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Xiangyi Ding @xiangyiding.bsky.social · 22/07/2026

Excited to share that the third chapter of my dissertation is now on bioRxiv! We found that the LINC complex acts as a brake to gate nucleolar assembly in C. elegans embryos. Grateful to Gant, Dan, Steph, and all our co-authors for making this work possible. www.biorxiv.org/content/10.6...

biorxiv.org

| bioRxiv

bioRxiv - the preprint server for biology, operated by openRxiv, a nonprofit organization dedicated to advancing scientific communication

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Reposted by Xiangyi Ding

GW Gant Luxton @gwgl.bsky.social · 19/02/2026

New in @quantamagazine.bsky.social: the science of cytoplasmic crowding. From Liam Holt & Simone Reber's work to our discovery that in vivo cytoplasm is 50x more crowded than cultured cells. Thanks @danstarrucdavis.bsky.social & @gabepopkin.bsky.social! www.quantamagazine.org/the-biophysi...

quantamagazine.org

The Biophysical World Inside a Jam-Packed Cell | Quanta Magazine

Innovations in imaging and genetic engineering are coming together to probe the biophysics of cytoplasm inside living animals.

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Xiangyi Ding @xiangyiding.bsky.social · 07/12/2025

Dear friends at ASCB, I’ll be giving a talk tomorrow at the minisymposium of Structure, Function and Mechanics of Nuclear Envelope, at 11:00 am in Room 118. Come talk with me and all other Starr-Luxton Lab folks here at ASCB Matt, Dan and Gant and let’s get connected! #ASCB #CellBio2025

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Reposted by Xiangyi Ding

Debraj Ghose @debrajghose.bsky.social · 19/11/2025

Immune tissue behaves as shapeshifting active living matter as it fights intruders. Using liquid-like multicellular B cell droplets, we show that cytokines control the physical state of immune tissue. www.biorxiv.org/content/10.1... youtu.be/QAk2ayoVF0M #biophysics #immunology #activematter

youtu.be

Movie S2 20230517

YouTube video by Debraj Shubham Ghose

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Xiangyi Ding @xiangyiding.bsky.social · 23/09/2025

🎉Check out our new preprint!! 🧬We found that lamin mutations in muscular dystrophy don’t just affect the nucleus — they disrupt a nucleolar–ribosomal axis that reorganizes the entire cytoplasm. Very grateful to @danstarrucdavis.bsky.social, @gwgl.bsky.social and our lab for collaboration & support!

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Reposted by Xiangyi Ding

GW Gant Luxton @gwgl.bsky.social · 10/09/2025

🧬BREAKING!🪱Plot twist: Cells aren't meditation pools, they're overcrowded concerts with VIP ropes everywhere! Our study reveals worm cells are insanely crowded AND compartmentalized. Ribosomes = packing peanuts, ANC-1 = the bouncer! www.science.org/doi/10.1126/...

science.org

Giant KASH proteins and ribosomes establish distinct cytoplasmic biophysical properties in vivo

Living tissues maintain unique intracellular biophysical properties under the control of cytoplasmic constraints and crowding.

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Xiangyi Ding @xiangyiding.bsky.social · 10/09/2025

Thrilled to share that a big piece of my thesis here in the Starr–Luxton is now out in Science Advances! We discovered that the cytoplasm of living animal tissues is extremely crowded and constrained, maintained by ribosomes and the giant KASH protein ANC-1. www.science.org/doi/10.1126/...

science.org

Giant KASH proteins and ribosomes establish distinct cytoplasmic biophysical properties in vivo

Living tissues maintain unique intracellular biophysical properties under the control of cytoplasmic constraints and crowding.

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Reposted by Xiangyi Ding

GW Gant Luxton @gwgl.bsky.social · 09/09/2025

🚨Our fabulous graduate student Selin's paper on how the KASH protein UNC-83 regulates the activity of kinesin-1 to control developmental stage-specific nuclear migration is out! Another great collaboration between the Starr-Luxton and MOM labs. www.sciencedirect.com/science/arti...

sciencedirect.com

The KASH protein UNC-83 differentially regulates kinesin-1 activity to control developmental stage-specific nuclear migration

Nuclear migration plays a fundamental role in development, requiring precise spatiotemporal control of bidirectional movement through dynein and kines…

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Reposted by Xiangyi Ding

Genetics Society of America @genetics-gsa.bsky.social · 25/06/2025

Ellen Gregory, @gwgl.bsky.social‬, & @danstarrucdavis.bsky.social‬ show how heterochromatin helps cell nuclei migrate through tight spaces in #Celegans! Learn more in #GENETICS about the process of heterochromatin anchoring to the nuclear periphery that supports nuclei squeezing: buff.ly/kZttVdX

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Xiangyi Ding @xiangyiding.bsky.social · 30/06/2025

It was great to gave a plenary talk to the worm community 🪱 Received great questions and comments. Thanks to both of my PIs @gwgl.bsky.social and @danstarrucdavis.bsky.social for the co-mentorship and thanks to the organizers @genetics-gsa for bringing us together.

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