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John McGrane

@jmcgrane.bsky.social
152 followers 156 following 149 posts

Clinical oncologist specialising in gynae and urological cancers. Co-host Simply Oncology Podcast. Co-founder MySunrise cancer support app. Husband/dad/lover of sport. Views are my own.

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John McGrane @jmcgrane.bsky.social · 03/10/2026
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Episode 122: Acute Oncology services in the future with Dr Caroline Wilson - Simply Oncology
Join us as we complete our discussion on all things Acute Oncology Services with the superb Dr Caroline Wilson PhD FRCP from the The Christie NHS Foundation Trust.🎙️We look at what future directions A...
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John McGrane @jmcgrane.bsky.social · 03/10/2026
🚨Simply Oncology Podcast out completing Acute Oncology Services with the superb Dr Caroline Wilson from The Christie Hospital, Manchester🚨 💡Caroline tells how we need to change who manages acute oncology Tox & keep it close to home Enjoy @oncologyforum.bsky.social @icr.ac.uk @ukons.bsky.social
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John McGrane @jmcgrane.bsky.social · 11/09/2026
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Episode 119: In the Clinic - Discussing the INTENSIFY trial in metastatic prostate cancer with Professor Simon Crabb and Dr Sarah Chamberlain - Simply Oncology
Welcome to the Simply Oncology Podcast. Today we are focusing in on the prostate cancer trial called INTENSIFY. This is a trial where we will look at intensifying metastatic prostate cancer ...
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John McGrane @jmcgrane.bsky.social · 11/09/2026
🚨 Simply Oncology Podcast on the INTENSIFY Trial in met #ProstateCancer out now🚨 🤯 The Doublet or Triplet Q continues in 1st line mHSPC 🤷‍♀️Who should or not have Chemotherapy? We 🗣️ the INTENSIFY trial with Prof Simon Crabb & Dr Sarah Chamberlain funded by @prostatecanceruk.bsky.social Enjoy!
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John McGrane @jmcgrane.bsky.social · 25/08/2026
Thank you so much Tony!
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John McGrane @jmcgrane.bsky.social · 27/07/2026
🚨Simply Oncology Podcast out now🚨 🎙️Back for our 2nd live episode on lifestyle in prostate cancer with the wonderful @alisonbirtle.bsky.social @ethansgrumps.bsky.social @lucygossage.bsky.social The 🏃‍♂️🚲benefits beyond 💊💉drugs to ⬆️ QoL Check it @apccc.bsky.social @prostatecanceruk.bsky.social
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John McGrane @jmcgrane.bsky.social · 03/07/2026
🚨New Simply Oncology Podcast episode on Managing Menopause in Gynae Cancers out today🚨 😥 Menopause in Gynae Cancer patients is a major issue. 🎙️ If you struggle when to advise patients in this area then this is 'Must Listen' episode. @menopausesociety.bsky.social @thercog.bsky.social @bopa.org.uk
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John McGrane @jmcgrane.bsky.social · 28/06/2026
🚨New Simply Oncology Podcast on Platinum Resistant Ovarian Cancer with the amazing Dr Rowan Miller. 🎯Mirvetuxumab & ADCs 🎯Immunotherapy 🎯Relacorilant A revolution is on in a difficult cancer space☀️ Enjoy @targetovarian.bsky.social @thercog.bsky.social @oncologyforum.bsky.social @bopa.org.uk
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John McGrane @jmcgrane.bsky.social · 13/06/2026
🚨New Simply Oncology Podcast out now on the ADePT trial in GBM 🎙️revolutionary ADePT trial in Glioblastoma brain tumours with Dr Faye Robertson. 🎙️ TGX-007 developed with 🧠 🎯 super enhancers 🎯 dual payload 🎯delivery system Hopeful times!! @braintumor.org @braintumourcharity.bsky.social
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John McGrane @jmcgrane.bsky.social · 05/06/2026
🚨Simply Oncology Podcast on the ADePT trial in GBM- Dual Payload Gene Therapy🚨 1st human🙋‍♀️ enrolled! 👏The science & pre human work are incredible. 🎙️ Dr Faye Robertson Edinburgh Cancer Centre talks us through the Trojan Horse 🧠 that is TGX-007. Exciting times👏 @braintumourrsch.bsky.social
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John McGrane @jmcgrane.bsky.social · 08/05/2026
🎙️Simply Oncology Podcast on Adjuvant Therapy in #KidneyCancer out today 🎙️ 🎉Back for part 2 of our Tour of Adjuvant Therapy in Kidney Cancer @will_oncology & @nav_vasudev smash into 🎉 -High risk cases -LITESPARK022 -KIM1 @ikccorg.bsky.social @eururoloncol.bsky.social @natrevcancer.nature.com
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John McGrane @jmcgrane.bsky.social · 01/05/2026
🚨Simply Oncology Podcast on Adjuvant Therapy in #KidneyCancer out today🚨 🎉Joins us as we celebrate 100 episodes in style🎉 🎙️We talk to Dr Will Ince & Dr Naveen Vasudev about the HUGELY EXCITING the adjuvant space in RCC. Enjoy! @euplatinum.bsky.social @ikccorg.bsky.social @eururoloncol.bsky.social
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John McGrane @jmcgrane.bsky.social · 25/04/2026
🚨2 Simply Oncology podcast episodes to talk you through adjuvant and neoadjuvant therapy in Melanoma🚨 🎙️It’s a Melanoma masterclass for Dr Toby Tabot⭐️ 🎙️Adjuvant -Immunotherapy -BRAF 🎙️NADINA trial pre and post IO 🙌🏽 Enjoy! @oncoalert.bsky.social @melanomafocus.bsky.social @skincancerorg.bsky.social
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John McGrane @jmcgrane.bsky.social · 03/04/2026
🚨 New Simply oncology Podcast on Artificial intelligence in Radiotherapy 🚨 AI is the new answer to all things 🧐 🏹 We discuss the international ARCHERY trial using an AI radiotherapy planning tool to streamline RT planning with Prof Ajay Aggarwal🎯 Enjoy @oncoalert.bsky.social @icr.ac.uk
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John McGrane @jmcgrane.bsky.social · 27/03/2026
🎙️Simply Oncology Podcast on PSMA Lutetium in #ProstateCancer out now with the superb Dr Amy Eccles 🎙️ Prostate Cancer Awareness Month we discuss➡️ future of PSMA lutetium & other molecular radiotherapy targets in PCa Enjoy Part 2 of 2 @eururoloncol.bsky.social @oncoalert.bsky.social @uroweb.org
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John McGrane @jmcgrane.bsky.social · 20/03/2026
🚨Simply Oncology Podcast on PSMA lutetium in #ProstateCancer out today🚨 We discuss Targeted Radionuclide Therapy ☢️ Not NHS available yet- we talk to the excellent Dr Amy Eccles and her PSMA lutetium experience. An amazing oversight⭐️ @eururoloncol.bsky.social @imperialcollegeldn.bsky.social
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John McGrane @jmcgrane.bsky.social · 13/03/2026
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Episode 93: Fundamentals - Part 2 of Pelvic Radiation Disease with Lisa Durrant - Simply Oncology
Late effects after pelvic radiotherapy part 2.Join us as we complete our conversation with the wonderful Macmillan Late effects consultant radiographer Lisa Durrant.Last week we discussed late bladder...
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John McGrane @jmcgrane.bsky.social · 13/03/2026
🎙️ Join us for The Simply Oncology podcast - Late effects after Pelvic Radiotherapy with the excellent Lisa Durrant🎙️ 🎙️ We discuss 🗣️ - hyperbaric oxygen therapy - pelvic floor exercises - sexual function -pain 🚨support after RT = maintain QoL @prda.org.uk @oncodaily.bsky.social
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John McGrane @jmcgrane.bsky.social · 06/03/2026
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Episode 92: Fundamentals - Discussing Pelvic Radiation Disease with Lisa Durrant - Simply Oncology
Join us as we discuss the impact of Pelvic Radiation Disease & the late effects of radiotherapy in the pelvis.We re always trying to get he best result for our patients and to cure cancer but we n...
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John McGrane @jmcgrane.bsky.social · 06/03/2026
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Episode 92: Fundamentals - Discussing Pelvic Radiation Disease with Lisa Durrant - Simply Oncology
Join us as we discuss the impact of Pelvic Radiation Disease & the late effects of radiotherapy in the pelvis.We re always trying to get he best result for our patients and to cure cancer but we n...
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John McGrane @jmcgrane.bsky.social · 06/03/2026
🚨New Simply Oncology Podcast on #PelvicRadiationDisease with the superb consultant radiographer Lisa Durrant🚨 As we search for cancer cure can we help manage; Bowel Bladder Pain Sexual function Let’s keep QoL with cure🎯 @eururoloncol.bsky.social @oncodaily.bsky.social @lisadurrant.bsky.social
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John McGrane @jmcgrane.bsky.social · 27/02/2026
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Episode 91: In the Clinic - Biomarkers in advanced Kidney Cancer with Professor Laurence Albiges (part 2) - Simply Oncology
Join us as return to our excellent conversation on biomarkers in kidney cancer with the wonderful Professor Laurence Albiges from Paris.🎙️We finish our overview of Biomarkers in metastatic Kidney Canc...
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John McGrane @jmcgrane.bsky.social · 27/02/2026
🎙️Simply Oncology Podcast! We return to discuss #KidneyCancer biomarkers with the wonderful Laurence Albiges⭐️ 🎙️Which biomarker do we think will win traction for mRCC?? 🎙️we return to the microbiome as a biomarker *French summary for some onco -Duolingo🇫🇷 Enjoy!!!
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John McGrane @jmcgrane.bsky.social · 20/02/2026
🚨Simply Oncology Podcast #KidneyCancer What about biomarkers?? The Q we e always ask!! We discuss RCC biomarkers with the fantastic Laurence Albiges 🇫🇷 PDL1 & the CARE1 study KIM1 Sarcomatoid IMDC Wow! @gustaveroussy.fr @eururoloncol.bsky.social @oncologyforum.bsky.social @oncoalert.bsky.social
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John McGrane @jmcgrane.bsky.social · 16/02/2026
@simplyoncology.bsky.social Podcast on advanced #RenalCancer out now! 🎙️The excellent @rickyfrazer1.bsky.social Returns for The Sequel🎯🎯 🎙️non clear cell mRCC 🎙️HIF2a 🎙️Future directions A treat for anyone treating mRCC. Enjoy!! @eururoloncol.bsky.social @euplatinum.bsky.social @uroweb.org
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John McGrane @jmcgrane.bsky.social · 06/02/2026
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Episode 88: In the clinic - Metastatic Renal Cancer with Professor Ricky Frazer (part 1/2) - Simply Oncology
Join us is as we celebrate Kidney Cancer week with a Masterclass walk through metastatic Renal Cancer with Professor Ricky Frazer from Velindre Cancer Centre.Ricky is a co-host of the hugely successfu...
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John McGrane @jmcgrane.bsky.social · 06/02/2026
🚨New Simply Oncology Podcast episode on met #RenalCancer out now🚨 We discuss all things metRCC with @rickyfrazer1.bsky.social from @velindrecc.bsky.social 🎙️TKI vs IO/TKI in Fav risk pts 🎙️IO/IO vs IO/TKI - when to choose 🎙️Would you stop nivo in a responder at 2years? @ikccorg.bsky.social
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John McGrane @jmcgrane.bsky.social · 30/01/2026
🚨 @simplyoncology.bsky.social Podcast out today on Advanced #EndometrialCancer with Dr Gemma @eminowicz.bsky.social 👏 We cover 💊Hormone Therapy 💉ADCs 💊PARP inhibitors 🧨What an exciting time for mEC! @oncologyforum.bsky.social @bjog.bsky.social @myesmo.bsky.social @ucl.ac.uk
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John McGrane @jmcgrane.bsky.social · 23/01/2026
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Episode 86: The Metastatic Endometrial Cancer landscape with Dr Gemma Eminowicz (1/2) - Simply Oncology
Dr Gemma Eminowicz returns for 2026!!Join us as we discuss the metastatic endometrial cancer landscape with Simply Oncology 'friend of the show' Dr Gemma Eminowicz from University College Hospital Lon...
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John McGrane @jmcgrane.bsky.social · 23/01/2026
Simply Oncology Podcast on advanced #EndometrialCancer out today🎯 Dr Gemma Eminowicz delivers a superb overview in the molecular era💊 ChemoIO for all or do we sequence? Check it out ⭐️ @eminowicz.bsky.social @natrevcancer.nature.com @bjog.bsky.social @ucl.ac.uk @oncologyforum.bsky.social
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John McGrane @jmcgrane.bsky.social · 17/01/2026
New Simply Oncology podcast with @LizzySmyth1 on #OesophagoGastric cancer. 🎙️Future directions 🎙️Nutrition support 🎙️Mocking me!!! Great finish to our OG overview🎯
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John McGrane @jmcgrane.bsky.social · 09/01/2026
🚨Simply Oncology Podcast out today on metastatic Oesophago-Gastric cancer with the superb Dr @lizzysmyth.bsky.social ⭐️⭐️ We 🗣️ molecular testing and 💊 options in met OG cancer💉 HER2 PDL 1 Claudin 18.2 OG cancer masterclass!! @ouhospitals.bsky.social @oncoalert.bsky.social @oesophagusuk.bsky.social
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John McGrane @jmcgrane.bsky.social · 08/01/2026
🎙️As we look forward to 2026 we would like to take a moment to thank our amazing Simply Oncology Podcast guests from 2025😍 They delivered; - 53 episodes - 1458 minutes of content - listened in 87 countries 🌍 🙏 Thank you to our guests and our listeners ⭐️ More to come in 2026 🧨🧨 @
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John McGrane @jmcgrane.bsky.social · 02/01/2026
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Episode 83: In the Clinic - Part 2 of PARPi in prostate cancer with Professor Rob Jones - Simply Oncology
Happy New Year!!!WE return in 2026 to complete our overview of PARPi in prostate cancer with the peerless Professor Rob Jones.
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John McGrane @jmcgrane.bsky.social · 02/01/2026
The Simply Oncology podcast kicking off 2026 with a bang🎆 We complete our PARPi discussion with Prof Rob Jones⭐️ ARPi-PARPi Which triplet in mHSPC? Rob delivers another masterclass🎯 Link below👇 @apccc.bsky.social @prostatecanceruk.bsky.social @uroweb.org @beatsoncharity.bsky.social
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John McGrane @jmcgrane.bsky.social · 26/12/2025
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Episode 82: in the Clinic - PARP inhibitors in metastatic Prostate Cancer with Professor Rob Jones - Simply Oncology
Join us as we unwind in the Christmas Holiday period with a masterful overview of PARP inhibitors in metastatic prostate cancer with Professor Rob Jones.Rob is an old friend of the show and is amazing...
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John McGrane @jmcgrane.bsky.social · 26/12/2025
Xmas is over- eat the 🍗, have another 🍫& treat yourself to ☕️Simply Oncology episode with Prof Rob Jones on PARP inhibitors in #prostatecancer Rob is amazing at setting the scene for PARPi in prostate cancer. @prostatecanceruk.bsky.social @beatsoncharity.bsky.social @eururoloncol.bsky.social
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John McGrane @jmcgrane.bsky.social · 19/12/2025
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Episode 81: Part 2 Management of menopause and breast cancer with Dr Rebecca Bowen - Simply Oncology
Welcome back!In part 1 we discussed the major effects of menopause and how these can be worsened by hormonal medications given to treat breast cancer and the impact these can have on patients completi...
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John McGrane @jmcgrane.bsky.social · 19/12/2025
🎄Christmas Cracker 🎄 We finish our discussion on menopause in #BreastCancer with Rebecca Bowen. Practical tips on Mx🎯 We 🗣️meno.pause that is a resource to guide clinicians⭐️ Ho Ho Hope you enjoy Link below👇 @breastdocuk.bsky.social @breastcancernow.bsky.social @simplyoncology.bsky.social
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John McGrane @jmcgrane.bsky.social · 12/12/2025
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simplyoncology.buzzsprout.com
Episode 80: Part 1 Menopause management and breast cancer with Dr Rebecca Bowen - Simply Oncology
When is it safe to giving HRT in women who are being treated or have previously been diagnosed with breast cancer?Will the use of vaginal oestrogens affect breast cancer outcomes?What is the trade off...
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John McGrane @jmcgrane.bsky.social · 12/12/2025
🚨New Simply Oncology Podcast episode on the topic of Menopasue side effects in #BreastCancer with the amazing Dr Rebecca Bowen. 🗣️A huge topic and really important for quality of life Link below👇 @breastcancernow.bsky.social @breastcanceruk.bsky.social @breastcancerorg.bsky.social@icr.ac.uk
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John McGrane @jmcgrane.bsky.social · 06/12/2025
That would be great
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John McGrane @jmcgrane.bsky.social · 05/12/2025
Not specifically Dan but we plan to revisit the topic as we think it is hugely underserved
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John McGrane @jmcgrane.bsky.social · 05/12/2025
🧨New Simply Oncology Episode out today on Sexual Health in Cancer 🚨 We talk to @lorrainegrover.bsky.social - a sexual health nurse specialist in cancer to ⬇️ taboos. 🗣️ erectile dysfn, self-image, confidence from a cancer diagnosis and treatment. This contains adult themes ‼️ @oncoalert.bsky.social
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John McGrane @jmcgrane.bsky.social · 28/11/2025
🎙️Simply oncology episode on metastatic bowel cancer with the amazing Prof Naureen Starling from @royalmarsden.org We complete our molecular walk through 👣 mCRC🎯 🎙️Role of HER2 and ctDNA in mCRC 🎙️MMRd and KRAS agents 🧨 exciting times! @acpgbi.bsky.social @icr.ac.uk @oncoalert.bsky.social
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John McGrane @jmcgrane.bsky.social · 21/11/2025
🚨Friday Feeling with a new Simply Oncology Podcast on metastatic colorectal cancer🚨 ⭐️The wonderful Prof Naureen Starling walks us through the molecular profile of the bowel⭐️ 💊RAS- MMRd- BRAF -HER2 signal a new era in mCRC👏 @oncoalert.bsky.social @icr.ac.uk @acpgbi.bsky.social @royalmarsden.org
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Reposted by John McGrane
All You Need is Lungs @allyouneedislungs.bsky.social · 16/11/2025
Every day, 130 people in the UK are diagnosed with #lungcancer. That’s one person every 11 minutes. Lung cancer can affect anyone & spotting it early can make a real difference. Be alert to symptoms that don’t go away, like: a cough, breathlessness, fatigue, pain in chest/shoulder/back. #LCSM
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John McGrane @jmcgrane.bsky.social · 14/11/2025
Transgender Awareness Week & we complete our episode with the wonderful Dr Alison Berner⭐️ 🎙️ UCATS & OUTpatients work supporting the transgender community 🎙️Don’t let fear of Saying the wrong thing stop you DOING the right things⭐️ @drallycat.bsky.social @oncodaily.bsky.social @qmbci.bsky.social
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John McGrane @jmcgrane.bsky.social · 07/11/2025
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Episode 75: Discussing Cancer Care in the Transgender Community with Dr Alison Berner - Simply Oncology
As we approach transgender awareness week we discuss cancer care in the transgender community with the exceptional Dr Alison Berner.1 in 40 people aged under 30 identify as transgender in recent censu...
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John McGrane @jmcgrane.bsky.social · 07/11/2025
🚨Simply Oncology Podcast out today🚨 🎙️We talk to Dr Alison Berner about work done to support clinicians and patients with cancer care in the transgender community. Amazing to hear the great work done⭐️⭐️ @oncoalert.bsky.social @icr.ac.uk @drallycat.bsky.social 👇link in comments
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