Long-read sequencing provides a more complete view of the genome than short-read sequencing, with advantages in the detection of structural variants, tandem repeats, and small variants (single nucleot...

ALT: a cartoon says hey everybody an old man 's talking while bart simpson looks on

AI is transforming grant writing—turning a time-intensive task into a more strategic, efficient process that elevates both research and storytelling. This hands-on course explores how to integrate AI ...

Analysis of more than 95% of each diploid human genome of a four-generation, twenty-eight-member family using five complementary short-read and long-read sequencing technologies provides a truth set t...

A conversational AI system that listens, learns, and challenges

A conversational AI system that listens, learns, and challenges

A conversational AI system that listens, learns, and challenges

Approximately 8% of the human genome consists of repetitive elements called tandem repeats (TRs): short tandem repeats (STRs) of 1–6 bp motifs and variable number tandem repeats (VNTRs) of 7 + bp moti...

Approximately 8% of the human genome consists of repetitive elements called tandem repeats (TRs): short tandem repeats (STRs) of 1–6 bp motifs and variable number tandem repeats (VNTRs) of 7 + bp moti...

Bispecific antibodies incorporating a cross-reactive NTD-specific antibody are resilient to SARS-CoV-2 variants of concern.

In this work, high-throughput microfluidic assays reveal how allosteric substitutions that alter folding-and-binding pathways shape DNA specificity and selectivity landscapes in the human…

OpenAI made GPT-4.5 available to Plus ($20/month) users today. I was [a little disappointed](https://simonwillison.net/2025/Feb/27/introducing-gpt-45/) with GPT-4.5 when I tried it through the API, bu...

New SPRQ chemistry for the Revio system is revolutionizing HiFi sequencing with increased efficiency, affordability, and reduced DNA input. Learn about its impact on research in rare diseases, cancer, and multiomics.

Staphylococcus aureus is a leading cause of bacteria-associated mortality worldwide. This is largely because infection sites are often difficult to localize and the bacteria forms biofilms which are n...

A drug with a novel mechanism protects people against the AIDS virus for 6 months. It could speed the end of the epidemic—if those who need it most get access