Sign in

Kazuaki Amikura

@amikura.bsky.social
42 followers 43 following 8 posts

Researcher @Yale -> 🚀 -> @RIKEN, Japan #Ribosome #Synbio sites.google.com/view/amikura

PostsRepliesMedia
Reposted by Kazuaki Amikura
Filippo Caschera @stjle.bsky.social · 22/04/2026
Alteromonas macleodii ribosome enables consecutive incorporation of bulky D-amino acids into peptides academic.oup.com/nar/article/...
academic.oup.com
The Alteromonas macleodii ribosome enables consecutive incorporation of bulky D-amino acids into peptides
Abstract. Genetic code reprogramming allows for ribosomal incorporation of exotic amino acids, such as d-α- and d-β-amino acids, into peptides. However, th
011
Kazuaki Amikura @amikura.bsky.social · 20/02/2026
Bacterial GTPases act as successive placeholders to mediate ribosome assembly and its coupling to translation initiation www.biorxiv.org/content/10.6...
biorxiv.org
030
Kazuaki Amikura @amikura.bsky.social · 02/02/2026
Pleased to share our new paper. Group I introns uniquely accumulate in Patescibacteria (formerly CPR bacteria), are inserted at an unusual tRNA position (35/36), and belong to a distinct intron class. Congratulations, Yuna! mSystems journals.asm.org/doi/10.1128/...
journals.asm.org
Group I introns in tRNA genes of Patescibacteria | mSystems
Introns were traditionally thought to be rare in bacteria, yet their occurrence and diversity may have been underestimated. Here, we present the first comprehensive overview of group I and group II in...
030
Reposted by Kazuaki Amikura
Jamie Cate @jhdcate.bsky.social · 20/01/2026
"Use it or lose it." This is great advice for exercise, but when cells need to slow down or go dormant, they need to store ribosomes to recover growth in the future. They use hibernation factors to do this. Here is our latest story on how archaea hibernate ribosomes (1/7): doi.org/10.64898/202...
doi.org
14217
Reposted by Kazuaki Amikura
bioRxiv Synthetic Biology @biorxiv-synthbio.bsky.social · 06/01/2026
Enhanced tRNA array method version 2 for simultaneous in vitro synthesis of 21 tRNAs www.biorxiv.org/content/10.64898/20…
001
Kazuaki Amikura @amikura.bsky.social · 08/12/2025
Impact of acetate on CO2 fixation pathways in thermophilic and hydrogenotrophic bacteria url: academic.oup.com/ismecommun/a...
academic.oup.com
Impact of acetate on CO2 fixation pathways in thermophilic and hydrogenotrophic bacteria
Abstract. The bacterial-type Wood-Ljungdahl (WL) pathway and reductive tricarboxylic acid (rTCA) cycle are the dominant chemolithotrophic CO2 fixation path
000
Reposted by Kazuaki Amikura
Frances Yap @ribo1214.bsky.social · 26/11/2025
#Ribosome #hibernation 🧪
022
Kazuaki Amikura @amikura.bsky.social · 24/11/2025
Our paper is out! Analysis of 30K+ genomes revealed that CPR bacteria assemble their ribosomes in unconventional ways, and that these assembly processes appear to have co-evolved with ribosome structure. doi.org/10.1093/molb... #Ribosome #Evolution #Patescibacteria #MBE
1128
Reposted by Kazuaki Amikura
bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 05/11/2025
The evolution lifecycle of ribosome hibernation factors www.biorxiv.org/content/10.1101/202…
042
Kazuaki Amikura @amikura.bsky.social · 04/07/2025
Our new preprint is now available! We found a new Group I intron insertion site in tRNA genes of Patescibacteria. These tRNAs were missed by standard tRNA annotation tools. #microbiology #tRNA #Patescibacteria
010
Reposted by Kazuaki Amikura
Laura Eme @lauraeme.bsky.social · 17/06/2025
🎉 Now out “Phylogenomic analyses indicate the archaeal superphylum DPANN originated from free‑living euryarchaeal‑like ancestors” www.nature.com/articles/s41...
nature.com
Phylogenomic analyses indicate the archaeal superphylum DPANN originated from free-living euryarchaeal-like ancestors - Nature Microbiology
Phylogenetic reconstructions with conserved protein markers from the 11 known DPANN phyla reveal their monophyletic placement within the Euryarchaeota.
28937
Reposted by Kazuaki Amikura
Sergey Melnikov @sergeymelnikov.bsky.social · 19/06/2025
Here, we show that bacterial ribosomes—often viewed as conserved drug targets—actually vary across species due to extensive sequence variation in their drug-binding residues. In some cases, this divergence may lead to intrinsic drug resistance in certain bacterial clades: doi.org/10.1016/j.ce...
03120
Reposted by Kazuaki Amikura
Maria Polychronidou @mpolychronidou.bsky.social · 18/06/2025
"With an apparent inability to live outside its host, and with a genome less than half the size of the previously smallest archaeon genome, Sukunaarchaeum is unlike any other archaeon known." ➡️ www.science.org/content/arti... #MicroSky #Archaea
science.org
Microbe with bizarrely tiny genome may be evolving into a virus
With DNA focused almost entirely on replication, newly discovered organism blurs the line between cells and viruses
2105
Reposted by Kazuaki Amikura
Sergey Melnikov @sergeymelnikov.bsky.social · 20/03/2025
Here we unexpectedly find that the ribosomal protein S20/L26—identified at the dawn of ribosome research but later deemed a biochemical artifact—is indeed a genuine component of the large ribosomal subunit. More on this ribosome content variation is here: www.nature.com/articles/s41...
nature.com
Structurally heterogeneous ribosomes cooperate in protein synthesis in bacterial cells - Nature Communications
Cells can simultaneously produce structurally dissimilar ribosomes, suggesting functional specialization of distinct ribosome populations. Here, the authors show that distinct ribosomes cooperate rath...
14623
Kazuaki Amikura @amikura.bsky.social · 11/12/2024
The binding of RbgA to a critical 50S assembly intermediate facilitates YphC function in bacterial ribosomal assembly academic.oup.com/nar/advance-...
academic.oup.com
The binding of RbgA to a critical 50S assembly intermediate facilitates YphC function in bacterial ribosomal assembly
Abstract. The intricate process of 50S ribosomal subunit assembly in Bacillus subtilis involves multiple parallel pathways converging into a crucial interm
022
Reposted by Kazuaki Amikura
Cameron Thrash @jcamthrash.bsky.social · 02/12/2024
Evolutionary flexibility of ribosome biogenesis in bacteria www.biorxiv.org/content/10.1... #jcampubs
032
Kazuaki Amikura @amikura.bsky.social · 08/12/2024
Our preprint is now available!🎊🚀 Ribosome biogenesis in CPR bacteria was unexpectedly flexible, challenging traditional view of this essential process in evolution. #Ribosome #CPR #Evolution
061