Summary: This study presents a live-imaging platform for tracking individual plant protoplasts in culture, enabling analysis of cellular processes, signaling dynamics and developmental transitions.

A mechanistic basis for how the hormone salicylic acid promotes transcriptional activation during plant immune responses is described.

The specification of embryonic stem cells capable of self-renewing and differentiation into virtually any cell type, is one of the most consequential events in the development of a multicellular organ...

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

In nature, plants experience complex combinations of environmental stresses. Prior studies using Arabidopsis thaliana show that transcriptional responses to combinatorial stress are unique and cannot ...

Rate limitation in translational elongation causes ribosomes to pause as they decode an open reading frame (ORF). The triggers and outcomes of these events are poorly understood in plants. Here, we si...

Genotype-by-environment interactions (GxE), or differences in how genotypes perform across varying environments, are a pervasive source of phenotypic variation and underlie differences in local adapta...

Super-enhancers have been proposed to cluster in the nucleus when compared to other genomic elements. Le et al. found that super-enhancer clustering was rare and driven by non-specific interactions. P...

Root anatomical barriers, including the suberized and lignified walls of the endodermis and exodermis, and cortical aerenchyma, regulate water and nutrient transport, gas exchange, and rhizosphere int...

Transcription factor nanoclusters balance the DNA binding trade-off between weakly binding oligomers and nonspecific condensates.

Peng et al. review mechanisms driving lamina expansion, including gene expression, auxin-mediated proliferation, and microtubule-directed growth, linking disrupted coordination to morphological defect...

snRNA-seq reveals shoot stem cell heterogeneity and traces their differentiation into primary stem cell types.

Helitrons are a recently identified category of transposons. This study reveals that heat stress combined with reduced DNA methylation can mobilize a Helitron family in wheat. Its mobilization is gene...

Gene expression is a fundamentally stochastic process, with randomness in transcription and translation leading to cell-to-cell variations in mRNA and protein levels. This variation appears in organis...

Abstract. The integration of artificial intelligence (AI) into computational biology is changing biological research, particularly in agriculture, where la

A four-dimensional spatial gene expression transcriptome atlas of Hordeum vulgare (barley) grain development and germination revealed tissue, cell, cluster

Nature Reviews Genetics, Published online: 09 March 2026; doi:10.1038/s41576-026-00939-1In this Perspective, Maizels and Briscoe discuss the limitations of current models of gene regulatory networks and outline solutions to harness data abundance without compromising explanatory power.