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John McGrane

@jmcgrane.bsky.social
152 followers 156 following 149 posts

Clinical oncologist specialising in gynae and urological cancers. Co-host Simply Oncology Podcast. Co-founder MySunrise cancer support app. Husband/dad/lover of sport. Views are my own.

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John McGrane @jmcgrane.bsky.social · 03/10/2026
🚨Simply Oncology Podcast out completing Acute Oncology Services with the superb Dr Caroline Wilson from The Christie Hospital, Manchester🚨 💡Caroline tells how we need to change who manages acute oncology Tox & keep it close to home Enjoy @oncologyforum.bsky.social @icr.ac.uk @ukons.bsky.social
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John McGrane @jmcgrane.bsky.social · 11/09/2026
🚨 Simply Oncology Podcast on the INTENSIFY Trial in met #ProstateCancer out now🚨 🤯 The Doublet or Triplet Q continues in 1st line mHSPC 🤷‍♀️Who should or not have Chemotherapy? We 🗣️ the INTENSIFY trial with Prof Simon Crabb & Dr Sarah Chamberlain funded by @prostatecanceruk.bsky.social Enjoy!
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John McGrane @jmcgrane.bsky.social · 27/07/2026
🚨Simply Oncology Podcast out now🚨 🎙️Back for our 2nd live episode on lifestyle in prostate cancer with the wonderful @alisonbirtle.bsky.social @ethansgrumps.bsky.social @lucygossage.bsky.social The 🏃‍♂️🚲benefits beyond 💊💉drugs to ⬆️ QoL Check it @apccc.bsky.social @prostatecanceruk.bsky.social
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John McGrane @jmcgrane.bsky.social · 03/07/2026
🚨New Simply Oncology Podcast episode on Managing Menopause in Gynae Cancers out today🚨 😥 Menopause in Gynae Cancer patients is a major issue. 🎙️ If you struggle when to advise patients in this area then this is 'Must Listen' episode. @menopausesociety.bsky.social @thercog.bsky.social @bopa.org.uk
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John McGrane @jmcgrane.bsky.social · 28/06/2026
🚨New Simply Oncology Podcast on Platinum Resistant Ovarian Cancer with the amazing Dr Rowan Miller. 🎯Mirvetuxumab & ADCs 🎯Immunotherapy 🎯Relacorilant A revolution is on in a difficult cancer space☀️ Enjoy @targetovarian.bsky.social @thercog.bsky.social @oncologyforum.bsky.social @bopa.org.uk
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John McGrane @jmcgrane.bsky.social · 13/06/2026
🚨New Simply Oncology Podcast out now on the ADePT trial in GBM 🎙️revolutionary ADePT trial in Glioblastoma brain tumours with Dr Faye Robertson. 🎙️ TGX-007 developed with 🧠 🎯 super enhancers 🎯 dual payload 🎯delivery system Hopeful times!! @braintumor.org @braintumourcharity.bsky.social
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John McGrane @jmcgrane.bsky.social · 05/06/2026
🚨Simply Oncology Podcast on the ADePT trial in GBM- Dual Payload Gene Therapy🚨 1st human🙋‍♀️ enrolled! 👏The science & pre human work are incredible. 🎙️ Dr Faye Robertson Edinburgh Cancer Centre talks us through the Trojan Horse 🧠 that is TGX-007. Exciting times👏 @braintumourrsch.bsky.social
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John McGrane @jmcgrane.bsky.social · 08/05/2026
🎙️Simply Oncology Podcast on Adjuvant Therapy in #KidneyCancer out today 🎙️ 🎉Back for part 2 of our Tour of Adjuvant Therapy in Kidney Cancer @will_oncology & @nav_vasudev smash into 🎉 -High risk cases -LITESPARK022 -KIM1 @ikccorg.bsky.social @eururoloncol.bsky.social @natrevcancer.nature.com
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John McGrane @jmcgrane.bsky.social · 01/05/2026
🚨Simply Oncology Podcast on Adjuvant Therapy in #KidneyCancer out today🚨 🎉Joins us as we celebrate 100 episodes in style🎉 🎙️We talk to Dr Will Ince & Dr Naveen Vasudev about the HUGELY EXCITING the adjuvant space in RCC. Enjoy! @euplatinum.bsky.social @ikccorg.bsky.social @eururoloncol.bsky.social
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John McGrane @jmcgrane.bsky.social · 25/04/2026
🚨2 Simply Oncology podcast episodes to talk you through adjuvant and neoadjuvant therapy in Melanoma🚨 🎙️It’s a Melanoma masterclass for Dr Toby Tabot⭐️ 🎙️Adjuvant -Immunotherapy -BRAF 🎙️NADINA trial pre and post IO 🙌🏽 Enjoy! @oncoalert.bsky.social @melanomafocus.bsky.social @skincancerorg.bsky.social
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John McGrane @jmcgrane.bsky.social · 03/04/2026
🚨 New Simply oncology Podcast on Artificial intelligence in Radiotherapy 🚨 AI is the new answer to all things 🧐 🏹 We discuss the international ARCHERY trial using an AI radiotherapy planning tool to streamline RT planning with Prof Ajay Aggarwal🎯 Enjoy @oncoalert.bsky.social @icr.ac.uk
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John McGrane @jmcgrane.bsky.social · 27/03/2026
🎙️Simply Oncology Podcast on PSMA Lutetium in #ProstateCancer out now with the superb Dr Amy Eccles 🎙️ Prostate Cancer Awareness Month we discuss➡️ future of PSMA lutetium & other molecular radiotherapy targets in PCa Enjoy Part 2 of 2 @eururoloncol.bsky.social @oncoalert.bsky.social @uroweb.org
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John McGrane @jmcgrane.bsky.social · 20/03/2026
🚨Simply Oncology Podcast on PSMA lutetium in #ProstateCancer out today🚨 We discuss Targeted Radionuclide Therapy ☢️ Not NHS available yet- we talk to the excellent Dr Amy Eccles and her PSMA lutetium experience. An amazing oversight⭐️ @eururoloncol.bsky.social @imperialcollegeldn.bsky.social
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John McGrane @jmcgrane.bsky.social · 13/03/2026
🎙️ Join us for The Simply Oncology podcast - Late effects after Pelvic Radiotherapy with the excellent Lisa Durrant🎙️ 🎙️ We discuss 🗣️ - hyperbaric oxygen therapy - pelvic floor exercises - sexual function -pain 🚨support after RT = maintain QoL @prda.org.uk @oncodaily.bsky.social
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John McGrane @jmcgrane.bsky.social · 06/03/2026
🚨New Simply Oncology Podcast on #PelvicRadiationDisease with the superb consultant radiographer Lisa Durrant🚨 As we search for cancer cure can we help manage; Bowel Bladder Pain Sexual function Let’s keep QoL with cure🎯 @eururoloncol.bsky.social @oncodaily.bsky.social @lisadurrant.bsky.social
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John McGrane @jmcgrane.bsky.social · 27/02/2026
🎙️Simply Oncology Podcast! We return to discuss #KidneyCancer biomarkers with the wonderful Laurence Albiges⭐️ 🎙️Which biomarker do we think will win traction for mRCC?? 🎙️we return to the microbiome as a biomarker *French summary for some onco -Duolingo🇫🇷 Enjoy!!!
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John McGrane @jmcgrane.bsky.social · 20/02/2026
🚨Simply Oncology Podcast #KidneyCancer What about biomarkers?? The Q we e always ask!! We discuss RCC biomarkers with the fantastic Laurence Albiges 🇫🇷 PDL1 & the CARE1 study KIM1 Sarcomatoid IMDC Wow! @gustaveroussy.fr @eururoloncol.bsky.social @oncologyforum.bsky.social @oncoalert.bsky.social
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John McGrane @jmcgrane.bsky.social · 16/02/2026
@simplyoncology.bsky.social Podcast on advanced #RenalCancer out now! 🎙️The excellent @rickyfrazer1.bsky.social Returns for The Sequel🎯🎯 🎙️non clear cell mRCC 🎙️HIF2a 🎙️Future directions A treat for anyone treating mRCC. Enjoy!! @eururoloncol.bsky.social @euplatinum.bsky.social @uroweb.org
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John McGrane @jmcgrane.bsky.social · 06/02/2026
🚨New Simply Oncology Podcast episode on met #RenalCancer out now🚨 We discuss all things metRCC with @rickyfrazer1.bsky.social from @velindrecc.bsky.social 🎙️TKI vs IO/TKI in Fav risk pts 🎙️IO/IO vs IO/TKI - when to choose 🎙️Would you stop nivo in a responder at 2years? @ikccorg.bsky.social
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John McGrane @jmcgrane.bsky.social · 30/01/2026
🚨 @simplyoncology.bsky.social Podcast out today on Advanced #EndometrialCancer with Dr Gemma @eminowicz.bsky.social 👏 We cover 💊Hormone Therapy 💉ADCs 💊PARP inhibitors 🧨What an exciting time for mEC! @oncologyforum.bsky.social @bjog.bsky.social @myesmo.bsky.social @ucl.ac.uk
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John McGrane @jmcgrane.bsky.social · 23/01/2026
Simply Oncology Podcast on advanced #EndometrialCancer out today🎯 Dr Gemma Eminowicz delivers a superb overview in the molecular era💊 ChemoIO for all or do we sequence? Check it out ⭐️ @eminowicz.bsky.social @natrevcancer.nature.com @bjog.bsky.social @ucl.ac.uk @oncologyforum.bsky.social
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John McGrane @jmcgrane.bsky.social · 17/01/2026
New Simply Oncology podcast with @LizzySmyth1 on #OesophagoGastric cancer. 🎙️Future directions 🎙️Nutrition support 🎙️Mocking me!!! Great finish to our OG overview🎯
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John McGrane @jmcgrane.bsky.social · 09/01/2026
🚨Simply Oncology Podcast out today on metastatic Oesophago-Gastric cancer with the superb Dr @lizzysmyth.bsky.social ⭐️⭐️ We 🗣️ molecular testing and 💊 options in met OG cancer💉 HER2 PDL 1 Claudin 18.2 OG cancer masterclass!! @ouhospitals.bsky.social @oncoalert.bsky.social @oesophagusuk.bsky.social
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John McGrane @jmcgrane.bsky.social · 08/01/2026
🎙️As we look forward to 2026 we would like to take a moment to thank our amazing Simply Oncology Podcast guests from 2025😍 They delivered; - 53 episodes - 1458 minutes of content - listened in 87 countries 🌍 🙏 Thank you to our guests and our listeners ⭐️ More to come in 2026 🧨🧨 @
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John McGrane @jmcgrane.bsky.social · 02/01/2026
The Simply Oncology podcast kicking off 2026 with a bang🎆 We complete our PARPi discussion with Prof Rob Jones⭐️ ARPi-PARPi Which triplet in mHSPC? Rob delivers another masterclass🎯 Link below👇 @apccc.bsky.social @prostatecanceruk.bsky.social @uroweb.org @beatsoncharity.bsky.social
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John McGrane @jmcgrane.bsky.social · 26/12/2025
Xmas is over- eat the 🍗, have another 🍫& treat yourself to ☕️Simply Oncology episode with Prof Rob Jones on PARP inhibitors in #prostatecancer Rob is amazing at setting the scene for PARPi in prostate cancer. @prostatecanceruk.bsky.social @beatsoncharity.bsky.social @eururoloncol.bsky.social
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John McGrane @jmcgrane.bsky.social · 19/12/2025
🎄Christmas Cracker 🎄 We finish our discussion on menopause in #BreastCancer with Rebecca Bowen. Practical tips on Mx🎯 We 🗣️meno.pause that is a resource to guide clinicians⭐️ Ho Ho Hope you enjoy Link below👇 @breastdocuk.bsky.social @breastcancernow.bsky.social @simplyoncology.bsky.social
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John McGrane @jmcgrane.bsky.social · 12/12/2025
🚨New Simply Oncology Podcast episode on the topic of Menopasue side effects in #BreastCancer with the amazing Dr Rebecca Bowen. 🗣️A huge topic and really important for quality of life Link below👇 @breastcancernow.bsky.social @breastcanceruk.bsky.social @breastcancerorg.bsky.social@icr.ac.uk
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John McGrane @jmcgrane.bsky.social · 05/12/2025
🧨New Simply Oncology Episode out today on Sexual Health in Cancer 🚨 We talk to @lorrainegrover.bsky.social - a sexual health nurse specialist in cancer to ⬇️ taboos. 🗣️ erectile dysfn, self-image, confidence from a cancer diagnosis and treatment. This contains adult themes ‼️ @oncoalert.bsky.social
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John McGrane @jmcgrane.bsky.social · 28/11/2025
🎙️Simply oncology episode on metastatic bowel cancer with the amazing Prof Naureen Starling from @royalmarsden.org We complete our molecular walk through 👣 mCRC🎯 🎙️Role of HER2 and ctDNA in mCRC 🎙️MMRd and KRAS agents 🧨 exciting times! @acpgbi.bsky.social @icr.ac.uk @oncoalert.bsky.social
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John McGrane @jmcgrane.bsky.social · 21/11/2025
🚨Friday Feeling with a new Simply Oncology Podcast on metastatic colorectal cancer🚨 ⭐️The wonderful Prof Naureen Starling walks us through the molecular profile of the bowel⭐️ 💊RAS- MMRd- BRAF -HER2 signal a new era in mCRC👏 @oncoalert.bsky.social @icr.ac.uk @acpgbi.bsky.social @royalmarsden.org
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John McGrane @jmcgrane.bsky.social · 14/11/2025
Transgender Awareness Week & we complete our episode with the wonderful Dr Alison Berner⭐️ 🎙️ UCATS & OUTpatients work supporting the transgender community 🎙️Don’t let fear of Saying the wrong thing stop you DOING the right things⭐️ @drallycat.bsky.social @oncodaily.bsky.social @qmbci.bsky.social
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John McGrane @jmcgrane.bsky.social · 07/11/2025
🚨Simply Oncology Podcast out today🚨 🎙️We talk to Dr Alison Berner about work done to support clinicians and patients with cancer care in the transgender community. Amazing to hear the great work done⭐️⭐️ @oncoalert.bsky.social @icr.ac.uk @drallycat.bsky.social 👇link in comments
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John McGrane @jmcgrane.bsky.social · 31/10/2025
🚨New Simply Oncology Podcast👻 We discuss SABR in met #prostatecancer with the superb @alison-tree.bsky.social 🗣️ TRAP study which ⬆️ time to next treatment by 6 months when SABR was used for sites of oligoprogression⚡️ Spookily good 🧟‍♂️ @oncoalert.bsky.social @radiotherapy.bsky.social @icr.ac.uk
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John McGrane @jmcgrane.bsky.social · 24/10/2025
🚨New Simply Oncology episode on using CBM and the gut microbiome to influence IO in #renalcancer Could CBM 588💊 be one of the good 🦠 to unlock our gut biome? Prof Monty Pal is amazing - as always! @oncoalert.bsky.social @kidneycancer.bsky.social @ikccorg.bsky.social @eururoloncol.bsky.social
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John McGrane @jmcgrane.bsky.social · 17/10/2025
New Simply Oncology episode out today🚨 We set the scene for how the Gut Microbiome affects immunotherapy a cancer. We talk to the peerless Prof Monty Pal ⭐️ Monty runs a masterclass on the topic⚡️ Enjoy (esp if travelling to #ESMO25) @oncoalert.bsky.social @myesmo.bsky.social
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John McGrane @jmcgrane.bsky.social · 10/10/2025
Simply Oncology podcast 🔥 Did you know the lifetime risk of prostate cancer in a black man is 1 in 4🤯 ⁉️men in 🏴󠁧󠁢󠁳󠁣󠁴󠁿are ✖️2️⃣ as likely to have advanced prostate cancer than the South of England? Professor Frank Chinegwundoh is on a mission to break down testing barriers🙌🏽 @tackleprostate.bsky.social
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John McGrane @jmcgrane.bsky.social · 03/10/2025
p 71 of the Simply Oncology Podcast out today !!! We are back to finish our journey through Cancer Vaccines 💉🦠with the inspirational @drlennardlee.bsky.social 💫from @ouhospitals.bsky.social Oxford🏨 We celebrate some of the heroes of UK cancer vaccine trials @icr.ac.uk @cancerresearchuk.org
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John McGrane @jmcgrane.bsky.social · 25/09/2025
Simply Oncology Podcast episode 26/09/25 -Cancer Vaccines We talk to @drlennardlee.bsky.social & the mission to take cancer vaccines to the next level💉🦠 🎙️Using AI SUPERCOMPUTERS📟 🎙️⬇️5️⃣0️⃣% relapse Link👇 @myesmo.bsky.social @cancerresearchuk.org @fighting-cancer.bsky.social @oncoalert.bsky.social
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John McGrane @jmcgrane.bsky.social · 19/09/2025
🚨#RectalCancer Simply Oncology podcast today🚨 Richard Adams Returns! 🗣️IO revolution for MSI-H pts 🗣️Future directions 🗣️biggest wish EVER LINK IN COMMENTS 👇 @oncoalert.bsky.social @icr.ac.uk @acpgbi.bsky.social @bowelcanceruk.bsky.social @velindrecc.bsky.social
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John McGrane @jmcgrane.bsky.social · 11/09/2025
New episode of Simply Oncology Podcast on #RectalCancer with Prof Richard Adams out 12/9/25 🎙️Part 1 of 2 of our Tour of Rectal Cancer. 🎙️ Long Course vs Short Course RT 🎙️OPER(A) & RAPIDO ⭐️ @oncoalert.bsky.social @simplyoncology.bsky.social @acpgbi.bsky.social @icr.ac.uk @ascrs.bsky.social
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John McGrane @jmcgrane.bsky.social · 06/09/2025
Episode 66☄️Out Now⚡️ Biliary tract cancer masterclass with Prof John Bridgewater!! Check it out wherever you get your podcasts!! @charityammf.bsky.social @simplyoncology.bsky.social www.buzzsprout.com/2342317/epis...
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John McGrane @jmcgrane.bsky.social · 05/09/2025
Amazing RCC talks at #IUCS25 by the phenomenal Monty Pal & Laurence Albiges 🙌🏽 ⭐️Monty ties together adjuvant &microbiome brilliantly! ⭐️Laurence guided us through RCC biomarkers like KIM-1 and the CARE1 study! What a great meeting Guiseppe & Ravi @eururoloncol.bsky.social @oncodaily.bsky.social
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John McGrane @jmcgrane.bsky.social · 02/09/2025
Simply Oncology Podcast 05.9.25 🎙️We tackle Biliary Tract Cancers with the exceptional Professor John Bridgewater. 🎙️Few people are as knowledgable & linked to a cancer as Prof Bridgewater 🎙️This group of cancers is more common than you think! @charityammf.bsky.social @simplyoncology.bsky.social
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John McGrane @jmcgrane.bsky.social · 28/08/2025
🚨New Simply Oncology Podcast Out 28.8.25 Calling all #ProstateCancer We discuss the challenges of managing patients with rising PSA after prostatectomy. We talk to the excellent @ccparker.bsky.social who has led the RADICALS trial. @royalmarsden.org@prostatecanceruk.bsky.social @icr.ac.uk
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John McGrane @jmcgrane.bsky.social · 22/08/2025
Simply Oncology Podcast Out 22.08.25🚨 We discuss Early Phase Clinical Trials with Dr Natalie Cook from the Christie Early Trials Unit. We learn how molecular profiling is shaping early phase trials and how future trials may be shaped. @simplyoncology.bsky.social @oncocook.bsky.social @icr.ac.uk
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John McGrane @jmcgrane.bsky.social · 20/08/2025
Delighted to hit 10000 downloads for The Simply Oncology Podcast🙌🏽🙌🏽 A massive thank you to all our listeners from around the globe 🌍and our amazing guests👏👏 Listeners from: Australia to America Sweden to South Africa Canada to Cape Verde 🎙️Thank you and keep listening!! @simplyoncology.bsky.social
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John McGrane @jmcgrane.bsky.social · 14/08/2025
🚨New Simply Oncology Episode Out 15.08.2025🚨 Clinical Trials are in our DNA 🧬 in Oncology💉 🎙️We break down the importance of clinical trials with Dr Mohini Varughese who is passionate about clinical trials. @icr.ac.uk @cancerresearchuk.org @cancertrialsie.bsky.social
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John McGrane @jmcgrane.bsky.social · 10/08/2025
@simplyoncology.bsky.social August Menu Specials🥗 Starter - Dr Anthony Cunliffe Language of Oncology Main Course #ClinicalTrials with Dr Mohini Varughese Catch of the day -Early phase trials with @oncocook.bsky.social 🎙️Desert- Post RALP Mx with Prof @ccparker.bsky.social A tasty month!!
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John McGrane @jmcgrane.bsky.social · 07/08/2025
@simplyoncology.bsky.social Episode out tomorrow 2nd part of our talk with Dr Anthony Cunliffe - GP & lead medical advisor @macmillan Communication is key to everything we do We discuss the what & why in onc ✉️and 👂 more about what patients/GP/medical teams need from us @rcgp.bsky.social
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