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Jose Jimenez

@jjimenez.bsky.social
1.2K followers 885 following 159 posts

Associate Professor in Synthetic Biology at Imperial College London #synbio and evolution for health, the environment and the circular economy josejimenezlab.com

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Jose Jimenez @jjimenez.bsky.social · 23/09/2026
Big news! Congratulations to Said Muñoz-Montero on passing his PhD viva with flying colours. Really proud of Said who investigated population dynamics of AMR bacteria in fluctuating environments. Well done Said!!🍾🎉🎉🥳
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Jose Jimenez @jjimenez.bsky.social · 15/09/2026
We are recruiting!! We are looking for an expert in the metabolic engineering of non model microorganisms to join our team working on plastic waste upcycling. For details please check the link below. www.imperial.ac.uk/jobs/search-...
imperial.ac.uk
Description
Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...
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Everyone’s Favourite Jim @jimmeruk.bsky.social · 13/09/2026
Cunts have just stolen my bike from the garage and fucked my garage door. If anyone sees this around Croydon, let me know.
Norco Threshold A1 with orange Brooks bartape and saddle.
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Julian Parkhill @julianparkhill.bsky.social · 08/09/2026
Chair in Bacteriology in Cambridge Department of Medicine. A great opportunity. Please circulate. www.cam.ac.uk/jobs/researc...
cam.ac.uk
Research Professor in the field of Bacteriology
Strengthening Cambridge's leadership in bacteriology research Bacterial infection and antimicrobial resistance remain among the most pressing global health challenges of our time. At Cambridge, the De...
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Lorraine Reese @lorraine-reese.bsky.social · 01/09/2026
Early booking and abstract deadline for Synthetic Biology UK 2026 is TOMORROW! Sessions will cover protein and enzyme design, genome-scale rewriting, next-generation nucleic acid technologies and the engineering of genetic circuits and cellular control systems #synbio 🧪 bit.ly/Synthetic_Biology_2026
Biochemical Society Scientific Meeting: Synthetic Biology UK. Hampshire, UK, 2-3 November 2026. Abstract submissions now open. Earlybird deadline 2 September 2026. Includes image of delegates during a poster session at a previous Synthetic Biology meeting, and Biochemical Society and event logos
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Jose Jimenez @jjimenez.bsky.social · 19/08/2026
The headline of this article in Positive News picking up on our recent paper with SIRIM and Polymateria is both hilarious and precise. I couldn't have put it better myself: "Stubborn plastics were turned into bug food" www.positive.news/society/good...
positive.news
What went right this week: the good news that matters
Plummeting deforestation in Brazil’s Amazon, hurricane-predicting sharks and a courtroom reckoning on the cards for tech giants, plus more
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Jose Jimenez @jjimenez.bsky.social · 17/08/2026
And more news from around the world, this time the Daily Observer from Bangladesh picks up the work with Polymateria's degradable PE and PP! observerbd.com/news/587721
observerbd.com
Study finds common plastics can biodegrade within two years
Common plastics that can persist in the environment for hundreds of years can be fully broken down by naturally occurring
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Jose Jimenez @jjimenez.bsky.social · 16/08/2026
Really nice to see some coverage of our recent paper with Polymateria and SIRIM in Malaysian's news outlets! www.nst.com.my/news/nation/...
nst.com.my
Study finds common plastics can biodegrade within two years | New Straits Times
KUALA LUMPUR: Common plastics that can persist in the environment for hundreds of years can be fully broken down by naturally occurring microbes within two years, according to a study by Malaysia's St...
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Jose Jimenez @jjimenez.bsky.social · 11/08/2026
Delighted to see a new paper out from the lab on plastic biodegradation. This time we have joined forces with Polymateria Ltd to demonstrate for the first time the complete biodegradation of polyethylene and polypropylene thanks to their proprietary technology www.nature.com/articles/s41...
nature.com
Masterbatch-enabled acceleration of polyolefin biodegradation under open air terrestrial environmental conditions - npj Materials Degradation
npj Materials Degradation - Masterbatch-enabled acceleration of polyolefin biodegradation under open air terrestrial environmental conditions
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Jose Jimenez @jjimenez.bsky.social · 12/07/2026
Mood in Brixton. Everyone waiting for the return of Ulysses Bellingham
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Jose Jimenez @jjimenez.bsky.social · 01/07/2026
Absolutely over the moon to see our work of whole-cell PET plastic bioremediation with engineered bacteria published in its final form!!! authors.elsevier.com/sd/article/S... This is a World-Cup-worth 🏆 effort of an amazing team led by Alice Banks, Umar Abdulmutalib and Brooke Wain.
authors.elsevier.com
Engineering environmental bacteria for whole-cell PET hydrolysis and assimilation
Poly(ethylene terephthalate) (PET) is one of the most widely used plastics in food and textile applications, yet post-consumer PET waste persists and …
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Jose Jimenez @jjimenez.bsky.social · 09/06/2026
New paper out!! Really enjoyed working with Juhyun Kim from Kyungpook National University thinking about how microbial cell factories, minicells and microbial communities can be harnessed for safe and precise food production. www.sciencedirect.com/science/arti...
sciencedirect.com
Safe and resource-aware microbial design for food production
Precision fermentation is redefining microbial food manufacturing by enabling programmable biosynthesis of nutrients and functional ingredients. Despi…
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Matt Jago @mattjago.bsky.social · 04/06/2026
Our work characterizing how mutational bias is influenced by the local sequence context beyond trinucleotides is out now @pnas.org! We also showed which motifs are most prone to mutations caused by strand misalignment, revealing several new hotspots! 🧬 www.pnas.org/doi/10.1073/...
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Jose Jimenez @jjimenez.bsky.social · 14/05/2026
Really exciting to see this paper out! This is a massive effort from clinicians, bioinformaticians and microbiologists investigating links between pancreatic and bile microbiota in healthy individuals and cancer patients. journals.lww.com/internationa...
journals.lww.com
The bile microbiome is a surrogate for the intratumoral... : International Journal of Surgery
pared to benign and malignant pancreatico–biliary disease, as well as correlate our findings with the pancreatic intratumoral and neighboring adjacent tissue (NAT) microbiome. Methods: Prospective ...
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Freya Harrison @friendlymicrobe.bsky.social · 20/04/2026
My super department @warwicklifesci.bsky.social is hiring 6 assistant profs in the wake of recent retirements. We're looking for people in microbiology/infection, cellular disease / immunity; environmental biology; and plant/crop science. #MicroSky warwick-careers.tal.net/vx/lang-en-G...
warwick-careers.tal.net
Assistant Professor x6 (111522-0426) - University of Warwick
Title: Assistant Professor x6 (111522-0426). Application Deadline: . Position Type: Permanent
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Raphael Laurenceau @raphael-microb.bsky.social · 16/04/2026
🔈Paper out! We turned the most fascinating phage host-switch mechanism, diversity-generating retroelements, into a programmable mutagenesis tool, DGRec. You can perform targeted hypermutation of any 50-200bp sequence directly in vivo in E. coli www.nature.com/articles/s41...
nature.com
Diversity-generating retroelements for programmable targeted hypermutagenesis - Nature Biotechnology
Diversity-generating retroelements are engineered for directed evolution in E.coli.
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Richard Sever @richardsever.bsky.social · 11/04/2026
Nobel Laureate Jack Szostak “This country has given me endless opportunities…: The America we inhabit today bears almost no resemblance to the country I chose all those years ago” newsletter.ofthebrave.org/p/im-a-nobel...
newsletter.ofthebrave.org
I’m a Nobel Prize-winning immigrant. I can no longer recognize this country.
Attacks on science and immigrants are destroying America.
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Claudia Contini @continiclau.bsky.social · 02/04/2026
🚨 Please share this fully-funded #PhD #opportunity within your network!👇 👇 Only two weeks are left to apply! @imperiallifesci.bsky.social @imperialsci.bsky.social @imperial-edu.bsky.social @imperialcollegeldn.bsky.social
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Jose Jimenez @jjimenez.bsky.social · 17/03/2026
Great work from Jo Sadler's group!!
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Jose Jimenez @jjimenez.bsky.social · 09/03/2026
As scientists, asking ourselves if our direction of travel is the right one is the responsible thing to do. This is why I'm really pleased to share this article summarising our reflections on the current state of biobased approaches to manage #plastic waste. www.nature.com/articles/s41...
nature.com
Reflections on bio-based PET and plastic waste management: a responsible research and innovation approach - Nature Communications
Bio-based approaches to plastic degradation have been an intense area of research in recent years, and although they show great promise, they also raise societal, ethical and regulatory questions. Her...
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Tobias Warnecke @tobiaswarnecke.bsky.social · 05/03/2026
Pls re-post: My department @oxfordbiochemistry.bsky.social are recruiting for several new faculty positions (links below). Broad search in molecular biology/biochemistry, across prokaryotes and eukaryotes. Interested in understanding life at the molecular level, this job might be for you! 1/n
my.corehr.com
Job Details
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Jose Jimenez @jjimenez.bsky.social · 03/03/2026
Fully endorse this view at least in prokaryotes. Someone once told me that "cells are bags of ribosomes making more ribosomes". It may be worth considering that at some point in multicellular evolution (of eukaryotes?) this was abandoned by a more organism-centric strategy
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Jose Jimenez @jjimenez.bsky.social · 26/02/2026
🚨🚨🚨LAST CHANCE!! - Closing tomorrow!!! 🚨🚨🚨
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Andy Radford @andyradford.bsky.social · 23/02/2026
🚨JOB alert🚨 We have three (yes, THREE) 🌟lectureships🌟 advertised in the School of Biological Sciences, University of Bristol. Broad remit, including #AnimalBehaviour & #GlobalChangeBiology ⏱️Deadline: 8th March 2026 🙏Please circulate widely 😊Come join us! Full #job details: tinyurl.com/y3us95rc
bristol.ac.uk
Details | Working at Bristol | University of Bristol
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Jose Jimenez @jjimenez.bsky.social · 20/02/2026
One week left to apply to this PhD studentship!! Do not miss this opportunity! 💷 Fully paid tuition and stipend for 3.5 years 📅 Deadline 27th February 🇬🇧 Home fees (UK national / settled status) 🧫 ⚗️ ⚛️ Interdisciplinary team
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LondonSynbioNetwork @londonsynbio.bsky.social · 16/02/2026
Join us Feb. 26 at Imperial! 🧬 PromoterAtlas: decoding regulatory sequences across Gammaproteobacteria using a transformer model Lucas Coppens (Biofoundry) 🌾 Resurrecting plant defence mechanisms to avoid crop pathogens Imogen Binnian (Resurrect Bio) tinyurl.com/2d52z38h
tinyurl.com
London SynBio Network 14
London SynBio afterwork talks and networking event on Thursday 26th of January
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Edoardo Gianni @edogia.bsky.social · 13/02/2026
How could a simple self-replicating system emerge at the origins of life? RNA polymerase ribozymes can replicate RNA, but existing ones are so large that their self-replication seems impossible. Could they be smaller? Excited to share our latest work in @science.org on a new small polymerase. 1/n
science.org
A small polymerase ribozyme that can synthesize itself and its complementary strand
The emergence of a chemical system capable of self-replication and evolution is a critical event in the origin of life. RNA polymerase ribozymes can replicate RNA, but their large size and structural ...
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Jose Jimenez @jjimenez.bsky.social · 11/02/2026
Join us in our crusade to make materials sustainable! We are recruiting a PhD student (home fees) to work on an exciting project to decarbonise the nylon industry and create new biodegradable materials. Info on how to apply here: www.imperial.ac.uk/school-of-co... (deadline 27th of February!)
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Jose Jimenez @jjimenez.bsky.social · 11/02/2026
Reposting this paper now with a working link! 😅 www.sciencedirect.com/science/arti...
sciencedirect.com
Engineering whole-cell catalysts to use plastic waste as a feedstock
The extensive production, durability, and waste mismanagement of plastic polymers have led to a highly concerning environmental problem. Recycling met…
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Victor de Lorenzo (CNB, Madrid) @vdlorenzo.bsky.social · 06/02/2026
Feel like doing a SynBio PhD in Spain? Check this offer, many fellowships available 👉🏻 lifehub.csic.es/synbio-cofund/
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Jose Jimenez @jjimenez.bsky.social · 23/01/2026
"Are you not worried that engineered microbes can be released into the environment and eat all the plastic?" The answer is not really. Pleased to share our latest piece addressing this question by evaluating the current status of whole-cell plastic degradation: www.sciencedirect.com/science/arti...
sciencedirect.com
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Scott Berry @scottbscience.bsky.social · 15/01/2026
What happens when you suddenly remove half of an essential enzyme from cells? 🤔 We watched in real-time as cells deploy multiple backup strategies to buffer against changes in RNA Pol II abundance. Our lab's new preprint 👇 bit.ly/4pyPgax
bit.ly
Hierarchical buffering of cellular RNA polymerase II pools maintains transcriptional homeostasis
RNA polymerase II (Pol II) abundance and transcriptional output are coordinated across diverse conditions to maintain mRNA homeostasis. To determine whether Pol II acts as a limiting factor for transc...
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Centro de Investigaciones Biológicas Margarita Salas (CSIC) @cib-csic.bsky.social · 08/01/2026
#CIBpapers Researchers at the @cib-csic.bsky.social present a new bacterium capable of transforming plastic waste into high-value bioproducts More info 🔗https://cib.csic.es/news/research/researchers-cib-margarita-salas-present-new-bacterium-capable-transforming-plastic
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Jose Jimenez @jjimenez.bsky.social · 01/01/2026
New year resolution: develop the strength and technique to do ONE bloody muscle-up. Not a lot to ask. That at the back is the Bay of Cadiz. Not a bad place to start 2026. Happy New Year!!
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Jose Jimenez @jjimenez.bsky.social · 26/12/2025
Really happy to see this paper out. It looks like Santa had us on the nice list!! Congrats to all authors, it's been such a joy to be involved!
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Michael Brockhurst @brockhurstlab.bsky.social · 20/12/2025
Manchester Institute of Biotechnology is looking for a new Professor. There are a few priority areas including microbial engineering (broadly defined, from pathways to cells to microbiomes). Closing 12 Jan. Join us in the best city in the UK 😜 www.jobs.manchester.ac.uk/Job/JobDetai...
jobs.manchester.ac.uk
Professorial Appointment within the Manchester Institute of Biotechnology:Manchester Institute of Biotechnology
Applications are invited for a professorial appointment to be based in the Manchester Institute of Biotechnology (MIB) at the University of Manchester (UoM). The successful candidate will join a dynamic research environment at an exciting time and will help shape the institute research priorities and national/international profile. We are open to high quality applications from across the broad engineering biology and biotechnology landscape. Specific areas of interest include but are not limited to chemical biology of disease related proteins, natural product biosynthesis and enzyme discovery; structural biology and mechanistic enzymology; and microbial engineering.
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Francesca Ceroni @ceronifranci.bsky.social · 17/12/2025
So you think your mammalian plasmids have nothing to fear from cloning and propagation in E.coli? Quantitative profiling of millions of nucleotides by Tom Copeman will prove you wrong! Supervised with the amazing @proftomellis.bsky.social and AZ, now on BioRxiv: doi.org/10.64898/202...
doi.org
Quantitative profiling of millions of nucleotides reveals sequence-encoded interactions that govern plasmid propagation
Plasmids are central to modern biotechnology, especially therapeutic development, yet their propagation in Escherichia coli remains difficult to predict. Although expression-induced burden is well und...
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Ed Cunningham-Oakes @edcoakes.bsky.social · 16/12/2025
- Using novel genomic tools to understand the evolution of Acinetobacter baumannii pathogenicity in clinical environments Supervisors: David Grainger, Katie Hopkins, Jessica Blair, Willem van Schaik www.findaphd.com/phds/project... (4/7)
findaphd.com
Using novel genomic tools to understand the evolution of Acinetobacter baumannii pathogenicity in clinical environments at University of Birmingham on FindAPhD.com
PhD Project - Using novel genomic tools to understand the evolution of Acinetobacter baumannii pathogenicity in clinical environments at University of Birmingham, listed on FindAPhD.com
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Jose Jimenez @jjimenez.bsky.social · 16/12/2025
As the year comes close to an end, just wanted to thank all team members for making my everyday better. Really proud of this talented and selfless group of scientists!!
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Andy Edwards @bugsinblood.bsky.social · 03/12/2025
We're advertising for a bacteriology technician and a post-doc to work on AI-guided antibiotic development as part of a large multidisciplinary Fleming Initiative project: www.imperial.ac.uk/jobs/search-... www.imperial.ac.uk/jobs/search-...
imperial.ac.uk
Description
Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...
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Kazuaki Amikura @amikura.bsky.social · 24/11/2025
Our paper is out! Analysis of 30K+ genomes revealed that CPR bacteria assemble their ribosomes in unconventional ways, and that these assembly processes appear to have co-evolved with ribosome structure. doi.org/10.1093/molb... #Ribosome #Evolution #Patescibacteria #MBE
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Jose Jimenez @jjimenez.bsky.social · 14/11/2025
Just found this definition in the gov.uk webpage that thought might be useful for some. Btw, someone between 14 and 18 years old is sometimes called a Young Person, but is still legally a child.
Official government definition of children in the UK
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Jose Jimenez @jjimenez.bsky.social · 31/10/2025
The scariest thing I have seen this Halloween
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The Wallace Lab @swallacelab.bsky.social · 29/10/2025
The Wallace Lab is expanding in 2026, with five new Postdoctoral Research Associate positions now open. If you're passionate about engineering biology for sustainability, we'd love to hear from you! 🧬 ♻️ Deadline: 12th November 2025, details below ⬇️
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Alex Fedorec @ajfedorec.bsky.social · 20/10/2025
1 week left to apply for a postdoctoral position in my group to lead the experimental component of a 5 year BBSRC project on synthetic microbial communities www.ucl.ac.uk/work-at-ucl/...
ucl.ac.uk
UCL – University College London
UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).
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LondonSynbioNetwork @londonsynbio.bsky.social · 16/10/2025
Oct. 23, 6pm at UCL 🥳! Excited for: 🧬 Dirk Benzinger (Briscoe Lab) Dissecting and engineering cellular signal processing with synthetic biology and optogenetics 🌍 Brooke Wain (Jimenez Lab) Biocatalytic recycling of plastic: industrial viability and limitations events.humanitix.com/london-synbi...
events.humanitix.com
London SynBio Network 11
London SynBio afterwork talks and networking event on Thursday 23rd of September
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Jose Jimenez @jjimenez.bsky.social · 11/10/2025
This is how Castilla La Mancha will conquer the world: blending tradition and empathy. I'd recommend all world leaders to complete a couple of grape harvests (vendimia) to develop thoughtful leadership. Great mix of cardio and strength exercise too! www.theguardian.com/world/2025/o...
theguardian.com
‘It’s a question of humanity’: how a small Spanish town made headlines over its immigration stance
Mayor explains why Villamalea unanimously backed call to regularise undocumented migrants – across party lines
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Jose Jimenez @jjimenez.bsky.social · 08/10/2025
New preprint this time through a fantastic collaboration with @jorgebarriuso.bsky.social and team. We have discovered the genetic basis behind the remarkable ability of Pseudomonas putida JM37 to use the PET #plastic monomer ethylene glycol as a growth substrate! www.biorxiv.org/content/10.1...
biorxiv.org
Pseudomonas putida JM37 as a novel bacterial chassis for ethylene glycol upcycling
Ethylene glycol (EG), one of the main monomers of polyethylene terephthalate (PET), is an attractive target for microbial upcycling. Despite this interest, there is a limited number of described organ...
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Ákos T Kovács @evolvedbiofilm.bsky.social · 07/10/2025
Metabolic interplay drives population cycles in a cross-feeding microbial community @natcomms.nature.com from @oventurelli2.bsky.social www.nature.com/articles/s41...
nature.com
Metabolic interplay drives population cycles in a cross-feeding microbial community - Nature Communications
Here the authors leverage a crossfeeding, engineered microbial community to demonstrate that strain abundance cycles are robust across environmental conditions. They pair this with a nonlinear dynamic model to elucidate population cycles.
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Tung Le @tunglejic.bsky.social · 03/10/2025
Independent research fellowships leading to tenured positions at the John Innes Centre. Repost = nice. Thank you very much!!!
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