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Imran S. Haque

@ihaque.bsky.social
1.5K followers 1.1K following 55 posts

CTO at Kimia Therapeutics. Formerly SVP AI at Recursion. ihaque.org x.com/ImranSHaque

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Reposted by Imran S. Haque
Reese Richardson @reeserichardson.bsky.social · 05/06/2026
ALSO: the repository now contains 1 example from Abcam's catalog! Curiously, this image features the same "background pattern A" as hundreds of Thermo Fisher images, suggesting that it was sourced from the same third-party lab. www.abcam.com/en-us/produc...
abcam.com
Anti-HC-II antibody (ab196758) | Abcam
Rabbit Polyclonal HC-II antibody. Suitable for WB and reacts with Human samples. Immunogen corresponding to Synthetic Peptide within Human SERPIND1.
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Ana Matoso @anamatoso.bsky.social · 17/10/2025
If you ever done an MRI you know about all the weird sounds it makes. Well, weird no more! There's a sequence (MRF-Music) that makes the sounds you hear during an MRI to play at the beat of any song you want. This will make the exam much more tolerable and confortable Link: tinyurl.com/bdhwnsak
pmc.ncbi.nlm.nih.gov
Music-Based Magnetic Resonance Fingerprinting to Improve Patient Comfort During MRI Exams
The unpleasant acoustic noise is an important drawback of almost every magnetic resonance imaging scan. Instead of reducing the acoustic noise to improve patient comfort, a method is proposed to mitig...
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Dr Kat Day (she/her) 🌖 @chronicleflask.katday.com · 28/09/2024
This graph is astonishing. The people that bang on about “natural birth” and “women have been doing this forever without help” need to be forced to stare at this until their eyes water.
Graph of maternal mortality rate against year for the UK. Rate bounces until and down around 500 deaths per 100,000 births until about 1940, when it falls sharply. It’s been very low (~1–3 per 100,000) ever since.
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Jacob Tennessen @jacobphd.bsky.social · 20/05/2025
No... one... Pipes like gaston Mends stats gripes like gaston No one analyzes genotypes like gaston
Description of R package gaston from https://cran.r-project.org/web/packages/gaston/gaston.pdf
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Helen Branswell 🇨🇦 @helenbranswell.bsky.social · 12/04/2025
Can the #HHS agencies continue to function, given the deep cuts to administrative staff in the recent layoffs? Employees of these agencies are expressing deep fears that so much of the scaffolding is gone that the edifices could crumble. www.statnews.com/2025/04/11/h...
statnews.com
Inside U.S. health agencies, workers confront chaos and questions as operations come unglued
The Trump administration’s remaking of HHS — in a matter of weeks — is sparking basic questions about how parts of the agency and those it oversees can continue to function.
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The New York Times @nytimes.com · 05/04/2025
Here is a look at how measles — one of the world’s most infectious viruses — takes over the body.
nytimes.com
How Measles Attacks an Unvaccinated Child
With falling vaccination rates and outbreaks that have caused more than 580 U.S. cases and at least one death, health experts expect hundreds or even thousands more to be infected in the coming months...
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Needhi Bhalla 💅🏽 @needhibhalla.bsky.social · 31/03/2025
I think this opinion piece also demonstrates what arguments are likely to be the most convincing to your representative, if they are a Republican
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Science Magazine @science.org · 31/03/2025
Using data on more than 220,000 individuals on Lyft, researchers report in Science that drivers of color are significantly more likely to receive speeding tickets than white drivers, and to face steeper fines, even when traveling at identical speeds. scim.ag/3QYTjOO
scim.ag
High-frequency location data show that race affects citations and fines for speeding
Prior research on racial profiling has found that in encounters with law enforcement, minorities are punished more severely than white civilians. Less is known about the causes of these encounters and...
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Imran S. Haque @ihaque.bsky.social · 19/03/2025
Thrilled to announce that I've joined @kimia-tx.bsky.social as chief technology officer. Kimia's one-of-a-kind chemistry platform is an incredible data engine for building foundation models of chemistry and applying them to dramatically accelerate exploration of small molecule space.
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Randall Munroe @xkcd.com · 17/03/2025
Lungfish xkcd.com/3064
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Reto Fiolka @retof.bsky.social · 06/03/2025
Zeiss has released its light field microscope! zeiss.wistia.com/medias/otnxx...
zeiss.wistia.com
Lightfield 4D: Instant volumetric imaging of a beating embryonic zebrafish heart
Courtesy of Stone Elworthy and Emily Noël, School of Biosciences, University of Sheffield, UK
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Imran S. Haque @ihaque.bsky.social · 21/02/2025
@kylegriffin1.bsky.social looks like your X account got hacked.
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Recursion @recursionpharma.bsky.social · 19/02/2025
Today, Recursion is announcing a new pre-seed venture fund – the Altitude Lab Fund – to address the #SBIR funding gap hitting early-stage #biotech startups. The fund is backed by Recursion co-founder & CEO Chris Gibson & biotech entrepreneur David Bearss. techcrunch.com/2025/02/19/n...
techcrunch.com
NIH funding uncertainty spurs new biotech venture fund | TechCrunch
Earlier this month, the Trump administration directed the National Institutes of Health (NIH) to impose limits on specific types of funding it provides to
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Imran S. Haque @ihaque.bsky.social · 19/02/2025
Proud to see @recursionpharma.bsky.social and Altitude Lab step up to support new translational endeavors in this time of uncertainty for sci funding with the new Altitude Lab Pre-Seed Venture Fund, helping those otherwise waiting on SBIR. See more on @techcrunch.com: techcrunch.com/2025/02/19/n...
techcrunch.com
NIH funding uncertainty spurs new biotech venture fund | TechCrunch
Earlier this month, the Trump administration directed the National Institutes of Health (NIH) to impose limits on specific types of funding it provides to
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Sri Kosuri @srikosuri.bsky.social · 08/02/2025
It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS or other (non-LCH) dendritic or histiocytic sarcomas cases.
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Recursion @recursionpharma.bsky.social · 05/02/2025
Today, Dr. Jan-Karl Burkhardt, MD, MBA, Division Head of Cerebrovascular Surgery at University of Pennsylvania, shared Phase 2 data for REC-994 -- the 1st industry initiated trial in #CCM - in a late-breaking oral presentation at the International Stroke Conference. ir.recursion.com/news-release...
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Itai Yanai @itaiyanai.bsky.social · 23/01/2025
Sometimes the experimental control is messed up – but in a really interesting way! – and it's a great 'night science' trick to make a discovery by recognizing it when it happens.
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Imran S. Haque @ihaque.bsky.social · 18/01/2025
Well, it's not done up in Millennial Gray, I'll give it that.
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Ash Jogalekar @ashjogalekar.bsky.social · 17/01/2025
I have a new blog devoted to medicinal chemistry in which I will mainly focus on classic papers. My first installment describes the design and discovery of the amazing atorvastatin: a triumph of simple modeling, dogged synthesis and leadership decisions medchemash.substack.com/p/classics-i...
medchemash.substack.com
Classics in Medicinal Chemistry #1: Atorvastatin
Lipitor
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Jeremy Berg @jeremymberg.bsky.social · 17/01/2025
Bluetorial: When the leadership of Science magazine does not seem to care about getting the facts right in a news story... A very troubling incident occurred some years ago and I think the concerns and lessons are important. My apologies for the length, but it is a complicated story.
media.tenor.com
a cartoon says hey everybody an old man 's talking while bart simpson looks on
ALT: a cartoon says hey everybody an old man 's talking while bart simpson looks on
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Christie Wilcox @nerdychristie.bsky.social · 17/01/2025
Small AI-designed proteins neutralized one of cobras' nastiest venom toxins. The findings raise the question: Could AI bring antivenoms into the 21st century? That and more of the best from @science.org and science in this edition of #ScienceAdviser: www.science.org/content/arti... 🧪
So-called binder proteins (right), designed by AI, protected cells and mice from lethal doses of 3-finger toxins better than the antibodies used in conventional antivenom (left).  Timothy Jenkins
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Recursion @recursionpharma.bsky.social · 13/01/2025
Advancing our vision for a virtual cell: In a presentation at #JPM2025, CEO Chris Gibson shared his vision for #TechBio, in which biol & chem datasets & highly predictive ML models, including advanced protein folding, will allow us to build a true virtual cell. ir.recursion.com/static-files...
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Recursion @recursionpharma.bsky.social · 07/01/2025
👉 Read more: ir.recursion.com/news-release...
ir.recursion.com
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Recursion @recursionpharma.bsky.social · 07/01/2025
🔹 Using our AI platform, REC-3565 was designed as a highly selective MALT1 inhibitor that could mitigate potential risks of drug-drug interaction/hyperbilirubinaemia, enhancing its potential in combination therapies. There are ~41k R/R patients w/ CLL & B-cell lymphomas in the US & EU5 annually. 🧵
ir.recursion.com
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Recursion @recursionpharma.bsky.social · 07/01/2025
🔹 Designed & optimized using AI & active learning, REC-4539 is the first reversible LSD1 inhibitor that not only targets peripheral disease but is also designed to penetrate the brain, addressing a critical unmet need. There are ~45k patients with extensive stage SCLC in the US & EU5 annually. 🧵
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Recursion @recursionpharma.bsky.social · 07/01/2025
📣 Big news ahead of JPM: 2 of our key investigational oncology drugs have received regulatory approval to advance to clinical trials: REC-4539 – potential best-in-class LSD1 inhibitor for SCLC & other indications & REC-3565 – a potential best-in-class MALT1 inhibitor for B-cell malignancies. 🧵
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Tim Triche, Jr.🔰 @timtriche.bsky.social · 04/01/2025
Which reminds me, if you have any doubt that our immune systems can use all the help we are able to provide, here is a summary of causes of death in Boston in 1912. Please for the love of your fellow man support antibiotics and vaccination. Source: www.nejm.org/doi/full/10....
1900: flu, tuberculosis, gastroenteritis
2010: heart disease, cancer, COPD
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Mark Dawson @mafdawson.bsky.social · 02/01/2025
Why can a human tolerate a drug that globally inhibits transcription? Why do transcription inhibitors not cure cancer? Our first paper of 2025 may help explain (some) of this! So incredibly proud of @tobiaswilliams.bsky.social & Ewa Michalak who led the work! www.cell.com/molecular-ce...
cell.com
mRNA export factors store nascent transcripts within nuclear speckles as an adaptive response to transient global inhibition of transcription
Transcription inhibitors also disrupt nuclear export. Here, Williams et al. reveal that mRNA export factors sense transcription inhibition and adapt by storing mature export-competent mRNA in nuclear speckles. This enables rapid release when transcription resumes and ensures retention of cellular identity and viability during a transient global transcription insult.
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Imran S. Haque @ihaque.bsky.social · 30/12/2024
Amazing, no notes
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Mark Peifer (He, him) @peiferlabunc.bsky.social · 29/12/2024
WOW! "Subtomogram averaging Soluble and membrane-bound complexes ranging in size from >3 MDa to ~200 kDa, including 80S ribosomes, Rubisco, nucleosomes, microtubules, clathrin, photosystem II, and mitochondrial ATP synthase. The majority of these density maps reached sub-nanometer resolution..." 🧪
Title, authors and abstract from link
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Peyman Milanfar @docmilanfar.bsky.social · 27/12/2024
It's important to distinguish between supporting legal immigration generally and advocating specifically for tech immigration to fill high-skilled jobs. While both positions have merit, they're driven by different motivations and have distinct implications. 1/n
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Frank S. David @franksdavid.bsky.social · 24/12/2024
“We should not include plots in scientific papers just to make them aesthetically pleasing. Plots should communicate findings, not decorate.” Good post by @rafalab.bsky.social HT @michaelhoffman.bsky.social
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Nessa Carson @supersciencegrl.co.uk · 22/12/2024
Interviewer: Can you explain this gap on your CV? Chemist: Yeah, that's what's between the HOMO and the LUMO #chemsky
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Gaël Varoquaux @gaelvaroquaux.bsky.social · 22/12/2024
If you work with Python dataframes (pandas, @pola.rs) and are not using skrub.TableReport, you're missing out 😀 We keep improving it
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Imran S. Haque @ihaque.bsky.social · 22/12/2024
Is Gemini just uniquely stupid?
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ProPublica @propublica.org · 19/12/2024
NEW: Women experiencing pregnancy loss in states with abortion bans told us they wished they had known what to expect and how to advocate for themselves. We created this guide for anyone who finds themselves in the same position. ⤵️
propub.li
If You’re Pregnant, Here’s What You Should Know About the Medical Procedures That Could Save Your Life
Women experiencing pregnancy loss in states with abortion bans told us they wished they had known what to expect and how to advocate for themselves. We created this guide for anyone who finds…
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Kristina Ulicna @kristinaulicna.bsky.social · 19/12/2024
Exciting news! 🚀 The Learning Meaningful Representations of Life ( #LMRL 🌟) workshop is returning at #ICLR2025! 🎉 On 27th / 28th April 2025 in Singapore 🇸🇬, this popular event returns with a fresh organizing team 👇 & bold new ideas 🧠 to explore bridging AI & life sciences 🧬
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Imran S. Haque @ihaque.bsky.social · 19/12/2024
.@drughunter.com is here now!
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Carolyn Bertozzi @carolynbertozzi.bskyverified.social · 15/12/2024
Great description by @jeremymberg.bsky.social on the experience of a scientist serving as an expert witness
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Michael Fischbach @mfgrp.bsky.social · 11/12/2024
Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. @djenetbousbaine.bsky.social led the charge... @natureportfolio.bsky.social 1/55
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Recursion @recursionpharma.bsky.social · 10/12/2024
REC-617 is a testament to the potential of #AI guided precision chemistry & design to deliver new #cancer treatments. Today, we presented the latest interim data for our monotherapy Phase 1 trial for REC-617, a potential best-in-class CDK7 inhibitor, in a live Update Call. 🧵
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Recursion @recursionpharma.bsky.social · 09/12/2024
Dr. Hallett: “Cell cycle dysregulation & transcriptional 'addiction' are both hallmarks of many aggressive cancers. By inhibiting CDK7, we have the potential to target both mechanisms while fine tuning the therapeutic index.” Learn more & join the update call 12/10: ir.recursion.com/news-release...
ir.recursion.com
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Recursion @recursionpharma.bsky.social · 09/12/2024
▫️ Confirmed partial response (PR) during monotherapy dose-escalation in a patient with platinum-resistant ovarian cancer, treated with 4 lines of prior therapy in an advanced setting, with durable response ongoing after more than 6 months of treatment; 🧵
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Recursion @recursionpharma.bsky.social · 09/12/2024
Today at the @theaacr.bsky.social Special Conference in Cancer Research, our CSO David Hallett, PhD shared interim monotherapy dose-escalation data from the Phase 1/2 study (ELUCIDATE) of REC-617, a selective CDK7 inhibitor, in advanced solid tumors. Here's what was revealed. 🧵
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Imran S. Haque @ihaque.bsky.social · 09/12/2024
If you asked them ‘ok but HOW tall is it?’, they’d just say INFINITY. But here it’s not just infinite, but a specific infinite number divided by 4. Let me tell you, people look at you funny if you say something is infinity over 4 tall. alok.github.io/2024/09/28/d...
alok.github.io
Derivative AT a Discontinuity
Alok Singh's Blog
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Brian Naughton @btnaughton.bsky.social · 30/11/2024
New blogpost: The ABCs of Alphafold 3, Boltz and Chai-1 blog.booleanbiotech.com/alphafold3-b...
blog.booleanbiotech.com
Boolean Biotech
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Recursion @recursionpharma.bsky.social · 27/11/2024
Planning to attend the Superbowl of ML conferences? #NeurIPS (@neuripsconf.bsky.social) is coming to Vancouver Dec. 10-15 & @valenceai.bsky.social will be on site presenting 10+ accepted papers & cohosting a “Night of Science” #TechBio social w/ us & NVIDIA on Thurs. 12/12 👉 RSVP: lu.ma/biikt7ox
lu.ma
A Night of Science with Recursion, Valence Labs, and NVIDIA @ NeurIPS 2024 · Luma
Recursion, Valence Labs, and NVIDIA is thrilled to extend an invitation to researchers, professors, investors, founders, students, and others interested in…
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Cas @caswognum.nl · 27/11/2024
Wow! 🤩 This may be the most carefully documented dataset on @polarishq.bsky.social. Great work by @roman-bushuiev.bsky.social! Do I have any #MassSpec researchers in my 🦋 network yet? I would love to hear what you think! github.com/polaris-hub/... #mass #spectrometry #dataset #benchmark
polarishub.io
massspecgym
roman-bushuiev
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James Stevenson @allaboutchemist.bsky.social · 27/11/2024
Fascinating thread here: apparently, caffeine and ibuprofen both have binding affinity to their target proteins so weak that they might get tossed out of a typical drug discovery project!
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Imran S. Haque @ihaque.bsky.social · 25/11/2024
Is there any way to disable new follower notifications in the Android bsky client? Having landed in a starter pack or two, these are now drowning out signal like actual thread replies...
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