A new AI for Biological Discovery Seminar Series, presented by the Francis Crick Institute.

Our clinical training pathway integrating AI and machine learning with discovery research.

Scientific discovery seeks mechanisms that explain observations and predict beyond the measurements that produced them. Whereas large language models (LLMs) encode knowledge implicitly, mechanistic wo...

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Small gene regulatory circuits can encode a surprising diversity of dynamical behaviors. A biophysical model of the AC-DC motif reveals over thirty distinct bifurcation structures and shows how molecu...

Inside OpenAI, coding agents are reshaping AI research. Explore early data on agent usage, experiment velocity, task complexity, and research acceleration.

A prospective, blinded competition is conducted for artificial-intelligence-generated and optimized antibody discovery.

Salary for this Role: From £47,500, with benefits, subject to skills and experience. Job Title: Postdoctoral Fellow - Frohlich Lab Reports to: Fabian Frohlich Closing Date: 24/Sept/2026 23.59 GMT Job ...

A new AI for Biological Discovery Seminar Series, presented by the Francis Crick Institute.

A walk through a modern apartment, through the eyes of the people for whom everything in it was new.

Neural ordinary differential equations (NODEs) and universal differential equations (UDEs) provide flexible and popular frameworks for learning interpretable dynamical systems from noisy time-series d...

A report on a series of mini machine learning projects, executed with, and mostly by, Claude

Protein sequences are constrained not only by the need to fold into stable structures, but also by specific functional requirements imposed by natural selection. Yet predictions of how amino-acid chan...

Cells sense and respond to their environment through signalling pathways, and the dynamics of these pathways shape cell fate even within genetically identical populations. Two largely separate computa...

The postwar bargain at the heart of higher education is coming undone. What replaces it?

Kondo, Notbohm, et al. show that the BRAF N-terminal acidic motif engages the dimeric interface to drive an asymmetric arrangement in which only one protomer adopts a canonical active kinase conformation. Captured MEK1 Ser222 phosphorylation and mutational analysis corroborate that this motif is required for full BRAF kinase activity.

Nature Reviews Genetics - Genetic variation influences biological processes across scales; however, deciphering how effects propagate from molecules to whole organisms remains a key challenge in...

Biologically inspired neural networks (BINNs) embed pathway, ontology, or protein-interaction structure directly into neural networks, promising interpretable disease prediction where hidden nodes map...

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A biology journal that paid peer reviewers found that the approach cut the time to a first editorial decision by 85% and maintained high-quality reviews.

Claude Science is a customizable app that integrates the tools and packages researchers most often use, produces auditable artifacts, and provides flexible access to computing resources.

The Francis Crick Institute has appointed Professor Mihaela van der Schaar as its Chief AI Scientist, advancing its ambition to combine artificial intelligence with fundamental biology and medicine, c...

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Summary: This Editorial offers an honest look at impact factor trends in developmental biology, explains how Development serves its community, and makes the case that sustaining developmental biology ...

Over the last thirteen years, bioRxiv and medRxiv have grown into widely used infrastructure for rapid research sharing in biology and medicine. The reliability and researcher-first values that have d...

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