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Ghanendra Singh

@ghanendra.bsky.social
64 followers 430 following 22 posts

Research Interests in astrocytes, working memory, neuromorphic computing. Looking for PhD positions. sghanendra.github.io

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Reposted by Ghanendra Singh
Papouin Lab @ WashU @papouinlab.bsky.social · 16/05/2025
Thought this would be a nice way to enter the bsky community👇Delighted for Katie (now in Chris Dulla's lab at Tufts). Thank you to our collaborators, to the reviewers and to Cagla Eroglu for the highlight! www.science.org/doi/10.1126/...
science.org
Norepinephrine signals through astrocytes to modulate synapses
Locus ceruleus (LC)–derived norepinephrine (NE) drives network and behavioral adaptations to environmental saliencies by reconfiguring circuit functional connectivity, but the underlying synapse-level...
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Reposted by Ghanendra Singh
Amit Agarwal @agarwal-neurolab.bsky.social · 02/01/2026
We identified how mechanical forces shape myelin development. The TMEM63A channel in oligodendrocytes converts physical cues into molecular signals that control myelin growth. Oligodendrocyte mechanotransduction channel TMEM63A regulates myelin sheath geometry: Neuron www.cell.com/neuron/fullt...
cell.com
Oligodendrocyte mechanotransduction channel TMEM63A regulates myelin sheath geometry
Dereddi, Djannatian, and colleagues show that oligodendrocytes use mechanical cues to measure axon size. The stretch-activated channel TMEM63A converts membrane tension into calcium signals, which cal...
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Ghanendra Singh @ghanendra.bsky.social · 12/02/2026
Motivated reasoning with confirmation bias: Sometimes “We don’t reason to discover the truth, we reason to justify what we already believe.”
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Reposted by Ghanendra Singh
Ciaran Murphy-Royal @murphyroyallab.org · 11/02/2026
Really nice work from the Holmes lab looking at amygdala astrocytes in fear memory and extinction! www.nature.com/articles/s41...
nature.com
Astrocytes enable amygdala neural representations supporting memory - Nature
Astrocytes in the basolateral amygdala dynamically track fear state and support fear memory retrieval and extinction.
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Reposted by Ghanendra Singh
Navarrete Lab @navarrete-llinas.bsky.social · 14/01/2026
🎉 Great news! Our paper is now published in @naturecomm We identify a specific astrocyte ensemble that mediates THC-induced cognitive impairments during adolescence Huge thanks to our collaborators @marsicanolab @khakhlab @grandeslab 🔗 rdcu.be/eY0Or @jsromero.bsky.social @crismonteagudo.bsky.social
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Ghanendra Singh @ghanendra.bsky.social · 19/01/2026
Scientific knowledge flourishes as a non zero-sum nature, nurtured by intellectual freedom and shared inquiry. However, this beauty is frequently undermined by systems that operate on zero-sum logic.
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Ghanendra Singh @ghanendra.bsky.social · 15/01/2026
Elegance of a model lies in the simplicity of predicting a phenomena emerged based on intuitive believe 🤔, and understanding of the nature of reality captured by abstract imagination 💭 that are observed experimentally 👀, realised or discovered at a later stage.
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Ghanendra Singh @ghanendra.bsky.social · 14/01/2026
Human 🩸🧠⏹️ #BBB on a chip 🤩
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Ghanendra Singh @ghanendra.bsky.social · 14/01/2026
Microglia and Astrocytes in ASD.
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Reposted by Ghanendra Singh
Arman Behrad @armanbehrad.bsky.social · 08/01/2026
Wanna compare dynamics across neural data, RNNs, or dynamical systems? We got a fast and furious method🏎️ The 1st preprint of my PhD 🥳 fast dynamical similarity analysis (fastDSA): 📜: arxiv.org/abs/2511.22828 💻: github.com/CMC-lab/fast... I’ll be @cosynemeeting.bsky.social - happy to chat 😉
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Bertoglio lab (FMC/UFSC) @bertogliolab.bsky.social · 01/01/2026
Distinct endocannabinoids specifically signal to astrocytes or neurons in the adult mouse hippocampus www.nature.com/articles/s41...
nature.com
Distinct endocannabinoids specifically signal to astrocytes or neurons in the adult mouse hippocampus - Nature Neuroscience
Distinct endocannabinoids signal to either astrocytes or neurons, evoking contrasting regulation of synaptic function. This works reveals the high degree of complexity of neuronal and astrocytic signa...
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Reposted by Ghanendra Singh
Neuroscience Initiative at the CUNY ASRC @asrcneuroscience.bsky.social · 08/01/2026
📢Join our first seminar in 2026! Anna Orr, PhD, Associate Professor of Neuroscience at Weill Cornell, will give a talk on “Astrocytes in Neurocognitive Function and Dementia Pathogenesis” on Thursday, January 15.
Flyer for January 15 , 2026 seminar of the Spring 2026 Seminar Series
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Ghanendra Singh @ghanendra.bsky.social · 11/01/2026
ECMTB ecmtb2026.org by SMB @smbmathbiology.bsky.social and ESMTB @esmtbio.bsky.social 🤩
ecmtb2026.org
European Conference on Mathematical & Theoretical Biology 2026
ECMTB is coming to Graz, Austria in July 2026. Registration and Call for Contributions are open!
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Reposted by Ghanendra Singh
ESMTB @esmtbio.bsky.social · 19/12/2025
International Conference on Mathematical Neuroscience @ McGill University, Montreal, Canada 2 – 5 Jun 2026 www.crmath.ca/en/activitie...
crmath.ca
Activities - Site officiel du Centre de recherches mathématiques (CRM)
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Reposted by Ghanendra Singh
Network Glia | European Glia Meeting @gliameeting.bsky.social · 18/12/2025
ATgliaNet Symposium 2026 March 20th, 2026 | Vienna Keynote speaker Prof. Leda Dimou (University of Ulm) Registration & abstract submission until Feb 13: loom.ly/33SkUKk Find more glia related meetings here: loom.ly/dwKZ1r8
hirnforschung.meduniwien.ac.at
ATgliaNet Symposium 2026, March 20th, 2026 | MedUni Wien
Following last year’s successful inaugural symposium at ISTA, we are proud to announce the ATgliaNet Symposium 2026, a one-day scientific meeting, with keynote speaker Prof. Leda Dimou (Medical Faculty, University of Ulm).
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Ghanendra Singh @ghanendra.bsky.social · 11/01/2026
Astrocytes tuning plasticity during critical periods !!
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Reposted by Ghanendra Singh
Federation of European Neuroscience Societies - FENS @fens.org · 09/01/2026
🌟 Only 6 months until #FENS2026! Soon, the #neuroscience community will come together to exchange ideas and explore the latest breakthroughs in neuroscience. 🧠 📍 Barcelona, Spain 🗓️ 6–10 July 2026 👉 Learn more and join us in #Barcelona: fensforum.org #FENS #FENSForum #NeuroscienceConference
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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 10/01/2026
Astrocytes control oxytocin-based maternal behavior via connexin 30 www.biorxiv.org/content/10.64898/20…
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Reposted by Ghanendra Singh
Earl K. Miller @earlkmiller.bsky.social · 09/01/2026
New results! Computational models often rely on hand-crafted connectivity and imposed dynamics to produce traveling waves (TWs). We show how TWs can naturally emerge under biologically plausible conditions. Emergent Traveling Waves in Neural Circuits doi.org/10.64898/202... #neuroscience
doi.org
Emergent Traveling Waves in Neural Circuits
Artificial neural networks achieve striking performance but do not capture a prominent neural property. Cortical activity is organized by structured spatiotemporal dynamics, traveling waves (TW), whic...
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Reposted by Ghanendra Singh
Earl K. Miller @earlkmiller.bsky.social · 09/01/2026
Many cortical traveling waves spiral. Here's how and why. Cortical Field Model of Complex Spiral Traveling Waves doi.org/10.64898/202... #neuroscience
doi.org
Cortical Field Model of Complex Spiral Traveling Waves
Complex spiral traveling waves observed experimentally occurs across the cortex. The underlying mechanisms responsible for generating such mesoscopic activity are not well understood. Understanding ho...
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Ghanendra Singh @ghanendra.bsky.social · 09/01/2026
Wow !! Another RNN based #TravelingWave #TW mechanistic model for cortical computation. In future: 🌊 Prop > 🔙 Prop 🤩.
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Ciaran Murphy-Royal @murphyroyallab.org · 08/01/2026
Delighted to share our first preprint of the year! A project that we're all really proud of in the lab led by @ossamaghenissa.bsky.social with @mathiasgua.bsky.social in which we set out to test the role of basolateral amygdala astrocytes in anxiety behaviour. www.biorxiv.org/content/10.6...
biorxiv.org
Astrocytic Encoding of Threat in the Basolateral Amygdala
The basolateral amygdala (BLA) has long been implicated in threat detection and the generation of anxiety states. While previous experiments have demonstrated the important role of BLA principal neuro...
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Reposted by Ghanendra Singh
arxiv cs.NE @arxiv-cs-ne.bsky.social · 06/01/2026
RMAAT: Astrocyte-Inspired Memory Compression and Replay for Efficient Long-Context Transformers arxiv.org/abs/2601.00426
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Ghanendra Singh @ghanendra.bsky.social · 08/01/2026
Beautiful 🤩 !! Function as CIM.
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Ghanendra Singh @ghanendra.bsky.social · 08/01/2026
Complex #spiral #traveling-waves across the cortex.
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Ghanendra Singh @ghanendra.bsky.social · 08/01/2026
Modeling endfeet aging of BBB in PFC might give us interesting insights.
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Ghanendra Singh @ghanendra.bsky.social · 08/01/2026
MERCs in astrocytic brain aging.
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The Science of Parkinson's @scienceofpd.bsky.social · 08/01/2026
Mitochondrial transfer from satellite glial cells (SGC) to neurons protects against peripheral neuropathy; SGCs are capable of transferring mitochondria to dorsal root ganglia sensory neurons in vitro, ex vivo & in vivo (via tunnelling nanotubes) www.nature.com/articles/s41...
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Reposted by Ghanendra Singh
European Microglia Webinar Series @microgliaseries.bsky.social · 08/01/2026
Happy new year everyone 🍾 To start the year we have a new webinar coming soon! Prof. Bo Peng from the Institute for Translational Brain Research in China will be our next speaker on January 13th. Check all the information in the flyer and add it to your calendar! 🧬🧠
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Ghanendra Singh @ghanendra.bsky.social · 07/01/2026
Possibly a significant role in the Long Term WM based dynamics.
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Ghanendra Singh @ghanendra.bsky.social · 07/01/2026
True, an interesting way of looking at the brain computing dynamics.
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Ghanendra Singh @ghanendra.bsky.social · 07/01/2026
Beauty of #spiral-waves even in the fertilized eggs 🤩 ComplexSystems dynamics !! news.mit.edu/2020/growth-...
news.mit.edu
The growth of an organism rides on a pattern of waves
An MIT study finds waves that ripple across a newly fertilized egg are similar to the waves in seemingly unrelated systems, from ocean and atmospheric circulations to quantum fluids.
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Ghanendra Singh @ghanendra.bsky.social · 06/01/2026
Astrocytes with slow and fast calcium dynamics seen from reinforcement learning framework. 2026 💥
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Ghanendra Singh @ghanendra.bsky.social · 05/01/2026
Now What? 🔖
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Reposted by Ghanendra Singh
bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 03/01/2026
Spatiotemporally distinctive astrocytic and neuronal responses to repetitive intracortical microstimulation www.biorxiv.org/content/10.64898/20…
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Ghanendra Singh @ghanendra.bsky.social · 05/01/2026
Astrocytic Engrams !! 🤩
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Reposted by Ghanendra Singh
UK Glia Network @ukglia.bsky.social · 05/01/2026
📢 Registration for our second UK Glia meeting (8–9 June 2026) is open! Abstracts must be submitted by 16 Jan. 👉 www.physoc.org/events/uk-gl... Our next speaker is Giles Hardingham from UK DRI @ukdri.ac.uk and the University of Edinburgh @edinburgh-uni.bsky.social
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Ghanendra Singh @ghanendra.bsky.social · 05/01/2026
From astrocytes to spiking neural networks !!
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Ghanendra Singh @ghanendra.bsky.social · 22/12/2025
An earlier late breaking news talk on switching dynamics in working memory model showing complex MMOs proposed for efficient WM hardware implementation using SNNs in March at NICE 2025. www.youtube.com/watch?v=zVDu...
youtube.com
24 - Ghanendra Singh (TU Graz, Austria) - Late breaking news
YouTube video by Neuro Inspired Computational Elements Conference
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Reposted by Ghanendra Singh
Salk Institute @salkinstitute.bsky.social · 19/12/2025
Scientists at the Salk Institute have now discovered a molecule that is critical for stabilizing brain circuits in adulthood: a protein called CCN1 secreted by star-shaped cells called astrocytes. www.salk.edu/news-release...
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Ghanendra Singh @ghanendra.bsky.social · 17/12/2025
Human model of the BBB for NVD.
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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 11/12/2025
Cortical astrocytes flexibly encode reward contingencies and shape conditioned behavior www.biorxiv.org/content/10.64898/20…
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Eric Topol @erictopol.bsky.social · 03/12/2025
The outsized role of our brain astrocytes nature.com/articles/d41...
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Eric Topol @erictopol.bsky.social · 24/11/2025
Semaglutide (Ozempic) failed to have clinical impact for slowing progression in people with mild Alzheimer’s disease in 2 large, placebo-controlled trials novonordisk.com/content/nnco...
novonordisk.com
News Details
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Reposted by Ghanendra Singh
Emulate, Inc. @emulatebio.bsky.social · 18/11/2025
🧪🧠 The first isogenic, five-cell #OrganOnChip model of the human neurovascular unit is now here! Brain-Chip R1 brings together neurons, astrocytes, microglia, pericytes, and BMECs in a dynamic, perfused system that captures key features of the BBB and NVU—built for more predictive CNS research.
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Søren Grubb @sorengrubb.bsky.social · 20/11/2025
New on bioRxiv! 🚨 “Pericyte and Endothelial Primary Cilia and Centrioles have Disparate Organization Across the Brain Microvasculature” This project studying #microvascular cells took an unexpected turn when we discovered that #pericytes have primary #cilia! 🔗 www.biorxiv.org/content/10.1... 🧪 🧵1/8
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Blanca Díaz Castro @bdiazcastro.bsky.social · 06/11/2025
Finally it’s here! 🌟⬇️ www.nature.com/articles/s41... I’m sooo excited to share our latest article led by Steve Hill and Isabel Bravo-Ferrer 1- How does the vasculature communicate with astrocytes? 2- Is this communication dependent to what happens in the body. 3- Is it relevant to human diseases?
nature.com
Fig. 1: Establishment of methods to identify astrocyte endfoot proteins. | Nature Communications
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Wendy Xin @droligo.bsky.social · 29/10/2025
If you are attending #SfN25, please join @amygleichman.bsky.social and I on Monday at 9PM for a casual social gathering to discuss all things non-neuronal! Date: Monday, Nov 17th Time: 9PM till close Location: The Smoking Gun SD, 555 Market St. All welcome, please free to spread the word!
A flyer displaying the same information as written in the post, with two images of two astrocytes around a blood vessel and one newly formed oligodendrocyte, along with logs our sponsors Avantor and Plasmidsaurus.
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Neuron @cp-neuron.bsky.social · 04/10/2025
dlvr.it
Neuromorphic is dead. Long live neuromorphic
In this NeuroView, Giacomo Indiveri discusses the origins and evolution of neuromorphic engineering, reflects on recent shifts toward digital and AI-centric approaches, and advocates for a revival of the field’s original principles, emphasizing analog, brain-inspired systems and the importance of fundamental neuroscience for future progress.
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Ghanendra Singh @ghanendra.bsky.social · 22/10/2025
Decoding Leaky-BBB 🧠 together with @astrocytenet.bsky.social and @dibenedetto-lab.bsky.social 🤩.
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