iiinova — where your digital self keeps evolving

Reposted by Alexandre Hervé

Aude Bernheim @audeber.bsky.social · 21/07/2026

Out @cp-cellhostmicrobe.bsky.social, natural products meet bacterial immunity! We used genomics to identify lanthivirins: a family of >2,000 lanthipeptide BGCs that protect Actinobacteria against phages. Led by @hshomar.bsky.social & @mariegllm.bsky.social www.sciencedirect.com/science/arti...

sciencedirect.com

A family of lanthipeptides with anti-phage function

Bacteria produce natural products to adapt to their environments, with phage interactions as major ecological and evolutionary drivers. While some nat…

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Reposted by Alexandre Hervé

Institut Pasteur | 130 years of biomedical research @pasteur.fr · 30/06/2026

Congratulations to Aude Bernheim (@audeber.bsky.social), elected EMBO Member 2026 🎉 Her work on bacterial immunity is reshaping how we understand immune systems across all life forms — from bacteria to humans. @embo.org

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Reposted by Alexandre Hervé

Nature @nature.com · 02/04/2026

Bacteria have been fighting off viruses using a huge arsenal of molecular weaponry that scientists did not know about — until now. Researchers have identified proteins that could lead to virus-fighting drugs and technologies. go.nature.com/4dqQnXI

go.nature.com

‘Treasure trove’ of antiviral proteins could inspire powerful molecular tools

Two research teams mined genomic data from bacteria to create databases containing thousands of antiviral defence proteins that could inspire powerful biotechnologies.

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Reposted by Alexandre Hervé

Aude Bernheim @audeber.bsky.social · 02/04/2026

How diverse is bacterial immunity ? We report in @science.org how language models allowed us to predict 2.4M antiphage proteins spanning >23K novel potential systems. 👏 @emordret.bsky.social, @alexhv.bsky.social & al doi.org/10.1126/scie... Explore them here defensefinder.mdmlab.fr/wiki/refseq_...

science.org

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Reposted by Alexandre Hervé

bioRxivpreprint @biorxivpreprint.bsky.social · 02/04/2025

Structural basis for Lamassu-based antiviral immunity and its evolution from DNA repair machinery www.biorxiv.org/content/10.1101/202…

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Reposted by Alexandre Hervé

Aude Bernheim @audeber.bsky.social · 09/01/2025

What is the diversity of antiphage systems out there ? We used protein and genomic language models (and defense score!) to start bringing some answers: >45 000 protein families. Leb by E. Mordret. www.biorxiv.org/content/10.1... Interactive UMAP to have fun mdmparis.github.io/antiphage-la...

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