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Philippa Borrill

@philippaborrill.bsky.social
1K followers 337 following 31 posts

Wheat geneticist and group leader at John Innes Centre. Interested in #micronutrients, #senescence, #polyploidy and #genomics. She/her. borrilllab.com

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Reposted by Philippa Borrill
charpentiermyriam.bsky.social @charpentiermyriam.bsky.social · 11/02/2026
My lab at the JIC is recruiting 3 PDRA: 🔹 Bioinformatics / AI 🔹 Molecular Biology / Genetics 🔹 Proteomics Programme funded by the Novo Nordisk Foundation. 📅 Closing date: 27 February Apply via JIC website: www.jic.ac.uk/vacancies/ Please share with outstanding candidates. 🙏
jic.ac.uk
Postdoctoral Researcher (Charpentier Group) | John Innes Centre
An exciting opportunity has arisen for a Postdoctoral Researcher to join the Charpentier Group at the John Innes Centre, working on cutting-edge science in the field of plant calcium signalling.
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Reposted by Philippa Borrill
John Innes Centre @johninnescentre.bsky.social · 08/10/2025
Applications are now OPEN for the JIF Rotation PhD Programme This prestigious 4-year #PhD programme trains graduate students in Plant and Microbial Sciences at the JIC, @thesainsburylab.bsky.social and @earlhaminst.bsky.social. 🗓️ Closing date - 13 November 2025 www.jic.ac.uk/training-car...
jic.ac.uk
Rotation biology PhDs | John Innes Centre
Prestigious studentships, for entry in October 2022, this multi-disciplinary PhD programme includes; plant science, microbiology, biological chemistry, applied mathematics…
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Philippa Borrill @philippaborrill.bsky.social · 22/10/2025
Delighted to be selected for the Carlotta Award celebrating female wheat researchers 🎉 Thank you to the committee - it was lovely to meet you in Bari! I am sure this award will continue to promote women's contributions to wheat research under the stewardship of @wheatinitiative.bsky.social
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Philippa Borrill @philippaborrill.bsky.social · 13/10/2025
The mystery of redundancy between homoeologs continues! Knocking out one homoeolog in wheat doesn't cause the other homoeologs to be upregulated... nph.onlinelibrary.wiley.com/doi/10.1111/... Great work led by @delfidorussen.bsky.social with @emilieknight.bsky.social @simmojsimmo.bsky.social
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Philippa Borrill @philippaborrill.bsky.social · 03/10/2025
We are looking for a postdoctoral researcher to join our team! They will work on homeolog-informed approaches to tackle cold tolerance in wheat @johninnescentre.bsky.social Please find out more and apply here: jobs.jic.ac.uk/Details.asp?... #plantsciences #plantscijobs
jobs.jic.ac.uk
John Innes Centre
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Reposted by Philippa Borrill
Christine Faulkner @pdchristine.bsky.social · 18/07/2025
Exciting times to be at @johninnescentre.bsky.social ! www.jic.ac.uk/press-releas...
jic.ac.uk
Major funding boost to bring world leading researchers to the John Innes Centre | John Innes Centre
The John Innes Centre has been awarded an equal share of the new £54 million Global Talent Fund, to attract and support leading researchers and their teams to relocate to the UK. The new Global Talent...
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Reposted by Philippa Borrill
Tung Le @tunglejic.bsky.social · 10/07/2025
Fantastic opportunity to start your independent career at the JIC here. Great startup package. Repost = nice. Thank you!!!
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Reposted by Philippa Borrill
Journal of Experimental Botany @jxbotany.bsky.social · 04/07/2025
🌾🧬 SPECIAL ISSUE RESEARCH 🌾🧬 📝 Varying gene dosage through mutating DNA methyltransferase 1-1 (MET1-1 ) in polyploid wheat generates quantitative changes to CG methylation without the lethal consequences observed in other crops - Burrows et al. 🔗 doi.org/10.1093/jxb/... #PlantScience 🧪
Fig. 1. (short legend see paper for full description): Null met1-1 mutants cannot be produced by crossing TILLING lines with disruptions in the three MET1-1 homoeologues. (A) Evolutionary relationships between MET1 homologues in Arabidopsis (AtMET1), rice (OsMET1a and OsMET1b), and wheat (homoeologue groups TaMET1-1, TaMET1-2, and TaMET1-3). (B) Crossing schematic showing the generation of the hexaploid MET1-1 populations: the C0465×C0884 population (top) and the C0451×C2028×C1292 population (bottom). (C) Structure of the three MET1-1 homoeologues. Filled rectangles represent exons, open rectangles represent untranslated regions, and lines represent introns. Triangles indicate the positions of the premature termination codon mutations in the TILLING lines used to produce the two hexaploid F2 populations (C0465×C0884, orange; C0451×C2028×C1292, purple). The green box signifies the Bromo adjacent homology domain (BAH) and the blue box signifies the C-5 cytosine methyltransferase domain.
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Philippa Borrill @philippaborrill.bsky.social · 02/07/2025
In #wheat mutants we've long wondered if the expression of homoeologs is upregulated to compensate. Could that explain homoeolog redundancy? Spoiler alert: no! Great summary by lead author @delfidorussen.bsky.social ⬇️ and the whole preprint is here: www.biorxiv.org/content/10.1... #plantscience
biorxiv.org
Homoeolog expression in polyploid wheat mutants shows limited transcriptional compensation
Active transcriptional compensation between gene duplicates (paralogs or homoeologs) has been proposed to facilitate functional redundancy, whereby mutations in multiple gene copies are required befor...
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Philippa Borrill @philippaborrill.bsky.social · 24/06/2025
Wonderful to see such a range of plant model organisms featured in @cp-devcell.bsky.social. From crops like wheat and maize all the way through to liverworts, algae & ferns!🌾🌿🌽🥬🦠 Many opinions including why I propose using wheat as a model to investigate polyploidy: doi.org/10.1016/j.de...
doi.org
Redirecting
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Philippa Borrill @philippaborrill.bsky.social · 24/06/2025
It's an honour to be shortlisted for the Falling Walls Foundation Science Breakthrough of the Year 2025 for our work on epigenetics in crop breeding. I'm excited to see where this work leads us! Here we describe our first steps into epigenetic mutants in wheat doi.org/10.1093/jxb/...
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Reposted by Philippa Borrill
John Innes Centre @johninnescentre.bsky.social · 13/06/2025
EVENT - “Fundamental Biology of Legume Crops” Workshop Discuss the latest research in genomics, metabolomics, biotic interactions and plant development. 💻 Application deadline: 16 July 2025 🗓️ 3 - 4 November 2025 📍The John Innes Centre, NR4 7UH Find out more and apply: okt.to/fgZCWB
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Philippa Borrill @philippaborrill.bsky.social · 30/05/2025
Our latest work found that homoeolog expression bias is inherited for ~26% of triads in wheat. Intriguingly we found that new patterns of homoeolog expression bias are more frequent when one of the parents is a landrace. Read more in Genome Biology: rdcu.be/eokf2 @johninnescentre.bsky.social
rdcu.be
Rapid reprogramming and stabilization of homoeolog expression bias in hexaploid wheat biparental populations
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Philippa Borrill @philippaborrill.bsky.social · 23/05/2025
Looking for the direct target genes of a transcription factor in #wheat? Our protocol uses protoplasts, skipping transgenic plants to save months! Great step by step protocol @emilieknight.bsky.social! Read more below ⬇️ Thanks to all contributors! #plantscience @johninnescentre.bsky.social
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Philippa Borrill @philippaborrill.bsky.social · 07/05/2025
It was a pleasure to host @ismaelgf.bsky.social for 3 months @johninnescentre.bsky.social. Looking forward to continuing our collaboration with @irnasa.bsky.social on transcriptomic responses to water deficit in wheat 💦🍞🌾
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Reposted by Philippa Borrill
Nikolai Adamski @nikolaiadamski.bsky.social · 10/04/2025
#Monogram2025 has finished. It was a fantastic conference with outstanding speakers and great interactions. I am very grateful to the organisers for their hard work!! (Especially Ash!) Looking forward to next year's conference hosted by NIAB. @monogram-uk.bsky.social @niab-uk.bsky.social
A picture showing the attendees of the Monogram2025 conference in Aberystwyth. A picture of Dr Aiswarya Girija (Ash) receiving a thank you for her work coordinating the organisation if Monogram2025.A picture showing the people who helped organise Monogram2025. A picture revealing that Monogram2026 will be hosted by the NIAB institute in Cambridge.
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Philippa Borrill @philippaborrill.bsky.social · 10/04/2025
Congratulations to Isabel Faci @johninnescentre.bsky.social winner of the #Monogram2025 ECR excellence award! Fascinating talk on how decoupling environmental signals can induce aerial branching in wheat!
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Philippa Borrill @philippaborrill.bsky.social · 10/04/2025
Congratulations to @katielong.bsky.social @johninnescentre.bsky.social winner of the #Monogram2025 ECR excellence award! Fabulous talk on the intricate patterns of gene expression in wheat spikes!
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Philippa Borrill @philippaborrill.bsky.social · 09/04/2025
Wonderful talk from @delfidorussen.bsky.social at #Monogram2025 about DNA methylation mutants in wheat. You can read the full MET1-1 mutant characterisation which was just published this week @jxbotany.bsky.social ⬇️
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Philippa Borrill @philippaborrill.bsky.social · 09/04/2025
Really enjoying #Monogram2025 so far @ibers.bsky.social Great talk by @chen-ji.bsky.social on her latest work exploring gene expression patterns in wheat grains. So many interesting genes to characterise!
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Reposted by Philippa Borrill
Delfi Dorussen @delfidorussen.bsky.social · 08/04/2025
I’m very happy to share the published version of our paper on the role of MET1 in wheat 🌾 🧬 It’s been really exciting to discover more about DNA methylation in wheat and it’s huge polyploid genome doi.org/10.1093/jxb/...
doi.org
Partial redundancy buffers deleterious effects of mutating DNA methyltransferase 1-1 (MET1-1) in polyploid wheat
Varying gene dosage through mutating DNA methyltransferase 1-1 (MET1-1 ) in polyploid wheat generates quantitative changes to CG methylation without the le
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Philippa Borrill @philippaborrill.bsky.social · 04/04/2025
Looking forward to #Monogram2025 next week. Check out the programme below ⬇️ @monogram-uk.bsky.social
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Philippa Borrill @philippaborrill.bsky.social · 13/03/2025
Starting to build our lab's interactions on bluesky. It appears we've got a positional effect from the summer lab photo 😂... @delfidorussen.bsky.social @chen-ji.bsky.social @beccatesta.bsky.social ... but not for alumnus @glombikm.bsky.social (top left of photo) @johninnescentre.bsky.social
Group photo of Borrill lab team with 4 bluesky account holders indicated by bluesky butterfly icon.
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Philippa Borrill @philippaborrill.bsky.social · 06/02/2025
Come hear Chen Ji talk about her fascinating results from spatial transcriptomics in wheat. There will be lots of beautiful images of gene expression patterns! 🗓️18-19 June in Norwich, UK Registration is open ⬇️
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Philippa Borrill @philippaborrill.bsky.social · 14/01/2025
Congratulations @delfidorussen.bsky.social on being awarded the #IWGSC -Feuillet Early Career award to present your work on #wheat homoeolog transcriptional compensation at PAG.🌾 #ProudPI.
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