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John McGrane

@jmcgrane.bsky.social
150 followers 156 following 147 posts

Clinical oncologist specialising in gynae and urological cancers. Co-host Simply Oncology Podcast. Co-founder MySunrise cancer support app. Husband/dad/lover of sport. Views are my own.

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John McGrane @jmcgrane.bsky.social · 11/09/2026
🚨 Simply Oncology Podcast on the INTENSIFY Trial in met #ProstateCancer out now🚨 🤯 The Doublet or Triplet Q continues in 1st line mHSPC 🤷‍♀️Who should or not have Chemotherapy? We 🗣️ the INTENSIFY trial with Prof Simon Crabb & Dr Sarah Chamberlain funded by @prostatecanceruk.bsky.social Enjoy!
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John McGrane @jmcgrane.bsky.social · 27/07/2026
🚨Simply Oncology Podcast out now🚨 🎙️Back for our 2nd live episode on lifestyle in prostate cancer with the wonderful @alisonbirtle.bsky.social @ethansgrumps.bsky.social @lucygossage.bsky.social The 🏃‍♂️🚲benefits beyond 💊💉drugs to ⬆️ QoL Check it @apccc.bsky.social @prostatecanceruk.bsky.social
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John McGrane @jmcgrane.bsky.social · 03/07/2026
🚨New Simply Oncology Podcast episode on Managing Menopause in Gynae Cancers out today🚨 😥 Menopause in Gynae Cancer patients is a major issue. 🎙️ If you struggle when to advise patients in this area then this is 'Must Listen' episode. @menopausesociety.bsky.social @thercog.bsky.social @bopa.org.uk
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John McGrane @jmcgrane.bsky.social · 28/06/2026
🚨New Simply Oncology Podcast on Platinum Resistant Ovarian Cancer with the amazing Dr Rowan Miller. 🎯Mirvetuxumab & ADCs 🎯Immunotherapy 🎯Relacorilant A revolution is on in a difficult cancer space☀️ Enjoy @targetovarian.bsky.social @thercog.bsky.social @oncologyforum.bsky.social @bopa.org.uk
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John McGrane @jmcgrane.bsky.social · 13/06/2026
🚨New Simply Oncology Podcast out now on the ADePT trial in GBM 🎙️revolutionary ADePT trial in Glioblastoma brain tumours with Dr Faye Robertson. 🎙️ TGX-007 developed with 🧠 🎯 super enhancers 🎯 dual payload 🎯delivery system Hopeful times!! @braintumor.org @braintumourcharity.bsky.social
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John McGrane @jmcgrane.bsky.social · 05/06/2026
🚨Simply Oncology Podcast on the ADePT trial in GBM- Dual Payload Gene Therapy🚨 1st human🙋‍♀️ enrolled! 👏The science & pre human work are incredible. 🎙️ Dr Faye Robertson Edinburgh Cancer Centre talks us through the Trojan Horse 🧠 that is TGX-007. Exciting times👏 @braintumourrsch.bsky.social
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John McGrane @jmcgrane.bsky.social · 08/05/2026
🎙️Simply Oncology Podcast on Adjuvant Therapy in #KidneyCancer out today 🎙️ 🎉Back for part 2 of our Tour of Adjuvant Therapy in Kidney Cancer @will_oncology & @nav_vasudev smash into 🎉 -High risk cases -LITESPARK022 -KIM1 @ikccorg.bsky.social @eururoloncol.bsky.social @natrevcancer.nature.com
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John McGrane @jmcgrane.bsky.social · 01/05/2026
🚨Simply Oncology Podcast on Adjuvant Therapy in #KidneyCancer out today🚨 🎉Joins us as we celebrate 100 episodes in style🎉 🎙️We talk to Dr Will Ince & Dr Naveen Vasudev about the HUGELY EXCITING the adjuvant space in RCC. Enjoy! @euplatinum.bsky.social @ikccorg.bsky.social @eururoloncol.bsky.social
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John McGrane @jmcgrane.bsky.social · 25/04/2026
🚨2 Simply Oncology podcast episodes to talk you through adjuvant and neoadjuvant therapy in Melanoma🚨 🎙️It’s a Melanoma masterclass for Dr Toby Tabot⭐️ 🎙️Adjuvant -Immunotherapy -BRAF 🎙️NADINA trial pre and post IO 🙌🏽 Enjoy! @oncoalert.bsky.social @melanomafocus.bsky.social @skincancerorg.bsky.social
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John McGrane @jmcgrane.bsky.social · 03/04/2026
🚨 New Simply oncology Podcast on Artificial intelligence in Radiotherapy 🚨 AI is the new answer to all things 🧐 🏹 We discuss the international ARCHERY trial using an AI radiotherapy planning tool to streamline RT planning with Prof Ajay Aggarwal🎯 Enjoy @oncoalert.bsky.social @icr.ac.uk
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John McGrane @jmcgrane.bsky.social · 27/03/2026
🎙️Simply Oncology Podcast on PSMA Lutetium in #ProstateCancer out now with the superb Dr Amy Eccles 🎙️ Prostate Cancer Awareness Month we discuss➡️ future of PSMA lutetium & other molecular radiotherapy targets in PCa Enjoy Part 2 of 2 @eururoloncol.bsky.social @oncoalert.bsky.social @uroweb.org
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John McGrane @jmcgrane.bsky.social · 20/03/2026
🚨Simply Oncology Podcast on PSMA lutetium in #ProstateCancer out today🚨 We discuss Targeted Radionuclide Therapy ☢️ Not NHS available yet- we talk to the excellent Dr Amy Eccles and her PSMA lutetium experience. An amazing oversight⭐️ @eururoloncol.bsky.social @imperialcollegeldn.bsky.social
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John McGrane @jmcgrane.bsky.social · 13/03/2026
🎙️ Join us for The Simply Oncology podcast - Late effects after Pelvic Radiotherapy with the excellent Lisa Durrant🎙️ 🎙️ We discuss 🗣️ - hyperbaric oxygen therapy - pelvic floor exercises - sexual function -pain 🚨support after RT = maintain QoL @prda.org.uk @oncodaily.bsky.social
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John McGrane @jmcgrane.bsky.social · 06/03/2026
🚨New Simply Oncology Podcast on #PelvicRadiationDisease with the superb consultant radiographer Lisa Durrant🚨 As we search for cancer cure can we help manage; Bowel Bladder Pain Sexual function Let’s keep QoL with cure🎯 @eururoloncol.bsky.social @oncodaily.bsky.social @lisadurrant.bsky.social
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John McGrane @jmcgrane.bsky.social · 27/02/2026
🎙️Simply Oncology Podcast! We return to discuss #KidneyCancer biomarkers with the wonderful Laurence Albiges⭐️ 🎙️Which biomarker do we think will win traction for mRCC?? 🎙️we return to the microbiome as a biomarker *French summary for some onco -Duolingo🇫🇷 Enjoy!!!
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John McGrane @jmcgrane.bsky.social · 20/02/2026
🚨Simply Oncology Podcast #KidneyCancer What about biomarkers?? The Q we e always ask!! We discuss RCC biomarkers with the fantastic Laurence Albiges 🇫🇷 PDL1 & the CARE1 study KIM1 Sarcomatoid IMDC Wow! @gustaveroussy.fr @eururoloncol.bsky.social @oncologyforum.bsky.social @oncoalert.bsky.social
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John McGrane @jmcgrane.bsky.social · 16/02/2026
@simplyoncology.bsky.social Podcast on advanced #RenalCancer out now! 🎙️The excellent @rickyfrazer1.bsky.social Returns for The Sequel🎯🎯 🎙️non clear cell mRCC 🎙️HIF2a 🎙️Future directions A treat for anyone treating mRCC. Enjoy!! @eururoloncol.bsky.social @euplatinum.bsky.social @uroweb.org
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John McGrane @jmcgrane.bsky.social · 06/02/2026
🚨New Simply Oncology Podcast episode on met #RenalCancer out now🚨 We discuss all things metRCC with @rickyfrazer1.bsky.social from @velindrecc.bsky.social 🎙️TKI vs IO/TKI in Fav risk pts 🎙️IO/IO vs IO/TKI - when to choose 🎙️Would you stop nivo in a responder at 2years? @ikccorg.bsky.social
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John McGrane @jmcgrane.bsky.social · 30/01/2026
🚨 @simplyoncology.bsky.social Podcast out today on Advanced #EndometrialCancer with Dr Gemma @eminowicz.bsky.social 👏 We cover 💊Hormone Therapy 💉ADCs 💊PARP inhibitors 🧨What an exciting time for mEC! @oncologyforum.bsky.social @bjog.bsky.social @myesmo.bsky.social @ucl.ac.uk
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John McGrane @jmcgrane.bsky.social · 23/01/2026
Simply Oncology Podcast on advanced #EndometrialCancer out today🎯 Dr Gemma Eminowicz delivers a superb overview in the molecular era💊 ChemoIO for all or do we sequence? Check it out ⭐️ @eminowicz.bsky.social @natrevcancer.nature.com @bjog.bsky.social @ucl.ac.uk @oncologyforum.bsky.social
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John McGrane @jmcgrane.bsky.social · 17/01/2026
New Simply Oncology podcast with @LizzySmyth1 on #OesophagoGastric cancer. 🎙️Future directions 🎙️Nutrition support 🎙️Mocking me!!! Great finish to our OG overview🎯
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John McGrane @jmcgrane.bsky.social · 09/01/2026
🚨Simply Oncology Podcast out today on metastatic Oesophago-Gastric cancer with the superb Dr @lizzysmyth.bsky.social ⭐️⭐️ We 🗣️ molecular testing and 💊 options in met OG cancer💉 HER2 PDL 1 Claudin 18.2 OG cancer masterclass!! @ouhospitals.bsky.social @oncoalert.bsky.social @oesophagusuk.bsky.social
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John McGrane @jmcgrane.bsky.social · 08/01/2026
🎙️As we look forward to 2026 we would like to take a moment to thank our amazing Simply Oncology Podcast guests from 2025😍 They delivered; - 53 episodes - 1458 minutes of content - listened in 87 countries 🌍 🙏 Thank you to our guests and our listeners ⭐️ More to come in 2026 🧨🧨 @
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John McGrane @jmcgrane.bsky.social · 02/01/2026
The Simply Oncology podcast kicking off 2026 with a bang🎆 We complete our PARPi discussion with Prof Rob Jones⭐️ ARPi-PARPi Which triplet in mHSPC? Rob delivers another masterclass🎯 Link below👇 @apccc.bsky.social @prostatecanceruk.bsky.social @uroweb.org @beatsoncharity.bsky.social
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John McGrane @jmcgrane.bsky.social · 26/12/2025
Xmas is over- eat the 🍗, have another 🍫& treat yourself to ☕️Simply Oncology episode with Prof Rob Jones on PARP inhibitors in #prostatecancer Rob is amazing at setting the scene for PARPi in prostate cancer. @prostatecanceruk.bsky.social @beatsoncharity.bsky.social @eururoloncol.bsky.social
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John McGrane @jmcgrane.bsky.social · 19/12/2025
🎄Christmas Cracker 🎄 We finish our discussion on menopause in #BreastCancer with Rebecca Bowen. Practical tips on Mx🎯 We 🗣️meno.pause that is a resource to guide clinicians⭐️ Ho Ho Hope you enjoy Link below👇 @breastdocuk.bsky.social @breastcancernow.bsky.social @simplyoncology.bsky.social
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John McGrane @jmcgrane.bsky.social · 12/12/2025
🚨New Simply Oncology Podcast episode on the topic of Menopasue side effects in #BreastCancer with the amazing Dr Rebecca Bowen. 🗣️A huge topic and really important for quality of life Link below👇 @breastcancernow.bsky.social @breastcanceruk.bsky.social @breastcancerorg.bsky.social@icr.ac.uk
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John McGrane @jmcgrane.bsky.social · 05/12/2025
🧨New Simply Oncology Episode out today on Sexual Health in Cancer 🚨 We talk to @lorrainegrover.bsky.social - a sexual health nurse specialist in cancer to ⬇️ taboos. 🗣️ erectile dysfn, self-image, confidence from a cancer diagnosis and treatment. This contains adult themes ‼️ @oncoalert.bsky.social
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John McGrane @jmcgrane.bsky.social · 28/11/2025
🎙️Simply oncology episode on metastatic bowel cancer with the amazing Prof Naureen Starling from @royalmarsden.org We complete our molecular walk through 👣 mCRC🎯 🎙️Role of HER2 and ctDNA in mCRC 🎙️MMRd and KRAS agents 🧨 exciting times! @acpgbi.bsky.social @icr.ac.uk @oncoalert.bsky.social
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John McGrane @jmcgrane.bsky.social · 21/11/2025
🚨Friday Feeling with a new Simply Oncology Podcast on metastatic colorectal cancer🚨 ⭐️The wonderful Prof Naureen Starling walks us through the molecular profile of the bowel⭐️ 💊RAS- MMRd- BRAF -HER2 signal a new era in mCRC👏 @oncoalert.bsky.social @icr.ac.uk @acpgbi.bsky.social @royalmarsden.org
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All You Need is Lungs @allyouneedislungs.bsky.social · 16/11/2025
Every day, 130 people in the UK are diagnosed with #lungcancer. That’s one person every 11 minutes. Lung cancer can affect anyone & spotting it early can make a real difference. Be alert to symptoms that don’t go away, like: a cough, breathlessness, fatigue, pain in chest/shoulder/back. #LCSM
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John McGrane @jmcgrane.bsky.social · 14/11/2025
Transgender Awareness Week & we complete our episode with the wonderful Dr Alison Berner⭐️ 🎙️ UCATS & OUTpatients work supporting the transgender community 🎙️Don’t let fear of Saying the wrong thing stop you DOING the right things⭐️ @drallycat.bsky.social @oncodaily.bsky.social @qmbci.bsky.social
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John McGrane @jmcgrane.bsky.social · 07/11/2025
🚨Simply Oncology Podcast out today🚨 🎙️We talk to Dr Alison Berner about work done to support clinicians and patients with cancer care in the transgender community. Amazing to hear the great work done⭐️⭐️ @oncoalert.bsky.social @icr.ac.uk @drallycat.bsky.social 👇link in comments
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The OncoAlert Network 🚨 @oncoalert.bsky.social · 04/11/2025
Starting THIS FRIDAY November 7, 2025 DIRECT from NASHVILLE🇺🇸 #UromigosLIVE WE ARE THERE 🚨Stay Tuned for Coverage!! Presenting Our Ambassadors & OncoAlert 🚨GU Faculty
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John McGrane @jmcgrane.bsky.social · 31/10/2025
🚨New Simply Oncology Podcast👻 We discuss SABR in met #prostatecancer with the superb @alison-tree.bsky.social 🗣️ TRAP study which ⬆️ time to next treatment by 6 months when SABR was used for sites of oligoprogression⚡️ Spookily good 🧟‍♂️ @oncoalert.bsky.social @radiotherapy.bsky.social @icr.ac.uk
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Lesley Smith @lesleysmith.bsky.social · 24/10/2025
Great to see a PROM study on #QoL following chemoradiation for cervical ca. However I take issue with “returned to baseline” at 9 mth, implying that symptoms will stay at baseline indefinitely - not true, late effects can arise yrs later #PelvicRadiationDisease www.news-medical.net/news/2025102...
news-medical.net
Cervical cancer patients treated with radiation and chemotherapy report greater short-term decline in quality of life
A new study co-led by investigators at the UCLA Health Jonsson Comprehensive Cancer Center found that women with early-stage cervical cancer who received radiation plus chemotherapy reported a greater...
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John McGrane @jmcgrane.bsky.social · 24/10/2025
🚨New Simply Oncology episode on using CBM and the gut microbiome to influence IO in #renalcancer Could CBM 588💊 be one of the good 🦠 to unlock our gut biome? Prof Monty Pal is amazing - as always! @oncoalert.bsky.social @kidneycancer.bsky.social @ikccorg.bsky.social @eururoloncol.bsky.social
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John McGrane @jmcgrane.bsky.social · 17/10/2025
New Simply Oncology episode out today🚨 We set the scene for how the Gut Microbiome affects immunotherapy a cancer. We talk to the peerless Prof Monty Pal ⭐️ Monty runs a masterclass on the topic⚡️ Enjoy (esp if travelling to #ESMO25) @oncoalert.bsky.social @myesmo.bsky.social
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John McGrane @jmcgrane.bsky.social · 10/10/2025
Simply Oncology podcast 🔥 Did you know the lifetime risk of prostate cancer in a black man is 1 in 4🤯 ⁉️men in 🏴󠁧󠁢󠁳󠁣󠁴󠁿are ✖️2️⃣ as likely to have advanced prostate cancer than the South of England? Professor Frank Chinegwundoh is on a mission to break down testing barriers🙌🏽 @tackleprostate.bsky.social
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John McGrane @jmcgrane.bsky.social · 03/10/2025
🚨Kidney Cancer UK patient survey is now live🚨 It is SO important for patients to have their say🗣️ If you are a #kidneycancer patient help set out what your goals for treatment & you⭐️ Click on link below👇 @kidneycancer.bsky.social @baunnurses.bsky.social kcuk.questionpro.com/a/TakeSurvey...
kcuk.questionpro.com
Kidney Cancer UK Patient Survey 2025
Kidney Cancer UK Patient Survey 2025
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John McGrane @jmcgrane.bsky.social · 03/10/2025
p 71 of the Simply Oncology Podcast out today !!! We are back to finish our journey through Cancer Vaccines 💉🦠with the inspirational @drlennardlee.bsky.social 💫from @ouhospitals.bsky.social Oxford🏨 We celebrate some of the heroes of UK cancer vaccine trials @icr.ac.uk @cancerresearchuk.org
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John McGrane @jmcgrane.bsky.social · 25/09/2025
Simply Oncology Podcast episode 26/09/25 -Cancer Vaccines We talk to @drlennardlee.bsky.social & the mission to take cancer vaccines to the next level💉🦠 🎙️Using AI SUPERCOMPUTERS📟 🎙️⬇️5️⃣0️⃣% relapse Link👇 @myesmo.bsky.social @cancerresearchuk.org @fighting-cancer.bsky.social @oncoalert.bsky.social
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John McGrane @jmcgrane.bsky.social · 19/09/2025
🚨#RectalCancer Simply Oncology podcast today🚨 Richard Adams Returns! 🗣️IO revolution for MSI-H pts 🗣️Future directions 🗣️biggest wish EVER LINK IN COMMENTS 👇 @oncoalert.bsky.social @icr.ac.uk @acpgbi.bsky.social @bowelcanceruk.bsky.social @velindrecc.bsky.social
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John McGrane @jmcgrane.bsky.social · 12/09/2025
💥Out Today!! A Rectal cancer discussion with the incomparable Prof Richard Adams! If you have an interest in #RectalCancer this is a MUST LISTEN! Check it out 👇 @icorc.bsky.social @acpgbi.bsky.social @oncoalert.bsky.social @icr.ac.uk @oncologyforum.bsky.social @ www.buzzsprout.com/2342317/epis...
buzzsprout.com
Episode 67: In the Clinic - Advances in Rectal Cancer (Part 1) with Professor Richard Adams - Simply Oncology
In this episode we venture in to a new tumour site:  Colorectal Cancer.We are joined by internationally renowned oncologist Professor Richard Adams from Velindre Cancer Centre.In Part 1 we dive i...
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John McGrane @jmcgrane.bsky.social · 11/09/2025
New episode of Simply Oncology Podcast on #RectalCancer with Prof Richard Adams out 12/9/25 🎙️Part 1 of 2 of our Tour of Rectal Cancer. 🎙️ Long Course vs Short Course RT 🎙️OPER(A) & RAPIDO ⭐️ @oncoalert.bsky.social @simplyoncology.bsky.social @acpgbi.bsky.social @icr.ac.uk @ascrs.bsky.social
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John McGrane @jmcgrane.bsky.social · 06/09/2025
Episode 66☄️Out Now⚡️ Biliary tract cancer masterclass with Prof John Bridgewater!! Check it out wherever you get your podcasts!! @charityammf.bsky.social @simplyoncology.bsky.social www.buzzsprout.com/2342317/epis...
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John McGrane @jmcgrane.bsky.social · 05/09/2025
Amazing RCC talks at #IUCS25 by the phenomenal Monty Pal & Laurence Albiges 🙌🏽 ⭐️Monty ties together adjuvant &microbiome brilliantly! ⭐️Laurence guided us through RCC biomarkers like KIM-1 and the CARE1 study! What a great meeting Guiseppe & Ravi @eururoloncol.bsky.social @oncodaily.bsky.social
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Craig Gedye @craiggedye.bsky.social · 04/09/2025
Fantastic to have this critical advice for older people with cancer - thank you @crisbergerot.bsky.social @bogda-koczwara.bsky.social and team
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John McGrane @jmcgrane.bsky.social · 05/09/2025
🚨Simply Oncology Podcast - new episode out today!! Everything you need to know about Biliary Tract Cancers with the amazing Prof John Bridgewater👇 🎙️New tartgeted treatments 🎙️Immunotherapy www.buzzsprout.com/2342317/epis... @charityammf.bsky.social @oncoalert.bsky.social @oncodaily.bsky.social
buzzsprout.com
Episode 66: Biliary Tract Cancer Masterclass with Professor John Bridgewater - Simply Oncology
Biliary Tract Cancers - Cholangiocarcinomas and Gallbladder cancers are often seen as rare and aggressive cancers.🎙️We tackle Biliary Tract Cancers with the exceptional Professor John Bridgewater.🎙️Fe...
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John McGrane @jmcgrane.bsky.social · 02/09/2025
Simply Oncology Podcast 05.9.25 🎙️We tackle Biliary Tract Cancers with the exceptional Professor John Bridgewater. 🎙️Few people are as knowledgable & linked to a cancer as Prof Bridgewater 🎙️This group of cancers is more common than you think! @charityammf.bsky.social @simplyoncology.bsky.social
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