The Cellanome R3200 Instrument combines longitudinal live-cell imaging with same-cell transcriptomics to link morphology, function, interactions, and molecular state over time. The complete platform i...

The transition from seed to seedling requires chromatin reprogramming. By studying the histone variant H2B.8, the authors show that it organizes silent chromatin in dry seeds and reveal that water upt...

Helitrons are a recently identified category of transposons. This study reveals that heat stress combined with reduced DNA methylation can mobilize a Helitron family in wheat. Its mobilization is gene...

The soybean RdDM pathway suppresses premature immune gene activation by maintaining TE-proximal defense genes methylated and repressed, preventing autoimmu

DNA methylation loss at transposable elements (TEs) can affect neighboring genes and be epigenetically inherited in plants, yet the determinants and significance of this additional system of inheritan...

The complexity of varied modifications of chromatin composition is integrated in archetypal combinations called chromatin states that predict the local potential for transcription. The degree of conse...

Single-cell long-read RNA sequencing enables the high-fidelity mapping of single-cell expression data from highly sequence-similar transposable elements to unique genomic loci by correcting errors fro...

An opportunity for an academic position as a Research Fellow (Postdoctoral) is available, as advertised on jobs.ac.uk. Apply now and explore other academic job openings.

Gene expression and complex phenotypes are determined by the activity of cis-regulatory elements. However, an understanding of how extant genetic variants affect cis regulation remains limited. Here, ...

Global N4 cytosine methylation in Marchantia polymorpha sperm regulates gene expression and promotes sperm fertility.

Varying gene dosage through mutating DNA methyltransferase 1-1 (MET1-1 ) in polyploid wheat generates quantitative changes to CG methylation without the le

How plants first invented seeds is a longstanding unresolved evolutionary question. Seed-bearing plants arose from within seedless vascular plants, with ferns as their closest relatives, but how the s...