iiinova — where your digital self keeps evolving

Reposted by Marta Siborova

Victor Klein-Sousa @vkleinsousa.bsky.social · 16/09/2026

I'm happy to share one of my favorite projects from the past 4 years. 'Piercing mechanism in the minimal contractile tail of bacteriophage P2'. In this preprint, we applied #cryo-EM, #cryo-ET, TEM, and #computationalbiology to study the #phage P2 virion structure and its contraction mechanism.

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Reposted by Marta Siborova

Ján Bíňovský @jbinovsky.bsky.social · 02/07/2026

🔥My first (co)first-author paper is out🔥 The surfaces of Gram+ and Gram- bacteria are markedly different from each other. How are phages equipped to breach the Gram+ envelope❓ 💡We report a baseplate structure uniquely adapted to infect Gram+ S. aureus. A 🧵⬇️ 1/8 #phagesky #cryoEM 🧪

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RCSB Protein Data Bank @rcsbpdb.bsky.social · 16/05/2026

Try this new online training game from Leandro F. Estrozi designed for newcomers in structural biology, with a focus on cryo-EM and cryo-ET map interpretation: rico.ibs.fr/helixplo...

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Reposted by Marta Siborova

The Daum Lab @daumlab.bsky.social · 24/11/2025

An exciting PhD opportunity is available in my lab! More info about our group and research can be found here: bdaum2.wixsite.com/daumlab Application deadline: 8th Jan 2026. Apply here: www.exeter.ac.uk/study/pg-res... If you are interested, get in touch! #ArchaeaSky #CryoEM #TeamTomo

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RedPen/BlackPen @redpenblackpen.bsky.social · 15/10/2025

What's in yer basement?

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Pedro Leão @pedroleao.bsky.social · 24/09/2025

"Breakthroughs rarely announce themselves on the good days — they are earned quietly, by refusing to quit on the lousy ones, even when impostor syndrome tells you otherwise." open.substack.com/pub/leaopel/...

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Reposted by Marta Siborova

Joost Snijder @joostsnijder.bsky.social · 22/07/2025

We sequenced the anti-RSV-F antibody 131-2a by mass spec and determined its epitope by cryoEM. New insights in postfusion specific binding and antigenic site I. Now published in ACS Infectious Diseases @pubs.acs.org. pubs.acs.org/doi/10.1021/... @xdh.bsky.social @hangryhobbit.bsky.social

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CEITEC @ceitec.eu · 02/07/2025

Structural biologist Pavel Plevka from CEITEC Masaryk University has been elected a new member of the prestigious European Molecular Biology Organization (@embo.org). Congratulations! 👏 Read more here ➡️ www.ceitec.eu/pavel-plevka... #CEITECScience @plevkalab.bsky.social

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Reposted by Marta Siborova

Scripps Research @scripps.edu · 23/04/2025

Scripps Research and @pittofficial.bsky.social capture the first cryo-EM & cryo-ET images of a virus infecting TB-causing Mycobacteria, revealing an unexpected infection mechanism that could inform phage therapies for drug-resistant TB, per @cellpress.bsky.social.

scripps.edu

The very first structural images of a tuberculosis-fighting virus

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Reposted by Marta Siborova

Sergio Cruz-León @sergiocruzleon.bsky.social · 11/04/2025

Excited to share our preprint on the molecular architecture of heterochromatin in human cells 🧬🔬w/ @jpkreysing.bsky.social, @johannesbetz.bsky.social, @marinalusic.bsky.social, Turoňová lab, @hummerlab.bsky.social @becklab.bsky.social @mpibp.bsky.social 🔗 Preprint here tinyurl.com/3a74uanv

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Oded Rechavi @odedrechavi.bsky.social · 24/03/2025

We continue working on the plans for the "Woodstock of Bioloy 2 & Night science in Prague" meeting and if you don't sign up you're totally crazy. A once in a life time opportunity and it'll be sold out soon. Go to the website and sign up now before it's too late!

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Reposted by Marta Siborova

Dominik Hrebik @dhrebik.bsky.social · 03/03/2025

I am very happy to announce that we solved the in-virus #cryoEM structure of the #HIV matrix protein. The structure helped us to resolve a long mystery in HIV biology. A🧵1/5 Read more in Nature: www.nature.com/articles/s41... 🧪

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Reposted by Marta Siborova

Joost Snijder @joostsnijder.bsky.social · 06/01/2025

We sequenced the anti-RSV-F antibody 131-2a by mass spec, then mapped its epitope by cryoEM. It's widely used to study the antigenic landscape of F, but its sequence wasn't known. Check it out in our new preprint and find it on Addgene: www.biorxiv.org/content/10.1... www.addgene.org/Joost_Snijder/

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Reposted by Marta Siborova

STCmicrobeblog @stcmicrobeblog.bsky.social · 26/11/2024

@hangryhobbit.bsky.social glad to see you here on 🔵bsky, marta 🙂 let's celebrate Happy #WorldPhageDay 🎉 here too... #PhageSky

from https://x.com/HangryHobbit/status/1451522800968212512

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Reposted by Marta Siborova

Elizabeth Stokoe @lizstokoe.bsky.social · 24/11/2024

2/15 "How are you" is often deemed a 'pointless' or 'filler' question, to which the socially acceptable answer might be a lie ("fine, how are you?"). "How are you" should not be taken as an opportunity to "discuss the crushing reality of existence", says Machell's Guide to Surviving Modern Life.

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Reposted by Marta Siborova

Ján Bíňovský @jbinovsky.bsky.social · 23/09/2024

🚀Announcing my first (co)first-author manuscript 🚀 "Cell attachment and tail contraction of S. aureus phage phi812" 🔗 bit.ly/Phi812 Explore the structural details of phage interaction with Gram+ bacteria 🤯 #PhageTherapy #cryoEM 🧪 | 🧬🧶 | 🦠 1/11

bit.ly

Cell attachment and tail contraction of S. aureus phage phi812

bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution

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Reposted by Marta Siborova

c0nc0rdance @c0nc0rdance.bsky.social · 02/11/2023

You're looking at one of the first electron micrographs of T-even bacteriophage, taken by Tom Anderson of RCA labs, published with Luria & Delbrück. On seeing the images, famed immunologist Jacques Bronfonbrenner exclaimed: “Mein Gott, they’ve got tails!”

some T-even phage are indistinct in a micrograph, with a hand-drawn scale bar labeld as 1 mu (micron). Source in next skeet.

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