The ISMO After-ASCO 2026 Virtual Updates Meeting took place online on Wednesday, 24 June 2026. Organised by ISMO in partnership with Cancer Trials Ireland, this annual virtual meeting shared key highlights and takeaways from ASCO 2026 for the oncology community in Ireland. The programme included expert updates across skin, lung, genitourinary, gastrointestinal, breast and CNS oncology, alongside AI at ASCO and patient-partnered research and PPI. Thank you to all speakers, chairs and attendees who contributed to the meeting. Programme areas included: • Skin oncology • Lung oncology • Genitourinary oncology • Gastrointestinal oncology • Breast oncology • CNS oncology • Patient-partnered research and PPI • AI at ASCO Organised by ISMO in partnership with Cancer Trials Ireland. For more information about Cancer Trials Ireland, visit: www.cancertrials.ie #ASCO2026 #Oncology #CancerTrials #CancerResearch #PatientInvolvement

What does it take to open and run a cancer clinical trial? The Life of a Cancer Trial follows the Isa-RVD cancer trial for newly diagnosed multiple myeloma, showing the people, processes and purpose behind cancer trials in Ireland. Through Jed’s experience as a patient on the trial, alongside insights from Prof Peter O’Gorman, the Clinical Trials team at the Mater Hospital and Cancer Trials Ireland colleagues, the film explores the work involved in bringing a trial from idea to patient recruitment, treatment, monitoring, data collection and sharing results. The film highlights the collaboration involved in cancer trials: patients and families, investigators, research nurses, hospital site teams, data teams, trial managers, monitors, funders, industry partners and international collaborators all working together to answer important questions and improve treatment options for patients. Cancer Trials Ireland is the national organisation dedicated to cancer trials in Ireland. We work with hospital sites, investigators, patients, funders and international partners to make cancer trials available to patients in Ireland. Find out more: www.cancertrials.ie Chapters: 00:00 Jed’s diagnosis and joining the Isa-RVD trial 00:43 Developing the trial 02:10 Patient safety, funding and oversight 02:42 Collaboration across the trial team 03:14 Opening the trial at site 03:44 Recruitment, consent and screening 04:34 Supporting patients on a trial 05:15 The role of the nursing team 06:31 Why trial data matters 07:27 Jed’s experience on the trial 08:07 Sharing results and contributing to global research 09:11 Hope, family and patient impact #CancerTrialsIreland #CancerTrials #ClinicalTrials #CancerResearch #MultipleMyeloma

DE-ESCALATE is part of a series of clinical trials funded by the Horizon Europe programme as part of the EU Mission on Cancer. The twelve clinical trials, led by multistakeholder and multidisciplinary consortiums, form together the European Cancer Cluster. This video gives an introduction to the project's aims and objectives. DE-ESCALATE Project: https://deescalate-horizon.eu/ EU Cancer Mission: https://research-and-innovation.ec.europa.eu/funding/funding-opportunities/funding-programmes-and-open-calls/horizon-europe/eu-missions-horizon-europe/eu-mission-cancer_en https://diagnosticsandtreatmentcluster.eu/ #deescalate_horizon #EUCancerMission #cancerresearch #HorizonEurope #prostatecancerresearch #clinicaltrials #evidencebasedmedicine #IADT © The DE-ESCALATE Consortium 2023-2028. This project has received funding from the European Union’s HORIZON-MISS-CANCER-2022-01 under grant agreement Nº (101103655). Views and opinions expressed are however those of the authors only and do not necessarily reflect those of the European Union. Neither the European Union nor the granting authority can be held responsible for them.