Published in Nucleus (Vol. 17, No. 1, 2026)

In this Comment, we call on scientists to share their stories. Through casual conversation or prepared presentations, with images or essays, scientists can advocate for their research and reach taxpay...

Innovations in imaging and genetic engineering are coming together to probe the biophysics of cytoplasm inside living animals.

Innovations in imaging and genetic engineering are coming together to probe the biophysics of cytoplasm inside living animals.

Network, learn, and collaborate with top cell biologists from around the globe.

Shen, Gelashvili and Niethammer developed an inner nuclear membrane tension sensor and demonstrated that ER–nuclear membrane contiguity acts as a mechanical buffer.

Leading a lab is both a venture and an adventure. It’s double that for these researchers.

Mary Brunkow, Fred Ramsdell, and Shimon Sakaguchi discovered regulatory T cells that prevent autoimmune disease

Mary Brunkow, Fred Ramsdell and Shimon Sakaguchi discovered cells that protect the body from autoimmune diseases.

Living tissues maintain unique intracellular biophysical properties under the control of cytoplasmic constraints and crowding.

Nuclear migration plays a fundamental role in development, requiring precise spatiotemporal control of bidirectional movement through dynein and kines…

YouTube video by Morris Maduro

The midbody (MB), a transient structure formed during cytokinesis, has evolved from a mere structural component to a complex signaling organelle with diverse functions beyond cell division. Recent stu...

Summer courses can shape one's science and change one's life, too.

Some graduate students, postdoctoral fellows and senior researchers choose a special kind of science-focused summer.

The nuclear pore complex (NPC) is a large multi-protein structure that enables movement of macromolecules, such as mRNA and proteins, between the nucleoplasm and cytoplasm. There has been great intere...

Nuclei adjust their deformability while migrating through constrictions to enable structural changes and maintain nuclear integrity. The effect of heterochromatin anchored at the nucleoplasmic face of...

Wolfenson et al. recall the life and many contributions of Michael Sheetz, who passed away on January 30, 2025.

Injunction allows universities to keep receiving billions to recover costs of supporting federal research on campus

Nesprin-2 Giant links the nucleus to the cytoskeleton, enabling actin transport and nuclear movement through kinesin-1 activation.

Underneath the darkness and surrealism, the work of David Lynch contained a pure, earnest belief in beauty and love. He will be missed.

The Oscar-nominated writer and filmmaker is famous for the film Mulholland Drive and the TV series Twin Peaks.

Understanding how cells control their biophysical properties during development remains a fundamental challenge. While cytoplasmic macromolecular crowding affects multiple cellular processes in single...