorosas, compensaron a largo plazo". 👇🏻 electomania.es
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Rikki Garner @rikkigarner.bsky.social · 16/09/2026
Excited to announce that the Rikki Garner lab has opened its doors in beautiful Austin, TX! Our interdisciplinary lab @utaustin.bsky.social MBS investigates tissue fluidity as a universal physical regulator of multicellular patterning in health and disease. www.rikkigarnerlab.org 1/n
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Tressie McMillan Cottom @tressiemcphd.bsky.social · 12/09/2026
I’ve either visited or lived in all parts of this country. It is a beautiful place, our ugliness aside. I may be biased but you would be hard-pressed to find a more beautiful state, mile for mile, than North Carolina. Why yes I did just drive through the mountains. Why do you ask??
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Marta Grońska-Pęski @gronskapeski.bsky.social · 09/09/2026
Can dietary interventions change how fast genomes accumulate mutations with age? We studied how caloric restriction (CR)—one of the most robust lifespan-extending interventions—affects somatic mutations across the genome in different tissues and cell types in mice.
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Juan Carvajal Garcia @jucarvag.bsky.social · 04/09/2026
The first time I read about NanoSeq, I thought someone should do this. I’m so glad someone did. I can’t wait to dive in!
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Reyes-Lamothe lab @reyes-lab.bsky.social · 02/09/2026
We’re hiring! The Biology department at McGill is hiring a tenure-track professor in Quantitative Cell Biology. We’re looking for an outstanding researcher and educator to join our community. Deadline: October 9 Info & application: mcgill.wd3.myworkdayjobs.com/McGill_Caree... Please share!
mcgill.wd3.myworkdayjobs.com
Assistant Professor in Quantitative Cell Biology - Department of Biology
Please refer to the How to Apply for a Job (for External Candidates) job aid for instructions on how to apply. If you are an active McGill employee (ie: currently in an active contract or position at ...
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IPBLN-CSIC @ipblncsic.bsky.social · 26/08/2026
🎤 A golpe de bit _ Aquí tenéis la entrevista realizada por RNE a la doctora del @ipblncsic.bsky.social Elena Herrera sobre su investigación en 'tijeras moleculares' que frenan la infección del VIH. 👉 www.rtve.es/play/audios/...
rtve.es
Las 'tijeras moleculares' que frenan la infección del VIH
Conocido como CRISPR-Cas9, se trata de una tecnología que permite cortar, quitar o cambiar partes del ADN de cualquier ser vivo con mucha precisión
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Reposted by Juan Carvajal Garcia
Pablo Alcón @palconh.bsky.social · 21/08/2026
The summer is (almost) over and, as promised, a postdoc position to join our lab is now officially open! Please apply on our website via the link below, or share with your fellow biochemists / structural biologists / DNA repair aficionados! (deadline 30 September) mbg.au.dk/en/news-and-...
mbg.au.dk
Position as postdoc in biochemistry and structural biology of DNA repair - Vacancy at Aarhus University
Vacancy at Department of Molecular Biology and Genetics - Protein Science, Aarhus University
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Juan Carvajal Garcia @jucarvag.bsky.social · 18/08/2026
I had to go home early because of a set of earthquakes. Thankfully everyone seems to be okay. After hurricanes in NC and tornadoes in TN, I thought I was out of reach for natural disasters, but I guess not! Here’s a picture if the aftermath
A trash can and some tubes that fell on the floor in a laboratory
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Juan Carvajal Garcia @jucarvag.bsky.social · 08/08/2026
Unpacking into our new house and I found this. Many happy evenings at He’s not. And many science discussions!
Blue cup from He’s not Here, a bar in Chapel Hill, NC
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AEMET @aemet.es · 05/08/2026
🧵 El verano de 2026 por ahora (junio-julio) es el más cálido de la serie histórica en España, que arranca en 1961. ➡️ Con una temperatura media de 24,5 ºC, supera en 0,7 ºC a los bimestres junio-julio más cálidos, los de 2022 y 2025. Es 2,9 ºC más cálido que el promedio 1991-2020.
Gráfico con la temperatura media en España peninsular para el bimestre junio-julio
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Martin Taylor @mstaylor.bsky.social · 27/07/2026
To what extent is cancer development deterministic? Does the germline genome affect that predictability? We re-ran cancer evolution to answer these questions. www.nature.com/articles/s41...
Phylogenetic tree of four mouse strains illustrating how clonal expansions differ between them following a DNA damaging exposure. Stylistic replay symbol illustrating the re-running of cancer evolution.
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Juan Carvajal Garcia @jucarvag.bsky.social · 16/07/2026
I have my own racks! And they’re new!
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Jose A. Esteban @jaestebancbm.bsky.social · 16/07/2026
Bienvenidas las #Plazas de investigación, los contratos #ATRAE, #RyC, etc. Pero si no se inyecta más dinero en el sistema, eso solo sirve para que se rechacen más proyectos. Y los que se conceden, se quedan con una financiación estancada desde hace 5 años, que no cubre siquiera la inflación. 😠
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Jose A. Esteban @jaestebancbm.bsky.social · 15/07/2026
Muchos ya habréis visto la resolución provisional de los proyectos #PID2025 de la @ageinves.bsky.social Aquí va la distribución. La financiación media por proyecto se ha quedado como el año pasado. Y seguimos con 2/3 de los proyectos con <50 k€ por año. ☹️ www.aei.gob.es/convocatoria...
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adelaide tovar @adel-aide.bsky.social · 11/07/2026
Delighted to share that I’ll be sticking around at Michigan to start my lab in the Department of Human Genetics! Starting in May 2027, the Tovar lab will use functional genomics to study transcription factor biology and regulatory network dynamics in complex disease. Stay tuned for more details…
the author pictured outside her lab building before starting her postdoc (top) and now (bottom)
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Peter Ly @peterlylab.bsky.social · 12/07/2026
Chromosome loss is detrimental to cellular fitness, yet can be one of the earliest events in cancer. How can a deleterious genomic alteration initiate tumorigenesis? 🤔 Our latest preprint tackles this paradox using clear cell renal cell carcinoma (ccRCC) as a model. www.biorxiv.org/content/10.6...
biorxiv.org
A single chromosome 3p break initiates clear cell renal cell carcinoma evolution
Clear cell renal cell carcinoma (ccRCC) is initiated by chromosome 3p loss, yet chromosome losses impose a profound fitness burden on normal cells. How renal epithelial cells tolerate this deleterious...
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Axel Torres @axeltorres.bsky.social · 05/07/2026
Lo de Balogun es un escándalo tan grande como me parece, ¿no?
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McVey lab @mcveylab.bsky.social · 29/06/2026
We teamed with Jim Crott's lab at BU to show that administration of freeze-dried Parabacteroides distasonis extends Drosophila mean lifespan by preventing leaky guts. How? Maybe hormesis. A fun collaboration that features the work of 8 Tufts undergraduates! www.aginganddisease.org/EN/10.14336/...
aginganddisease.org
Lifelong Consumption of Freeze-Dried <i>Parabacteroides Distasonis</i> Improves Gut Barrier Integrity and Extends Lifespan and Health Span in Drosophila Melanogaster.
<p>Chronic inflammation has been shown to be associated with aging. In <i>Drosophila melanogaster</i>, age-related inflammation in the gut results in a disruption of gut barrier integrity, which can l...
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Juan Carvajal Garcia @jucarvag.bsky.social · 23/06/2026
Now published on @narjournal.bsky.social ! academic.oup.com/nar/article/...
academic.oup.com
Processing of reversed replication forks is required for the resolution of replication-transcription conflicts
Abstract. DNA replication and transcription occur simultaneously on the same template, leading to conflicts between the two machineries. Conflicts stall re
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Pablo Alcón @palconh.bsky.social · 23/06/2026
Join us! Postdoc position (2-3 years) in our lab @molbiolau.bsky.social Looking for candidates with experience in cell culture, genome editing, biochemistry, and/or structural biology. Application opens in August via AU's system but informal enquiries by email are welcome from now. (1/2)
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Annie Hatmaker, Ph.D. @annemakerofhats.bsky.social · 03/06/2026
Related: if you know a great undergrad interested in grad school (or if YOU are interested), & they'd like to work in fungal biology using population genomics to study pathogenicity and genome plasticity, please encourage them to reach out! See annehatmaker.com/contact/ for more info on how
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Juan Carvajal Garcia @jucarvag.bsky.social · 10/06/2026
Paper accepted!
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Diedre Reitz @diedrereitz.bsky.social · 09/06/2026
I will be recruiting research technicians and post-bac fellows and accepting rotation students beginning in fall 2027. Please email me or ask to chat at the FASEB Genetic Recombination and Genome Rearrangements meeting in July if you are interested!
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Juan Carvajal Garcia @jucarvag.bsky.social · 08/06/2026
First conference as (almost) PI!
Name tag for the BACELL2026 conference with my name (Juan Carvajal Garcia) and affiliation (Vanderbilt University)
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Juan Carvajal Garcia @jucarvag.bsky.social · 05/06/2026
Today is the last day of 11 magnificent years living in the United States. Today, I move back to Spain. I came as a 22 year old aspiring scientist and I’m coming back with a wonderful wife, and the best scientist I could become. And of course, with little Mango.
A small white dog with his head popping out his dog carrier
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McVey lab @mcveylab.bsky.social · 04/06/2026
Extended abstract deadline (June 7th) for FASEB Dynamic DNA Structures in Scottsdale, AZ July 19-24. Speaking slots still open, and scholarships available for trainees (grad students and postdocs). Let your colleagues know! events.faseb.org/event/Dynami...
events.faseb.org
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Juan Carvajal Garcia @jucarvag.bsky.social · 04/06/2026
Last night out in Nashville
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Jeff Sekelsky @jeffsekelsky.bsky.social · 03/06/2026
Carolyn started this as a whole-genome revisit of the classic 1996 papers on spontaneous nondisjunction from Hawley (Dros X) and Sherman (human 21) labs. She looked at a metacentric (Dros 2) and found that the rules are different - no obvious relationship between ndj and crossovers. Shape matters!
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Juan Carvajal Garcia @jucarvag.bsky.social · 03/06/2026
Last (?) preprint as a postdoc in the Merrikh lab! Awesome collaborative effort with graduate student Oyku! I hope people give it a read!
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bioRxivpreprint @biorxivpreprint.bsky.social · 03/06/2026
Polynucleotide Phosphorylase Stops Replication Restart by Degrading the RNA within R-loops during Replication-Transcription Conflicts www.biorxiv.org/content/10.64898/20…
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Peter Ly @peterlylab.bsky.social · 01/06/2026
The Ly Lab is recruiting two #postdocs to study intercellular DNA transfer. Join us to tackle fundamental questions at the intersection of genome instability, cell-cell communication, and cancer evolution. Please share! 🙏 Full posting: cri.utsw.edu/careers/
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Juan Carvajal Garcia @jucarvag.bsky.social · 30/05/2026
This is beautiful and soccer is wonderful.
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Peter Ly @peterlylab.bsky.social · 19/05/2026
Excited to share our latest paper! We found that large pieces of the human genome can transfer between cells upon direct contact, endowing recipient cells with heritable phenotypic changes. @cp-cell.bsky.social (1/7) www.cell.com/cell/fulltex...
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Ákos T Kovács @evolvedbiofilm.bsky.social · 18/05/2026
is this dataset a candidate for SubtiWiki incorporation, @joergstuelke.bsky.social?
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Quantian @quantian.bsky.social · 14/05/2026
US universities genuinely are like “welcome to Tennessee Agricultural College in Bumfuck Nowheresville. We invented the modern potato and our facilities include a particle accelerator, nuclear reactor, and TOP500 supercomputer. Tuition is $12,000 for instate students and we have 40,000 of them”
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The Castiglione Lab @ Vanderbilt @castiglionelab.bsky.social · 08/05/2026
Excited to drop our visual systems pre-print 10 years in the making. We hacked nature's cheat code to protect the eye from light damage. This unexpectedly also boosts rod sensitivity. Huge thanks to collabs Tonia Rex, @amandalea.bsky.social , Alex Bick, and their labs! @evolutionvu.bsky.social
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McVey lab @mcveylab.bsky.social · 07/05/2026
Abstract deadline approaching (May 24) for FASEB Dynamic DNA Structures in Scottsdale, AZ July 19-24. This is a not-to-miss conference if you're interested in the intersection of nucleic acid structures and human health. Speaking slots still open! Please repost. events.faseb.org/event/Dynami...
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Tyler Weaver @tmweaver.bsky.social · 07/05/2026
My lab is currently hiring at the Research Technician level. This would be a great opportunity for a recent graduate looking to gain additional research experience prior to applying to graduate school! Job ad below: careers.uvahealth.org/us/en/job/R0...
careers.uvahealth.org
Lab Technician 1 or 2 in Biochemistry & Molecular Genetics-Weaver Lab in Charlottesville, Virginia, United States of America | Research at University of Virginia Health System
Apply for Lab Technician 1 or 2 in Biochemistry & Molecular Genetics-Weaver Lab job with University of Virginia Health System in Charlottesville, Virginia, United States of America. Research at Univer...
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Juan Carvajal Garcia @jucarvag.bsky.social · 30/04/2026
MS Word's spell check is reaching unprecedented levels of stupid.
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Men in Blazers Media Network @meninblazers.bsky.social · 12/04/2026
GLASS CEILING SHATTERED 👏 Marie-Louise Eta becomes the first woman appointed to take charge of a men's first team in Europe's top 5 leagues. She will coach Union Berlin for the rest of the Bundesliga campaign 🇩🇪
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Bret Freudenthal @freudlab.bsky.social · 09/04/2026
Abstract deadline approaching (April 15) for the Midwest DNA Repair meeting. Join us for an exciting meeting with outstanding science and valuable networking. Register and share. $100 includes meals, networking, and social events. sites.google.com/view/kumc-mi...
sites.google.com
Midwest DNA Repair
The 25th Annual Midwest DNA Repair Symposium will be held at the University of Kansas Medical Center in Kansas City, Kansas, on May 30–31, 2026. The meeting will take place in the Health Education Bui...
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Evolutionary Studies at Vanderbilt @evolutionvu.bsky.social · 01/04/2026
A sneak peak of one of the pages from the upcoming issue of Evolutionary Studies - the Magazine! Join us for #evolution out in the wild!
Promotional collage for ‘Evolution in the Community.’ Top image shows a museum-style outreach table indoors with a fossil skeleton display, a smiling presenter behind a Nashville Predators-branded table, and a sign reading ‘Fossil Display.’ Text lists upcoming events: April 11 – Nashville Predators Family Night; April 26 – Nashville Earth Day; November 5 – Biodiversity Day at Adventure Science Center. Bottom image shows two people standing at an outdoor booth under a canopy beside a Vanderbilt Evolutionary Studies banner, engaging with a crowd at a community event.
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Matt Hutchings @matthutchings.bsky.social · 16/02/2026
Research into filamentous actinomycetes, the antibiotic producers, is in steep decline. Loads of natural products chemistry research worldwide but not much aimed at understanding their biology and ecology. The latter is key to unlocking their specialised metabolism link.springer.com/article/10.1...
link.springer.com
Revitalizing actinobacteria research: an urgent response to the antimicrobial resistance crisis - Natural Products and Bioprospecting
Abstract The crisis of antimicrobial resistance (AMR) is escalating while the antibiotic pipeline remains stagnant. Our bibliometric analysis of eight decades of literature reveals a critical imbalanc...
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Juan Carvajal Garcia @jucarvag.bsky.social · 27/03/2026
No
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Quentin Smith @qmsmith.bsky.social · 25/03/2026
1/11 In our story out today in @nature.com , we showcase the molecular mechanisms that enable Cas9 to bind and cleave negatively supercoiled ((-)SC) off-targets! 🧬🧵 🔗 www.nature.com/articles/s41... #CRISPR #Cas9 #DNATopology #AFM #CryoEM #SingleMolecule #Biophysics
nature.com
Structural basis of supercoiling-induced CRISPR–Cas9 off-target activity - Nature
Cas9 structures explain&nbsp;topology sensing and off-target activation.
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Agencia Estatal de Investigación @ageinves.bsky.social · 25/03/2026
📣 Lanzamos webinario “Choose Europe, Choose Spain”, con Ministerio de Ciencia, Innovación y Universidades y #FECYT. El objetivo es posicionar a España como destino estratégico para el talento científico internacional. ✏️ horizonteeuropa.es/choose-europ... ℹ️ www.horizonteeuropa.es/espana-impul...
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