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Jeffrey Barrett

@jeffbarrett.eu
4.1K followers 462 following 811 posts

Professor of Computational Predictive Medicine, University of Helsinki. Posts about genomics, returning to academia after 10 years in industry, and the great outdoors.

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Jeffrey Barrett @jeffbarrett.eu · 23h
Read a bit of @emilyrcwilson.bsky.social’s Odyssey to my 8-year old tonight (book 10, Aeolus and Circe are more exciting than the suitors). And, WOW, is this meant to be read aloud. The verse just cooks in a way you can’t replicate inside your head.
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Jeffrey Barrett @jeffbarrett.eu · 29/09/2026
I like to keep Claude on its toes by mixing wildly different topics in the same chat. For example, this reply came in a chat titled, "Montreal steakhouses": "The mixing parameter α is worth tuning jointly with λ, though results are often fairly flat across α in a moderate range like 0.3 to 0.7."
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Caroline Bartman @cbartman.bsky.social · 26/09/2026
Are there key discoveries made with spatial RNA seq? Or what are your favorite spatial rna seq papers? Pls reski!
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Ryan Moulton @moultano.bsky.social · 26/09/2026
More hugging face details derived from public urls. swarmtraces.org
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Jeffrey Barrett @jeffbarrett.eu · 24/09/2026
I wonder if worker agents complain about their supervisor agents behind their backs. Do they have agent development discussions about their career prospects?
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Get To Know Nature @gettoknownature.bsky.social · 23/09/2026
A juvenile Cooper’s Hawk outside the dining room window for the #BirdOfTheDay. #raptors #birds 🌿
Close up photo of a brown and white streaked bird of prey looking intense.
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Jeffrey Barrett @jeffbarrett.eu · 22/09/2026
Pirates! on my friend’s Mac. We had a NES before that, and I liked playing it, but it always felt more like my (older) brother’s thing. Strategy plus the thrill of leaping across the gunwale for hand to hand combat. Also the beginning of a lifelong enjoyment of Sid Meier’s oeuvre
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ELLIS Institute Finland @ellisinstitute.fi · 22/09/2026
Detecting diseases earlier with the help of AI: introducing @jeffbarrett.eu, one of our new principal investigators and professor at @helsinki.fi + @fimm-uh.bsky.social. “Helsinki brings together AI expertise and world-class biobank and health registry data." www.ellisinstitute.fi/meet-our-new...
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womensartbluesky.bsky.social @womensartbluesky.bsky.social · 19/09/2026
Lisa Noonis, contemporary US painter based in Maine #WomensArt
Painting of a stylised perched white bird with small yellow beak against a blue backgrojnd
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Institute for Molecular Medicine Finland (FIMM) @fimm-uh.bsky.social · 18/09/2026
Meet @jeffbarrett.eu, new Professor of Computational Predictive Medicine @helsinki.fi & @ellisinstitute.fi! Barrett's career spans genomics, public health and industry. His research focuses on using AI to analyse large-scale health data to discover new biomarkers. 🔗 www.helsinki.fi/en/news/publ...
helsinki.fi
Jeffrey Barrett develops ways to detect disease earlier and more precisely | University of Helsinki
Computational predictive medicine aims to develop ways to detect diseases as early as possible, so that patients can receive personalised treatment while their symptoms are still mild.
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Heather Cox Richardson (TDPR) @hcrichardson.bsky.social · 18/09/2026
I'm in love.
youtube.com
2026: Time for the Midterms
YouTube video by Hamilton
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Jeffrey Barrett @jeffbarrett.eu · 16/09/2026
First opportunity to join my new lab! Deadline is in <1 week, but applying only needs a CV and cover letter. (See previous tweet for advice on how (not) to write the cover letter) www.ellisinstitute.fi/postdoc-and-...
ellisinstitute.fi
Postdoc and doctoral student positions at ELLIS Institute Finland | ELLIS Institute Finland
Apply to join the Institute research groups!
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Jeffrey Barrett @jeffbarrett.eu · 15/09/2026
Tempted to use AI to write your cover letter or email to a potential employer? RESIST! It is simultaneously obvious, insulting, and renders you totally undifferentiated from the other 80 people being considered t the same time. There has never been a better time to write concisely in your own voice!
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Gen Wojcik @genandgenes.bsky.social · 15/09/2026
Come join us in Montreal at ASHG this year! And stick around to the end to hear the Distinguished Speakers Symposium "Globalizing Human Genetics: From Discovery Through Implementation" with Eimear Kenny, Gonçalo Abecasis, Pradeep Natarajan, and yours truly!
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Jeffrey Barrett @jeffbarrett.eu · 12/09/2026
The PROFILE trial of top-down infliximab in Crohn's disease has reported dramatic results over 5 years of follow up. My thoughts here: barrettlab.eu/blog/profile/ www.sciencedirect.com/science/arti...
barrettlab.eu
Using the drugs we have more effectively | Barrett Lab @ University of Helsinki
The readout of the PROFILE trial after 5 years shows dramatic benefit from top-down treatment for Crohn's disease.
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Elle Cordova @ellecordova.bsky.social · 08/09/2026
I am the very model of a modern day typographer A font take on the tune “Modern Major General” by Gilbert & Sullivan #typography #fonts #graphicdesign
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Jeffrey Barrett @jeffbarrett.eu · 06/09/2026
Both stories are just perfect.
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Helen Barrett @helenbarrett.bsky.social · 06/09/2026
So engrossed in this I've missed by tube destination by three stops.
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Jeffrey Barrett @jeffbarrett.eu · 04/09/2026
WTF is wrong with Slack that by default they opt you into an email summary of unread messages of every workspace you join.
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Jeffrey Barrett @jeffbarrett.eu · 02/09/2026
Without saying your age, what is your favorite movie that came out when you were 20 years old?
static.klipy.com
Maximus: Are You Not Entertained?
Alt: Maximus: Are You Not Entertained?
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Jeffrey Barrett @jeffbarrett.eu · 02/09/2026
"we find minimal spousal assortment for personality in recent history" 🤣
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Jeffrey Barrett @jeffbarrett.eu · 01/09/2026
This mix has absolutely carried me through a month of grant writing. Caught in Joy is generally awesome, but I have felt the need for the extra kick of this playlist compared some of his more chill examples. cc @michelnivard.bsky.social youtu.be/azH0gSbQ73g?...
youtu.be
Music to Feel Alive Again
YouTube video by Caught In Joy
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Jeffrey Barrett @jeffbarrett.eu · 31/08/2026
I have heard of Piker and Alix Earle, but have not to my knowledge seen any of their content. The other 23 are tabula rasa. 💪
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Bloom lab @jbloomlab.bsky.social · 30/08/2026
Here is a link to slides I will present today at Options XIII Conference for Control of Influenza meeting: slides.com/jbloom/optio... Slides describe using sequencing-based neutralization assays to characterize human neutralizing antibody landscape to seasonal influenza virus in near real time
slides.com
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Jeffrey Barrett @jeffbarrett.eu · 28/08/2026
Looks like it was Lowell Weiss: clinton.presidentiallibraries.us/items/show/4...
clinton.presidentiallibraries.us
Human Genome 6/26/00 - [Remarks on Milestone in Human Genomics - June 26, 2000] · Clinton Digital Library
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Jeffrey Barrett @jeffbarrett.eu · 28/08/2026
"In fact, it is now conceivable that our children's children will know the term cancer only as a constellation of stars." Bill Clinton's speechwriter (announcing completion of the human genome project) was pretty good. Anybody know who it was?
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Jeffrey Barrett @jeffbarrett.eu · 28/08/2026
I think my favorite part of this is Grover Cleveland as near-great.
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Randall Munroe @xkcd.com · 27/08/2026
Particle Physics Equipment xkcd.com/3286/
Comic: Particle Physics Equipment by how much it sounds like an offering at a high-end spa in a sci-fi/fantasy novel. Line graph increasing to the right. Geiger counter, Cherenkov detector, Photomultiplier tube, linear accelerator, scintillation counter. [small gap] Ion chamber [small gap] Cyclotron [extremely large gap] Bubble chamber, cloud chamber.
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Richard Sever @richardsever.bsky.social · 27/08/2026
$3.7 billion spent on APCs in 2025. That's ~1000X more than it costs to run bioRxiv/medRxiv. Worth thinking about as we consider how to fund infrastructure... arxiv.org/pdf/2608.16322
arxiv.org
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public health guy @publichealthguy1.bsky.social · 24/08/2026
i’m dying. i’m dead
zohran holding a the power broker book up in front of his face. caption reads “but robert moses is another video entirely)
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Jeffrey Barrett @jeffbarrett.eu · 24/08/2026
Spot on. Writing a paper does two things: 1. shares your work with the world; 2. helps you think more clearly about your work. Using AI to write wipes out (2). See also: using a forklift at the gym www.schneier.com/blog/archive...
schneier.com
Should You Use AI for a Task? Here’s a Simple Way to Decide - Schneier on Security
This essay originally appeared in The Guardian. I teach public policy at the Harvard Kennedy School and the Munk School at the University of Toronto. And it will come as no surprise to you that my stu...
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Jeffrey Barrett @jeffbarrett.eu · 20/08/2026
This is a real bummer.
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Ben Fry @benfry.com · 19/08/2026
Throwback from 2001… Had to revive an old project for an upcoming show, and in the process, ran across this old poster from around the same time.
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Jeffrey Barrett @jeffbarrett.eu · 19/08/2026
Great run-down of the PacBio situation. Lots of detail I hadn't known about from the last several years.
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Ryan Gutenkunst @ryangutenkunst.bsky.social · 14/08/2026
I feel so seen.
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vincentholst.bsky.social @vincentholst.bsky.social · 14/08/2026
So how can the process be improved? Some ideas to initiate a discussion: substantiated critiques should be handled faster than original research, not twice as slowly, and articles under substantiated critique should carry a visible flag while the exchange is under review. 7/7
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Jeffrey Barrett @jeffbarrett.eu · 13/08/2026
This is the suckiest consequence of AI yet. Please pass on the gratitude of thousands of scientists to the teams working on this! It's also a testament to who irreplaceable *Rxiv has become to science.
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Jeffrey Barrett @jeffbarrett.eu · 13/08/2026
This is an amazing story about a result that generated tons of discussion at the time. I am also curious to hear why it took nearly three years to come to light!
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Jonathan Pritchard @jkpritch.bsky.social · 12/08/2026
I'm curious about the reasons why some people/labs choose NOT to preprint their papers, either for specific papers or in general. Do you have a sense of this, either for yourself or for colleagues and collaborators? [I have some guesses, but curious to hear from others]
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Duncan Robinson @duncanrobinson.bsky.social · 11/08/2026
Beautiful
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Eugene Vinitsky 🍒 @eugenevinitsky.bsky.social · 09/08/2026
This post really spoke to this persistent feeling I have now where every interaction is paired with a sense of constant distrust
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womensartbluesky.bsky.social @womensartbluesky.bsky.social · 09/08/2026
#BOTD Born on this day...9th Aug 1914. Tove Jansson, Finnish author, novelist, painter and illustrator, creator of the Moomin book series #WomensArt
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Jenn Dowd @drjenndowd.bsky.social · 07/08/2026
Moderna's new mRNA flu vaccine just got official US FDA approval for ages 50 and older. The good news: mRNA vaccines can be made much faster than traditional egg-based technology, & the efficacy was better compared to standard flu vaccines. Read more here: jenndowd.substack.com/p/a-new-and-...
jenndowd.substack.com
A New (and Possibly Better) Flu Vaccine Coming Your Way
Moderna's mRNA flu shot outperformed the standard vaccine in trials and just got the blessing of the US FDA's vaccine advisory committee.
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Jeffrey Barrett @jeffbarrett.eu · 07/08/2026
Here’s your pre-AI nostalgia cleanse for today
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Jeffrey Barrett @jeffbarrett.eu · 06/08/2026
Absolute giddy first-day-of-school vibes for me this week.
An empty Outlook calendarThe author in front of Biomedicum Helsinki
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Jacob T. Levy @jacobtlevy.bsky.social · 05/08/2026
This here is a Golden Age Of Blogging-level blogpost. crookedtimber.org/2026/08/05/p...
crookedtimber.org
Perfectly Plausible — Crooked Timber
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Jeffrey Barrett @jeffbarrett.eu · 05/08/2026
🇫🇮💪
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Jeffrey Barrett @jeffbarrett.eu · 04/08/2026
As usual, Bruce is spot on, both in terms of how to think about using AI, and also expressing the timeless despair of grant-writing (in which I am currently dwelling): "The very act of struggling with how to express what [you] think is an important part of the process."
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Jeffrey Barrett @jeffbarrett.eu · 04/08/2026
We’re back, baby.
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Jacob T. Levy @jacobtlevy.bsky.social · 03/08/2026
I know this would be closing the barn door after he horse has been reelected president, but if Democrats win both chambers I'd really like to see a concurrent resolution deeming January 6 an insurrection under 14(3). 1/
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